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- Condition: Parkinson
Interventions: Other: Surface EMG, MRI and PET Scan; Other: Surface EMG
Sponsors: Spaulding Rehabilitation Hospital; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Condition: Parkinson Disease
Interventions: Device: Active tPCS; Device: Sham tPCS; Drug: Levodopa tablet
Sponsor: Western University, Canada
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: Boston Scientific Vercise PC IPG with directional DBS lead
Sponsors: University of Alabama at Birmingham; National Institutes of Health (NIH); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Interventions: Drug: P2B001; Drug: Rasagiline; Drug: Pramipexole; Drug: Pramipexole ER
Sponsor: Pharma Two B Ltd.
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Computer task assessing cognition; Behavioral: Impulsive-Compulsive Disorders in Parkinson's Disease; Behavioral: Montreal Cognitive Assessment
Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson's Disease
Interventions: Dietary Supplement: Niacin; Dietary Supplement: Niacinamide; Other: Placebo
Sponsor: VA Office of Research and Development
Not yet recruiting - Condition: Parkinson's Disease
Intervention:
Sponsors: Columbia University; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Condition: Parkinson Disease
Intervention: Device: Medtronic DBS Therapy for Parkinson's disease
Sponsor: MedtronicNeuro
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Nicotine Nasal Spray 10 MG/ML (0.5 MG/SPRAY)
Sponsors: El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez; Howard University
Not yet recruiting - Condition: Parkinson's Disease
Intervention: Device: Bioinduction "Picostim" Deep Brain Stimulation system
Sponsors: North Bristol NHS Trust; Bioinduction
Not yet recruiting - Condition: Parkinson Disease
Interventions: Other: Training with Neurofeedback; Other: The other Training with Neurofeedback
Sponsors: Osaka University; Japan Agency for Medical Research and Development
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Nabilone 0.25 mg
Sponsor: Medical University Innsbruck
Recruiting - Condition: Parkinson Disease
Intervention: Diagnostic Test: Clinical evaluation of vision and eye tests
Sponsor: Neuromed IRCCS
Recruiting - Condition: Parkinson Disease
Interventions: Drug: DNL151 low dose; Drug: DNL151 high dose; Drug: Placebo
Sponsor: Denali Therapeutics Inc.
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Nabilone 0.25 mg; Drug: Placebo
Sponsor: Medical University Innsbruck
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: Rush University Medical Center; California Institute of Technology; Purdue University
Recruiting - Condition: Parkinson's Disease
Intervention: Diagnostic Test: genetic diagnosis
Sponsor: Zhujiang Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Drug: DNL201 low dose; Drug: DNL201 high dose; Drug: Placebo
Sponsor: Denali Therapeutics Inc.
Recruiting - Condition: Parkinson's Disease and Parkinsonism
Intervention: Device: Lab Assay for seven genetic variants for Parkinson's Disease
Sponsors: University of Rochester; University of Rochester - CHeT/CTCC; Fulgent Laboratories; Indiana University; University of Florida
Recruiting - Condition: Parkinson Disease
Intervention: Other: Taïso
Sponsor: University Hospital, Angers
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: photobiomodulation; Device: placebo photobiomodulation
Sponsor: University of Nove de Julho
Not yet recruiting - Condition: Parkinson's Disease
Interventions: Drug: Apomorphine; Other: Best Medical Treatment
Sponsor: Rennes University Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Other: Donor FMT; Other: Autologous FMT
Sponsors: University Ghent; University Hospital, Ghent; the Flanders Institute for Biotechnology; Research Foundation Flanders; Parkinson's disease patient organizations: Vlaamse Parkinson Liga, Parkili
Recruiting - Condition: Parkinson's Disease
Intervention: Behavioral: Simon Task with high-density EEG recording
Sponsors: Rennes University Hospital; Université de Rennes, Laboratoire du Traitement du Signal et de l'Image (LTSI); Institut des Neurosciences Cliniques de Rennes (INCR); Association des Parkinsoniens d'Ille-et-Vilaine (APIV)
Recruiting - Condition: Parkinson Disease
Interventions: Drug: OXB-102; Other: Imitation Surgical Procedure (ISP)
Sponsors: Axovant Sciences Ltd.; Oxford BioMedica
Recruiting - Condition: Parkinson Disease
Interventions: Dietary Supplement: Nicotinamide Riboside; Drug: Placebo
Sponsor: Haukeland University Hospital
Not yet recruiting - Condition: Parkinson Disease
Intervention: Diagnostic Test: observational study
Sponsor: Istanbul Medeniyet University
Recruiting - Condition: Parkinson Disease
Intervention: Device: Wearable real-time feedback device
Sponsors: Arizona State University; St. Joseph's Hospital and Medical Center, Phoenix
Not yet recruiting - Condition: Parkinson Disease
Intervention: Biological: Injection of Umbilical cord derived MSCs
Sponsor: University of Jordan
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Deferiprone; Drug: Placebo
Sponsors: University Hospital, Lille; European Commission; ApoPharma
Recruiting - Condition: Parkinson's Disease
Interventions: Behavioral: Aerobic walking; Behavioral: Usual care with PD specific health education
Sponsors: VA Office of Research and Development; University of Iowa
Recruiting - Condition: Parkinson's Disease
Intervention: Device: Light Therapy Device
Sponsor: Massachusetts General Hospital
Recruiting - Condition: Parkinson's Disease
Interventions: Behavioral: High Intensity Aerobic program; Other: Conventional Physical Therapy; Behavioral: Medium Intensity Aerobic program
Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: Exablate Subthalamotomy; Device: Sham Exablate Subthalamotomy
Sponsor: InSightec
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Intensive running; Behavioral: Physiotherapy
Sponsors: Chinese University of Hong Kong; The Hong Kong Polytechnic University; Prince of Wales Hospital, Shatin, Hong Kong
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Liraglutide; Drug: Placebo
Sponsors: Cedars-Sinai Medical Center; The Cure Parkinson's Trust; Novo Nordisk A/S
Recruiting - Condition: Parkinson's Disease Dementia
Interventions: Drug: Ceftriaxone; Other: Placebo
Sponsor: BrainX Corporation
Recruiting - Condition: Parkinson Disease
Interventions: Drug: N-Acetylcysteine; Procedure: Lumbar Puncture; Radiation: Fluoroscopy
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Interventions: Other: Game based treadmill Platform; Other: Control Group
Sponsor: University of Manitoba
Not yet recruiting - Condition: Parkinson Disease
Intervention: Behavioral: Physical Therapy
Sponsors: Washington University School of Medicine; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: University of Washington
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Terazosin 5 MG; Drug: Placebo oral capsule
Sponsors: Jordan Schultz; University of Iowa
Not yet recruiting - Condition: Parkinson Disease
Interventions: Other: mHealth delivered exercise program; Other: Exercise only
Sponsors: Boston University Charles River Campus; Washington University School of Medicine
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: [year1] dual-task training with task priority strategy; Behavioral: [year2-3] dual-task training with internal and external focus
Sponsor: National Taiwan University Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: aerobic exercise; Behavioral: rest; Behavioral: motor learning
Sponsors: University of Erlangen-Nürnberg; German Foundation for Neurology; Department of Molecular Neurology, Faculty of Medicine, University Erlangen-Nürnberg; Klinik für Neurologie, Krankenhaus Rummelsberg
Recruiting - Condition: Parkinson Disease
Interventions: Device: RMBand lower dose; Device: RMBand higher dose
Sponsor: Virginia Commonwealth University
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: SQJZ herbal mixtures; Drug: Placebo
Sponsor: Dongzhimen Hospital, Beijing
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Rivastigmine transdermal patch
Sponsors: University of Maryland, College Park; National Institute on Aging (NIA)
Recruiting - Condition: Parkinson Disease
Intervention: Radiation: MRI if indicated
Sponsor: Alaa E Ahmed
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: Training with HWA device; Other: Usual Care
Sponsors: Ohio State University; Michael J. Fox Foundation for Parkinson's Research; Honda Research and Development Americas, Inc
Recruiting - Condition: Parkinson Disease
Interventions: Diagnostic Test: LBT-3627; Diagnostic Test: Immunological profiling
Sponsors: Longevity Biotech; Michael J. Fox Foundation for Parkinson's Research; Corporal Michael J. Crescenz VA Medical Center - Philadelphia
Recruiting - Condition: Parkinson Disease
Intervention: Device: Werable sensors
Sponsors: Fondazione Don Carlo Gnocchi Onlus; Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Catholic University of the Sacred Heart
Not yet recruiting - Condition: Parkinson's Disease
Interventions: Drug: Continuous intrajejunal infusion of levodopa-carbidopa; Device: deep brain stimulation
Sponsors: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); ZonMw: The Netherlands Organisation for Health Research and Development
Recruiting - Condition: Parkinson Disease
Interventions: Device: Active Comparator: Active tDCS and Active TUS; Device: Sham Comparator: Sham TDCS and Sham TUS; Other: Physical Therapy
Sponsors: Spaulding Rehabilitation Hospital; Highland Instruments, Inc.
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: Dental Mouthpiece
Sponsor: Washington University School of Medicine
Recruiting - Condition: Parkinson Disease
Intervention: Device: Spinal cord stimulation
Sponsor: Western University, Canada
Recruiting - Condition: Parkinson Disease
Interventions: Biological: VY-AADC02; Other: Placebo
Sponsors: Neurocrine Biosciences; Voyager Therapeutics
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Ganoderma; Drug: Placebos
Sponsor: Xuanwu Hospital, Beijing
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Cannabidiol; Other: Placebo
Sponsors: University of Colorado, Denver; Colorado Department of Public Health and Environment
Recruiting - Condition: Parkinson Disease
Intervention: Other: Usual care
Sponsors: Oxford Brookes University; European Parkinson’s Therapy Centre
Recruiting - Condition: Parkinsons
Intervention: Radiation: PiB and VAT
Sponsors: Washington University School of Medicine; National Institutes of Health (NIH); National Institute of Neurological Disorders and Stroke (NINDS); National Institute on Aging (NIA)
Recruiting - Condition: Parkinson Disease
Intervention: Device: Alternating DBS
Sponsors: University of Oxford; University College, London
Recruiting - Condition: Parkinson Disease
Interventions: Other: Neurologic Music Therapy; Other: Occupational Therapy; Other: Music Supported Therapy
Sponsors: University of Colorado, Denver; National Center for Complementary and Integrative Health (NCCIH)
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: National Parkinson Foundation
Recruiting - Condition: Parkinson's Disease
Intervention: Drug: Gold Nanocrystals
Sponsors: Clene Nanomedicine; University of Texas Southwestern Medical Center
Recruiting - Condition: Parkinson Disease
Intervention: Procedure: Response Inhibition and Deep Brain Stimulation in Parkinson's disease
Sponsor: University of Alabama at Birmingham
Not yet recruiting - Condition: Parkinson Disease
Interventions: Other: chest PNF; Other: Conventional
Sponsor: Subhasish Chatterjee
Recruiting - Condition: Parkinson's Disease
Interventions: Device: TENS; Device: Control
Sponsor: University Hospital, Toulouse
Recruiting - Condition: Parkinson Disease
Interventions: Procedure: Static, dynamic and functional balance exercises; Procedure: Static, dynamic and functional balance exercises with dual task
Sponsor: Istanbul University-Cerrahpasa
Not yet recruiting - Condition: Parkinson Disease
Intervention: Other: High-Intensity Aerobic Exercise
Sponsors: The Cleveland Clinic; National Institutes of Health (NIH)
Not yet recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Intelligent cueing; Behavioral: Feedback about the number of steps
Sponsors: Tel-Aviv Sourasky Medical Center; KU Leuven; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Condition: Parkinson Disease
Intervention: Device: Electrophysiological recording and measurement devices
Sponsors: Prof. Dr. Volker Arnd Coenen; University of Freiburg
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Brisk walking and balance training; Behavioral: Upper limb exercise
Sponsor: The Hong Kong Polytechnic University
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Placebo oral capsule; Drug: PXT002331 - dose 1; Drug: PXT002331 - dose 2
Sponsor: Prexton Therapeutics
Recruiting - Condition: Parkinson Disease
Intervention: Drug: DPA-714-PET/MRI
Sponsor: University of Alabama at Birmingham
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: Handwriting Practice
Sponsors: Oxford Brookes University; European Parkinson’s Therapy Centre
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: MultiContext for PD Strategy Training; Behavioral: Standard of Care
Sponsors: Washington University School of Medicine; National Institute on Aging (NIA)
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: KDT-3594; Drug: Pramipexole
Sponsor: Kissei Pharmaceutical Co., Ltd.
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Qigong exercise; Behavioral: Mild body exercise
Sponsor: University of Kansas Medical Center
Recruiting - Condition: Parkinson Disease
Intervention: Device: PDVibe2
Sponsors: Virginia Commonwealth University; Michael J. Fox Foundation for Parkinson's Research
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Donepezil; Drug: Placebo
Sponsors: Oregon Health and Science University; Medical Research Foundation, Oregon
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Ropinirole oral product; Drug: Ropinirole Implant
Sponsor: Titan Pharmaceuticals
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: University Hospital, Lille
Recruiting - Condition: Parkinson's Disease
Intervention: Other: Nocturnal symptoms
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Recruiting - Condition: Parkinson Disease
Intervention: Device: Transcranial Direct Current Stimulation
Sponsor: Federal University of Paraíba
Recruiting - Condition: Parkinson Disease
Intervention: Procedure: fecal microbial transplantation
Sponsor: Soroka University Medical Center
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Ioflupane I 123
Sponsor: Julie Gurwell
Recruiting - Condition: Parkinson Disease
Intervention: Other: Mediterranean Diet
Sponsor: University of Florida
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Rifaximin; Other: Placebo
Sponsors: University of California, San Francisco; Nova Southeastern University; Gateway Institute for Brain Research
Recruiting - Conditions: Parkinson Disease; Parkinson
Intervention: Device: Medtronic RC+S DBS system
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: Body Sensor Network
Sponsors: RWTH Aachen University; Medical Information Technology (MedIT), RWTH Aachen University
Not yet recruiting - Condition: Parkinson Disease
Interventions: Other: Clinical Pilates; Other: Classic Physiotherapy
Sponsor: European University of Lefke
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: transcranial magnetic stimulation
Sponsor: University Hospital, Grenoble
Not yet recruiting - Condition: Parkinson Disease
Interventions: Behavioral: non-random whole body vibration; Behavioral: occupational therapy
Sponsor: Chang Gung University
Recruiting - Condition: Parkinson's Disease
Interventions: Dietary Supplement: niacin; Other: placebo
Sponsor: VA Office of Research and Development
Recruiting - Condition: Parkinson Disease
Interventions: Device: Jintronix; Other: Booklet
Sponsors: Université du Québec a Montréal; Weston Brain Institute
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: Assistive Technology Clinic, Canada; University of Cincinnati; The Cleveland Clinic; University Health Network, Toronto; University of Michigan; Rush University; The Parkinson Study Group
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - Condition: Parkinson Disease
Intervention: Device: Spinal Cord Stimulator (SCS)
Sponsor: Nora Vanegas-Arroyave
Not yet recruiting - Condition: Parkinson Disease
Intervention: Drug: Ips-nsc cells
Sponsors: Allife Medical Science and Technology Co., Ltd.; The First People's Hospital of Yunnan Province/First People's Hospital of Yunan Provinve New Kunhua Hospital; Henan Provincial Hospital; Beijing Hospital
Not yet recruiting - Condition: Parkinson Disease
Interventions: Other: Virtual reality intervention; Other: Dual task intervention; Other: Conventional physiotherapy
Sponsor: Asir John Samuel
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Bumetanide white, oblong, scored tablet; Drug: Placebo white, oblong, scored tablet
Sponsor: B&A Therapeutics
Recruiting - Condition: Parkinson Disease
Interventions: Other: cognitive examination; Other: viewing of video; Other: Iowa Gambling Task
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: BrainEver
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Clarithromycin; Drug: Placebo
Sponsors: Nicolaas Bohnen, MD, PhD; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Zolpidem; Other: Placebo
Sponsors: Aston University; University Hospital Birmingham NHS Foundation Trust
Recruiting - Condition: Parkinson's Disease
Intervention: Other: Gait training
Sponsors: VA Office of Research and Development; University of Washington
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: Danish Research Centre for Magnetic Resonance; Bispebjerg Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Other: Scalp Acupuncture; Other: Body Acupenture
Sponsor: Taipei Veterans General Hospital, Taiwan
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: Personal KinetiGraph® (PKG®) Watch; Device: Personal KinetiGraph® (PKG®) Report
Sponsor: Global Kinetics Corporation
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: AMPS Gondola; Device: Sham Gondola
Sponsor: IRCCS San Raffaele
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Flumazenil; Drug: Placebo
Sponsors: University of Michigan; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson Disease
Intervention: Dietary Supplement: Oral D-Mannitol of Placebo
Sponsor: Hadassah Medical Organization
Recruiting - Condition: Parkinson Disease
Intervention: Other: Multimodal overground locomotor training
Sponsor: George Mason University
Recruiting - Condition: Parkinson Disease
Intervention: Drug: HB-adMSC
Sponsor: Hope Biosciences
Available - Condition: Parkinson Disease
Interventions: Drug: Hydrogen; Drug: Placebo oral tablet
Sponsor: Stony Brook University
Recruiting - Condition: Parkinson Disease
Intervention: Device: Personal KinetiGraph™ (PKG™)
Sponsor: Global Kinetics Corporation
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Home Visit Program; Behavioral: Caregiver Mentorship Program
Sponsor: Rush University Medical Center
Recruiting - Condition: Parkinson's Disease
Interventions: Other: Active tDCS plus gait training; Other: Sham tDCS plus gait training
Sponsor: National Yang Ming University
Not yet recruiting - Condition: Parkinson Disease
Intervention: Behavioral: Speech-to-noise feedback
Sponsors: Lawson Health Research Institute; University of Western Ontario, Canada
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: Tactile Stimulation Glove; Device: Sham Stimulation Glove
Sponsor: Casey H. Halpern
Not yet recruiting - Condition: Parkinson Disease
Intervention: Other: cervical spinal stabilization exercise
Sponsors: Hacettepe University; BElibol; NKöse; GYÇakmaklı; SAksoy; RGöçmen
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Opicapone; Drug: Levodopa (L-DOPA) + Standard care
Sponsor: Bial - Portela C S.A.
Not yet recruiting - Condition: Parkinson's Disease
Intervention: Drug: Ursonorm
Sponsors: Sheffield Teaching Hospitals NHS Foundation Trust; JP Moulton Charitable Foundation; PRO.MED.CS Praha a.s.; Clinical Trials Research Unit, University of Sheffield
Recruiting - Condition: Parkinson Disease
Interventions: Drug: IPT803; Genetic: Optional pharmacogenetic assessment; Other: Questionnaires; Other: Optional Blood-Oxygen-level Dependent functionalMRI; Other: Motor Assessments before taking regular PD treatment; Other: Motor Assessments on regular PD treatment
Sponsor: Tools4Patient
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: KW-6356; Drug: Placebo
Sponsor: Kyowa Kirin Co., Ltd.
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: BIIB094; Drug: Placebo
Sponsors: Biogen; Ionis Pharmaceuticals, Inc.
Recruiting - Condition: Parkinson Disease
Intervention: Device: ExAblate Neuro Thalamotomy Treatment
Sponsor: InSightec
Recruiting - Condition: Idiopathic Parkinson Disease
Intervention: Drug: XADAGO (safinamide)
Sponsor: US WorldMeds LLC
Recruiting - Conditions: Parkinson Disease; PARK8
Intervention: Genetic: Blood Test
Sponsor: Centogene AG Rostock
Recruiting - Condition: Parkinson Disease
Interventions: Drug: PRIM-DJ2727; Drug: Placebo oral capsule
Sponsors: The University of Texas Health Science Center, Houston; Kelsey Research Foundation
Recruiting - Condition: Parkinson Disease
Intervention: Other: No Intervention - Observational Study
Sponsors: Oregon Health and Science University; Portland VA Medical Center; Oregon Clinical and Translational Research Institute
Recruiting - Condition: Parkinson's Disease
Intervention: Biological: Intracerebral microinjections
Sponsor: NeuroGeneration
Not yet recruiting - Condition: Parkinson Disease
Intervention: Drug: DaTscan
Sponsors: Ken Marek, MD; Institute for Neurodegenerative Disorders
Recruiting - Condition: Parkinson Disease
Intervention: Device: Stimulation
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: PAT sessions
Sponsor: NYU Langone Health
Recruiting - Condition: Parkinson Disease
Interventions: Device: adaptive Deep Brain Stimulation; Device: conventional Deep Brain Stimulation
Sponsor: Newronika
Recruiting - Condition: Parkinson Disease
Intervention: Drug: ursodeoxycholic acid
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - Condition: Idiopathic Parkinson Disease
Interventions: Behavioral: Lee Silverman Voice Treatment; Device: SpeechVive; Behavioral: Control
Sponsors: University of Massachusetts, Amherst; National Institute on Deafness and Other Communication Disorders (NIDCD); Purdue University
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Safinamide; Other: Placebo
Sponsor: Zambon SpA
Recruiting - Condition: Parkinson Disease Psychosis
Interventions: Drug: SEP-363856; Drug: Placebo capsule
Sponsor: Sunovion
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: BIIB054; Drug: Placebo
Sponsor: Biogen
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Rhythmic Auditory Stimulation; Behavioral: Kinesiology
Sponsors: Pontifical Catholic University of Argentina; National Council of Scientific and Technical Research, Argentina; Hospital Nacional Profesor Alejandro Posadas; University of Buenos Aires
Not yet recruiting - Condition: Parkinson's Disease
Interventions: Device: active light therapy : Light therapy: DayVia lamp 10000 lux; Device: Placebo light therapy
Sponsor: University Hospital, Strasbourg, France
Recruiting - Conditions: Parkinson Disease; Parkinson Disease 10
Interventions: Other: Nordic Walking; Other: Jogging; Other: Dance; Other: Pilates Training
Sponsors: Federal University of Rio Grande do Sul; Aline Nogueira Haas; Flávia Gomes Martinez
Recruiting - Condition: Motor OFF Episodes Associated With Parkinson's Disease
Interventions: Drug: APL-130277; Drug: subcutaneous apomorphine
Sponsor: Sunovion
Recruiting - Condition: Parkinson's Disease
Intervention: Procedure: Bilateral subthalamic stimulation
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - Condition: Parkinson's Disease
Interventions: Combination Product: ND0612 Solution for SC infusion; Combination Product: Placebo for SC infusion; Drug: Carbidopa and Levodopa 25mg/100mg; Drug: Placebo for Carbidopa and Levodopa 25mg/100mg
Sponsor: NeuroDerm Ltd.
Not yet recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Pramipexole SR; Drug: Pramipexole IR
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: University of Michigan
Recruiting - Condition: Parkinson Disease
Interventions: Other: Transcranial Magnetic Stimulation; Behavioral: Lee Silverman Voice Treatment
Sponsors: Le Bonheur Children's Hospital; Michael J. Fox Foundation for Parkinson's Research; University of Tennessee Health Science Center; University of Memphis
Recruiting - Condition: Parkinson's Disease (Disorder)
Interventions: Drug: IR CD-LD; Drug: IPX203 ER CD-LD; Other: IPX203 placebo; Other: IR CD-LD placebo
Sponsor: Impax Laboratories, LLC
Recruiting - Conditions: Parkinson Disease, PARK8; Parkinson Disease; Idiopathic Parkinson Disease
Intervention:
Sponsors: King's College London; GlaxoSmithKline
Recruiting - Condition: Parkinson's Disease
Intervention: Other: patients with Parkinson's disease
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: Rasagiline; Other: Placebo; Device: Magnetic Resonance Imaging; Device: functional Magnetic Resonance Imaging; Other: Physical Function Performance Test
Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: GZ/SAR402671; Drug: Placebo
Sponsor: Genzyme, a Sanofi Company
Recruiting - Condition: Parkinson Disease
Interventions: Drug: GRF6021; Other: Placebo
Sponsors: Alkahest, Inc.; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Condition: Advanced Parkinson's Disease
Intervention:
Sponsor: AbbVie
Recruiting - Condition: Parkinson Disease
Intervention: Other: Rhythmic Auditory Stimulation
Sponsor: University of North Carolina, Chapel Hill
Recruiting - Condition: Parkinson's Disease
Intervention: Procedure: Magnetic Resonance Imaging (MRI)
Sponsors: University Hospital, Clermont-Ferrand; France Parkinson Association; Federation for Brain Research; NS-PARK Network
Recruiting - Condition: Parkinson Disease
Intervention: Drug: APL-130277
Sponsor: Sunovion
Recruiting - Condition: Parkinson's Disease
Intervention: Device: Transcranial ExAblate
Sponsor: InSightec
Recruiting - Condition: Advanced Parkinson's Disease
Intervention: Drug: ABT-SLV187
Sponsor: AbbVie
Recruiting - Condition: Parkinson's Disease (PD)
Intervention: Drug: ABBV-951
Sponsor: AbbVie
Recruiting - Condition: Interest of Hydrophysiotherapy Care in Parkinson Disease's Non-motor Symptoms
Interventions: Other: Aquatic rehabilitation; Other: Land based physical activities; Other: Conventional rehabilitation
Sponsors: Central Hospital, Nancy, France; Institut Régional de Médecine Physique et de Réadaptation
Not yet recruiting - Condition: Early Parkinson Disease
Interventions: Drug: K0706; Other: placebo
Sponsor: Sun Pharma Advanced Research Company Limited
Recruiting - Conditions: Parkinson's Disease; Parkinsonism
Intervention:
Sponsors: University College, London; Parkinson's UK; Royal Free Hospital NHS Foundation Trust
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Probiotic Agent; Drug: Placebo oral capsule
Sponsor: University of Malaya
Recruiting - Condition: Parkinson's Disease Dementia
Interventions: Drug: Ambroxol; Other: Placebo
Sponsors: Lawson Health Research Institute; Weston Brain Institute; University of Western Ontario, Canada; London Health Sciences Centre
Recruiting - Condition: Parkinson Disease
Interventions: Drug: THN102 Dosage A; Drug: THN102 Dosage B; Drug: THN102 Dosage C
Sponsor: Theranexus
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: University Hospital, Lille; France Parkinson Association
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Active drug: pimavanserin 17mg (2 strength tablets); Drug: Placebo: 2 tablets containing same excipients except active compound; Behavioral: Assessment of severity of ICD (impulse control disorders); Behavioral: Assessment of motor and non-motors symptoms of PD Evaluation of hyper- and hypodopaminergic behaviors; Behavioral: Assessment of quality of life; Behavioral: Assessment of depression; Behavioral: Assessment of cognition; Behavioral: Assessment of severity of Parkinson Disease; Procedure: Blood analysis; Procedure: Cardiac monitoring
Sponsors: University Hospital, Strasbourg, France; NS-PARK; EUCLID; F-CRIN
Not yet recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Spinning Class; Behavioral: Yoga Class; Behavioral: Dance Class
Sponsors: Premier Health; Parkinson's Disease Foundation; Dartmouth-Hitchcock Medical Center
Recruiting - Condition: Parkinson's Disease (PD)
Intervention:
Sponsor: AbbVie
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Pridopidine; Drug: Placebo
Sponsor: Prilenia
Recruiting - Condition: Parkinson's Disease (PD)
Intervention: Drug: ABBV-951
Sponsor: AbbVie
Recruiting - Condition: Parkinson's Disease
Intervention: Other: magnetic resonance imaging
Sponsor: Poitiers University Hospital
Recruiting - Conditions: Parkinson Disease; Driving Impaired
Interventions: Device: Lane change assistance system; Behavioral: Active Control
Sponsor: Western University, Canada
Recruiting - Condition: Parkinson Disease
Interventions: Device: Active tDCS; Device: Sham tDCS
Sponsor: NYU Langone Health
Recruiting - Condition: Parkinson Disease
Interventions: Device: ExAblate Pallidotomy; Device: Sham ExAblate Pallidotomy
Sponsor: InSightec
Recruiting - Condition: Idiopathic Parkinson's Disease (at Later Stage)
Intervention: Drug: Safinamide
Sponsors: Alain Kaelin; Clinical Trial Unit Ente Ospedaliero Cantonale
Recruiting - Conditions: Parkinson Disease; Neurodegenerative Diseases
Interventions: Dietary Supplement: Nicotinamide Riboside; Other: Placebo
Sponsor: Haukeland University Hospital
Recruiting - Condition: Parkinson Disease
Interventions: Drug: PR Oxycodone; Drug: Levodopa; Drug: Oxycodone Placebo; Drug: Levodopa placebo
Sponsor: University Hospital, Toulouse
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsor: National Institute of Mental Health (NIMH)
Recruiting - Condition: Idiopathic Parkinson Disease
Interventions: Drug: Safinamide Methanesulfonate; Drug: Safinamide methanesulfonate matching placebo
Sponsor: Zambon SpA
Recruiting - Conditions: Parkinson Disease; Executive Dysfunction
Intervention: Device: Computer-based cognitive training
Sponsor: Bispebjerg Hospital
Recruiting - Condition: Parkinsons Disease With Dementia
Interventions: Drug: High dose ANAVEX2-73; Drug: Mid dose ANAVEX2-73; Drug: Placebo oral capsule
Sponsors: Anavex Life Sciences Corp.; Anavex Germany GmbH
Recruiting - Conditions: Parkinson Disease; Rehabilitation
Interventions: Procedure: Stand-Up Paddle Rehabilitation; Procedure: Physiotherapy Rehabilitation
Sponsor: FLABEAU Olivier
Recruiting - Condition: Oxidative Stress is an Important Cause of Parkinson's Disease
Intervention: Drug: Idebenone/placebo
Sponsors: Second Affiliated Hospital of Soochow University; Qilu Pharmaceutical Co., Ltd.
Not yet recruiting - Conditions: Oral Health; Parkinson Disease
Intervention: Behavioral: Delivery of oral hygiene advices
Sponsors: University Hospital, Bordeaux; Capionis; France Parkinson Association
Recruiting - Conditions: Parkinson Disease; Bone Loss
Intervention:
Sponsor: T.C. ORDU ÜNİVERSİTESİ
Not yet recruiting - Condition: Virtual Reality; Rehabilitation; Parkinson's Disease
Interventions: Device: Virtual reality-based interactive treadmill training; Device: Treadmill training without VR-based interaction
Sponsors: Seoul National University Hospital; Ministry of Trade, Industry & Energy(MOTIE, Korea)
Recruiting - Condition: Parkinsons Disease With Dementia
Intervention: Device: MR Guided Focused Ultrasound
Sponsor: InSightec
Recruiting - Conditions: Parkinson's Disease; Mild Cognitive Impairment
Interventions: Behavioral: cognitive training; Behavioral: active control cognitive training; Behavioral: memory strategy training
Sponsor: VA Office of Research and Development
Not yet recruiting - Conditions: Parkinson Disease; Gaucher Disease
Intervention:
Sponsor: Lysosomal and Rare Disorders Research and Treatment Center, Inc.
Recruiting - Conditions: Aging Disorder; Parkinson Disease
Intervention: Other: Metrology of motor behavior
Sponsors: Central Hospital, Nancy, France; OHS - Office d'Hygiène Sociale; ONPA - Office Nancéien des Personnes Agées; University of Lorraine
Not yet recruiting - Conditions: Parkinson's Disease; Healthy Controls Group - Age and Sex-matched
Interventions: Procedure: Brain MRI; Procedure: TMS-EEG; Behavioral: Behavioral and cognitive battery; Other: Clinical evaluation and clinical scales
Sponsors: University Hospital, Grenoble; University Hospital, Clermont-Ferrand; Grenoble Institut des Neurosciences
Recruiting - Conditions: Parkinson Disease; Anxiety
Intervention: Behavioral: Interpretation bias training
Sponsor: King's College London
Recruiting - Conditions: Parkinson Disease; Apathy
Intervention: Behavioral: Gameficiation
Sponsor: University of Pennsylvania
Recruiting - Conditions: Anxiety Disorders; Parkinson Disease
Interventions: Drug: rotigotine transdermal patch; Drug: placebo
Sponsors: Johns Hopkins University; National Institute on Aging (NIA)
Recruiting - Condition: Parkinson Disease Psychosis
Intervention: Other: Real-world, non-interventional
Sponsor: ACADIA Pharmaceuticals Inc.
Recruiting - Conditions: Parkinson Disease; Healthy Volunteer
Intervention: Drug: [18F]NOS
Sponsor: University of Pennsylvania
Recruiting - Condition: Parkinson Disease Psychosis
Interventions: Drug: Saracatinib; Drug: Placebo Oral Tablet
Sponsors: King's College London; AstraZeneca; King's College Hospital NHS Trust
Recruiting - Conditions: Parkinson Disease; Urinary Disease Other
Interventions: Behavioral: cognitive training; Behavioral: pelvic floor training
Sponsors: University of Schleswig-Holstein; University of Kiel
Recruiting - Conditions: Parkinson Disease; Exercise Training
Interventions: Other: High Intensity Interval Training; Other: Continuous Moderate Intensity Training
Sponsors: University of Guelph; Parkinson Society Canada; YMCA
Recruiting - Conditions: Parkinson's; Anosognosia
Intervention: Behavioral: Questionnaires
Sponsor: University of Birmingham
Recruiting - Conditions: Overactive Bladder; Parkinson Disease
Interventions: Drug: solifenacin; Behavioral: Pelvic floor muscle exercise-based behavioral therapy
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Parkinson Disease; Mild Cognitive Impairment
Interventions: Device: transcranial direct current stimulation; Device: Sham (for transcranial direct current stimulation)
Sponsor: Sanford Health
Recruiting - Conditions: Parkinson Disease; Movement Disorders
Intervention:
Sponsors: Oregon Health and Science University; Portland VA Medical Center
Recruiting - Condition: Parkinson Disease
Intervention: Other: Rehabilitation intervention
Sponsor: Université de Sherbrooke
Not yet recruiting - Conditions: Parkinson Disease; Osteoporosis
Interventions: Drug: Zoledronic Acid 5Mg/Bag 100Ml Inj; Other: Placebo
Sponsors: California Pacific Medical Center Research Institute; National Institute on Aging (NIA); University of California, San Francisco; Duke University; University of Pittsburgh; Parkinson's Foundation
Not yet recruiting - Conditions: Parkinson Disease; Exercise Training; Cognitive Change
Interventions: Behavioral: SMARTfit training; Behavioral: Conventional physical training
Sponsors: University of Southern California; University of California, Irvine
Recruiting - Conditions: Parkinson Disease; Gait Disorders, Neurologic
Interventions: Other: Treadmill + VR; Other: Treadmill
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Recruiting - Conditions: Healthy; Parkinson Disease
Interventions: Drug: Lu AF82422; Drug: Placebo
Sponsor: H. Lundbeck A/S
Recruiting - Conditions: Depression; Parkinson's Disease
Interventions: Behavioral: Interpersonal Psychotherapy; Behavioral: Supportive Psychotherapy
Sponsors: Hopital Montfort; The Ottawa Hospital
Recruiting - Conditions: Exercise; Parkinson Disease
Intervention: Other: Exercise
Sponsor: Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Recruiting - Conditions: Transcranial Magnetic Stimulation; Parkinson Disease; Pain
Intervention: Device: Repetitive Transcranial Magnetic Stimulation
Sponsor: Xuanwu Hospital, Beijing
Recruiting - Condition: Parkinson Disease
Intervention: Diagnostic Test: Functional Activities Questionnaire
Sponsors: University Hospital Tuebingen; Sub-Investigator, Dr. Kathrin Brockmann, University Hospital of Tuebingen, Tuebingen, Germany; Advisory board, Prof. Dr. Thomas Gasser, University Hospital of Tuebingen, Tuebingen, Germany; Advisory board, Prof. Dr. Berg, Christian-Albrechts-University, Kiel, Germany
Recruiting - Conditions: Parkinson Disease; Anxiety; Depression
Intervention: Behavioral: Mindfulness-based cognitive therapy (MBCT)
Sponsors: University of California, San Francisco; National Parkinson Foundation
Recruiting - Conditions: Parkinson's Disease; Mindfulness Based Stress Reduction; Quality of Life
Interventions: Behavioral: Mindfulness Based Stress Reduction; Radiation: Psychoeducational/supportive care
Sponsor: VA Office of Research and Development
Not yet recruiting - Condition: Parkinson's Disease
Intervention: Drug: Levodopa
Sponsors: Kevin J. Black, MD; The Michael J. Fox Foundation for Parkinson's Research
Recruiting - Conditions: Parkinson Disease; Impulse Control Disorders
Interventions: Drug: Positron Emission Tomography using [11 Carbon]-3-amino-4-(2-dimethylaminomethylphenylsulfanyl)-benzonitrile ([11C]-DASB) and [18 Fluorine]-altanserin ([18F]-altanserin); Drug: Positron Emission Tomography using [18 Fluorine]-altanserin ([18F]-altanserin)
Sponsor: Hospices Civils de Lyon
Recruiting - Condition: Parkinson
Intervention: Device: Deep Brain Stimulation
Sponsor: Mustafa Kemal University
Recruiting - Condition: Parkinson's Disease
Interventions: Device: Deep brain stimulation; Device: Sham stimulation
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - Conditions: Parkinson Disease; Anxiety
Interventions: Dietary Supplement: Probiotic; Dietary Supplement: Placebo
Sponsors: University of British Columbia; The W. Garfield Weston Foundation
Not yet recruiting - Conditions: Parkinson Disease; Mild Cognitive Impairment
Intervention: Device: transcranial direct current stimulation
Sponsor: University of Manitoba
Recruiting - Conditions: Parkinson Disease; Anxiety
Intervention: Behavioral: Focused breathing
Sponsor: Virginia Commonwealth University
Recruiting - Conditions: Idiopathic Parkinson's Disease; Parkinson Disease; Depression
Intervention: Device: Transcranial Direct Current Stimulation
Sponsor: Johns Hopkins University
Recruiting - Condition: Parkinson Disease
Interventions: Device: Serious game; Device: Placebo serious game
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - Conditions: Parkinson Disease; Cognitive Impairment
Interventions: Behavioral: Working memory updating training; Behavioral: Placebo training
Sponsors: Umeå University; Karlstad University
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: treadmill training and overground gait training
Sponsor: National Taiwan University Hospital
Recruiting - Conditions: Parkinson's Disease; Mpulse Control Disorders
Interventions: Drug: placebo; Drug: Clonidine
Sponsor: Hospices Civils de Lyon
Recruiting - Conditions: Parkinson's Disease; Visual Hallucinations
Intervention: Diagnostic Test: Optical Coherence Tomography
Sponsors: University Hospital, Clermont-Ferrand; Fondation de France
Recruiting - Conditions: Parkinson Disease; Parkinsonism
Interventions: Biological: UB-312; Biological: Placebo
Sponsors: United Neuroscience Ltd.; Centre for Human Drug Research, Netherlands; Worldwide Clinical Trials
Recruiting - Condition: Parkinson Disease
Intervention: Other: Parkinson's disease nurse specialist care
Sponsors: Radboud University; ZonMw: The Netherlands Organisation for Health Research and Development; Zambon SpA
Recruiting - Condition: Parkinson Disease
Intervention: Device: DBS
Sponsors: University of Oxford; Oxford Brookes University
Not yet recruiting - Conditions: Parkinson Disease; Frail Elderly; Robotic Devices in Rehabilitation
Interventions: Other: control arm; Other: virtual reality games; Other: robotic treadmill
Sponsor: Istituto Nazionale di Ricovero e Cura per Anziani
Not yet recruiting - Conditions: Parkinson's Disease; Tremor
Interventions: Drug: CX-8998; Drug: Placebo
Sponsor: Jazz Pharmaceuticals
Not yet recruiting - Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) PatientsConditions: Alzheimer Disease; Parkinson Disease
Interventions: Drug: Metabolic Cofactor Supplementation; Drug: Sorbitol
Sponsors: Istanbul Medipol University Hospital; ScandiBio Therapeutics AB; Alanya Alaaddin Keykubat University; Sahlgrenska University Hospital, Sweden; KTH Royal Institute of Technology
Not yet recruiting - Conditions: Parkinson Disease; Cognitive Impairment
Intervention: Device: deep brain stimulation
Sponsor: University of California, Davis
Recruiting - Conditions: Parkinson Disease; Parkinsonian Disorders
Intervention: Diagnostic Test: Level of alpha-synuclein
Sponsor: Centre Hospitalier Universitaire de Nīmes
Recruiting - Conditions: Parkinson's Disease; Constipation
Intervention: Procedure: OMM treatment
Sponsor: New York Institute of Technology
Recruiting - Condition: Parkinson Disease
Intervention: Drug: [18F]P17-059
Sponsor: Five Eleven Pharma, Inc.
Not yet recruiting - Conditions: Parkinson's Disease; Mild Cognitive Impairment
Intervention:
Sponsors: University of Calgary; Canadian Institutes of Health Research (CIHR); Natural Sciences and Engineering Research Council, Canada; Montreal Neurological Institute and Hospital; McGill University
Recruiting - Conditions: Parkinson Disease; Orthostatic Hypotension
Intervention: Other: Abdominal Strengthening Exercise
Sponsor: Faizan Ahmed
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: Xiangya Hospital of Central South University
Recruiting - Condition: Parkinson's Disease
Intervention:
Sponsors: Zambon SpA; Iqvia Pty Ltd
Not yet recruiting - Condition: Parkinson Disease
Intervention: Other: Exercise
Sponsor: State University of New York - Upstate Medical University
Recruiting - Condition: Parkinson Disease
Intervention: Device: Dynamic Standing Table
Sponsor: University of Michigan
Recruiting - Condition: Parkinson Disease
Interventions: Behavioral: Adapted Tango Dancing; Behavioral: Behavioral Control (BC) Condition
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Parkinson's Disease; Multiple System Atrophy
Intervention: Device: Transcranial direct current stimulation
Sponsors: China Medical University Hospital; Ministry of Science and Technology, Taiwan
Recruiting - Condition: Parkinson Disease
Interventions: Device: AMADEO; Other: Training; Other: OT Training
Sponsor: IRCCS Centro Neurolesi "Bonino-Pulejo"
Not yet recruiting - Conditions: Parkinson Disease; Dyskinesia, Drug-Induced
Intervention: Drug: Intravenous Infusion
Sponsors: VA Office of Research and Development; Oregon Health and Science University
Recruiting - Conditions: Depression; Parkinson's Disease
Intervention: Behavioral: Cognitive-behavioral therapy (CBT)
Sponsor: Boston University Charles River Campus
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: Robotic Rehabilitation
Sponsor: IRCCS Centro Neurolesi "Bonino-Pulejo"
Recruiting - Condition: Parkinson Disease
Intervention: Behavioral: Protective Step Training
Sponsors: Arizona State University; University of Utah; Colorado State University
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsor: University Hospital, Montpellier
Recruiting - Conditions: Parkinson Disease; Dystonia
Interventions: Device: Summit RC+S; Diagnostic Test: 1-month pilot trial of Closed-loop vs. Open-loop Stimulation
Sponsor: University of California, San Francisco
Recruiting - Condition: Parkinson Disease
Intervention: Drug: Safinamide
Sponsor: IRCCS San Raffaele
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Capsaicin; Device: Resistive respiratory loads; Other: Event-related evoked potential using electroencephalography (EEG).; Procedure: Fluoroscopic swallow evaluation
Sponsors: University of Florida; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - Conditions: Parkinson Disease; Impaired Cognition; Alteration in Cognition
Interventions: Behavioral: Online cognitive training 1; Behavioral: Online cognitive training 2
Sponsors: VU University Medical Center; Dutch Parkinson Patient Association
Recruiting - Conditions: Parkinson Disease; Virtual Reality Therapy; Functional Magnetic Resonance Imaging
Interventions: Behavioral: Virtual Reality; Behavioral: Exercise Therapy; Drug: Pharmacological Treatment
Sponsor: Farzin Hajebrahimi, PT, MSc
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: University of Rochester; Biogen
Recruiting - Condition: Parkinson Disease
Interventions: Device: Adaptive DBS; Device: Conventional DBS
Sponsors: St. George's Hospital, London; University of Oxford
Not yet recruiting - Conditions: Parkinson Disease; REM Sleep Behavior Disorder
Intervention: Other: MRI
Sponsor: Oregon Health and Science University
Recruiting - Condition: Parkinson Disease
Interventions: Other: Rock Steady Boxing; Other: PD SAFEx
Sponsor: Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Recruiting - Conditions: Parkinson Disease; Brain Stimulation; Cerebellum
Interventions: Device: Transcranial direct current stimulation at 2 mA; Device: Transcranial direct current stimulation at 4 mA; Device: Sham transcranial direct current stimulation
Sponsor: Craig Workman
Not yet recruiting - Conditions: Parkinson's Disease; Obstructive Sleep Apnea
Interventions: Device: auto-adjusting positive airway pressure; Other: Nasal dilator strips
Sponsors: McGill University Health Centre/Research Institute of the McGill University Health Centre; Canadian Institutes of Health Research (CIHR); American Thoracic Society
Recruiting - Conditions: Parkinson Disease; PET; MRI
Intervention:
Sponsor: Taipei Veterans General Hospital, Taiwan
Not yet recruiting - Conditions: REM Sleep Behavior Disorder; Pre-motor Parkinson Disease; Symptomatic Parkinson Disease
Intervention: Drug: Carvedilol
Sponsor: Michele Tagliati, MD
Recruiting - Conditions: Parkinson Disease; Healthy
Interventions: Other: Parkinson's disease patients; Other: No drug
Sponsor: Universidade Federal de Pernambuco
Recruiting - Condition: Parkinson's Disease
Interventions: Device: Transcranial Direct Current Stimulation (tDCS); Other: locomotor training; Other: sham-tDCS
Sponsor: University of Miami
Recruiting - Condition: Parkinson Disease
Intervention:
Sponsors: Massachusetts General Hospital; Northwestern University; Sage Bionetworks; University of Rochester; National Institute of Neurological Disorders and Stroke (NINDS); Michael J. Fox Foundation for Parkinson's Research; The Parkinson Study Group
Recruiting - Condition: Parkinson's Disease (PD)
Intervention:
Sponsor: AbbVie
Recruiting - Condition: Idiopathic Parkinson Disease
Intervention: Combination Product: CTC-413
Sponsor: Chase Therapeutics Corporation
Recruiting - Conditions: Parkinson's Disease; Obstructive Sleep Apnea
Interventions: Drug: Sinemet CR; Drug: Placebo oral capsule
Sponsors: McGill University Health Centre/Research Institute of the McGill University Health Centre; Weston Brain Institute
Recruiting - Conditions: Parkinson Disease; Cognitive Dysfunction; Biomarkers
Intervention: Diagnostic Test: serum alpha synuclein autoantibodies, motor and non motor scales
Sponsor: Ain Shams University
Not yet recruiting - Condition: Parkinson Disease
Intervention: Behavioral: CBT group
Sponsor: New York Institute of Technology
Recruiting - Conditions: Early Onset Parkinson Disease; Early Stage Parkinson Disease
Interventions: Other: Game based dual-task training; Other: Treadmill training
Sponsor: National Yang Ming University
Not yet recruiting - Condition: Parkinson's Disease
Intervention: Device: transcranial direct current stimulation (tDCS)
Sponsor: Inje University
Recruiting - Conditions: Parkinson Disease; Dementia; Mild Cognitive Impairment
Interventions: Other: Exoskeleton exercise; Other: Standard exercise; Other: No treatment
Sponsors: Baycrest; Centre for Aging and Brain Health Innovation; University of New Brunswick
Recruiting - Clinical Characteristics of Parkinson's Disease Subjects With Severe Hypertension During Motor OFFs.Conditions: Parkinson Disease; Hypertension; Antiparkinsonism Drugs Causing Adverse Effects in Therapeutic Use
Intervention: Other: No Intervention
Sponsor: Oregon Health and Science University
Recruiting - Conditions: Parkinson's Disease; Gastroparesis; Constipation
Interventions: Drug: RQ-00000010; Drug: Placebo
Sponsors: Virginia Commonwealth University; Michael J. Fox Foundation for Parkinson's Research; RaQualia Pharma Inc.
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Apomorphine; Drug: Dopaminergic Agonist + Apomorphine
Sponsor: Rennes University Hospital
Recruiting - Conditions: Parkinson's Disease; Drug-induced Parkinsonism
Intervention: Behavioral: Exercise
Sponsors: VA Office of Research and Development; University of Pennsylvania
Recruiting - Conditions: Parkinson Disease; Movement Disorders; Neuro-Degenerative Disease
Interventions: Other: Golf Instruction; Other: Tai Chi Class
Sponsor: Massachusetts General Hospital
Recruiting - Conditions: Parkinson's Disease; Mild Cognitive Impairment
Intervention: Device: MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)
Sponsor: VA Office of Research and Development
Not yet recruiting - Condition: Parkinson Disease
Intervention: Procedure: DaTSCAN SPECT/CT in VERITON-CT camera
Sponsor: Central Hospital, Nancy, France
Not yet recruiting - Condition: Parkinson's Disease
Interventions: Behavioral: Facility-based structured exercise; Behavioral: Home-based structured exercise; Behavioral: Health education
Sponsor: VA Office of Research and Development
Not yet recruiting - Condition: Parkinson Disease
Intervention: Procedure: Biofluid samplings
Sponsors: Michael J. Fox Foundation for Parkinson's Research; University Health Network, Toronto; Indiana University; Clinical Trials Coordination Center
Recruiting - Conditions: Parkinson Disease; Neurologic Manifestations
Intervention: Device: Exablate Bilateral Subthalamotomy
Sponsor: InSightec
Recruiting - Conditions: Alzheimer's Disease; Parkinson's Disease; Frontotemporal Lobar Degeneration
Intervention: Behavioral: Observational Study
Sponsor: University Health Network, Toronto
Recruiting - Conditions: Parkinson's Disease; Deep Brain Stimulation; Postoperativeneurocognitive Deficit; Postoperative Delirium
Intervention:
Sponsor: Charite University, Berlin, Germany
Recruiting - Conditions: Parkinson's Disease; Stroke
Interventions: Other: Dual-task training; Other: Treadmill training
Sponsor: National Yang Ming University
Recruiting - Conditions: Aging; Parkinson Disease
Interventions: Device: Medx Console System; Device: Sham Medx Console System; Device: Vielight 810 intranasal stand alone unit; Device: Sham Vielight 810 intranasal stand alone unit
Sponsors: University of Florida; McKnight Brain Research Foundation; University of Arizona
Not yet recruiting - Conditions: Parkinson's Disease; Falls; Balance; Urinary Bladder Diseases
Intervention:
Sponsor: T.C. ORDU ÜNİVERSİTESİ
Recruiting - Primary Parkinsonian Pain Diagnostic Questionnaire: Development and Validation of This QuestionnaireCondition: Parkinson Disease
Intervention: Diagnostic Test: Self-questionnaire 3PDQ
Sponsor: University Hospital, Toulouse
Recruiting - Condition: Parkinson's Disease
Intervention: Device: Deep Brain Stimulation (DBS)
Sponsor: Boston Scientific Corporation
Recruiting - Condition: Parkinson Disease
Intervention: Procedure: Lumbar Puncture
Sponsors: Michael J. Fox Foundation for Parkinson's Research; University Health Network, Toronto; Indiana University; Clinical Trials Coordination Center
Recruiting - Conditions: Parkinson Disease; Constipation; Gastro-Intestinal Disorder
Intervention: Diagnostic Test: Gastrointestinal and Parkinson's Disease
Sponsors: Augusta University; Parkinson's Disease Foundation
Recruiting - Conditions: Parkinson Disease; Dystonia; Autonomic Dysreflexia
Intervention: Other: osteopathic manual therapy
Sponsor: New York Institute of Technology
Recruiting - Conditions: Parkinson Disease; Surgery; Respiration; Decreased; Muscle Weakness
Intervention: Device: MIP and MEP
Sponsor: Mustafa Kemal University
Recruiting - Conditions: Alzheimer's Disease; Lewy Body Dementia; Parkinson's Disease
Interventions: Radiation: DaTscan; Radiation: F18-AV-45; Radiation: FDG-PET; Genetic: APOE genotype; Procedure: Polysomnogram; Behavioral: Clinical Assessment
Sponsors: Douglas Scharre; Avid Radiopharmaceuticals; Mangurian Foundation
Recruiting - Conditions: Parkinson Disease; Virtual Reality; Gait Disorders, Neurologic; Long Range Autocorrelations
Intervention: Device: Virtual reality headset
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Recruiting - Conditions: Parkinson Disease; Neurologic Disorder
Intervention: Device: Brain Tissue Imprint
Sponsor: University Hospital, Grenoble
Not yet recruiting - Conditions: Depression; Mood; Burden, Dependency
Intervention: Behavioral: Group piano training
Sponsor: University of Miami
Recruiting - Conditions: Dysphagia; Parkinson Disease; Swallowing Disorder.Other Specified; Brain Diseases
Intervention: Device: repetitive magnetic stimulation
Sponsors: University of Manchester; Salford Royal NHS Foundation Trust
Recruiting - RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's DiseaseConditions: Essential Tremor; Parkinson Disease
Intervention: Device: Unframed Virtual Cone
Sponsor: University of Alabama at Birmingham
Recruiting - Condition: Parkinson Disease
Intervention: Diagnostic Test: Blood Assayed for CTCs
Sponsor: NYU Langone Health
Not yet recruiting - Condition: Parkinson Disease
Interventions: Device: Open Loop DBS (Summit RC+S); Device: Adaptive (Closed Loop) DBS (Summit RC+S); Device: Intermittent Open Loop DBS (Summit RC+S)
Sponsor: Stanford University
Recruiting - Condition: Parkinson Disease
Interventions: Other: reading a table format prescription on a touch screen; Other: reading a textual format prescription on a touch screen; Other: filling a virtual pillbox displayed on the screen as prescribed in the prescription; Other: eye-tracker; Other: cognitive tests and questionary
Sponsor: Centre Hospitalier Universitaire, Amiens
Recruiting - Condition: Parkinson Disease
Interventions: Other: The role of the noradrenergic system across the life span (Healthy Subjects); Other: The role of the noradrenergic system across the life span (Parkinson's Disease Subjects)
Sponsor: Hospices Civils de Lyon
Recruiting - Condition: Parkinson Disease
Interventions: Drug: Memantine; Other: Placebo
Sponsor: Wayne State University
Not yet recruiting - Condition: Parkinson Disease
Interventions: Drug: Ongentys; Drug: BIA 9-1067 (test)
Sponsor: Bial - Portela C S.A.
Not yet recruiting - Condition: Parkinson Disease
Intervention: Procedure: Personalized DBS adjustments
Sponsor: Darlene Floden
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: KW-6356; Drug: Clarithromycin; Drug: Rifampicin
Sponsor: Kyowa Kirin Co., Ltd.
Recruiting - Condition: Parkinson Disease
Intervention: Procedure: Transcranial direct current stimulation
Sponsor: Universidade Federal do Piauí
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: XC130-A10H; Drug: Placebo
Sponsors: Xoc Pharmaceuticals; Celerion
Recruiting - Condition: Parkinson Disease
Interventions: Drug: LY03003; Drug: Neupro 4Mg/24Hr Transdermal Patch
Sponsor: Luye Pharma Group Ltd.
Recruiting - Conditions: Gait Disorders, Neurologic; Parkinson Disease
Intervention: Device: Carbon Fiber Ankle Foot Orthosis (AFO)
Sponsors: University of Texas Southwestern Medical Center; American Orthotic and Prosthetic Association
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: KW-6356 Low Dose; Drug: KW-6356 Middle Dose; Drug: KW-6356 High Dose; Drug: KW-6356 X Dose; Drug: KW-6356 Y Dose; Drug: Placebo
Sponsor: Kyowa Kirin Co., Ltd.
Recruiting - Condition: Parkinson Disease
Interventions: Device: biphasic stimulation; Device: standard stimulation; Device: Uniform distribution; Device: Poisson distribution; Device: Recordings of LFP oscillations
Sponsor: Colette Boex
Recruiting - Condition: Parkinson's Disease
Intervention: Drug: Rasagiline
Sponsor: Takeda
Recruiting - Condition: Parkinson's Disease
Intervention: Other: Detailed motor testing, including FoG, in PD subjects
Sponsors: VA Office of Research and Development; University of Michigan
Recruiting - Condition: Parkinson's Disease
Intervention: Drug: Exenatide
Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Idiopathic Parkinson's Disease
Interventions: Drug: PD patients H&Y=1.5-2 Medications ON; Drug: PD patients H&Y=1.5-2 Medications OFF; Behavioral: Healthy age-matched controls; Drug: PD patients H&Y=3 Medications OFF; Drug: PD patients H&Y=3 Medications ON
Sponsor: Giovanni Mirabella
Not yet recruiting - Condition: Parkinson Disease
Intervention: Device: Vercise Deep Brain Stimulation System
Sponsor: Boston Scientific Corporation
Recruiting - Condition: Parkinson's Disease
Interventions: Drug: MEDI1341; Drug: Placebo
Sponsors: AstraZeneca; Covance; MMS Holdings, Inc; Catalent
Recruiting - Condition: Parkinson Disease
Intervention: Device: Algorithm based programming using Kinesia-based assessment
Sponsors: Great Lakes NeuroTechnologies Inc.; Atrium Health; Ohio State University; Wake Forest University
Recruiting - Condition: Parkinson's Disease
Interventions: Device: iPad-Based Clinical Support Care; Other: Standard Clinical Care
Sponsors: University of Utah; University of Florida; National Institute of Nursing Research (NINR); Wake Forest University Health Sciences; Baylor College of Medicine; NYU; University of California, San Francisco
Recruiting - Conditions: Parkinson Disease; Physical Activity; Gait Disorders, Neurologic; Neural Degeneration
Interventions: Behavioral: HiBalance; Behavioral: Speech and communication therapy
Sponsors: Karolinska Institutet; Karolinska University Hospital
Recruiting - Conditions: Parkinson Disease; Multiple System Atrophy
Intervention: Other: Biomarker assay
Sponsor: Stony Brook University
Recruiting - Conditions: Parkinson Disease; PARK1; PARK2
Intervention:
Sponsors: King's College London; King's College Hospital NHS Trust; Michael J. Fox Foundation for Parkinson's Research
Not yet recruiting - Condition: Parkinson Disease (PD)
Interventions: Other: Doorway Width Test; Other: Door Frame Color Test
Sponsor: University of Florida
Recruiting - Condition: Parkinson's Disease (PD)
Intervention: Device: New Programming Paradigm
Sponsor: Boston Scientific Corporation
Recruiting - Condition: Parkinson Disease
Intervention: Device: [18F]T807 (also known as 18F-AV- 1451)
Sponsors: University of Pennsylvania; Avid Radiopharmaceuticals
Recruiting - Conditions: Parkinson Disease; Movement Disorders; Neurodegenerative Diseases; Nervous System Diseases; Brain Diseases
Interventions: Drug: Cerebral Dopamine Neurotrophic Factor; Device: Renishaw Drug Delivery System
Sponsors: Herantis Pharma Plc.; Renishaw plc.
Recruiting - Condition: Parkinson Disease With Freezing of Gait
Intervention: Radiation: transcranial magnetic stimulation
Sponsor: Medical University of South Carolina
Recruiting - Condition: Wolff-Parkinson-White Syndrome
Intervention: Procedure: Electrophysiology testing and exercise stress testing
Sponsor: Karolinska University Hospital
Recruiting - Conditions: Parkinson Disease; Movement Disorders; Neuro-Degenerative Disease; Nervous System Diseases; Brain Diseases
Interventions: Drug: Cerebral Dopamine Neurotrophic Factor; Device: Renishaw Drug Delivery System
Sponsors: Herantis Pharma Plc.; Renishaw plc.
Recruiting - Conditions: Parkinson Disease; Oral Infection
Intervention: Behavioral: Oral education
Sponsor: Rennes University Hospital
Not yet recruiting - Conditions: Central Nervous System Disease; Basal Ganglia Disease; Movement Disorders; Neurodegenerative Disorders; Parkinson Disease
Interventions: Procedure: Deep brain stimulation (DBS) of Globus Pallidus internus (GPi) and Best medical treatment (BMT); Procedure: Best medical treatment
Sponsors: University Hospital Inselspital, Berne; Boston Scientific Corporation
Recruiting - Conditions: Parkinson Disease; Depression; Sleep Disorders; Circadian Rhythm Disorders
Intervention: Drug: Agomelatine or PIacebo
Sponsor: Second Affiliated Hospital of Soochow University
Not yet recruiting - Conditions: Primary Parkinsonism; Rehabilitation; Kinematics; Gait Disorders, Neurologic
Interventions: Other: Mental and Physical Practice; Other: Physical Practice
Sponsor: Universidade Federal do Rio Grande do Norte
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Healthy Volunteers
Intervention: Drug: [18F]MNI-1126
Sponsor: Invicro
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease
Intervention: Behavioral: Cognitive tests
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Observation
Intervention:
Sponsors: Ain Shams University; Al-Azhar University
Recruiting - Condition: Dyskinesias
Interventions: Drug: JM-010 A group; Drug: JM-010 B group; Drug: Placebos
Sponsors: Contera Pharma; Bukwang Pharmaceutical
Not yet recruiting - Condition: Insomnia
Interventions: Drug: Suvorexant; Drug: Placebo
Sponsors: Burdick, Daniel, M.D.; Merck Sharp & Dohme Corp.
Recruiting - Conditions: Parkinson Disease; Deep Brain Stimulation
Intervention: Behavioral: sessions of sophrology
Sponsor: Rennes University Hospital
Recruiting - Conditions: Parkinson Disease; Multiple System Atrophy; REM Sleep Behavior Disorder; Pure Autonomic Failure; Dementia With Lewy Bodies
Intervention:
Sponsors: NYU Langone Health; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Conditions: Parkinson Disease; Multiple Sclerosis; Stroke
Interventions: Device: Low-Fidelity PDS; Device: High Fidelity Fixed-Base Simulator
Sponsor: University of Kansas Medical Center
Not yet recruiting - Conditions: Parkinson Disease; Parkinsonism; Lewy Body Disease; Supranuclear Palsy, Progressive; Parkinsonism Vascular; Multiple System Atrophy; Corticobasal Degeneration
Intervention: Behavioral: Palliative Care
Sponsors: University of Colorado, Denver; National Institute of Nursing Research (NINR); University of California, San Francisco
Recruiting - Condition: REM Sleep Behavior Disorder
Intervention: Diagnostic Test: Colonoscopy
Sponsor: Chinese University of Hong Kong
Recruiting - Conditions: Hepatitis C; Hepatitis B; Parkinson Disease
Intervention: Drug: 18F-DOPA PET
Sponsor: National Taiwan University Hospital
Recruiting - Condition: Lewy Body Dementia
Interventions: Drug: LY3154207; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Conditions: Parkinson Disease; Inflammation
Intervention: Drug: Rifaximin 550 MG
Sponsor: Taipei Medical University Shuang Ho Hospital
Recruiting - Conditions: Neuroscience; Movement Disorders
Intervention: Other: Neurophysiological assessment
Sponsor: Neuromed IRCCS
Not yet recruiting - Conditions: Essential Tremor; Parkinson's Disease
Intervention: Device: Clinician programmer electrode screening mode tool
Sponsor: Abbott Medical Devices
Recruiting - Conditions: Parkinson Disease; Cognitive Impairment
Intervention:
Sponsor: University of Washington
Recruiting - Conditions: Parkinson Disease; Essential Tremor; Dystonia
Intervention: Device: Deep Brain Stimulation
Sponsors: Washington University School of Medicine; National Institute for Biomedical Imaging and Bioengineering (NIBIB); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Parkinson
Intervention: Device: DBS
Sponsors: Abbott Medical Devices; Baylor College of Medicine; University of Houston
Recruiting - Conditions: Parkinson Disease (PD); Paralysis; Supranuclear
Intervention: Other: 3D gait analysis
Sponsor: IRCCS San Raffaele
Recruiting - Condition: Parkinsonian Disorders
Interventions: Other: V1: HGPO + meal and V2: placebo + meal; Other: V1: placebo 75mg + meal and V2: HGPO 75mg + meal
Sponsors: University Hospital, Toulouse; Ministry of Health, France
Recruiting - Conditions: Parkinson Disease; REM Behavior Disorder
Intervention: Other: Sleep, PD and DBS
Sponsor: University of Colorado, Denver
Recruiting - Conditions: Parkinson Disease; Restless Leg Syndrome
Intervention: Behavioral: Diary (for reporting all impulse control disorders especially compulsive eating disorders)
Sponsor: University Hospital, Clermont-Ferrand
Not yet recruiting - Conditions: Dyskinesia, Drug-Induced; Parkinson Disease
Interventions: Drug: Safinamide Methanesulfonate 150mg; Drug: Safinamide Methanesulfonate 100mg; Drug: Safinamide Methanesulfonate matching placebo
Sponsor: Zambon SpA
Not yet recruiting - Conditions: Essential Tremor; Parkinson's Disease
Interventions: Procedure: Deep brain stimulation implantation surgery; Device: Ad-Tech Medical Instrumentation Corp. device; Device: FHC Guideline 4000+ system
Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Aging; Emotions; Parkinson Disease
Interventions: Behavioral: Anterior insula cortex activation; Behavioral: Primary auditory cortex activation
Sponsors: University of Florida; National Institute on Aging (NIA)
Recruiting - Conditions: Parkinson's Disease; Tremor; Dystonia
Intervention: Other: Feed-back controlled deep brain stimulation
Sponsor: University of Oxford
Not yet recruiting - Conditions: Parkinson Disease; Dystonia; Essential Tremor
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Parkinson Disease; Multiple Sclerosis; Trauma, Brain
Intervention:
Sponsor: T.C. ORDU ÜNİVERSİTESİ
Not yet recruiting - Conditions: Parkinson Disease; Essential Tremor; Dystonia
Intervention: Device: Deep Brain Stimulation
Sponsor: Boston Scientific Corporation
Recruiting - Conditions: Parkinson's Disease; Dyskinesias; Movement Disorders
Interventions: Drug: Buspirone; Drug: Placebo
Sponsors: Oregon Health and Science University; Portland VA Medical Center
Recruiting - Conditions: Parkinson's Disease; Multiple System Atrophy; Autonomic Failure
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Parkinson's Disease; Essential Tremor; Dystonia
Intervention: Procedure: Deep Brain Stimulation
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Parkinson Disease; Tremor, Essential; Dystonia, Primary
Intervention: Procedure: Hypnosis
Sponsor: University Hospital, Geneva
Recruiting - Conditions: Essential Tremor; Parkinson Disease; Dystonia
Interventions: Device: Active biphasic pulse stimulation---Home Settings; Device: Active biphasic pulse stimulation---VIN Biphasic; Device: Active biphasic pulse stimulation---Stimulator Off
Sponsors: University of Florida; National Institutes of Health (NIH)
Not yet recruiting - Conditions: Functional Movement Disorder; Parkinson Disease; Dystonic Disorders
Intervention: Other: Self-questionnaire YSQ-S3 (Young Schema Questionnaire)
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - Conditions: Amyotrophic Lateral Sclerosis; Parkinson Disease; Dysphagia
Interventions: Diagnostic Test: Videofluoroscopic Swallowing Examination; Other: Tongue Strength Measurement
Sponsors: University Health Network, Toronto; University of Florida; National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - Conditions: Parkinson Disease; Obsessive-Compulsive Disorder; Epilepsy; Depression
Intervention: Other: electrophysiological data from DBS
Sponsor: University Hospital, Grenoble
Recruiting - Conditions: Parkinson Disease (PD); Chronic Heart Failure (CHF); Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Behavioral: SIDERA^B; Behavioral: Usual Care Program
Sponsors: Fondazione Don Carlo Gnocchi Onlus; Università Carlo Cattaneo , Castellanza; University of Milano Bicocca
Not yet recruiting - Conditions: Parkinsonian Syndromes; Parkinson's Disease; Multiple System Atrophy; Progressive Supranuclear Palsy
Interventions: Other: CSF, blood and urine sampling; Other: clinical measures of disease severity and progression
Sponsor: University Hospital, Bordeaux
Recruiting - Conditions: Tremor; Essential Tremor; Parkinson Disease; Radiosurgery; Quality of Life
Intervention: Other: Questionnaires / Observational Assessments
Sponsor: Vanderbilt University Medical Center
Recruiting - Conditions: Parkinson's Disease; Essential Tremor; Dystonia; Obsessive Compulsive Disorder
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Conditions: Apathy; Frontotemporal Dementia; Parkinson Disease; Depressive Symptoms
Interventions: Behavioral: ECOCAPTURE; Behavioral: Cognitive and Behavioral experimental tasks; Diagnostic Test: Neuropsychological assessment; Behavioral: ICM_APATHY_TASKS; Other: MRI; Biological: Neurohormonal mechanisms; Diagnostic Test: Supplementary Neuropsychological Assessment - Parkinson's Disease
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - Condition: TMS Protocols in the Treatment of PD
Intervention: Device: repetitive transcranial magnetic stimulation(rTMS)
Sponsor: Guangdong General Hospital
Recruiting - Conditions: Healthy Volunteer; Alzheimer Disease; Frontotemporal Dementia; Parkinson Disease
Intervention: Drug: [18F]PI-2620
Sponsors: Asan Medical Center; Korea Health Industry Development Institute
Recruiting - Conditions: Parkinson Disease; Essential Tremor; Movement Disorders; Parkinson's Syndrome; Atypical Parkinsonism
Intervention: Other: Data Capture
Sponsor: Westfälische Wilhelms-Universität Münster
Recruiting - Conditions: Multiple Sclerosis; Parkinson Disease; Amyotrophic Lateral Sclerosis; Alzheimer Disease
Intervention: Procedure: lumbar puncture
Sponsors: Neuromed IRCCS; IRCCS Multimedica
Recruiting - Conditions: Parkinson Disease; Dystonia; Depression; Spinal Stenosis; Spinal Diseases
Intervention: Diagnostic Test: MRI of the spine
Sponsor: University Health Network, Toronto
Recruiting - Conditions: Parkinson Disease; Dystonia; Tremors; Obsessive Compulsive Disorder; Depression
Intervention: Other: No intervention
Sponsor: Ohio State University
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Vascular Cognitive Impairment; Parkinson's Disease; Lewy Body Disease
Intervention: Other: Flutemetamol PET scan
Sponsors: Sunnybrook Health Sciences Centre; Brain Canada; Weston Brain Institute; GE Healthcare; University Health Network, Toronto; Centre for Addiction and Mental Health; Baycrest; St. Michael's Hospital, Toronto; Kensington Eye Institute
Recruiting - Conditions: Cardiomyopathy; Li-Fraumeni Syndrome; Parkinson's Disease; Atherosclerosis; Cardiovascular Capacity
Intervention:
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - Conditions: Parkinson's Disease; Movement Disorders; Deep Brain Stimulation; Dystonia; Essential Tremor
Intervention: Other: Deep Brain Stimulation Management
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Conditions: Movement Disorders; Parkinson Disease; Essential Tremor; Tremor; Dystonia
Intervention: Procedure: MRI imaging procedure
Sponsor: Abbott Medical Devices
Recruiting - Conditions: Amyotrophic Lateral Sclerosis (ALS); Myasthenia Gravis; Myopathies; Stroke; Parkinson's Disease
Intervention:
Sponsor: Beth Israel Deaconess Medical Center
Recruiting - Conditions: Anomia; Stroke; Aphasia; Parkinson Disease; Multiple Sclerosis
Interventions: Behavioral: Semantic feature analysis; Behavioral: Comprehension training
Sponsors: Göteborg University; The Swedish Research Council; Swedish Council for Working Life and Social Research
Recruiting - Conditions: Schizophrenia; Autism Spectrum Disorder; Bipolar Disorder; Depression; Parkinson Disease
Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS); Device: Sham Repetitive Transcranial Magnetic Stimulation (rTMS)
Sponsor: Krystal Parker, PhD
Recruiting - Conditions: Parkinson's Disease; Obsessive Compulsive Disorder; Dystonia; Essential Tremor; Epilepsy
Intervention: Device: Stereotactic brain procedures
Sponsors: Vanderbilt University Medical Center; National Institute for Biomedical Imaging and Bioengineering (NIBIB); National Institute of Neurological Disorders and Stroke (NINDS); National Institute of Mental Health (NIMH)
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Frontal Dementia; Huntington Disease; Traumatic Brain Injury; Stroke
Intervention: Behavioral: social cognition
Sponsor: Centre Hospitalier Universitaire, Amiens
Recruiting - Conditions: Progressive Supranuclear Palsy; Dementia With Lewy Bodies; Multiple System Atrophy; Corticobasal Syndrome; Atypical Parkinson Disease
Interventions: Behavioral: Home Visit Program; Behavioral: Usual Care/Online Survey
Sponsor: Rush University Medical Center
Recruiting - Conditions: Autonomic Failure; Pure Autonomic Failure; Multiple System Atrophy; Parkinson Disease; Orthostatic Hypotension
Interventions: Drug: Droxidopa; Drug: Midodrine; Drug: Placebo
Sponsor: Vanderbilt University Medical Center
Recruiting - Conditions: REM Sleep Behavior Disorder; Parkinson Disease; Lewy Body Disease; Dementia With Lewy Bodies; Multiple System Atrophy; REM Sleep Parasomnias
Intervention:
Sponsors: Washington University School of Medicine; Mayo Clinic; University of Minnesota - Clinical and Translational Science Institute; University of California, Los Angeles; McGill University; Emory University; Massachusetts General Hospital; National Institute on Aging (NIA)
Recruiting - Conditions: Parkinson's Disease; Parkinsonian Disorders; Atypical Parkinson Disease; Progressive Supranuclear Palsy; Multiple System Atrophy; Corticobasal Degeneration; Gait, Frontal
Interventions: Drug: Anti-Parkinson medication; Device: Deep Brain Stimulation
Sponsor: Beth Israel Deaconess Medical Center
Recruiting - Conditions: Ataxia; Dystonia; Parkinson's Disease; Amyotrophic Lateral Sclerosis; Corticobasal Degeneration; Multiple System Atrophy; Alzheimer's Disease; Lewy Body Dementia; Parkinson Disease-Dementia; Dentatorubral-pallidoluysian Atrophy; Creutzfeldt-Jakob Disease and Fatal Familial Insomnia; Fragile X-associated Tremor/Ataxia Syndrome; Krabbe's Disease; Niemann-Pick Disease, Type C; Neuronal Ceroid Lipofuscinosis
Intervention:
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: the Elderly
Intervention: Behavioral: tests
Sponsor: University Hospital, Strasbourg, France
Recruiting - Conditions: Alzheimer Disease (AD); Frontotemporal Lobar Degeneration; Dementia With Lewy Bodies (DLB); Parkinson Disease Dementia (PDD); Progressive Supranuclear Palsy (PSP); Corticobasal Degeneration (CBD)
Intervention:
Sponsors: Amoneta Diagnostics SAS; European Commission; Firalis SA; University Hospital, Strasbourg; Centre Hospitalier Universitaire Vaudois; IRCCS Centro San Giovanni di Dio Fatebenefratelli; Hôpitaux Civils de Colmar; Istanbul University; Assistance Publique - Hôpitaux de Paris; University Hospital, Lille; University Hospital, Geneva; Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Erasme University Hospital; University Hospital, Montpellier; Centre Hospitalier Universitaire de Besancon; Centre Hospitalier Universitaire de Nice
Recruiting - Conditions: Parkinson Disease; Stroke; Multiple Sclerosis; Gait Disorders, Neurologic; Gait Disorder, Sensorimotor; Gait, Unsteady; Gait Ataxia; Gait, Stumbling; Gait, Shuffling
Interventions: Other: Feedback-assisted physical therapy; Other: Traditional physical therapy
Sponsors: Oregon Health and Science University; NorthWest Rehabilitations Associates; APDM
Recruiting - Conditions: Movement Disorders; Parkinson Disease; Essential Tremor; Tremor; Dystonia; Primary Dystonia; Secondary Dystonia
Intervention: Device: Deep Brain Stimulation (DBS)
Sponsor: Abbott Medical Devices
Not yet recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Retinal Vascular; Parkinson Disease; Multiple Sclerosis; Huntington Disease; Neuro-Degenerative Disease
Intervention: Device: Retinal Imaging
Sponsors: Duke University; Alzheimer’s Drug Discovery Foundation; University of Edinburgh
Recruiting - Conditions: Dementia; Parkinson Disease; Pulmonary Hypertension; Heart Diseases; Paget Disease; Bone Diseases; Bone Fracture; Renal Disease; Pulmonary Embolism; Bone Lesion
Intervention: Device: CZT SPECT imaging
Sponsors: Spectrum Dynamics; University Hospital, Caen
Recruiting - Conditions: Spinal Cord Injuries; Traumatic Brain Injury; Spina Bifida; Cerebral Palsy; Stroke; Parkinson Disease; Multiple Sclerosis
Intervention: Other: Movement-2-Music (M2M)
Sponsors: University of Alabama at Birmingham; Lakeshore Foundation; YMCA of Greater Birmingham
Recruiting - Conditions: Movement Disorders; Essential Tremor; Holmes Tremor; Parkinson's Disease; Wilson's Disease; Huntington's Disease; Dystonia; Tardive Dyskinesia; Orofacial Dyskinesias
Intervention: Device: Transcranial ExAblate System
Sponsor: InSightec
Recruiting - Conditions: ALS; Autism Spectrum Disorder; Cancer; Spasticity, Muscle; Dyskinetic Syndrome; Epilepsy; Glaucoma; Huntington Disease; Inflammatory Bowel Disease (IBD); Multiple Sclerosis; Neuropathy; Opioid Use; Parkinson Disease; HIV/AIDS; Ptsd; Intractable Pain; Sickle Cell Disease; Terminal Illness
Interventions: Other: Registry; Other: PK microsampling of blood
Sponsors: Children's Hospital of Philadelphia; Ilera Healthcare
Recruiting - Conditions: Patients With Synucleinopathies; Neurogenic Orthostatic Hypotension; Pure Autonomic Failure; REM Sleep Behavior Disorder; Parkinson Disease; Dementia With Lewy Bodies; Multiple System Atrophy; Shy-Drager Disease
Intervention:
Sponsor: NYU Langone Health
Recruiting - Conditions: Chronic Pain; Chronic Pain Syndrome; Chronic Pain Due to Injury; Chronic Pain Due to Trauma; Fibromyalgia; Seizures; Hepatitis C; Cancer; Crohn Disease; HIV/AIDS; Multiple Sclerosis; Traumatic Brain Injury; Sickle Cell Disease; Post Traumatic Stress Disorder; Tourette Syndrome; Ulcerative Colitis; Glaucoma; Epilepsy; Inflammatory Bowel Diseases; Parkinson Disease; Amyotrophic Lateral Sclerosis; Chronic Traumatic Encephalopathy; Anxiety; Depression; Insomnia; Autism; Opioid-use Disorder; Bipolar Disorder
Intervention: Drug: Cannabis, Medical
Sponsor: OMNI Medical Services, LLC
Recruiting - Conditions: Coronary Heart Disease; Anemia; Bronchial Asthma; Stroke; Epilepsy; Parkinson's Disease; Heart Rhythm Disorders; Alzheimer's Disease; Neuromuscular Diseases; Diabetes; Chronic Heart Failure; Chronic Obstructive Pulmonary Disease; Chronic Kidney Diseases
Intervention:
Sponsors: Russian Federation of Anesthesiologists and Reanimatologists; Kuban State Medical University
Recruiting - Conditions: Mild Cognitive Impairment (MCI); Alzheimer Disease (AD); Dementia With Lewy Bodies (DLB); Frontotemporal Lobar Degeneration (FTLD); Parkinsons Disease With Dementia (PDD); Transient Epileptic Amnesia (TEA); Temporal Lobe Epilepsy (TLE); Spinocerebellar Ataxias (SCA); HIV Associated Neurocognitive Disorder (HAND); Amyotrophic Lateral Sclerosis (ALS); Primary Lateral Sclerosis (PLS)
Intervention: Other: Neuraceq
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - Conditions: Neurologic Disorders; Nervous System Diseases; Neurodegenerative Diseases; Neurological Disorders; Stroke; Traumatic Brain Injury; Cadasil; Chronic Traumatic Encephalopathy; Cerebral Infarction; Cerebral Ischemia; Cerebral Stroke; Cerebral Hemorrhage; Parkinson; Multi-System Degeneration; MSA - Multiple System Atrophy; Progressive Supranuclear Palsy; ALS; Amyotrophic Lateral Sclerosis; Neuropathy; Diabetic Neuropathies
Interventions: Procedure: Intravenous BMSC; Procedure: Intranasal BMSC
Sponsor: MD Stem Cells
Recruiting - Conditions: Dementia; Parkinson; Altered Behavior in Alzheimer Disease; Demyelinating Autoimmune Diseases, CNS; Demyelinating Sensorimotor Neuropathy; Corticobasal Degeneration
Interventions: Procedure: Microcannula Harvest Adipose; Device: Centricyte 1000; Procedure: Sterile Normal Saline Infusion
Sponsors: Regeneris Medical; Global Alliance for Regenerative Medicine; Robert W. Alexander, MD, FICS; Regeneris Medical Inc
Not yet recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Vascular Dementia; Lewy Body Disease; Lewy Body Dementia With Behavioral Disturbance (Disorder); Dementia, Mixed; Parkinson-Dementia Syndrome; Chronic Traumatic Encephalopathy; Huntington's Dementia; Wernicke Korsakoff Syndrome; Traumatic Brain Injury; Dementia, Multi-Infarct; Autism; Autism Spectrum Disorder; Autistic Behavior; Autistic Disorder, Current or Active State; Cadasil; LATE Limbic-predominant Age-related TDP-43 Encephalopathy
Interventions: Procedure: Intravenous Bone Marrow Stem Cell (BMSC) Fraction; Procedure: Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction; Procedure: Near Infrared Light
Sponsor: MD Stem Cells
Recruiting - Condition: Symptomatic Neurogenic Orthostatic Hypotension
Interventions: Drug: Droxidopa capsules; Drug: Placebo capsules
Sponsor: Lundbeck Northera Ltd.
Recruiting - Condition: Cerebral Oxygenation
Interventions: Other: walking; Other: cognitive task
Sponsor: Centre Hospitalier Régional d'Orléans
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: NPT520-34 (125 mg); Drug: Placebos (125 mg)
Sponsors: Neuropore Therapies Inc.; Celerion
Recruiting - Condition: Tremor, Limb
Intervention: Radiation: Thalamotomy
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Recruiting - Condition: Symptomatic Neurogenic Orthostatic Hypotension
Interventions: Drug: ampreloxetine; Drug: Placebo
Sponsor: Theravance Biopharma
Recruiting - Condition: Symptomatic Neurogenic Orthostatic Hypotension
Interventions: Drug: ampreloxetine; Drug: Placebo
Sponsor: Theravance Biopharma
Recruiting - Condition: Nervous System Disease
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Neurodegenerative Disorders
Intervention:
Sponsor: Hadassah Medical Organization
Recruiting - Conditions: Healthy; Neurodegenerative Disease
Intervention:
Sponsor: University of California, San Francisco
Recruiting - Condition: Neurologic Disorders
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Dementia-related Psychosis
Interventions: Drug: Placebo; Drug: Pimavanserin 34 mg; Drug: Pimavanserin 20 mg
Sponsor: ACADIA Pharmaceuticals Inc.
Recruiting
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