 |
- Condition: Parkinson
Interventions: Other: Surface EMG, MRI and PET Scan; Other: Surface EMG
Sponsors: Spaulding Rehabilitation Hospital; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Condition: Parkinson Disease
Intervention: Other: 9zest app facilitated exercise
Sponsors: 9zest. Inc.; University of Nevada, Las Vegas; Boston University
Recruiting - Condition: Parkinson Disease
Intervention: Device: Boston Scientific Vercise PC IPG with directional DBS lead
Sponsors: University of Alabama at Birmingham; National Institutes of Health (NIH); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Interventions: Drug: P2B001; Drug: Rasagiline; Drug: Pramipexole; Drug: Pramipexole ER
Sponsor: Pharma Two B Ltd.
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Computer task assessing cognition; Behavioral: Impulsive-Compulsive Disorders in Parkinson's Disease; Behavioral: Montreal Cognitive Assessment
Sponsor: University of Florida
Recruiting - Condition: Parkinson's Disease
Interventions: Dietary Supplement: Niacin; Dietary Supplement: Niacinamide; Other: Placebo
Sponsor: VA Office of Research and Development
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: Medtronic DBS Therapy for Parkinson's disease
Sponsor: MedtronicNeuro
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Duke University
Recruiting - Condition: Parkinson's Disease
Intervention: Device: Bioinduction "Picostim" Deep Brain Stimulation system
Sponsors: North Bristol NHS Trust; Bioinduction
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: safinamide metansolfonato (12 weeks); Drug: rasagilina mesilato (12 weeks)
Sponsors: Universita di Verona; Azienda Ospedaliera Universitaria Integrata Verona
Recruiting - Condition: Parkinson Disease
Interventions: Other: Training with Neurofeedback; Other: The other Training with Neurofeedback
Sponsors: Osaka University; Japan Agency for Medical Research and Development
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Nabilone 0.25 mg
Sponsor: Medical University Innsbruck
Recruiting - Condition: Parkinson Disease
Intervention: Diagnostic Test: Clinical evaluation of vision and eye tests
Sponsor: Neuromed IRCCS
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Nabilone 0.25 mg; Drug: Placebo
Sponsor: Medical University Innsbruck
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: Rush University Medical Center; California Institute of Technology; Purdue University
Recruiting - Condition: Parkinson Disease
Interventions: Drug: DNL201 low dose; Drug: DNL201 high dose; Drug: Placebo
Sponsor: Denali Therapeutics Inc.
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: Apomorphine; Other: Best Medical Treatment
Sponsor: Rennes University Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Other: Donor FMT; Other: Autologous FMT
Sponsors: University Ghent; University Hospital, Ghent; the Flanders Institute for Biotechnology; Research Foundation Flanders; Parkinson's disease patient organizations: Vlaamse Parkinson Liga, Parkili
Recruiting - Condition: Parkinson Disease
Intervention: Biological: Injection of Umbilical cord derived MSCs
Sponsor: University of Jordan
Recruiting - Condition: Parkinson Disease
Interventions: Drug: OXB-102; Other: Imitation Surgical Procedure (ISP)
Sponsors: Oxford BioMedica; Axovant Sciences Ltd.
Recruiting - Condition: Parkinson Disease
Interventions: Dietary Supplement: Nicotinamide Riboside; Drug: Placebo
Sponsor: Haukeland University Hospital
Not yet recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Motivational Interviewing; Behavioral: Web-based application
Sponsors: Shirley Ryan AbilityLab; National Institute on Disability, Independent Living, and Rehabilitation Research
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Experimental training; Behavioral: Control training
Sponsors: University of Sao Paulo General Hospital; University of Brasilia; Universidade Federal do Rio Grande do Norte
Not yet recruiting - Condition: Parkinson
Interventions: Drug: Buspirone; Drug: Placebo
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Universita di Verona
Recruiting - Condition: Parkinson Disease
Interventions: Diagnostic Test: UPDRS questionnaires; Diagnostic Test: 20-step walking test
Sponsors: Satakunta Central Hospital; Tampere University of Technology
Recruiting - Condition: Parkinson's Disease
Interventions: Behavioral: Aerobic walking; Behavioral: Usual care with PD specific health education
Sponsors: VA Office of Research and Development; University of Iowa
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Deferiprone; Drug: Placebo
Sponsors: University Hospital, Lille; European Commission; ApoPharma
Recruiting - Condition: Parkinson Disease
Interventions: Device: Exablate Subthalamotomy; Device: Sham Exablate Subthalamotomy
Sponsor: InSightec
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Liraglutide; Drug: Placebo
Sponsors: Cedars-Sinai Medical Center; The Cure Parkinson's Trust; Novo Nordisk A/S
Recruiting - Condition: Parkinson's Disease Dementia
Interventions: Drug: Ceftriaxone; Other: Placebo
Sponsor: BrainX Corporation
Recruiting - Condition: Parkinson Disease
Interventions: Dietary Supplement: N-Acetylcysteine; Procedure: Lumbar Puncture
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: behavioral observation
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - Condition: Parkinson Disease
Interventions: Device: Robot-assisted gait training; Device: Intensive treadmill training
Sponsors: Seoul National University Hospital; National Rehabilitation Center, Seoul, Korea
Recruiting - Condition: Parkinson Disease
Intervention: Other: Investigation of self-perception in Parkinson's disease
Sponsors: Sheba Medical Center; Bar-Ilan University, Israel
Recruiting - Condition: Parkinson Disease
Interventions: Other: Game based treadmill Platform; Other: Control Group
Sponsor: University of Manitoba
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: PF-06412562; Drug: Standard of Care Placebo
Sponsors: Milton S. Hershey Medical Center; Pfizer
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: Physical Therapy
Sponsors: Washington University School of Medicine; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - Condition: Parkinson Disease
Interventions: Other: mHealth delivered exercise program; Other: Exercise only
Sponsors: Boston University Charles River Campus; Washington University School of Medicine
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: University of Washington
Recruiting - Condition: Parkinson Disease
Interventions: Device: RMBand lower dose; Device: RMBand higher dose
Sponsor: Virginia Commonwealth University
Recruiting - Condition: Parkinson's Disease
Intervention: Other: Identification of genes
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Live movement observation (Upper Limbs); Behavioral: Video Observation (Upper Limbs); Behavioral: Live Movement Observation (Lowe Limbs); Behavioral: Video Observation (Lower Limbs); Behavioral: Static Picture Observation and Upper Limbs Exercise; Behavioral: Static Picture Observation and Lower Limbs Exercise
Sponsors: IRCCS San Camillo, Venezia, Italy; University of Genova; Università Politecnica delle Marche
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Rivastigmine transdermal patch
Sponsors: University of Maryland; National Institute on Aging (NIA)
Not yet recruiting - Condition: Parkinson Disease
Intervention: Radiation: MRI if indicated
Sponsor: Alaa E Ahmed
Not yet recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Stepping-in-place exercise with external auditory cues; Device: Transcranial magnetic stimulation (TMS)
Sponsor: HsiuYun Chang
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: SQJZ herbal mixtures; Drug: Placebo
Sponsor: Dongzhimen Hospital, Beijing
Recruiting - Condition: Parkinson Disease
Interventions: Device: Training with HWA device; Other: Usual Care
Sponsors: Ohio State University; Michael J. Fox Foundation for Parkinson's Research; Honda Research and Development Americas, Inc
Not yet recruiting - Condition: Parkinson's Disease
Interventions: Other: Cycling at Forced rate; Other: Cycling at self-selected rate
Sponsors: Shirley Ryan AbilityLab; Paul Ruby Foundation for Parkinson's Research; Northwestern Memorial Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Karate Classes; Behavioral: Pre-Intervention Focus Group; Behavioral: Post-Intervention Focus Group
Sponsor: Rush University Medical Center
Recruiting - Condition: Parkinson Disease
Interventions: Genetic: Identification of COMT HH, COMT HL or COMT LL genes; Other: Brain MRI with resting state scan; Other: Brain MPET
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: Continuous intrajejunal infusion of levodopa-carbidopa; Device: deep brain stimulation
Sponsors: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); ZonMw: The Netherlands Organisation for Health Research and Development
Recruiting - Condition: Parkinson's Disease
Intervention: Drug: Accordion Pill™ Carbidopa/Levodopa
Sponsor: Intec Pharma Ltd.
Recruiting - Condition: Parkinson Disease
Intervention: Device: Spinal cord stimulation
Sponsor: Western University, Canada
Recruiting - Condition: Parkinson Disease
Interventions: Biological: VY-AADC02; Other: Placebo
Sponsor: Voyager Therapeutics
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Ganoderma; Drug: Placebos
Sponsor: Xuanwu Hospital, Beijing
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Cannabidiol; Other: Placebo
Sponsors: University of Colorado, Denver; Colorado Department of Public Health and Environment
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Strategy Training; Behavioral: Process Training; Behavioral: Control Group
Sponsor: Washington University School of Medicine
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Semaglutide
Sponsor: Oslo University Hospital
Not yet recruiting - Condition: Parkinson Disease
Interventions: Other: Neurologic Music Therapy; Other: Occupational Therapy; Other: Music Supported Therapy
Sponsors: University of Colorado, Denver; National Center for Complementary and Integrative Health (NCCIH)
Recruiting - Condition: Parkinson's Disease
Intervention: Other: Light exposure
Sponsors: Massachusetts General Hospital; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson's Disease
Intervention: Drug: Gold Nanocrystals
Sponsors: Clene Nanomedicine; University of Texas Southwestern Medical Center
Not yet recruiting - Condition: Parkinson's Disease
Interventions: Combination Product: Experimental: INP103; Combination Product: Placebo
Sponsor: Impel NeuroPharma Inc.
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: National Parkinson Foundation
Recruiting - Condition: Parkinson's Disease
Interventions: Device: TENS; Device: Control
Sponsor: University Hospital, Toulouse
Recruiting - Condition: Parkinson Disease
Intervention: Device: Electrophysiological recording and measurement devices
Sponsors: Prof. Dr. Volker Arnd Coenen; University of Freiburg
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Placebo oral capsule; Drug: PXT002331 - dose 1; Drug: PXT002331 - dose 2
Sponsor: Prexton Therapeutics
Recruiting - Condition: Parkinson Disease
Intervention: Drug: DPA-714-PET/MRI
Sponsor: University of Alabama at Birmingham
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: Handwriting Practice
Sponsors: Oxford Brookes University; European Parkinson’s Therapy Centre
Recruiting - Condition: Parkinson Disease
Intervention: Genetic: biomarker identification in Parkinson disease
Sponsor: Neuromed IRCCS
Not yet recruiting - Condition: Parkinson Disease
Intervention: Other: multilimb dual task
Sponsors: A.T. Still University of Health Sciences; National Institute of Neurological Disorders and Stroke (NINDS); University of Idaho; Mayo Clinic
Recruiting - Condition: Parkinson Disease
Interventions: Drug: KDT-3594; Drug: Pramipexole
Sponsor: Kissei Pharmaceutical Co., Ltd.
Recruiting - Condition: Parkinson Disease
Interventions: Other: Exercise training; Behavioral: Sleep hygiene
Sponsors: University of Alabama at Birmingham; Parkinson's Disease Foundation
Recruiting - Condition: Parkinson Disease
Interventions: Other: Patient assessment; Radiation: DATScan; Radiation: Orbital X-Ray; Other: Magnetic Resonance Imaging (MRI)
Sponsors: University of Nottingham; Michael J. Fox Foundation for Parkinson's Research; National Institute for Health Research, United Kingdom
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Qigong exercise; Behavioral: Mild body exercise
Sponsor: University of Kansas Medical Center
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Donepezil; Drug: Placebo
Sponsors: Oregon Health and Science University; Medical Research Foundation, Oregon
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: University Hospital, Lille
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Ioflupane I 123
Sponsor: Julie Gurwell
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Dance Therapy; Behavioral: exercises without dance
Sponsor: Ospedale Generale Di Zona Moriggia-Pelascini
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Rifaximin; Other: Placebo
Sponsors: University of California, San Francisco; Nova Southeastern University
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: Omnidirectional Deep Brain Stimulation of STN; Device: Directional Deep Brain Stimulation of STN
Sponsors: University Hospital Tuebingen; Abbott
Recruiting - Condition: Parkinson Disease
Intervention: Device: transcranial magnetic stimulation
Sponsor: University Hospital, Grenoble
Not yet recruiting - Condition: Parkinson Disease
Interventions: Behavioral: non-random whole body vibration; Behavioral: occupational therapy
Sponsor: Chang Gung University
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: Assistive Technology Clinic, Canada; University of Cincinnati; The Cleveland Clinic; University Health Network, Toronto; University of Michigan; Rush University; The Parkinson Study Group
Recruiting - Condition: Parkinson's Disease
Interventions: Dietary Supplement: niacin; Other: placebo
Sponsor: VA Office of Research and Development
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - Condition: Parkinson Disease
Interventions: Genetic: Cohort1; Genetic: Cohort2
Sponsors: Jichi Medical University; Takara Bio Inc.; Gene Therapy Research Institution,Co.,Ltd.
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Ips-nsc cells
Sponsors: Allife Medical Science and Technology Co., Ltd.; The First People's Hospital of Yunnan Province/First People's Hospital of Yunan Provinve New Kunhua Hospital; Henan Provincial Hospital; Beijing Hospital
Not yet recruiting - Condition: Parkinson Disease
Intervention: Drug: Cannabis Oil
Sponsors: University Health Network, Toronto; Parkinson Society Canada
Not yet recruiting - Condition: Parkinson Disease
Interventions: Other: cognitive examination; Other: viewing of video; Other: Iowa Gambling Task
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Clarithromycin; Drug: Placebo
Sponsors: Nicolaas Bohnen, MD, PhD; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Intervention: Drug: 11C-PiB
Sponsor: Oriental Neurosurgery Evidence-Based-Study Team
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Zolpidem; Other: Placebo
Sponsors: Aston University; University Hospital Birmingham NHS Foundation Trust
Recruiting - Condition: Parkinson's Disease
Intervention: Other: Gait training
Sponsors: VA Office of Research and Development; University of Washington
Recruiting - Condition: Parkinson Disease
Interventions: Other: Scalp Acupuncture; Other: Body Acupenture
Sponsor: Taipei Veterans General Hospital, Taiwan
Not yet recruiting - Condition: Parkinson Disease
Intervention: Drug: sargramostim
Sponsor: University of Nebraska
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: AMPS Gondola; Device: Sham Gondola
Sponsor: IRCCS San Raffaele
Recruiting - Condition: Parkinson Disease
Intervention: Other: Rapid Cadence Cycling on a Solo-Rider Spin Bicycle
Sponsors: Massachusetts General Hospital; The Cleveland Clinic
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Flumazenil; Drug: Placebo
Sponsors: University of Michigan; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Intervention: Dietary Supplement: Oral D-Mannitol of Placebo
Sponsor: Hadassah Medical Organization
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: Speech-to-noise feedback
Sponsors: Lawson Health Research Institute; University of Western Ontario, Canada
Not yet recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Home Visit Program; Behavioral: Caregiver Mentorship Program
Sponsor: Rush University Medical Center
Recruiting - Condition: Parkinson Disease
Interventions: Drug: THN102 Dosage A; Drug: THN102 Dosage B; Drug: THN102 Dosage C
Sponsor: Theranexus
Recruiting - Condition: Parkinson Disease
Interventions: Procedure: Osteopathic Manipulative Treatment (OMT); Other: Light Touch
Sponsor: University of California, San Diego
Recruiting - Condition: Parkinson Disease
Intervention: Diagnostic Test: Nasal swab
Sponsor: Rush University Medical Center
Recruiting - Condition: Parkinson Disease
Intervention: Device: Spinal Cord Stimulator (SCS)
Sponsor: Nora Vanegas-Arroyave
Not yet recruiting - Condition: Parkinson's Disease
Intervention: Drug: Ursonorm
Sponsors: Sheffield Teaching Hospitals NHS Foundation Trust; J P Moulton Charitable Foundation; PRO.MED.CS Praha a.s.; Clinical Trials Research Unit, University of Sheffield
Recruiting - Condition: Parkinson Disease
Interventions: Drug: IPT803; Genetic: Optional pharmacogenetic assessment; Other: Questionnaires; Other: Optional Blood-Oxygen-level Dependent functionalMRI; Other: Motor Assessments before taking regular PD treatment; Other: Motor Assessments on regular PD treatment
Sponsor: Tools4Patient
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: KW-6356; Drug: Placebo
Sponsor: Kyowa Hakko Kirin Co., Ltd
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Droxidopa; Drug: Carbidopa
Sponsors: Vanderbilt University Medical Center; H. Lundbeck A/S; American Academy of Neurology
Recruiting - Condition: Parkinson's Disease Dementia
Interventions: Drug: LY3154207; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Condition: Parkinson's Disease
Intervention: Biological: mesenchymal stem cells
Sponsor: Hebei Newtherapy BIo-Pharma technology Co., Ltd.
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Aarhus University Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Other: PD neurofeedback; Other: PD control
Sponsor: Yale University
Recruiting - Condition: Parkinson Disease
Interventions: Drug: PRIM-DJ2727; Drug: Placebo oral capsule
Sponsors: The University of Texas Health Science Center, Houston; Kelsey Seybold Research Fundation
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Lixisenatide; Drug: placebo
Sponsors: University Hospital, Toulouse; Cure Parkinson; Réseau NS-Park; EUCLID; Sanofi
Recruiting - Condition: Parkinson Disease
Intervention: Drug: [18F]DPA-714 PET scan
Sponsor: Nantes University Hospital
Recruiting - Condition: Parkinson Disease
Intervention: Device: Deep Brain Stimulation
Sponsor: University of Colorado, Denver
Recruiting - Condition: Parkinson Disease
Intervention: Other: No Intervention - Observational Study
Sponsors: Oregon Health and Science University; Portland VA Medical Center; Oregon Clinical and Translational Research Institute
Recruiting - Condition: Parkinson's Disease
Intervention: Biological: Intracerebral microinjections
Sponsor: NeuroGeneration
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: e-Tapper TT-R1
Sponsor: Boston University
Recruiting - Condition: Parkinson Disease
Intervention: Device: Stimulation
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: PAT sessions
Sponsor: New York University School of Medicine
Recruiting - Condition: Parkinson Disease
Interventions: Device: adaptive Deep Brain Stimulation; Device: conventional Deep Brain Stimulation
Sponsor: Newronika
Recruiting - Condition: Parkinson Disease
Intervention: Other: Personalized activity program
Sponsor: Centre Hospitalier Universitaire de Nīmes
Recruiting - Condition: Parkinson Disease
Intervention: Drug: ursodeoxycholic acid
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting - Condition: Idiopathic Parkinson Disease
Interventions: Behavioral: Lee Silverman Voice Treatment; Device: SpeechVive; Behavioral: Control
Sponsors: University of Massachusetts, Amherst; National Institute on Deafness and Other Communication Disorders (NIDCD); Purdue University
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Accordion Pill Carbidopa/Levodopa; Drug: Sinemet CR 25Mg-100Mg Extended-Release Tablet
Sponsor: Intec Pharma Ltd.
Not yet recruiting - Condition: Parkinson Disease Psychosis
Interventions: Drug: SEP-363856; Drug: Placebo capsule
Sponsor: Sunovion
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: BIIB054; Drug: Placebo
Sponsor: Biogen
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Infudopa i.v.; Drug: Infudopa s.c.; Drug: LCIG (Duodopa)
Sponsors: Vastra Gotaland Region; The Swedish Research Council; Dizlin Medical Design AB; Göteborg University
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Rhythmic Auditory Stimulation; Behavioral: Kinesiology
Sponsors: Pontifical Catholic University of Argentina; National Council of Scientific and Technical Research, Argentina; Hospital Nacional Profesor Alejandro Posadas; University of Buenos Aires
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Donepezil; Drug: Placebos
Sponsor: Kyung Hee University Hospital
Recruiting - Condition: Parkinson's Disease
Interventions: Device: active light therapy : Light therapy: DayVia lamp 10000 lux; Device: Placebo light therapy
Sponsor: University Hospital, Strasbourg, France
Recruiting - Condition: Motor OFF Episodes Associated With Parkinson's Disease
Interventions: Drug: APL-130277; Drug: subcutaneous apomorphine
Sponsor: Sunovion
Recruiting - Condition: Parkinson's Disease
Interventions: Device: CloudUPDRS smartphone software assessment; Other: Clinical assessment
Sponsor: University College, London
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: Placebo; Drug: BIIB054
Sponsor: Biogen
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Pramipexole SR; Drug: Pramipexole IR
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Parkinson Disease
Interventions: Other: Rhythm workers training Perceptive timing; Other: Rhythm workers training sensorimotor timing; Other: No Rhythm workers training
Sponsors: University Hospital, Montpellier; Laboratory Parole et Langage UMR 7309; Laboratory EUROMOV EA 2991; Université Montpellier
Recruiting - Condition: Idiopathic Parkinson Disease
Intervention:
Sponsor: University of Southern California
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: University of Michigan
Recruiting - Condition: Parkinson Disease
Interventions: Other: Transcranial Magnetic Stimulation; Behavioral: Lee Silverman Voice Treatment
Sponsors: Le Bonheur Children's Hospital; Michael J. Fox Foundation for Parkinson's Research; University of Tennessee Health Science Center; University of Memphis
Recruiting - Condition: Early Parkinson Disease
Interventions: Drug: K0706; Other: placebo
Sponsor: Sun Pharma Advanced Research Company Limited
Recruiting - Condition: Parkinson Disease
Intervention: Procedure: Variable Frequency Stimulation
Sponsor: Beijing Pins Medical Co., Ltd
Recruiting - Condition: Parkinson's Disease (Disorder)
Interventions: Drug: IR CD-LD; Drug: IPX203 ER CD-LD; Other: IPX203 placebo; Other: IR CD-LD placebo
Sponsor: IMPAX Laboratories, Inc.
Recruiting - Conditions: Parkinson Disease, PARK8; Parkinson Disease; Idiopathic Parkinson Disease
Intervention:
Sponsors: King's College London; GlaxoSmithKline
Not yet recruiting - Condition: Parkinson's Disease
Intervention: Other: patients with Parkinson's disease
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Condition: Parkinson Disease
Intervention: Biological: ISC-hpNSC
Sponsor: Cyto Therapeutics Pty Limited
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: Rasagiline; Other: Placebo; Device: Magnetic Resonance Imaging; Device: functional Magnetic Resonance Imaging; Other: Physical Function Performance Test
Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: GZ/SAR402671; Drug: Placebo
Sponsor: Genzyme, a Sanofi Company
Recruiting - Condition: Parkinson Disease
Interventions: Drug: GRF6021; Other: Placebo
Sponsors: Alkahest, Inc.; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Condition: Parkinson Disease
Intervention: Other: Rhythmic Auditory Stimulation
Sponsor: University of North Carolina, Chapel Hill
Recruiting - Condition: Parkinson Disease
Intervention: Drug: APL-130277
Sponsor: Sunovion
Recruiting - Condition: Parkinson's Disease
Intervention: Device: Transcranial ExAblate
Sponsor: InSightec
Recruiting - Condition: Parkinson's Disease (PD)
Intervention: Drug: ABBV-951
Sponsor: AbbVie
Not yet recruiting - Condition: Parkinson's Disease (PD)
Intervention: Drug: ABT-SLV187
Sponsor: AbbVie
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Probiotic Agent; Drug: Placebo oral capsule
Sponsor: University of Malaya
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: University Hospital, Lille; France Parkinson Association
Recruiting - Condition: Parkinson Disease
Intervention: Drug: IRL790
Sponsors: Integrative Research Laboratories AB; The Clinical Trial Company
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Spinning Class; Behavioral: Yoga Class; Behavioral: Dance Class
Sponsors: Premier Health; Parkinson's Disease Foundation; Dartmouth-Hitchcock Medical Center
Recruiting - Condition: Parkinson's Disease, Idiopathic
Interventions: Drug: Methylphenidate; Other: Physical Therapy; Drug: Atomoxetine
Sponsor: Shnehal Patel
Recruiting - Condition: Parkinson's Disease (PD)
Intervention:
Sponsor: AbbVie
Recruiting - Condition: Parkinson's Disease (PD)
Intervention: Drug: ABBV-951
Sponsor: AbbVie
Recruiting - Condition: Parkinson's Disease
Intervention: Other: magnetic resonance imaging
Sponsor: Poitiers University Hospital
Recruiting - Condition: Parkinson Disease
Intervention: Other: no intervention
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Recruiting - Conditions: Parkinson Disease; Driving Impaired
Intervention: Device: Lane change assistance system
Sponsor: Western University, Canada
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: Active tDCS; Device: Sham tDCS
Sponsor: New York University School of Medicine
Recruiting - Condition: Parkinson Disease
Interventions: Device: ExAblate Pallidotomy; Device: Sham ExAblate Pallidotomy
Sponsor: InSightec
Recruiting - Conditions: Freezing of Gait; Parkinson Disease
Intervention: Device: EQUISTASI
Sponsors: ASST Gaetano Pini-CTO; Grisons Foundation for Parkinson's Disease; Policlinico San Matteo Pavia Fondazione IRCCS
Recruiting - Conditions: Parkinson Disease; Neurodegenerative Diseases
Interventions: Dietary Supplement: Nicotinamide Riboside; Other: Placebo
Sponsor: Haukeland University Hospital
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: PR Oxycodone; Drug: Levodopa; Drug: Oxycodone Placebo; Drug: Levodopa placebo
Sponsor: University Hospital, Toulouse
Recruiting - Conditions: Pain; Parkinson Disease
Interventions: Device: deep rTMS; Device: placebo deep rTMS
Sponsor: University of Sao Paulo
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: National Institute of Mental Health (NIMH)
Recruiting - Condition: Idiopathic Parkinson Disease
Interventions: Drug: Safinamide Methanesulfonate; Drug: Safinamide methanesulfonate matching placebo
Sponsor: Zambon SpA
Not yet recruiting - Conditions: Parkinson Disease; Executive Dysfunction
Intervention: Device: Computer-based cognitive training
Sponsor: Bispebjerg Hospital
Recruiting - Condition: Parkinsons Disease With Dementia
Interventions: Drug: High dose ANAVEX2-73; Drug: Mid dose ANAVEX2-73; Drug: Placebo oral capsule
Sponsors: Anavex Life Sciences Corp.; Anavex Germany GmbH
Recruiting - Conditions: Parkinson Disease; Rehabilitation
Interventions: Procedure: Stand-Up Paddle Rehabilitation; Procedure: Physiotherapy Rehabilitation
Sponsor: FLABEAU Olivier
Not yet recruiting - Condition: Oxidative Stress is an Important Cause of Parkinson's Disease
Intervention: Drug: Idebenone/placebo
Sponsors: Second Affiliated Hospital of Soochow University; Qilu Pharmaceutical Co., Ltd.
Not yet recruiting - Conditions: Oral Health; Parkinson Disease
Intervention: Behavioral: Delivery of oral hygiene advices
Sponsors: University Hospital, Bordeaux; Capionis; France Parkinson Association
Not yet recruiting - Condition: Parkinson's Disease (PD)
Interventions: Drug: ABT-SLV187; Drug: optimized antiparkinsonian treatment
Sponsor: AbbVie
Recruiting - Conditions: Parkinson Disease; Bone Loss
Intervention:
Sponsor: T.C. ORDU ÜNİVERSİTESİ
Not yet recruiting - Condition: Virtual Reality; Rehabilitation; Parkinson's Disease
Interventions: Device: Virtual reality-based interactive treadmill training; Device: Treadmill training without VR-based interaction
Sponsors: Seoul National University Hospital; Ministry of Trade, Industry & Energy(MOTIE, Korea)
Recruiting - Conditions: Depression; Parkinson Disease
Interventions: Drug: Nortriptyline; Drug: Escitalopram; Drug: Placebo
Sponsors: University College, London; London North West Healthcare NHS Trust; King's College London; University Hospital Plymouth NHS Trust; NHS Lothian
Not yet recruiting - Condition: Parkinsons Disease With Dementia
Intervention: Device: MR Guided Focused Ultrasound
Sponsor: InSightec
Recruiting - Conditions: Sialorrhea; Parkinson's Disease
Interventions: Drug: Glycopyrrolate; Drug: Placebo
Sponsor: Ottawa Hospital Research Institute
Recruiting - Conditions: Parkinson's Disease; Mild Cognitive Impairment
Interventions: Behavioral: cognitive training; Behavioral: active control cognitive training; Behavioral: memory strategy training
Sponsor: VA Office of Research and Development
Not yet recruiting - Conditions: Parkinson Disease; Gaucher Disease
Intervention:
Sponsor: Lysosomal and Rare Disorders Research and Treatment Center, Inc.
Recruiting - Conditions: Anxiety Disorders; Parkinson Disease
Interventions: Drug: rotigotine transdermal patch; Drug: placebo
Sponsors: Johns Hopkins University; National Institute on Aging (NIA)
Recruiting - Condition: Parkinson Disease Psychosis
Intervention: Other: Real-world, non-interventional
Sponsor: ACADIA Pharmaceuticals Inc.
Recruiting - Condition: Parkinson Disease Psychosis
Interventions: Drug: Saracatinib; Drug: Placebo Oral Tablet
Sponsors: King's College London; AstraZeneca; King's College Hospital NHS Trust
Not yet recruiting - Conditions: Parkinson's; Anosognosia
Intervention: Behavioral: Questionnaires
Sponsor: University of Birmingham
Recruiting - Conditions: Overactive Bladder; Parkinson Disease
Interventions: Drug: solifenacin; Behavioral: Pelvic floor muscle exercise-based behavioral therapy
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Parkinson Disease; Apathy
Intervention: Other: Starkstein scale of Apathy
Sponsor: University Hospital, Grenoble
Recruiting - Conditions: Parkinson's Disease; Mild Cognitive Impairment
Intervention: Device: MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)
Sponsor: VA Office of Research and Development
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: APL-130277; Drug: APO-go; Drug: Apokyn
Sponsor: Sunovion
Recruiting - Conditions: Parkinson Disease; Mild Cognitive Impairment
Interventions: Device: transcranial direct current stimulation; Device: Sham (for transcranial direct current stimulation)
Sponsor: Sanford Health
Recruiting - Conditions: Parkinson Disease; Movement Disorders
Intervention:
Sponsors: Oregon Health and Science University; Portland VA Medical Center
Recruiting - Conditions: Parkinson Disease; Gait Disorders, Neurologic
Interventions: Other: Treadmill + VR; Other: Treadmill
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Not yet recruiting - Conditions: Healthy; Parkinson Disease
Interventions: Drug: Lu AF82422; Drug: Placebo
Sponsor: H. Lundbeck A/S
Recruiting - Conditions: Exercise; Parkinson Disease
Intervention: Other: Exercise
Sponsor: Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Not yet recruiting - Condition: Parkinson Disease
Intervention: Diagnostic Test: Functional Activities Questionnaire
Sponsors: University Hospital Tuebingen; Sub-Investigator, Dr. Kathrin Brockmann, University Hospital of Tuebingen, Tuebingen, Germany; Advisory board, Prof. Dr. Thomas Gasser, University Hospital of Tuebingen, Tuebingen, Germany; Advisory board, Prof. Dr. Berg, Christian-Albrechts-University, Kiel, Germany
Recruiting - Condition: Parkinson's Disease
Interventions: Behavioral: CogSMART-PD; Behavioral: Supportive Care
Sponsor: VA Office of Research and Development
Recruiting - Condition: Parkinson Disease
Intervention: Other: Neuropsychological detailed tests with focus on social cognition
Sponsor: Hospices Civils de Lyon
Recruiting - Condition: Parkinson
Intervention: Device: Deep Brain Stimulation
Sponsor: Mustafa Kemal University
Recruiting - Conditions: Parkinson Disease; Mild Cognitive Impairment
Intervention: Device: transcranial direct current stimulation
Sponsor: University of Manitoba
Recruiting - Conditions: Idiopathic Parkinson's Disease; Parkinson Disease; Depression
Intervention: Device: Transcranial Direct Current Stimulation
Sponsor: Johns Hopkins University
Recruiting - Condition: Parkinson Disease
Interventions: Device: Serious game; Device: Placebo serious game
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Not yet recruiting - Conditions: Parkinson Disease; Dystonia
Intervention: Device: Summit RC+S
Sponsor: University of California, San Francisco
Not yet recruiting - Conditions: Parkinson Disease; Cognitive Impairment
Interventions: Behavioral: Working memory updating training; Behavioral: Placebo training
Sponsors: Umeå University; Karlstad University
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: treadmill training and overground gait training
Sponsor: National Taiwan University Hospital
Recruiting - Conditions: Parkinson's Disease; Visual Hallucinations
Intervention: Diagnostic Test: Optical Coherence Tomography
Sponsors: University Hospital, Clermont-Ferrand; Fondation de France
Not yet recruiting - Conditions: Cognitive Impairment; Parkinson Disease
Intervention: Behavioral: Cognitive Remediation
Sponsor: New York Institute of Technology
Recruiting - Conditions: Parkinson's Disease; Mpulse Control Disorders
Interventions: Drug: placebo; Drug: Clonidine
Sponsor: Hospices Civils de Lyon
Not yet recruiting - Condition: Parkinson Disease
Intervention: Other: Parkinson's disease nurse specialist care
Sponsors: Radboud University; ZonMw: The Netherlands Organisation for Health Research and Development; Zambon SpA
Recruiting - Conditions: Parkinson Disease; Motor Disorder
Interventions: Drug: BTRX-246040; Drug: Placebo
Sponsor: BlackThorn Therapeutics, Inc.
Recruiting - Conditions: Parkinson's Disease; Tremor
Interventions: Drug: CX-8998; Drug: Placebo
Sponsor: Cavion, Inc.
Not yet recruiting - Condition: Idiopathic Parkinson Disease
Intervention:
Sponsors: Neurocenter of Southern Switzerland; Parkinson Schweiz; Ente Ospedaliero Cantonale, Bellinzona; Penn State University
Recruiting - Conditions: Parkinson's Disease; Movement Disorders
Intervention:
Sponsor: Ottawa Hospital Research Institute
Recruiting - Conditions: Parkinson Disease; Parkinsonism
Intervention:
Sponsors: University College, London; European Commission; University of Luxembourg; University of Luebeck; Leiden University Medical Center
Recruiting - Conditions: Constipation; Parkinson Disease
Interventions: Drug: Active Investigational Treatment ENT-01; Drug: Placebo Treatment
Sponsor: Enterin Inc.
Recruiting - Conditions: Parkinson Disease; Cognitive Impairment
Intervention: Device: deep brain stimulation
Sponsor: University of California, Davis
Recruiting - Conditions: Parkinson Disease; Depression
Interventions: Biological: OnabotulinumtoxinA; Biological: Control
Sponsor: Johns Hopkins University
Recruiting - Conditions: Parkinson Disease; Parkinsonian Disorders
Intervention: Diagnostic Test: Level of alpha-synuclein
Sponsor: Centre Hospitalier Universitaire de Nīmes
Recruiting - Conditions: Parkinson's Disease; Mild Cognitive Impairment
Interventions: Device: TMS; Device: Sham-TMS
Sponsors: University of Calgary; Montreal Neurological Institute and Hospital; McGill University; Canadian Institutes of Health Research (CIHR)
Recruiting - Condition: Treatment of Depression in Adults With Parkinson's Disease (PD)
Intervention: Drug: Pimavanserin
Sponsor: ACADIA Pharmaceuticals Inc.
Recruiting - Condition: Parkinson Disease
Intervention: Device: Intracerebral Infusion of Autologous Cerebral Spinal Fluid
Sponsor: Jeff Elias, MD
Recruiting - Conditions: Parkinson's Disease; Constipation
Intervention: Procedure: OMM treatment
Sponsor: New York Institute of Technology
Recruiting - Conditions: Parkinson's Disease; Mild Cognitive Impairment
Intervention:
Sponsors: University of Calgary; Canadian Institutes of Health Research (CIHR); Natural Sciences and Engineering Research Council, Canada; Montreal Neurological Institute and Hospital; McGill University
Recruiting - Conditions: Parkinson Disease; Dementia
Interventions: Device: Vercise deep brain stimulation; Procedure: subthalamic nucleus (STN) stimulation; Procedure: NBM stimulation; Procedure: sham stimulation
Sponsor: Wuerzburg University Hospital
Recruiting - Conditions: Urinary Bladder, Overactive; Parkinson Disease
Interventions: Drug: Fesoterodine; Drug: Placebo
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital
Recruiting - Conditions: Parkinson Disease; Parkinson's Syndrome
Intervention: Procedure: Self-rehabilitation by digital support
Sponsors: Pôle Saint Hélier; Réseau Parkinson Bretagne; Rennes University Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Drug: K0706; Drug: Placebo
Sponsor: Sun Pharma Advanced Research Company Limited
Recruiting - Condition: Parkinson Disease
Intervention: Device: Dynamic Standing Table
Sponsor: University of Michigan
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Adapted Tango Dancing; Behavioral: Behavioral Control (BC) Condition
Sponsor: VA Office of Research and Development
Recruiting - Condition: Parkinson Disease
Intervention: Device: Detection of freezing
Sponsor: University Hospital, Montpellier
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Xiangya Hospital of Central South University
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Xiangya Hospital of Central South University
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Xiangya Hospital of Central South University
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Xiangya Hospital of Central South University
Recruiting - Condition: Parkinson Disease
Intervention: Device: Bilateral deep brain stimulation of the subthalamic nucleus
Sponsors: Chen Ling; Prince of Wales Hospital, Shatin, Hong Kong; Shenzhen Second People's Hospital
Recruiting - Conditions: Parkinson's Disease; Multiple System Atrophy
Intervention: Device: Transcranial direct current stimulation
Sponsors: China Medical University Hospital; Ministry of Science and Technology, Taiwan
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Xiangya Hospital of Central South University
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Vanderbilt University Medical Center
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Safinamide
Sponsor: IRCCS San Raffaele
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Capsaicin; Device: Resistive respiratory loads; Other: Event-related evoked potential using electroencephalography (EEG).; Procedure: Fluoroscopic swallow evaluation
Sponsors: University of Florida; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - Conditions: Parkinson Disease; Virtual Reality Therapy; Functional Magnetic Resonance Imaging
Interventions: Behavioral: Virtual Reality; Behavioral: Exercise Therapy; Drug: Pharmacological Treatment
Sponsor: Farzin Hajebrahimi, PT, MSc
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: University of Rochester; Biogen
Not yet recruiting - Conditions: Parkinson Disease; Impaired Cognition; Alteration in Cognition
Interventions: Behavioral: Online cognitive training 1; Behavioral: Online cognitive training 2
Sponsors: VU University Medical Center; Dutch Parkinson Patient Association
Recruiting - Condition: Parkinson Disease
Interventions: Device: Adaptive DBS; Device: Conventional DBS
Sponsors: St. George's Hospital, London; University of Oxford
Not yet recruiting - Condition: Parkinson's Disease
Interventions: Other: Treadmill training with auditory cues; Other: Treadmill training without auditory cues
Sponsor: National Taiwan University Hospital
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Hospital Universitari Vall d'Hebron Research Institute
Recruiting - Condition: Parkinson Disease
Interventions: Drug: 009-1; Drug: active comparator; Drug: 009-0; Drug: 009-2; Drug: 009-3; Drug: 009-4; Drug: 009-5
Sponsor: Alexza Pharmaceuticals, Inc.
Recruiting - Condition: Parkinson's Disease
Intervention: Other: Diffusion Weighted Imaging (DWI)
Sponsor: University of Alabama at Birmingham
Recruiting - Defining a PD-specific Breath Fingerprint of Underlying Inflammatory and Neurodegenerative ProcessesCondition: Parkinson's Disease
Interventions: Other: Blood Sample Collection; Other: Breath Sample Collection
Sponsors: Emory University; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Conditions: Parkinson Disease; Intestinal Bacteria Flora Disturbance; Dietary Modification
Interventions: Dietary Supplement: Resistant maltodextrin; Dietary Supplement: maltodextrin
Sponsors: Northwestern University; University of Illinois at Chicago
Recruiting - Conditions: Dyskinesia, Drug-Induced; Parkinson Disease
Intervention: Device: Repetitive transcranial magnetic stimulation
Sponsors: Danish Research Centre for Magnetic Resonance; University Hospital Bispebjerg and Frederiksberg; Danish Movement Disorder Society (DANMODIS); Danish Parkinson Association
Recruiting - Condition: Parkinson Disease
Interventions: Other: Rock Steady Boxing; Other: PD SAFEx
Sponsor: Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Levodopa dispersible; Drug: Levodopa
Sponsors: Seoul National University Hospital; SMG-SNU Boramae Medical Center; Samsung Medical Center
Recruiting - Conditions: REM Sleep Behavior Disorder; Pre-motor Parkinson Disease; Symptomatic Parkinson Disease
Intervention: Drug: Carvedilol
Sponsor: Michele Tagliati, MD
Not yet recruiting - Conditions: Parkinson Disease; Healthy
Interventions: Other: Parkinson's disease patients; Other: No drug
Sponsor: Universidade Federal de Pernambuco
Recruiting - Condition: Parkinson's Disease
Interventions: Device: Transcranial Direct Current Stimulation (tDCS); Other: locomotor training; Other: sham-tDCS
Sponsor: University of Miami
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: Massachusetts General Hospital; Northwestern University; Sage Bionetworks; University of Rochester; National Institute of Neurological Disorders and Stroke (NINDS); Michael J. Fox Foundation for Parkinson's Research; The Parkinson Study Group
Recruiting - Conditions: Parkinson's Disease and Parkinsonism; Postural Kyphosis
Intervention: Device: ambulatory use of the Upright device
Sponsor: Tel-Aviv Sourasky Medical Center
Recruiting - Condition: Parkinson's Disease (PD)
Intervention:
Sponsor: AbbVie
Recruiting - Condition: Parkinson's Disease
Interventions: Device: voltage adjustment only; Device: Combined parameters adjustment
Sponsors: Chen Ling; Prince of Wales Hospital, Shatin, Hong Kong; Shenzhen Second People's Hospital
Recruiting - Conditions: Dexmedetomidine; Deep Brain Stimulation; Parkinson Disease
Intervention: Drug: Dexmedetomidine
Sponsor: Clinica Universidad de Navarra, Universidad de Navarra
Recruiting - Conditions: Parkinson Disease; MSA - Multiple System Atrophy
Intervention: Procedure: voice recordings
Sponsors: University Hospital, Bordeaux; Institut National de Recherche en Informatique et en Automatique
Recruiting - Condition: Idiopathic Parkinson Disease
Intervention: Combination Product: CTC-413
Sponsor: Chase Therapeutics Corporation
Not yet recruiting - Conditions: Parkinson Disease; Orthostatic Hypotension
Intervention: Other: Abdominal Strengthening Exercise
Sponsor: Faizan Ahmed
Recruiting - Conditions: Parkinson's Disease; Obstructive Sleep Apnea
Interventions: Drug: Sinemet CR; Drug: Placebo oral capsule
Sponsors: McGill University Health Center; Weston Brain Institute
Recruiting - Conditions: Parkinson's Disease; Dysphagia; Dystussia
Interventions: Device: EMST; Behavioral: smTAP
Sponsors: Teachers College, Columbia University; Michael J. Fox Foundation for Parkinson's Research; University of Florida
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: CBT group
Sponsor: New York Institute of Technology
Recruiting - Condition: Parkinson's Disease
Intervention: Device: transcranial direct current stimulation (tDCS)
Sponsor: Inje University
Recruiting - Clinical Characteristics of Parkinson's Disease Subjects With Severe Hypertension During Motor OFFs.Conditions: Parkinson Disease; Hypertension; Antiparkinsonism Drugs Causing Adverse Effects in Therapeutic Use
Intervention: Other: No Intervention
Sponsor: Oregon Health and Science University
Recruiting - Conditions: Parkinson's Disease; Gastroparesis; Constipation
Interventions: Drug: RQ-00000010; Drug: Placebo
Sponsors: Virginia Commonwealth University; Michael J. Fox Foundation for Parkinson's Research; RaQualia Pharma Inc.
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Apomorphine; Drug: Dopaminergic Agonist + Apomorphine
Sponsor: Rennes University Hospital
Not yet recruiting - Conditions: Parkinson's Disease; Drug-induced Parkinsonism
Intervention: Behavioral: Exercise
Sponsors: VA Office of Research and Development; University of Pennsylvania
Recruiting - Condition: Parkinson Disease
Intervention: Device: The LFP Beta aDBS System
Sponsor: MedtronicNeuro
Recruiting - Conditions: Parkinson Disease; Freezing of Gait
Intervention: Behavioral: Split-Belt Treadmill Training
Sponsors: KU Leuven; University of Kiel
Recruiting - Conditions: Parkinson Disease; Dementia; Mild Cognitive Impairment
Interventions: Other: Exoskeleton exercise; Other: Standard exercise; Other: No treatment
Sponsors: Baycrest; Centre for Aging and Brain Health Innovation; University of New Brunswick
Recruiting - Conditions: Parkinson Disease; Movement Disorders; Neuro-Degenerative Disease
Interventions: Other: Golf Instruction; Other: Tai Chi Class
Sponsor: Massachusetts General Hospital
Recruiting - Conditions: Parkinson Disease; REM Sleep Behavior Disorder; Healthy
Intervention: Drug: (11C)PE2I
Sponsors: Weill Medical College of Cornell University; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Stroke, Acute; Parkinson Disease; Femur Fracture
Interventions: Other: Novel locomotion treatment: curved-walking training; Other: Standard locomotion treatment: straight-walking training; Other: Standard physical therapy
Sponsors: Istituti Clinici Scientifici Maugeri SpA; DEIB, Politecnico di Milano, Italy
Recruiting - Condition: Parkinson Disease
Intervention: Procedure: Biofluid samplings
Sponsors: Michael J. Fox Foundation for Parkinson's Research; University Health Network, Toronto; Indiana University; Clinical Trials Coordination Center
Recruiting - Conditions: Parkinson's Disease; Dysphagia
Interventions: Device: [standard STN]; Device: [STN+SNr]; Behavioral: Swallowing therapy
Sponsors: University Hospital Tuebingen; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Conditions: Alzheimer's Disease; Parkinson's Disease; Frontotemporal Lobar Degeneration
Intervention: Behavioral: Observational Study
Sponsor: University Health Network, Toronto
Recruiting - Conditions: Parkinson; Parkinson Disease; Genetic Predisposition; GBA Gene Mutation; Cognitive Decline
Intervention: Other: cognitive assessments
Sponsors: Rush University Medical Center; National Institutes of Health (NIH); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Aging; Parkinson Disease
Interventions: Device: Vielight NeuroGamma system; Device: Sham Vielight NeuroGamma system; Device: Vielight 810 intranasal stand alone unit; Device: Sham Vielight 810 intranasal stand alone unit
Sponsors: University of Florida; McKnight Brain Research Foundation; University of Arizona
Not yet recruiting - Conditions: Parkinson's Disease; Falls; Balance; Urinary Bladder Diseases
Intervention:
Sponsor: T.C. ORDU ÜNİVERSİTESİ
Recruiting - Condition: Parkinson Disease
Intervention: Procedure: Lumbar Puncture
Sponsors: Michael J. Fox Foundation for Parkinson's Research; University Health Network, Toronto; Indiana University; Clinical Trials Coordination Center
Not yet recruiting - Condition: Parkinson's Disease
Intervention: Device: Deep Brain Stimulation (DBS)
Sponsor: Boston Scientific Corporation
Recruiting - Condition: Parkinson's Disease
Interventions: Other: body-scan meditation; Diagnostic Test: Psychological evaluation
Sponsor: University Hospital, Bordeaux
Recruiting - Conditions: Transcranial Magnetic Stimulation; Functional Magnetic Resonance Imaging; Parkinson Disease
Intervention: Other: transcranial magnetic stimulation
Sponsor: Anhui Medical University
Recruiting - Conditions: Alzheimer's Disease; Lewy Body Dementia; Parkinson's Disease
Interventions: Radiation: DaTscan; Radiation: F18-AV-45; Radiation: FDG-PET; Genetic: APOE genotype; Procedure: Polysomnogram; Behavioral: Clinical Assessment
Sponsors: Douglas Scharre; Avid Radiopharmaceuticals; Mangurian Foundation
Recruiting - Condition: Parkinson's Disease
Intervention: Behavioral: Exercise and Education for Parkinson's Disease
Sponsors: Oregon Health and Science University; National Institute on Aging (NIA)
Recruiting - Conditions: Parkinson's Disease; Stroke
Interventions: Other: Dual-task training; Other: Treadmill training
Sponsor: National Yang Ming University
Recruiting - RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's DiseaseConditions: Essential Tremor; Parkinson Disease
Intervention: Device: Unframed Virtual Cone
Sponsor: University of Alabama at Birmingham
Recruiting - Conditions: Parkinson Disease; Dyspepsia
Interventions: Drug: DA-9701; Drug: DA-9701 placebo
Sponsors: Seoul National University Hospital; Samsung Medical Center; Korea University Guro Hospital; Hanyang University; Seoul Veterans Hospital; SMG-SNU Boramae Medical Center
Recruiting - Conditions: Parkinson Disease; Surgery; Respiration; Decreased; Muscle Weakness
Intervention: Device: MIP and MEP
Sponsor: Mustafa Kemal University
Recruiting - Condition: Parkinson Disease
Intervention: Drug: [11C]PXT012253
Sponsor: H. Lundbeck A/S
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Ongentys; Drug: BIA 9-1067 (test)
Sponsor: Bial - Portela C S.A.
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: STN alone; Device: GPi alone; Device: STN + GPi; Device: Closed-loop stimulation
Sponsors: Dennis Turner, M.D.; National Institutes of Health (NIH); Duke University; National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - Condition: Parkinson Disease
Intervention: Procedure: Personalized DBS adjustments
Sponsor: Darlene Floden
Recruiting - Condition: Parkinson Disease
Intervention: Procedure: Transcranial direct current stimulation
Sponsor: Universidade Federal do Piauí
Recruiting - Condition: Parkinson Disease
Interventions: Drug: LY03003; Drug: Neupro 4Mg/24Hr Transdermal Patch
Sponsor: Luye Pharma Group Ltd.
Recruiting - Conditions: Gait Disorders, Neurologic; Parkinson Disease
Intervention: Device: Carbon Fiber Ankle Foot Orthosis (AFO)
Sponsors: University of Texas Southwestern Medical Center; American Orthotic and Prosthetic Association
Recruiting - Conditions: Parkinson Disease; Neurogenic Orthostatic Hypotension
Interventions: Drug: Droxidopa; Drug: Placebo
Sponsors: William Ondo, MD; Lundbeck LLC
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: KW-6356 Low Dose; Drug: KW-6356 Middle Dose; Drug: KW-6356 High Dose; Drug: KW-6356 X Dose; Drug: KW-6356 Y Dose; Drug: Placebo
Sponsor: Kyowa Hakko Kirin Co., Ltd
Recruiting - Condition: Parkinson Disease
Interventions: Device: biphasic stimulation; Device: standard stimulation; Device: Uniform distribution; Device: Poisson distribution; Device: Recordings of LFP oscillations
Sponsor: Colette Boex
Recruiting - Condition: Parkinson's Disease
Intervention: Drug: Rasagiline
Sponsor: Takeda
Recruiting - Condition: Parkinson's Disease
Intervention: Other: Detailed motor testing, including FoG, in PD subjects
Sponsors: VA Office of Research and Development; University of Michigan
Recruiting - Condition: Parkinson's Disease
Intervention: Drug: Exenatide
Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Idiopathic Parkinson's Disease
Interventions: Drug: PD patients H&Y=1.5-2 Medications ON; Drug: PD patients H&Y=1.5-2 Medications OFF; Behavioral: Healthy age-matched controls; Drug: PD patients H&Y=3 Medications OFF; Drug: PD patients H&Y=3 Medications ON
Sponsor: Giovanni Mirabella
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: Vercise Deep Brain Stimulation System
Sponsor: Boston Scientific Corporation
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: MEDI1341; Drug: Placebo
Sponsors: AstraZeneca; Covance; MMS Holdings, Inc; Catalent
Recruiting - Condition: Parkinson Disease
Intervention: Device: SJM Infinity
Sponsor: Abbott Medical Devices
Recruiting - Condition: Parkinson Disease
Intervention: Device: Algorithm based programming using Kinesia-based assessment
Sponsors: Great Lakes NeuroTechnologies Inc.; University of Cincinnati; Ohio State University; Wake Forest University
Recruiting - Condition: Parkinson's Disease
Interventions: Device: iPad-Based Clinical Support Care; Other: Standard Clinical Care
Sponsors: University of Utah; University of Florida; National Institute of Nursing Research (NINR); Wake Forest University Health Sciences; Baylor College of Medicine; NYU; University of California, San Francisco
Recruiting - Condition: Parkinson's Disease (PD)
Intervention:
Sponsor: AbbVie
Recruiting - Conditions: Impulse Control Disorder; Parkinson
Intervention: Biological: Variation of behaviors of Parkinson's disease
Sponsor: Centre Hospitalier Universitaire, Amiens
Recruiting - Conditions: Acupuncture; Parkinson's Disease; Sleep Disorders; Neuroimaging
Intervention: Device: Sterile acupuncture needles for single use
Sponsor: Tsinghua University
Not yet recruiting - Condition: Parkinson Disease, Essential Tremors and Dystonia
Intervention: Device: Deep Brain Stimulation
Sponsor: Assiut University
Not yet recruiting - Condition: Parkinson's Disease (PD)
Intervention: Device: New Programming Paradigm
Sponsor: Boston Scientific Corporation
Recruiting - Condition: Parkinson Disease
Intervention: Device: [18F]T807 (also known as 18F-AV- 1451)
Sponsors: University of Pennsylvania; Avid Radiopharmaceuticals
Recruiting - Conditions: Parkinson Disease; Movement Disorders; Neurodegenerative Diseases; Nervous System Diseases; Brain Diseases
Interventions: Drug: Cerebral Dopamine Neurotrophic Factor; Device: Renishaw Drug Delivery System
Sponsors: Herantis Pharma Plc.; Renishaw plc.
Recruiting - Condition: Parkinson Disease With Freezing of Gait
Intervention: Radiation: transcranial magnetic stimulation
Sponsor: Medical University of South Carolina
Recruiting - Conditions: Parkinson Disease; Movement Disorders; Neuro-Degenerative Disease; Nervous System Diseases; Brain Diseases
Interventions: Drug: Cerebral Dopamine Neurotrophic Factor; Device: Renishaw Drug Delivery System
Sponsors: Herantis Pharma Plc.; Renishaw plc.
Recruiting - Conditions: Central Nervous System Disease; Basal Ganglia Disease; Movement Disorders; Neurodegenerative Disorders; Parkinson Disease
Interventions: Procedure: Deep brain stimulation (DBS) of Globus Pallidus internus (GPi) and Best medical treatment (BMT); Procedure: Best medical treatment
Sponsors: University Hospital Inselspital, Berne; Boston Scientific Corporation
Recruiting - Condition: Parkinson's Disease Patients Undergoing Deep Brain Stimulation (DBS) Surgery
Intervention: Other: Measuring electrical signals from the brain
Sponsors: University of California, Los Angeles; The Cleveland Clinic; University of California, San Francisco; University of California, San Diego; California Institute of Technology; Cedars-Sinai Medical Center
Recruiting - Conditions: Primary Parkinsonism; Rehabilitation; Kinematics; Gait Disorders, Neurologic
Interventions: Other: Mental and Physical Practice; Other: Physical Practice
Sponsor: Universidade Federal do Rio Grande do Norte
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Healthy Volunteers
Intervention: Drug: [18F]MNI-1126
Sponsor: Invicro
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease
Intervention: Behavioral: Cognitive tests
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Observation
Intervention:
Sponsors: Ain Shams University; Al-Azhar University
Recruiting - Conditions: Essential Tremor; Multiple System Atrophy; Corticobasal Degeneration; Supranuclear Palsy, Progressive; Parkinson Disease
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Conditions: Parkinson Disease; Multiple System Atrophy; REM Sleep Behavior Disorder; Pure Autonomic Failure; Dementia With Lewy Bodies
Intervention:
Sponsors: New York University School of Medicine; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Conditions: Parkinson Disease; Gait Disorders, Neurologic; Treadmill
Interventions: Behavioral: musical treadmill; Behavioral: Traditional treadmill
Sponsor: Ospedale Generale Di Zona Moriggia-Pelascini
Recruiting - Conditions: Parkinson's Disease; Generalized Anxiety Disorder; Social Phobia
Interventions: Behavioral: Cognitive Behavioural Therapy (CBT); Other: Clinical monitoring
Sponsors: Maastricht University Medical Center; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Conditions: Parkinson Disease; Parkinsonism; Lewy Body Disease; Supranuclear Palsy, Progressive; Parkinsonism Vascular; Multiple System Atrophy; Corticobasal Degeneration
Intervention: Behavioral: Palliative Care
Sponsors: University of Colorado, Denver; National Institute of Nursing Research (NINR); University of California, San Francisco
Recruiting - Condition: REM Sleep Behavior Disorder
Intervention: Diagnostic Test: Colonoscopy
Sponsor: Chinese University of Hong Kong
Not yet recruiting - Conditions: Parkinson Disease; Falls Patient
Interventions: Drug: Droxidopa; Other: Placebo
Sponsors: St. Joseph's Hospital and Medical Center, Phoenix; H. Lundbeck A/S; Arizona State University
Recruiting - Conditions: Parkinson Disease; Ataxia
Interventions: Behavioral: Auditory; Behavioral: Gestures
Sponsors: Herbert H. Lehman College, City University of New York; University of Utah
Recruiting - Condition: Parkinsonian Disorders
Interventions: Other: V1: HGPO + meal and V2: placebo + meal; Other: V1: placebo 75mg + meal and V2: HGPO 75mg + meal
Sponsors: University Hospital, Toulouse; Ministry of Health, France
Recruiting - Conditions: Essential Tremor; Parkinson's Disease
Intervention: Device: Clinician programmer electrode screening mode tool
Sponsor: Abbott Medical Devices
Not yet recruiting - Conditions: Parkinson Disease; Cognitive Impairment
Intervention:
Sponsor: University of Washington
Recruiting - Condition: Parkinson
Intervention: Device: DBS
Sponsors: Abbott Medical Devices; Baylor College of Medicine; University of Houston
Recruiting - Conditions: Parkinson Disease (PD); Paralysis; Supranuclear
Intervention: Other: 3D gait analysis
Sponsor: IRCCS San Raffaele
Recruiting - Conditions: Secondary Parkinsonism; Parkinson's Disease
Intervention: Other: no intervention
Sponsor: Corporal Michael J. Crescenz VA Medical Center
Recruiting - Conditions: Parkinson Disease; Essential Tremor
Intervention: Other: Data Capture
Sponsor: Westfälische Wilhelms-Universität Münster
Recruiting - Conditions: Parkinson Disease; REM Behavior Disorder
Intervention: Other: Sleep, PD and DBS
Sponsor: University of Colorado, Denver
Recruiting - Conditions: Parkinson Disease; Restless Leg Syndrome
Intervention: Behavioral: Diary (for reporting all impulse control disorders especially compulsive eating disorders)
Sponsor: University Hospital, Clermont-Ferrand
Not yet recruiting - Conditions: Essential Tremor; Parkinson's Disease
Interventions: Procedure: Deep brain stimulation implantation surgery; Device: Ad-Tech Medical Instrumentation Corp. device; Device: FHC Guideline 4000+ system
Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Amyotrophic Lateral Sclerosis; Parkinson Disease
Intervention: Behavioral: Phonetic complexity effects on speech motor performance
Sponsors: University of Missouri-Columbia; National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - Conditions: Parkinson Disease; Dystonia; Essential Tremor
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Parkinson Disease; Multiple Sclerosis; Trauma, Brain
Intervention:
Sponsor: T.C. ORDU ÜNİVERSİTESİ
Not yet recruiting - Conditions: Parkinson Disease; Essential Tremor; Dystonia
Intervention: Device: Deep Brain Stimulation
Sponsor: Boston Scientific Corporation
Not yet recruiting - Condition: TMS Protocols in the Treatment of PD
Intervention: Device: repetitive transcranial magnetic stimulation(rTMS)
Sponsor: Guangdong General Hospital
Not yet recruiting - Conditions: Parkinson's Disease; Essential Tremor; Dystonia
Intervention: Procedure: Deep Brain Stimulation
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Rapid Eye Movement Sleep Behavior Disorder
Intervention:
Sponsor: The University of Texas Health Science Center, Houston
Recruiting - Conditions: Parkinson Disease; Tremor, Essential; Dystonia, Primary
Intervention: Procedure: Hypnosis
Sponsor: University Hospital, Geneva
Recruiting - Conditions: Essential Tremor; Parkinson Disease; Dystonia
Interventions: Device: Active biphasic pulse stimulation---Home Settings; Device: Active biphasic pulse stimulation---VIN Biphasic; Device: Active biphasic pulse stimulation---Stimulator Off
Sponsors: University of Florida; National Institutes of Health (NIH)
Not yet recruiting - Conditions: Functional Movement Disorder; Parkinson Disease; Dystonic Disorders
Intervention: Other: Self-questionnaire YSQ-S3 (Young Schema Questionnaire)
Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting - Conditions: Neurogenic Bladder; Multiple Sclerosis; Parkinson Disease; Voiding Dysfunction
Intervention: Device: Transcranial Rotating Permanent Magnet Stimulator (TRPMS)
Sponsors: Rose Khavari, M.D.; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - Conditions: Subjective Cognitive Impairment; Mild Cognitive Impairment; Parkinson Disease; Healthy Volunteers
Interventions: Behavioral: exercise; Dietary Supplement: carnosine supplementation; Behavioral: stretching; Dietary Supplement: supplementation with placebo
Sponsors: Slovak Academy of Sciences; Comenius University; University Hospital Bratislava; National Cheng Kung University
Recruiting - Conditions: Parkinson Disease; Multiple System Atrophy; Progressive Supranuclear Palsy
Interventions: Drug: Droxidopa; Drug: Placebo Oral Tablet
Sponsors: Loma Linda University; H. Lundbeck A/S
Not yet recruiting - Conditions: Li-Fraumeni Syndrome; Parkinson's Disease; Atherosclerosis; Cardiovascular Capacity
Intervention:
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - Conditions: Essential Tremor; Parkinson's Disease; Movement Disorders; Neuropathic Pain
Intervention:
Sponsor: InSightec
Recruiting - Conditions: Tremor; Essential Tremor; Parkinson Disease; Radiosurgery; Quality of Life
Intervention: Other: Questionnaires / Observational Assessments
Sponsor: Vanderbilt University Medical Center
Recruiting - Conditions: Parkinson's Disease; Essential Tremor; Dystonia; Obsessive Compulsive Disorder
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Conditions: Alzheimer Dementia; Dementia, Vascular; Dementia, Lewy Body; Dementia Parkinson's Disease
Intervention: Behavioral: Resource oriented music therapy
Sponsors: University of Bergen; NKS Olaviken Alderspsykiatriske sykehus
Recruiting - Conditions: Multiple Sclerosis; Parkinson Disease; Amyotrophic Lateral Sclerosis; Alzheimer Disease
Intervention: Procedure: lumbar puncture
Sponsors: Neuromed IRCCS; IRCCS Multimedica
Recruiting - Conditions: Apathy; Frontotemporal Dementia; Parkinson Disease; Depressive Symptoms
Interventions: Behavioral: ECOCAPTURE; Behavioral: Cognitive and Behavioral experimental tasks; Diagnostic Test: Neuropsychological assessment; Behavioral: ICM_APATHY_TASKS; Other: MRI; Biological: Neurohormonal mechanisms
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - Conditions: Healthy Volunteer; Alzheimer Disease; Frontotemporal Dementia; Parkinson Disease
Intervention: Drug: [18F]PI-2620
Sponsors: Asan Medical Center; Korea Health Industry Development Institute
Recruiting - Conditions: Parkinson Disease; Dystonia; Depression; Spinal Stenosis; Spinal Diseases
Intervention: Diagnostic Test: MRI of the spine
Sponsor: University Health Network, Toronto
Not yet recruiting - Conditions: Parkinson Disease; Dystonia; Tremors; Obsessive Compulsive Disorder; Depression
Intervention: Other: No intervention
Sponsor: Ohio State University
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Vascular Cognitive Impairment; Parkinson's Disease; Lewy Body Disease
Intervention: Other: Flutemetamol PET scan
Sponsors: Sunnybrook Health Sciences Centre; Brain Canada; Weston Brain Institute; GE Healthcare; University Health Network, Toronto; Centre for Addiction and Mental Health; Baycrest; St. Michael's Hospital, Toronto; Kensington Eye Institute
Recruiting - Conditions: Parkinson's Disease; Movement Disorders; Deep Brain Stimulation; Dystonia; Essential Tremor
Intervention: Other: Deep Brain Stimulation Management
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Age-related Mobility Decline
Interventions: Behavioral: Dual-Belt Exercise; Behavioral: Treadmill Exercise; Other: Usual Care; Device: Dual-Belt Treadmill
Sponsors: University of Florida; National Institute on Aging (NIA)
Recruiting - Conditions: Aging; Parkinson Disease; Stroke; Dementia; Diagnoses Disease; Cognitive Impairment; Postural; Defect
Intervention: Diagnostic Test: Beam test to predict falls
Sponsors: University Medical Center Groningen; Dokkyo Medical University; University of Potsdam; Somogy Megyei Kaposi Mór Teaching Hospital; University of Sao Paulo
Not yet recruiting - Conditions: Amyotrophic Lateral Sclerosis (ALS); Myasthenia Gravis; Myopathies; Stroke; Parkinson's Disease
Intervention:
Sponsor: Beth Israel Deaconess Medical Center
Recruiting - Conditions: Anomia; Stroke; Aphasia; Parkinson Disease; Multiple Sclerosis
Interventions: Behavioral: Semantic feature analysis; Behavioral: Comprehension training
Sponsors: Göteborg University; The Swedish Research Council; Swedish Council for Working Life and Social Research
Recruiting - Conditions: Congenital Hyperinsulinism; Neuroblastoma; Neuroendocrine Tumors; Parkinson Disease; Brain Glioma
Intervention: Drug: 18F-DOPA
Sponsors: University of Alberta; Alberta Health Services
Recruiting - Conditions: Schizophrenia; Autism Spectrum Disorder; Bipolar Disorder; Depression; Parkinson Disease
Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS); Device: Sham Repetitive Transcranial Magnetic Stimulation (rTMS)
Sponsor: Krystal Parker
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Frontal Dementia; Huntington Disease; Traumatic Brain Injury; Stroke
Intervention: Behavioral: social cognition
Sponsor: Centre Hospitalier Universitaire, Amiens
Recruiting - Conditions: Autonomic Failure; Pure Autonomic Failure; Multiple System Atrophy; Parkinson Disease; Orthostatic Hypotension
Interventions: Drug: Droxidopa; Drug: Midodrine; Drug: Placebo
Sponsor: Vanderbilt University Medical Center
Recruiting - Conditions: REM Sleep Behavior Disorder; Parkinson Disease; Lewy Body Disease; Dementia With Lewy Bodies; Multiple System Atrophy; REM Sleep Parasomnias
Intervention:
Sponsors: Washington University School of Medicine; Mayo Clinic; University of Minnesota - Clinical and Translational Science Institute; University of California, Los Angeles; McGill University; Emory University; Massachusetts General Hospital; National Institute on Aging (NIA)
Recruiting - Conditions: Sporadic Dystonia; Dystonia, Familial; Parkinson Disease, Juvenile; Neurodegeneration With Brain Iron Accumulation 5; Mitochondrial Diseases
Interventions: Diagnostic Test: 3Tesla MRI; Behavioral: Burke-Fahn-Marsden Dystonia Rating scale; Behavioral: MDS-United Parkinsons Disease Rating Scale, Part III; Behavioral: Beck Depression Inventory; Behavioral: MoCA: Montreal Cognitive Assessment:
Sponsor: University College, London
Not yet recruiting - Conditions: Progressive Supranuclear Palsy; Dementia With Lewy Bodies; Multiple System Atrophy; Corticobasal Syndrome; Atypical Parkinson Disease
Interventions: Behavioral: Home Visit Program; Behavioral: Usual Care/Online Survey
Sponsor: Rush University Medical Center
Recruiting - Conditions: Chronic Autonomic Failure; Parkinson Disease With Orthostatic Hypotension; Dementia With Lewy Bodies; Orthostatic Hypotension; Multiple System Atrophy; Iatrogenic Chronic Autonomic Failure
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Parkinson's Disease; Parkinsonian Disorders; Atypical Parkinson Disease; Progressive Supranuclear Palsy; Multiple System Atrophy; Corticobasal Degeneration; Gait, Frontal
Interventions: Drug: Anti-Parkinson medication; Device: Deep Brain Stimulation
Sponsor: Beth Israel Deaconess Medical Center
Recruiting - Conditions: Dementia; Alzheimer Disease; Parkinson Disease; Lewy Body Disease; Parkinson-Dementia Syndrome; Frontotemporal Degeneration; Semantic Dementia; Progressive Nonfluent Aphasia; Progressive Supranuclear Palsy; Corticobasal Degeneration; Multiple System Atrophy; Mild Cognitive Impairment
Interventions: Diagnostic Test: Flutemetamol F18 Injection; Diagnostic Test: [18F]-RO6958948; Diagnostic Test: Elecsys (Roche) Abeta42, Ttau and Ptau; Diagnostic Test: Lumipulse (Fujirebio) Abeta42, Ttau and Ptau
Sponsors: Skane University Hospital; Lund University
Recruiting - Conditions: Ataxia; Dystonia; Parkinson's Disease; Amyotrophic Lateral Sclerosis; Corticobasal Degeneration; Multiple System Atrophy; Alzheimer's Disease; Lewy Body Dementia; Parkinson Disease-Dementia; Dentatorubral-pallidoluysian Atrophy; Creutzfeldt-Jakob Disease and Fatal Familial Insomnia; Fragile X-associated Tremor/Ataxia Syndrome; Krabbe's Disease; Niemann-Pick Disease, Type C; Neuronal Ceroid Lipofuscinosis
Intervention:
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: the Elderly
Intervention: Behavioral: tests
Sponsor: University Hospital, Strasbourg, France
Recruiting - Conditions: Alzheimer Disease (AD); Frontotemporal Lobar Degeneration; Dementia With Lewy Bodies (DLB); Parkinson Disease Dementia (PDD); Progressive Supranuclear Palsy (PSP); Corticobasal Degeneration (CBD)
Intervention:
Sponsors: Amoneta Diagnostics SAS; European Commission; Firalis SA; University Hospital, Strasbourg; Centre Hospitalier Universitaire Vaudois; IRCCS Centro San Giovanni di Dio Fatebenefratelli; Hôpitaux Civils de Colmar; Istanbul University; Assistance Publique - Hôpitaux de Paris; University Hospital, Lille; University Hospital, Geneva; Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Erasme University Hospital; University Hospital, Montpellier; Centre Hospitalier Universitaire de Besancon; Centre Hospitalier Universitaire de Nice
Recruiting - Conditions: Raynaud Disease; Raynaud Phenomenon; Hand and Arm Vibration Syndrome; Diabetes Mellitus; Parkinson Disease; Glaucoma; Autonomic Neuropathy; Autonomic Imbalance
Interventions: Diagnostic Test: Examination of vibration perception threshold in fingertips; Diagnostic Test: Ewing's tests; Diagnostic Test: Tilt table test; Diagnostic Test: Thermography; Diagnostic Test: 123I-MIBG; Diagnostic Test: Blood samples
Sponsor: Herlev Hospital
Recruiting - Conditions: Spinal Cord Injuries; Traumatic Brain Injury; Spina Bifida; Cerebral Palsy; Stroke; Parkinson Disease; Multiple Sclerosis
Intervention: Other: Movement-2-Music (M2M)
Sponsors: University of Alabama at Birmingham; Lakeshore Foundation; Young Men's Christian Association (YMCA)
Not yet recruiting - Conditions: Movement Disorders; Essential Tremor; Holmes Tremor; Parkinson's Disease; Wilson's Disease; Huntington's Disease; Dystonia; Tardive Dyskinesia; Orofacial Dyskinesias
Intervention: Device: Transcranial ExAblate System
Sponsor: InSightec
Recruiting - Conditions: Patients With Synucleinopathies; Neurogenic Orthostatic Hypotension; Pure Autonomic Failure; REM Sleep Behavior Disorder; Parkinson Disease; Dementia With Lewy Bodies; Multiple System Atrophy; Shy-Drager Disease
Intervention:
Sponsor: New York University School of Medicine
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Vascular Dementia; Lewy Body Disease; Lewy Body Dementia With Behavioral Disturbance (Disorder); Dementia, Mixed; Parkinson-Dementia Syndrome; Chronic Traumatic Encephalopathy; Huntington's Dementia; Wernicke Korsakoff Syndrome; Traumatic Brain Injury; Dementia, Multi-Infarct; Autism; Autism Spectrum Disorder; Autistic Behavior; Autistic Disorder, Current or Active State; Cadasil
Interventions: Procedure: Intravenous Bone Marrow Stem Cell (BMSC) Fraction; Procedure: Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction; Procedure: Near Infrared Light
Sponsor: MD Stem Cells
Recruiting - Conditions: Neurologic Disorders; Nervous System Diseases; Neurodegenerative Diseases; Neurological Disorders; Stroke; Traumatic Brain Injury; Cadasil; Chronic Traumatic Encephalopathy; Cerebral Infarction; Cerebral Ischemia; Cerebral Stroke; Cerebral Hemorrhage; Parkinson; Multi-System Degeneration; MSA - Multiple System Atrophy; Progressive Supranuclear Palsy; ALS; Amyotrophic Lateral Sclerosis; Neuropathy; Diabetic Neuropathies
Interventions: Procedure: Intravenous BMSC; Procedure: Intranasal BMSC
Sponsors: MD Stem Cells; The Healing Institute
Recruiting - Conditions: Dementia; Parkinson; Altered Behavior in Alzheimer Disease; Demyelinating Autoimmune Diseases, CNS; Demyelinating Sensorimotor Neuropathy; Corticobasal Degeneration
Interventions: Procedure: Microcannula Harvest Adipose; Device: Centricyte 1000; Procedure: Sterile Normal Saline Infusion
Sponsors: Regeneris Medical; Global Alliance for Regenerative Medicine; Robert W. Alexander, MD, FICS; Regeneris Medical Inc
Not yet recruiting - Conditions: Autistic Disorders Spectrum; Adhd; Asperger Syndrome; Alzheimer Disease; Parkinson; Tremor Essential; Dementia, Alzheimer Type; Lewy Body Dementia With Behavioral Disturbance (Disorder); Dementia With Lewy Bodies; Dementia Frontal
Intervention:
Sponsor: Rutgers University
Recruiting - Condition: Symptomatic Neurogenic Orthostatic Hypotension
Interventions: Drug: TD-9855; Drug: Placebo
Sponsor: Theravance Biopharma
Not yet recruiting - Condition: Symptomatic Neurogenic Orthostatic Hypotension
Interventions: Drug: TD-9855; Drug: Placebo
Sponsor: Theravance Biopharma
Recruiting - Condition: Nervous System Disease
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Healthy; Neurodegenerative Disease
Intervention:
Sponsor: University of California, San Francisco
Recruiting - Condition: All Diagnosed Health Conditions
Intervention:
Sponsor: Sanguine Biosciences
Recruiting - Condition: Neurologic Disorders
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Dementia-related Psychosis
Interventions: Drug: Placebo; Drug: Pimavanserin 34 mg; Drug: Pimavanserin 20 mg
Sponsor: ACADIA Pharmaceuticals Inc.
Recruiting
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