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- Condition: Alzheimer's Disease
Intervention: Drug: ABBV-8E12
Sponsor: AbbVie
Not yet recruiting - Conditions: Alzheimer's Disease; Disruptive Behavior
Interventions: Drug: Prazosin; Drug: Placebo oral capsule
Sponsors: Alzheimer's Disease Cooperative Study (ADCS); National Institute on Aging (NIA); VA Puget Sound Health Care System
Not yet recruiting - Condition: Alzheimer Disease, Early Onset
Intervention: Drug: Sustiva Pill
Sponsors: Case Western Reserve University; University Hospitals Cleveland Medical Center; Massachusetts General Hospital
Not yet recruiting - Condition: Pain
Intervention: Behavioral: Thermal stimulation
Sponsor: University of Aarhus
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Memantine; Drug: Placebo
Sponsor: University of California, San Diego
Not yet recruiting - Conditions: Alzheimer Disease; Olfaction Disorders
Intervention: Diagnostic Test: Olfactory test
Sponsor: Jewish General Hospital
Not yet recruiting - Condition: Tau and Amyloid Aggregation in Racially/Ethnically Diverse Adults
Interventions: Drug: 18F-MK-6240; Drug: 18F-Florbetaben
Sponsors: Adam Brickman; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Cognitive Impairment; Alzheimer Disease
Interventions: Drug: THN 201; Drug: Donepezil; Drug: Placebo
Sponsor: Theranexus
Recruiting - Condition: Alzheimer Disease
Intervention: Other: non ontervention / observational study
Sponsor: Centre Hospitalier Universitaire de Nice
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Inflammation
Intervention: Diagnostic Test: GE180 PET Scan
Sponsors: Aaron Ritter, MD; Jeffrey Cummings, MD; Jessica Caldwell, PhD
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Dietary Supplement: Omega-3 treatment; Dietary Supplement: Placebo
Sponsor: University Hospital, Toulouse
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Frontotemporal Dementia
Interventions: Device: Spectral-Domain Optical Coherence Tomography (SD-OCT); Device: Magnetic Resonance Imaging (MRI); Device: Positron Emission Tomography (PET); Diagnostic Test: Comprehensive Ophthalmic Examination; Device: Fundus Photography
Sponsor: University of Michigan
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Self-Guided Lifestyle Intervention; Behavioral: Structured Lifestyle Intervention
Sponsors: Wake Forest University Health Sciences; Alzheimer's Association
Not yet recruiting - Conditions: Alzheimer Disease; Dementia; Mild Cognitive Impairment; Aging; Aging Disorder
Intervention:
Sponsor: Georgetown University
Recruiting - Conditions: Dementia; Dysphagia
Interventions: Device: Isometric tongue strengthening; Drug: Biotene
Sponsor: University of Wisconsin, Madison
Recruiting - Conditions: Alzheimer Disease; Dementia; Neuropathology; Mild Cognitive Impairment
Interventions: Device: Computerized cognitive battery: Cognigram (CG); Device: The NeuroCatch™ Platform (NCP)
Sponsor: Bruyere Research Institute
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Blood Brain Barrier (BBB) Disruption
Sponsor: InSightec
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Photobiomodulation REGEnLIFE RGn530 device; Device: SHAM REGEnLIFE RGn530 device
Sponsor: University Hospital, Montpellier
Recruiting - Conditions: Delirium; Dementia Alzheimers; Respiratory Failure
Intervention:
Sponsor: Wake Forest University Health Sciences
Not yet recruiting - Condition: Dementia Caregiving
Intervention: Behavioral: Wish Outcome Obstacle Plan
Sponsors: Yale University; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Alzheimer Disease; Familial Alzheimer Disease (FAD)
Intervention:
Sponsors: Capital Medical University; Beijing Tiantan Hospital; Beijing Chao Yang Hospital; Fu Xing Hospital, Capital Medical University; Peking Union Medical College Hospital; Peking University First Hospital; Peking University Third Hospital; Chinese PLA General Hospital; China-Japan Friendship Hospital; Beijing Geriatric Hospital; The First Affiliated Hospital of Dalian Medical University; Fujian Medical University Union Hospital; Guangzhou Psychiatric Hospital; Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; First Affiliated Hospital of Guangxi Medical University; The Affiliated Hospital Of Guizhou Medical University; Handan Central Hospital; Hebei General Hospital; First Hospital of Shijiazhuang City; Tangshan Worker's Hospital; Henan Provincial Hospital; Kaifeng Central Hospital; People's Hospital of Zhengzhou University; First Affiliated Hospital of Harbin Medical University; Tongji Hospital; People's Hospital Affiliated Hubei Medical University; Wuhan University Zhongnan Hospital; The Third Xiangya Hospital of Central South University; Xiangya Hospital of Central South University; First Hospital of Jilin University; China-Japan Union Hospital, Jilin University; Subei People's Hospital of Jiangsu; Nantong University Affiliated Hospital; Mineral General Hospital, Xuzhou; Jiangxi Provincial People's Hopital; Changda Hospital, Anshan; The Affiliated Zhongshan Hospital of Dalian University; First Hospital of China Medical University; Baotou Central Hospital; General Hospital of Ningxia Medical University; The People's Hospital of Ningxia; The Affiliated Hospital of Qingdao University; The 88th Hospital of PLA; Qilu Hospital of Shandong University; Qilu Hospital of Shandong University (Qingdao); Shandong Provincial Hospital; Qingdao Municipal Hospital; The First Affiliated Hospital of Shanxi Medical University; Tang-Du Hospital; First Affiliated Hospital Xi'an Jiaotong University; Ruijin Hospital; RenJi Hospital; Shanghai Changzheng Hospital; Affiliated Hospital of North Sichuan Medical College; Tianjin Huanhu Hospital; Tianjin Medical University General Hospital; Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region; Ningbo Medical Center Lihuili Hospital; First Affiliated Hospital of Wenzhou Medical Univeristy; First Affiliated Hospital of Zhejiang University; Shao Yifu Hospital of Zhejiang Medical University; Zhejiang Provincial People’s Hospital; Daping Hospital and the Research Institute of Surgery of the Third Military Medical University; The Second Affiliated Hospital of Chongqing Medical University; The First Affiliated Hospital of Anhui Medical University; Chongqing People's Hospital; Dongfang Hospital Affiliated to Beijing University of Chinese Medicine; Zigong First People's Hospital
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease
Interventions: Other: tDCS; Other: Exercise; Other: Exercise Education; Other: Sham tDCS
Sponsor: Sunnybrook Health Sciences Centre
Recruiting - Conditions: Alzheimer's Disease; Alzheimer Dementia (AD); Aggression
Interventions: Behavioral: Non-Pharmacological Intervention; Other: Pharmacological Intervention
Sponsors: Centre for Addiction and Mental Health; University of Calgary; Lawson Health Research Institute; Douglas Mental Health University Institute
Not yet recruiting - Conditions: Major Depressive Disorder; Alzheimer Disease
Interventions: Device: Brainsway H1-Coil Deep TMS System (Sham treatment); Device: Brainsway H1-Coil Deep TMS System
Sponsors: Rotman Research Institute at Baycrest; Brainsway; Centre for Addiction and Mental Health
Not yet recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: Personalized care network
Sponsor: University of Washington
Not yet recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: Senior-Companion Dementia Group
Sponsors: University of Minnesota - Clinical and Translational Science Institute; Lutheran Social Services of Minnesota; Johns Hopkins University; Brown University; University of Texas-Arlington
Not yet recruiting - Condition: Mild Cognitive Impairment
Intervention: Device: 18F--MK6240 PET-MRI
Sponsor: New York University School of Medicine
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Cognitive-Behavioral group therapy; Behavioral: Non directive support Group
Sponsors: Dr Sébastien Grenier; Alzheimer Society of Canada; Université de Montréal
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Dementia; Cognition Disorders in Old Age; Cognitive Decline; Cognitive Deterioration
Intervention: Device: Combination of 40Hz light and cognitive therapy (ALZLIFE)
Sponsor: Alzheimer's Light LLC
Recruiting - Conditions: Alzheimer Disease; Amnestic-Mild Cognitive Impairment
Interventions: Diagnostic Test: EEG; Genetic: ApoE
Sponsor: Catholic University of the Sacred Heart
Not yet recruiting - Conditions: Dementia; Alzheimer Disease; Circadian Rhythm Disorders; Circadian Rhythm Sleep Disorder; Insomnia; Hypersomnia; Cognitive Impairment; Cognitive Decline; Mild Cognitive Impairment; Frontotemporal Dementia; Neurocognitive Disorders; Vascular Dementia; Sleep Disorder; Memory Impairment
Interventions: Behavioral: Attention-Control Condition; Behavioral: Timed Activity Intervention
Sponsor: University of Pennsylvania
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Placebo; Drug: LUPRON DEPOT 22.5 mg
Sponsor: New York University School of Medicine
Not yet recruiting - Conditions: Alzheimer Disease; Subjective Cognitive Impairment
Interventions: Other: Doppler ultrasonography; Other: Biospecimen collection
Sponsors: Assistance Publique - Hôpitaux de Paris; Fondation Plan Alzheimer; Naturalia & Biologia
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Genetic: Genetic Testing
Sponsors: Baylor Research Institute; Translational Genomics Research Institute
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: Performing Arts Instruction
Sponsors: Florida Hospital; Dr. Phillips Center for the Performing Arts
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention:
Sponsors: University of Southern California; National Institute on Aging (NIA); Brigham and Women's Hospital; The Cleveland Clinic
Recruiting - Conditions: Cognitive Dysfunction; Alzheimer's Disease
Interventions: Drug: Aducanumab; Drug: Placebo
Sponsor: Biogen
Not yet recruiting - Conditions: Alzheimer Disease, Early Onset; Alzheimer Disease; Alzheimer Dementia; Mild Cognitive Impairment; Memory Disorders; Memory Loss; Memory Impairment; Memory Disorders, Age Related; Alzheimer Disease, Late Onset; Cognitive Impairment; Dementia, Mild; Dementia, Alzheimer Type; Cognitive Decline
Intervention: Device: GammaSense Stimulation System (non-invasive, non-significant risk)
Sponsor: Cognito Therapeutics, Inc.
Recruiting - Conditions: Alzheimer Disease; Early Onset Alzheimer Disease
Intervention: Biological: AAVrh.10hPOE2 vector
Sponsor: Weill Medical College of Cornell University
Not yet recruiting - Conditions: Alzheimer Disease; Dementia Frontal; Mild Cognitive Impairment
Intervention: Device: EEG scan
Sponsors: Metabolic Therapy Inc.; Institute of Asian American Adult Development
Recruiting - Conditions: Autistic Disorders Spectrum; Adhd; Asperger Syndrome; Alzheimer Disease; Parkinson; Tremor Essential; Dementia, Alzheimer Type; Lewy Body Dementia With Behavioral Disturbance (Disorder); Dementia With Lewy Bodies; Dementia Frontal
Intervention:
Sponsor: Rutgers University
Recruiting - Conditions: Dementia; Alzheimer Disease; Mild Cognitive Impairment; Aging; Cognitive Impairment
Intervention: Behavioral: Cognitive Training
Sponsors: University of Leicester; The Dunhill Medical Trust; University Hospitals, Leicester; Leicestershire Partnership Trust; University of Nottingham; Lumosity
Not yet recruiting - Conditions: Healthy; Alzheimer Disease
Interventions: Biological: AL002; Other: Saline Solution
Sponsor: Alector Inc.
Not yet recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease, Late Onset; Familial Alzheimer Disease (FAD); Vascular Cognitive Impairment; APOE Gene Cohort (Cognitive Normal Subjects)
Intervention:
Sponsors: Capital Medical University; Beijing Tiantan Hospital; Beijing Chao Yang Hospital; Fu Xing Hospital, Capital Medical University; Peking Union Medical College Hospital; Peking University First Hospital; Peking University Third Hospital; Chinese PLA General Hospital; China-Japan Friendship Hospital; Beijing Geriatric Hospital; The First Affiliated Hospital of Dalian Medical University; Fujian Medical University Union Hospital; Guangzhou Psychiatric Hospital; Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; First Affiliated Hospital of Guangxi Medical University; The Affiliated Hospital Of Guizhou Medical University; Handan Central Hospital; Hebei General Hospital; First Hospital of Shijiazhuang City; Tangshan Worker's Hospital; Hunan Provincial People's Hospital; Kaifeng Central Hospital; People's Hospital of Zhengzhou University; Wuhan University Zhongnan Hospital; First Affiliated Hospital of Harbin Medical University; Tongji Hospital; People's Hospital Affiliated Hubei Medical University; The Third Xiangya Hospital of Central South University; Xiangya Hospital of Central South University; First Hospital of Jilin University; China-Japan Union Hospital, Jilin University; Subei People's Hospital of Jiangsu; Nantong University Affiliated Hospital; Mineral General Hospital, Xuzhou; Jiangxi Provincial People's Hopital; Changda Hospital, Anshan; The Affiliated Zhongshan Hospital of Dalian University; First Hospital of China Medical University; Baotou Central Hospital; General Hospital of Ningxia Medical University; The People's Hospital of Ningxia; The Affiliated Hospital of Qingdao University; The 88th Hospital of PLA; Qilu Hospital of Shandong University; Qilu Hospital of Shandong University (Qingdao); Shandong Provincial Hospital; Qingdao Municipal Hospital; The First Affiliated Hospital of Shanxi Medical University; Tang-Du Hospital; First Affiliated Hospital Xi'an Jiaotong University; Ruijin Hospital; RenJi Hospital; Shanghai Changzheng Hospital; Affiliated Hospital of North Sichuan Medical College; Tianjin Huanhu Hospital; Tianjin Medical University General Hospital; Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region; Ningbo Medical Center Lihuili Hospital; First Affiliated Hospital of Wenzhou Medical Univeristy; First Affiliated Hospital of Zhejiang University; Shao Yifu Hospital of Zhejiang Medical University; Zhejiang Provincial People’s Hospital; Daping Hospital and the Research Institute of Surgery of the Third Military Medical University; The Second Affiliated Hospital of Chongqing Medical University; The First Affiliated Hospital of Anhui Medical University; Chongqing People's Hospital; Dongfang Hospital Affiliated to Beijing University of Chinese Medicine; Zigong First People's Hospital
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention:
Sponsor: Faroese Hospital System
Recruiting - Conditions: Alzheimer Disease; Presbycusis; Lexical Syntactic Disorder
Intervention: Other: Speech therapy
Sponsor: Groupe Hospitalier de la Rochelle Ré Aunis
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease; Dementia, Vascular; Dementia With Lewy Bodies; Dementia Frontal; Depression; Anxiety
Intervention: Other: Naturalistic observation
Sponsor: Shanghai Mental Health Center
Recruiting - Conditions: Dementia Alzheimers; Dementia; Mild Cognitive Impairment; Dementia, Vascular; Dementia With Lewy Bodies; Cognition Disorders; Neurocognitive Disorders
Intervention: Diagnostic Test: CogCheck
Sponsor: University Hospital, Basel, Switzerland
Not yet recruiting - Condition: Mild to Moderate Alzheimer's Disease
Interventions: Drug: AR1001; Drug: Placebo Oral Tablet
Sponsor: AriBio Co., Ltd.
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Device: DBS-f On; Device: DBS Off
Sponsor: Functional Neuromodulation Ltd
Not yet recruiting - Condition: Alzheimer Disease, Early Onset
Interventions: Drug: AD-35 60mg group; Drug: AD-35 90mg group; Drug: Placebo group
Sponsors: Zhejiang Hisun Pharmaceutical Co. Ltd.; Medpace, Inc.
Recruiting - Condition: Dementia; Alzheimer, Mixed Type (Etiology)
Intervention: Device: Transcranial Direct Current Stimulation
Sponsor: Centre for Addiction and Mental Health
Recruiting - Condition: Agitation Associated With Dementia of the Alzheimer's Type
Interventions: Drug: Brexpiprazole; Drug: Placebo
Sponsor: Otsuka Pharmaceutical Co., Ltd.
Recruiting - Conditions: Alzheimer Disease; Dementia; Neurodegenerative Diseases
Intervention:
Sponsor: Central Hospital, Nancy, France
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Epilepsy; Sleep Wake Disorders
Interventions: Diagnostic Test: scalp EEG and polysomnography; Diagnostic Test: scalp EEG with foramen ovale electrodes with polysomnography
Sponsor: Universitaire Ziekenhuizen Leuven
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: troriluzole; Drug: Placebo oral capsule
Sponsors: Biohaven Pharmaceuticals, Inc.; Alzheimer's Disease Cooperative Study (ADCS)
Recruiting - Condition: Brain DHA Delivery and Alzheimer's Disease Risk
Interventions: Drug: DHA; Drug: Placebo
Sponsors: University of Southern California; Huntington Medical Research Institutes
Recruiting - Conditions: Dementia Alzheimers; Dementia; Dementia, Vascular; Dementia Senile
Intervention:
Sponsor: Moorfields Eye Hospital NHS Foundation Trust
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Behavioral: Dementia-specific advance care planning
Sponsor: University of Lausanne Hospitals
Recruiting - Condition: Dementia
Interventions: Other: Foods consistent with a MDP; Other: Physical Activity; Other: Control
Sponsor: University of East Anglia
Not yet recruiting - Condition: Dementia Alzheimers
Intervention: Radiation: CT scan
Sponsor: Baycrest
Not yet recruiting - Condition: Mild Cognitive Impairment
Intervention: Diagnostic Test: EEG with SPR analysis
Sponsors: Jon Snaedal; Ullevaal University Hospital; Karolinska University Hospital; Rigshospitalet, Denmark; Zealand University Hospital; Haukeland University Hospital; Kavli Research Foundation, Bergen Norway
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: Brexpiprazole
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; H. Lundbeck A/S
Recruiting - Conditions: Family; Alzheimer Dementia
Intervention: Behavioral: SCP Plus
Sponsors: The University of Texas at Arlington; National Institute on Aging (NIA)
Not yet recruiting - Condition: Dementia Alzheimers
Intervention: Other: Standard Diet
Sponsors: University of Aberdeen; NHS Grampian; Tenovus Scotland
Recruiting - Condition: Caregivers
Interventions: Behavioral: LEAF Positive Emotion Intervention; Other: Emotion Reporting Control Condition
Sponsors: Northwestern University; University of California, San Francisco
Not yet recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Healthy Volunteers
Intervention: Drug: [18F]MNI-1126
Sponsor: Invicro
Recruiting - Condition: Alzheimer Dementia
Interventions: Behavioral: Perspective Taking Reappraisal; Other: Basic Skill Building
Sponsor: The Hong Kong Polytechnic University
Not yet recruiting - Feasibility and Efficacy of Dietary Interventions for Older Adults With Subjective Cognitive DeclineConditions: Alzheimer Disease; Cognitive Impairment
Interventions: Dietary Supplement: MAD; Dietary Supplement: MIND
Sponsor: Johns Hopkins University
Not yet recruiting - Condition: Family Caregivers
Intervention: Behavioral: REACH-VIETNAM
Sponsor: University of California, Davis
Recruiting - Conditions: Healthy; Alzheimer Disease
Intervention: Other: [11C]-UCB-J
Sponsors: Rodin Therapeutics; QPS Netherlands B.V.; University Medical Center Groningen; VU University Medical Center
Recruiting - Conditions: Patients Aged 65-85 (Both Included); Diagnosed of Mild Cognitive Impairment; Diagnosed of Type 2 Diabetes in Active Treatment (Hypoglycemic Agents) for a Period ≥5 Years
Interventions: Device: Smart pillbox; Other: Interactive digital platform
Sponsors: Parc Sanitari Pere Virgili; Hospital Universitari Vall d'Hebron (HUVH - VHIR); Consorci Sanitari de Terrassa (CST); Fundació Recerca Mútua Terrassa (FMT); Clínica Universitària de la Fundació Universitària del Bages (FUB); Althaia Xarxa Assistencial Universitària de Manresa; Fundació Privada Hospital Asil de Granollers (HAG); Consorci Hospitalari de Vic (CHV); Lambdaloopers; Universitat Politècnica de Catalunya (UPC); Leitat; Mixestat; Meditecnologia; Mind the Byte
Not yet recruiting - Conditions: Stroke, Ischemic; Stroke Syndrome; Stroke; Stroke, Acute; Dementia; Brain Ischemia; Brain Diseases; Alzheimer Disease
Intervention: Behavioral: Neuro-QoL questionnaire
Sponsor: Chinese University of Hong Kong
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Bryostatin; Other: Placebo
Sponsors: Neurotrope Bioscience, Inc.; Worldwide Clinical Trials
Recruiting - Conditions: Alzheimer Disease; Dementia; Cognition Disorders
Intervention: Drug: SUVN-502
Sponsor: Suven Life Sciences Limited
Available - Conditions: Agitaton Associated With Alzheimer's Dementia; Alzheimer Dementia
Interventions: Drug: Brexpiprazole; Other: Placebo
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; H. Lundbeck A/S
Recruiting - Conditions: Functional Aging; Subjective Cognitive Concerns; Compensation Strategies; Brain Health Activities
Intervention: Behavioral: Intervention
Sponsor: University of California, Davis
Recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: Innovations in Dementia Empowerment and Action (IDEA); Behavioral: Reducing Disabilities in Alzheimer's Disease (RDAD)
Sponsor: University of Washington
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment; Mild Cognitive Impairment; Dementia Alzheimers; Dementia, Mild; Dementia, Alzheimer Type; Dementia of Alzheimer Type; Dementia; Cognitive Impairment, Mild; Cognitive Decline
Interventions: Device: GammaSense Stimulation System (Active Settings); Device: GammaSense Stimulation System (Sham Settings)
Sponsor: Cognito Therapeutics, Inc.
Recruiting - Conditions: Healthy Volunteers; Alzheimer Disease; Progressive Supranuclear Palsy
Intervention: Drug: [18F]MNI-958
Sponsor: Invicro
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: TRx0237
Sponsor: TauRx Therapeutics Ltd
Available - Condition: Alzheimer Disease
Intervention: Device: Flicker
Sponsors: Emory University; Georgia Institute of Technology
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: AMX0035; Drug: Placebo
Sponsors: Amylyx Pharmaceuticals Inc.; Alzheimer’s Drug Discovery Foundation; Alzheimer's Association
Recruiting - Condition: Insomnia Chronic
Interventions: Behavioral: CBT-I; Behavioral: MAP-I
Sponsor: University of California, Los Angeles
Recruiting - Condition: Alzheimer Disease
Interventions: Dietary Supplement: MMFS-205-SR; Dietary Supplement: Placebo
Sponsors: Neurocentria, Inc.; Ohio State University
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: UB-311; Drug: Placebo
Sponsor: United Neuroscience Ltd.
Recruiting - Conditions: Cerebral Amyloid Angiopathy; Intracranial Hemorrhages; Alzheimer Disease
Intervention: Drug: amyloid PET
Sponsor: National Taiwan University Hospital
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease; Alzheimer Dementia; Dementia, Vascular; Dementia With Lewy Bodies; Cognitive Impairment; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Cognitive Disorder
Interventions: Drug: N-831(Traneurocin) 10 mg QD; Drug: NA-831 (Traneurocin) 20 mg QD; Drug: NA-831 (Traneurocin) 40 mg QD; Drug: Placebo oral capsule QD
Sponsors: NeuroActiva, Inc.; The Florey Institute of Neuroscience and Mental Health
Not yet recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Age-Related Memory Disorders; Dementia
Interventions: Behavioral: Salient Cues; Behavioral: Spaced Retrieval Education
Sponsors: Grand Valley State University; Michigan State University
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: CT1812; Drug: Placebo
Sponsor: Cognition Therapeutics
Recruiting - Conditions: Alzheimer Disease; Mild to Moderate Alzheimer Disease
Intervention: Drug: GRF6019
Sponsor: Alkahest, Inc.
Recruiting - Condition: Alzheimer Disease (AD)
Interventions: Drug: LY3303560; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Conditions: Alzheimer Disease; Alzheimer Disease, Early Onset
Interventions: Dietary Supplement: MitoQ; Dietary Supplement: Placebo
Sponsor: University of Nebraska, Omaha
Not yet recruiting - Condition: Mild to Moderate Alzheimer's Disease
Interventions: Drug: CT1812; Drug: Placebo
Sponsor: Cognition Therapeutics
Recruiting - Conditions: Early Onset Alzheimer Disease; Alzheimer Disease; Mild Cognitive Impairment
Interventions: Drug: Flortaucipir; Drug: Florbetaben
Sponsors: Liana Apostolova; Alzheimer's Therapeutic Research Institute; National Institute on Aging (NIA); Alzheimer's Association
Recruiting - Conditions: Alzheimer Disease, Early Onset; Lewy Body Disease; Frontotemporal Lobar Degeneration
Intervention:
Sponsor: University Hospital, Lille
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: [C-11]PiB-PET/MRI
Sponsor: University of Alabama at Birmingham
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Interventions: Behavioral: Memory Training; Behavioral: Kundalini yoga and meditation
Sponsor: University of California, Los Angeles
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Dementia
Intervention: Device: Muscle relaxation using full body massage machine
Sponsor: Samsung Medical Center
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Crenezumab (RO5490245)
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Active Treatment- CT1812 100 mg; Drug: Placebo; Drug: Active Treatment- CT1812 300 mg
Sponsor: Cognition Therapeutics
Recruiting - Conditions: Healthy Volunteer; Alzheimer Disease; Frontotemporal Dementia; Parkinson Disease
Intervention: Drug: [18F]PI-2620
Sponsors: Asan Medical Center; Korea Health Industry Development Institute
Recruiting - Conditions: Alzheimer Disease; Intestinal Microbiota
Intervention: Procedure: Fecal sample collection
Sponsor: Nantes University Hospital
Not yet recruiting - Conditions: Mild Cognitive Impairment; Prodromal Alzheimer's Disease
Interventions: Drug: Placebo Oral Tablet; Drug: AGB101 220 mg tablet
Sponsors: AgeneBio; National Institute on Aging (NIA)
Not yet recruiting - Condition: Behavioral Symptoms
Interventions: Other: Approach based on the meanings of vocal behaviours; Other: Usual practices
Sponsor: Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Device: Active Neuro RX Gamma device; Device: Sham Neuro RX Gamma device
Sponsor: Vielight Inc.
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Other: biopsies of colon
Sponsor: Nantes University Hospital
Recruiting - Social Dancing Intervention for Older Adults at High Risk of Alzheimer's Disease and Other DementiasConditions: Alzheimer Disease; Dementia; Cognitive Decline; Cognitive Impairment; Dementia, Alzheimer Type
Interventions: Behavioral: Social Dancing; Behavioral: Treadmill Walking
Sponsors: Albert Einstein College of Medicine, Inc.; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Interventions: Other: low carbohydrate/high fat diet; Other: low fat/high carbohydrate diet
Sponsors: Wake Forest University Health Sciences; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Mild Cognitive Impairment; Dementia
Interventions: Diagnostic Test: Non-invasive, multimodal retinal imaging; Diagnostic Test: Cerebral imaging; Diagnostic Test: Neuropsychiatric testing; Diagnostic Test: Venous blood sampling
Sponsor: Universitaire Ziekenhuizen Leuven
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: 18F-AV-1451
Sponsor: Avid Radiopharmaceuticals
Recruiting - Conditions: Mild to Moderate Dementia Due to Alzheimer's Disease; With or Without Coexisting Cerebrovascular Disease
Interventions: Drug: RPh201; Other: Placebo
Sponsor: Regenera Pharma Ltd
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease
Interventions: Biological: ABvac40; Biological: Placebo
Sponsor: Araclon Biotech S.L.
Recruiting - Condition: APOE 4
Interventions: Drug: Levetiracetam 250 mg; Other: Placebo
Sponsors: Medical College of Wisconsin; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Intervention: Diagnostic Test: [18F]flutemetamol PET scan
Sponsors: University of Utah; National Institutes of Health (NIH)
Recruiting - Conditions: Sleep; Alzheimer Disease
Interventions: Behavioral: Behavioral sleep education; Behavioral: Education only
Sponsor: University of California, Los Angeles
Recruiting - Condition: Alzheimer Disease
Interventions: Other: Non-tailored intervention group; Other: Culturally tailored intervention group
Sponsors: University of Colorado, Denver; Washington State University; University of Arizona
Not yet recruiting - Conditions: Alzheimer Disease; Cholinesterase Inhibitors
Intervention: Drug: cholinesterase inhibitors (CI) (donepezil, galantamine or rivastigmine)
Sponsor: University Hospital, Bordeaux
Not yet recruiting - Conditions: Alzheimer Disease; Dementia Alzheimers; Dementia; Lewy Body Disease; Dementia, Lewy Body; Mild Cognitive Impairment
Intervention: Diagnostic Test: non-invasive retinal imaging
Sponsor: Universitaire Ziekenhuizen Leuven
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: TRx0237 8 mg/day; Drug: Placebo; Drug: TRx0237 16 mg/day
Sponsor: TauRx Therapeutics Ltd
Recruiting - Conditions: Alzheimer Disease; Suspected Alzheimer Disease
Interventions: Behavioral: Music lessons; Behavioral: Training intervention
Sponsors: University of Bergen; Uni Research; Bergen Municipality
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Gantenerumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Gantenerumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Mild Cognitive Impairment
Intervention: Other: Usual care setting
Sponsor: Eisai Korea Inc.
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Other: transdisciplinary approach; Other: multidisciplinary approach
Sponsors: University of Pittsburgh; Patient-Centered Outcomes Research Institute
Recruiting - Condition: Alzheimer's Disease or Related Disorder
Intervention: Behavioral: maintaining of occupational therapy
Sponsor: University Hospital, Bordeaux
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: VX-745; Drug: placebo
Sponsors: University Hospital, Toulouse; Fondation Plan Alzheimer
Not yet recruiting - Condition: Behavior Disorders
Intervention:
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment
Interventions: Behavioral: Routine care; Other: Coaching plus routine care
Sponsors: Hoag Memorial Hospital Presbyterian; Institute for Systems Biology
Recruiting - Conditions: Alzheimer Disease; Frontotemporal Dementia, Behavioral Variant
Intervention: Device: transcranial direct current stimulation (tDCS)
Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli
Recruiting - Condition: Alzheimer Disease
Intervention: Device: MHRC
Sponsors: Optina Diagnostics Inc.; McGill University; Polytechnique Montreal; Sunnybrook Health Sciences Centre
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: TEP
Sponsor: Immungenetics AG
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Transcranial Alternating Current Stimulation (tACS)
Sponsors: Beth Israel Deaconess Medical Center; Defense Advanced Research Projects Agency; Massachusetts General Hospital
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Vielight Neuro Gamma; Other: Sham Vielight Neuro Gamma
Sponsor: University of California, San Francisco
Recruiting - Condition: Memory Impairment
Interventions: Device: real anodal tDCS healthy elderly; Device: real tACS healthy elderly; Device: sham tES healthy elderly; Device: real anodal tDCS MCI; Device: real tACS MCI; Device: sham tES MCI; Device: real anodal tDCS AD; Device: real tACS AD; Device: sham tES AD
Sponsor: University of Bern
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: neflamapimod; Other: placebo
Sponsors: EIP Pharma, LLC; Worldwide Clinical Trials; VU University Medical Center
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Montelukast buccal film; Other: Placebo buccal film
Sponsor: IntelGenx Corp.
Recruiting - Conditions: Cerebral Small Vessel Diseases; Stroke, Lacunar
Interventions: Drug: Isosorbide Mononitrate XL (ISMN); Drug: Cilostazol; Drug: ISMN XL and Cilostazol; Other: Neither ISMN nor cilostazol
Sponsors: University of Edinburgh; British Heart Foundation; University of Nottingham
Recruiting - Conditions: Pain; Alzheimer Disease
Interventions: Behavioral: Auricular Point Acupressure; Behavioral: Education Control
Sponsor: Johns Hopkins University
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: Drug: Placebo; Drug: AVP-786
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Alzheimer Disease
Interventions: Device: GRASP DCE-MRI; Device: 3T Brain Scan
Sponsor: New York University School of Medicine
Not yet recruiting - Conditions: Traumatic Brain Injury; Alzheimer Disease; Veterans; Family Caregivers; Caregiver Burden; Quality of Life
Interventions: Other: ABC ANSWERS; Other: Control
Sponsors: Indiana University; Richard L. Roudebush VA Medical Center; Cleveland State University
Recruiting - Condition: Gait Disorders, Neurologic
Intervention:
Sponsor: University Hospital, Strasbourg, France
Recruiting - Conditions: Cognitive Impairment; Apolipoprotein E, Deficiency or Defect of; Critical Illness; Burns; Young Adult
Intervention: Diagnostic Test: APOE genotyping
Sponsor: Chelsea and Westminster NHS Foundation Trust
Not yet recruiting - Condition: Mild Cognitive Impairment
Intervention: Other: No intervention
Sponsor: Sun Yat-sen University
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment, Mild
Interventions: Behavioral: Smartphone Personal Assistant; Behavioral: Implementation Intention
Sponsors: Baylor University; National Institute on Aging (NIA)
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Group-based Cognitive Behavioral Therapy (CBT); Behavioral: Phone-based Cognitive Behavioral Therapy (CBT)
Sponsors: Emory University; Alzheimer's Association
Recruiting - Condition: Major Depressive Disorder
Interventions: Drug: F-18 AV-45; Drug: F-18-THK-5351
Sponsor: Chang Gung Memorial Hospital
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: JNJ-63733657; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Alzheimer Disease
Interventions: Diagnostic Test: CSF drawing during spinal anaesthesia; Diagnostic Test: Fasting blood sample; Diagnostic Test: Lumbar puncture
Sponsor: University Hospital, Lille
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: LY3002813; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Condition: Alzheimer's Disease
Interventions: Other: Multidimensional fragility index questionnaire RAI-Home Care; Other: Usual care
Sponsor: Assistance Publique Hopitaux De Marseille
Not yet recruiting - Conditions: Subjective Cognitive Decline; Preclinical Alzheimer's Disease
Intervention: Diagnostic Test: Neuropsychological scale
Sponsor: XuanwuH 2
Recruiting - Conditions: Lymphoma; Solid Malignancy; Alzheimer Disease; Myeloma
Interventions: Drug: PU-AD; Device: PET Scan; Other: Blood Draws
Sponsors: Samus Therapeutics, Inc.; Memorial Sloan Kettering Cancer Center; Weill Medical College of Cornell University; Rockefeller University
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: BIIB092; Drug: Placebo
Sponsor: Biogen
Recruiting - Condition: Alzheimer Disease
Intervention: Radiation: Low dose radiotherapy
Sponsor: Thomas Zilli
Recruiting - Condition: Alzheimer Disease
Interventions: Device: DBS of the fornix, power on; Device: DBS of the NbM, power on; Device: DBS of the fornix, power off; Device: DBS of the NbM, power off
Sponsors: Xuanwu Hospital, Beijing; Beijing Pins Medical Co., Ltd
Recruiting - Conditions: Cognitive Impairment; Alzheimer Disease
Interventions: Other: Relational care; Other: Hypno-analgesia
Sponsor: University Hospital, Montpellier
Not yet recruiting - Conditions: Brain Imaging; Mild Cognitive Impairment; Alzheimer Disease; Deep Brain Stimulation
Interventions: Device: Excitation; Device: Inhibition
Sponsor: University of California, Los Angeles
Recruiting - Conditions: Dementia, Vascular; Alzheimer Dementia; Lewy Body Dementia With Behavioral Disturbance
Interventions: Device: Activlink insole; Other: Activlink Phone Application
Sponsors: University of Florida; National Institute on Aging (NIA); Aster Labs, Inc
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Other: Exposure to familiar songs; Other: Music Experience Questionnaire; Other: Implicit tasks memory; Other: Questionnaires
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Duke University
Recruiting - Condition: Caregiver
Interventions: Behavioral: Intervention Condition; Behavioral: Control Condition
Sponsors: Weill Medical College of Cornell University; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Disease
Interventions: Other: Anodal tDCS; Other: Sham tDCS
Sponsors: University of Tromso; Helse Nord
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Neuro RX Gamma; Device: Sham
Sponsor: Vielight Inc.
Recruiting - Condition: Brain Injuries, Traumatic
Intervention: Procedure: Acupuncture
Sponsor: China Medical University Hospital
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: ACP Specialist Program
Sponsors: Indiana University; National Institute on Aging (NIA); Hebrew SeniorLife; Regenstrief Institute, Inc.
Not yet recruiting - Conditions: Living Alone; Alzheimer Disease; Mild Cognitive Impairment
Intervention:
Sponsor: University of California, San Francisco
Recruiting - Conditions: Alzheimer's Disease (Incl Subtypes); Dementia; Mild Cognitive Impairment
Interventions: Behavioral: Dance Group; Behavioral: Non-Group Dance; Behavioral: Social Group; Behavioral: No Contact
Sponsors: Wake Forest University Health Sciences; National Center for Complementary and Integrative Health (NCCIH)
Recruiting - Conditions: Elderly Patients; Cognitive Disorder; Alzheimer Disease
Intervention: Diagnostic Test: "Antillanisée" Mini Mental State Examination (MMSEa)
Sponsor: University Hospital Center of Martinique
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: AGN-242071; Drug: Placebo; Drug: Donepezil; Drug: Memantine
Sponsor: Allergan
Recruiting - Conditions: PSP - Progressive Supranuclear Palsy; PD - Parkinson's Disease; AD - Alzheimer's Disease; ALS (Amyotrophic Lateral Sclerosis)
Intervention: Diagnostic Test: Pupillometry
Sponsors: Massachusetts General Hospital; NeurOptics Inc.; University of Toronto
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Device: Transcutaneous vagal nerve stimulation; Device: Sham stimulation
Sponsors: University of Florida; Department of Health and Human Services; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease and Related Dementias
Interventions: Behavioral: SPIRIT-in person; Behavioral: SPIRIT-remote; Behavioral: Usual care
Sponsors: Emory University; National Institute on Aging (NIA)
Recruiting - Condition: Primary Progressive Aphasia
Intervention: Behavioral: Evidence-Based Treatment
Sponsors: Northwestern University; National Institute on Aging (NIA)
Recruiting - Condition: Hypertension
Interventions: Drug: Standard Care; Drug: Intensive Treatment
Sponsors: University of Texas Southwestern Medical Center; Texas Health Resources; Michigan State University
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Collaborative Dementia Care Program; Other: Screening Only
Sponsor: Indiana University
Not yet recruiting - Condition: Alzheimer Disease, Late Onset
Interventions: Diagnostic Test: CSF analysis; Radiation: Functional MRI
Sponsor: Ohio State University
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Dietary Supplement: Grape Powder; Dietary Supplement: Placebo Powder
Sponsors: University of California, Los Angeles; California Table Grape Commission
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: NDX-1017; Drug: Placebo
Sponsors: M3 Biotechnology, Inc.; Alzheimer’s Drug Discovery Foundation; Biotrial Inc.
Recruiting - Condition: Alzheimer Disease
Interventions: Other: Functionalities of the Lili Smart Solution activated; Other: Functionalities of the Lili Smart Solution non activated
Sponsors: Hospices Civils de Lyon; Lili smart
Recruiting - Conditions: Alzheimer Disease; Neurodegenerative Diseases
Intervention: Diagnostic Test: Cytology and Immunohistochemistry
Sponsor: University of Arkansas
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Transcranial Alternating Current Stimulation (tACS)
Sponsor: Beth Israel Deaconess Medical Center
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: RO7105705; Drug: Placebo; Drug: [18F]GTP1
Sponsor: Genentech, Inc.
Recruiting - Condition: Alzheimer Disease
Intervention: Device: tDCS
Sponsor: Benjamin CALVET
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Behavioral: ACT; Behavioral: Cycling Only; Behavioral: Cognitive Training Only; Behavioral: Stretching and Mental Stimulating Activities
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Rochester; Mayo Clinic; University of St Thomas
Recruiting - Conditions: Alzheimer Disease; Nurse Training
Intervention: Behavioral: RDAD Training
Sponsor: University of Washington
Recruiting - Conditions: Alzheimer Disease; Herpes Simplex 1; Herpes Simplex 2
Interventions: Drug: Valacyclovir; Drug: Placebo
Sponsors: New York State Psychiatric Institute; National Institutes of Health (NIH); National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Salsalate; Drug: Placebo
Sponsor: Adam Boxer
Recruiting - Conditions: Alzheimer Disease; Sleep Apnea
Intervention: Diagnostic Test: PET Scan and nocturnal polysomnography
Sponsor: New York University School of Medicine
Recruiting - Condition: Dementia
Interventions: Behavioral: Old SCHOOL Hip-Hop; Behavioral: My Pyramid in Egypt
Sponsor: Columbia University
Not yet recruiting - Condition: Cancer, Breast
Interventions: Behavioral: DECAD decision aid; Other: Home safety guide
Sponsor: Indiana University
Recruiting - Conditions: Alzheimer Disease; HIV
Intervention: Drug: F 18 T807
Sponsor: Washington University School of Medicine
Recruiting - Condition: Primary Progressive Aphasia With Suspected Alzheimer's Disease
Interventions: Drug: 18F-AV-1451; Device: PET
Sponsors: Northwestern University; National Institute on Aging (NIA)
Recruiting - Conditions: Glaucoma; Mild Cognitive Impairment; Glaucoma and Mild Cognitive Impairment; Healthy
Interventions: Device: Ocusweep test battery; Diagnostic Test: Neuropsychological test battery
Sponsors: Turku University Hospital; Ocuspecto Oy; European Commission
Recruiting - Conditions: Dementia; Parkinson; Altered Behavior in Alzheimer Disease; Demyelinating Autoimmune Diseases, CNS; Demyelinating Sensorimotor Neuropathy; Corticobasal Degeneration
Interventions: Procedure: Microcannula Harvest Adipose; Device: Centricyte 1000; Procedure: Sterile Normal Saline Infusion
Sponsors: Regeneris Medical; Global Alliance for Regenerative Medicine; Robert W. Alexander, MD, FICS; Regeneris Medical Inc
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Other: Adapted Tango Dance; Behavioral: Educational lectures
Sponsor: Emory University
Recruiting - Condition: Dementia-related Psychosis
Interventions: Drug: Placebo; Drug: Pimavanserin 34 mg; Drug: Pimavanserin 20 mg
Sponsor: ACADIA Pharmaceuticals Inc.
Recruiting - Conditions: Mild Dementia; Moderate Dementia
Intervention: Behavioral: iCST web-application
Sponsor: University of Nottingham
Recruiting - Condition: Alzheimer Disease; Prodromal
Interventions: Other: Regular health advice; Behavioral: Multidomain lifestyle; Dietary Supplement: Medical food
Sponsors: Karolinska Institutet; University of Eastern Finland; INSERM-University of Toulouse; Saarland University
Recruiting - Conditions: Dementia; Infection, Bacterial
Intervention: Behavioral: TRAIN-AD
Sponsor: Hebrew Rehabilitation Center, Boston
Recruiting - Conditions: Mild Cognitive Impairment; Prodromal Alzheimer's Disease; Mild Alzheimer's Disease
Interventions: Drug: Deferiprone 600mg delayed release tablets; Drug: Placebo Oral Tablet
Sponsor: Neuroscience Trials Australia
Recruiting - Conditions: Agitation in Patients With Dementia of the Alzheimer's Type; Alzheimer Disease; Agitation,Psychomotor
Interventions: Drug: AXS-05; Drug: Bupropion; Drug: Placebo
Sponsor: Axsome Therapeutics, Inc.
Recruiting - Conditions: Diet Modification; Cognitive Decline; Cognitive Change
Interventions: Other: Multicultural Healthy Diet; Other: Usual Diet plus Self-Care
Sponsors: Albert Einstein College of Medicine, Inc.; Penn State University; University of Pennsylvania; University of Minnesota - Clinical and Translational Science Institute; National Institute on Aging (NIA)
Recruiting - Conditions: Healthy; Mild Cognitive Impairment; Alzheimer Disease
Interventions: Device: real anodal transcranial direct current stimulation (tDCS); Device: sham transcranial direct current stimulation (tDCS)
Sponsor: University of Bern
Recruiting - Conditions: Alzheimer Disease; Aging; MCI
Intervention: Device: TMS
Sponsors: Duke University; National Institute on Aging (NIA); National Institutes of Health (NIH)
Not yet recruiting - Conditions: Alzheimer's Disease (Incl Subtypes); Cognitive Impairment
Intervention: Behavioral: Enhanced psycho-education about dementia and caregiving
Sponsors: University of California, Davis; National Institute on Aging (NIA); Alzheimer's Association
Recruiting - Condition: Alzheimer Disease
Interventions: Dietary Supplement: Challenge A - low calorie Ensure®; Dietary Supplement: Challenge B - Ensure® plus ketone esters (KE); Procedure: PET Scan; Behavioral: Cognitive Testing - FCSRT; Behavioral: Story Recall; Behavioral: BVRT; Behavioral: CogState One Card Learning
Sponsor: Wake Forest University Health Sciences
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Donepezil patch; Drug: aricept Tab
Sponsor: Icure Pharmaceutical Inc.
Recruiting - Conditions: Multiple Sclerosis; Parkinson Disease; Amyotrophic Lateral Sclerosis; Alzheimer Disease
Intervention: Procedure: lumbar puncture
Sponsors: Neuromed IRCCS; IRCCS Multimedica
Recruiting - Condition: Mild Alzheimer's Disease
Interventions: Drug: IONIS MAPTRx; Other: Placebo
Sponsor: Ionis Pharmaceuticals, Inc.
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: NP001; Drug: Placebo
Sponsors: Beau Nakamoto; Neuraltus Pharmaceuticals, Inc.
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: human umbilical cord blood derived mesenchymal stem cells; Other: Normal saline 2mL
Sponsor: Medipost Co Ltd.
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Lithium Carbonate; Drug: Placebo oral capsule
Sponsors: Ariel Gildengers; National Institute on Aging (NIA)
Recruiting - Condition: Osteoporosis
Intervention: Procedure: Hip bone sampling
Sponsor: Centre Hospitalier Universitaire de Nice
Recruiting - Conditions: Anticholinergics; Cognitive Function
Intervention:
Sponsors: Region Skane; Angelholm Hospital
Recruiting - Conditions: Alzheimer Disease, Early Onset; Alzheimer Disease; Alzheimer Disease, Late Onset; Dementia, Alzheimer Type; Logopenic Progressive Aphasia; Primary Progressive Aphasia; Visuospatial/Perceptual Abilities; Posterior Cortical Atrophy; Executive Dysfunction; Corticobasal Degeneration; Ideomotor Apraxia
Intervention:
Sponsors: University of California, Los Angeles; National Institute on Aging (NIA); University of Southern California
Recruiting - Conditions: Alzheimer Disease; Alzheimer Disease, Late Onset; Memory Loss; Patient Education as Topic
Intervention: Behavioral: Web-based education
Sponsor: Weill Medical College of Cornell University
Recruiting - Conditions: Dementia; Alzheimer Disease; Parkinson Disease; Lewy Body Disease; Parkinson-Dementia Syndrome; Frontotemporal Degeneration; Semantic Dementia; Progressive Nonfluent Aphasia; Progressive Supranuclear Palsy; Corticobasal Degeneration; Multiple System Atrophy; Mild Cognitive Impairment
Interventions: Diagnostic Test: Flutemetamol F18 Injection; Diagnostic Test: [18F]-RO6958948; Diagnostic Test: Elecsys (Roche) Abeta42, Ttau and Ptau; Diagnostic Test: Lumipulse (Fujirebio) Abeta42, Ttau and Ptau
Sponsors: Skane University Hospital; Lund University
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Prediabetic State
Intervention:
Sponsor: Wake Forest University Health Sciences
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: CNP520 50mg; Drug: CNP520 15mg; Other: Placebo to CNP520
Sponsors: Novartis Pharmaceuticals; Amgen; Banner Alzheimer's Institute
Recruiting - Conditions: Dementia; Alzheimer Disease; Memory Loss
Intervention: Behavioral: psychoeducational skills training intervention
Sponsor: Arizona State University
Recruiting - Condition: Mild Cognitive Impairment (MCI)
Intervention: Diagnostic Test: Diagnosis of MCI versus No MCI (SCI or healthy patient)
Sponsor: Assistance Publique Hopitaux De Marseille
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Active Transcranial Magnetic Stimulation; Device: Sham Transcranial Magnetic Stimulation
Sponsors: Universitat Oberta de Catalunya; Consorci Sanitari de Terrassa
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: AstroStem; Other: Placebo-Control
Sponsor: Nature Cell Co. Ltd.
Recruiting - Conditions: Sedentary Lifestyle; Stress, Psychological
Intervention: Behavioral: Exergame Experience
Sponsors: Brandeis University; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Crenezumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: [18F]THK-5351
Sponsor: Asan Foundation
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Guanfacine; Drug: Placebo
Sponsor: Imperial College London
Not yet recruiting - Condition: Dementia
Interventions: Drug: Escitalopram; Drug: Placebo
Sponsors: JHSPH Center for Clinical Trials; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: S-equol; Other: Placebo
Sponsors: Russell Swerdlow, MD; Ausio Pharmaceuticals, LLC
Recruiting - Condition: Dementia Alzheimers
Intervention: Behavioral: Psychosocial caregiver intervention
Sponsors: University of California, Davis; University of South Carolina
Recruiting - Conditions: Traumas, Brain; Alzheimer Disease; Dementia; Head Injury; Concussion, Brain; TBI
Interventions: Behavioral: Combined Aerobic and Resistance Exercise + Caregiver Skills Training; Behavioral: Stretching Balance and Flexibility + Caregiver Skills Training
Sponsors: Palo Alto Veterans Institute for Research; United States Department of Defense
Recruiting - Conditions: Delirium; Alzheimer Disease
Interventions: Behavioral: Physical Exercise Intervention; Behavioral: Cognitive Training Intervention; Behavioral: Stretching Control; Behavioral: Cognitive Control
Sponsor: Indiana University
Recruiting - Condition: PreDiabetes
Intervention: Behavioral: Diet and Exercise
Sponsor: University of Wisconsin, Madison
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: 11C-JNJ-63779586
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Gabapentin Enacarbil; Drug: Placebo Oral Tablet
Sponsors: University of Texas at Austin; National Institute on Aging (NIA)
Recruiting - Condition: Depression
Interventions: Behavioral: Guided Imagery and Mindfulness; Behavioral: Facilitated Discussion
Sponsors: Massachusetts General Hospital; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Disease; Dementia
Intervention: Other: HIGH and LOW meal ingestion
Sponsor: University of Washington
Recruiting - Conditions: Alzheimer Disease; Healthy Volunteers
Interventions: Drug: [18F] MNI-946; Drug: [18F]Florbetapir
Sponsor: Invicro
Recruiting - Condition: Mild to Moderate Alzheimer's Disease
Interventions: Drug: 400mg LM11A-31-BHS; Drug: 800mg LM11A-31-BHS; Drug: Placebos
Sponsors: PharmatrophiX Inc.; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment
Interventions: Drug: Nicotinamide; Drug: Placebo Comparator
Sponsor: University of California, Irvine
Recruiting - Conditions: Delirium; Cognitive Impairment; Alzheimer; Early Onset; Trauma; Polytrauma; Traumatic Brain Injury; ICU; Critical Illness
Intervention: Other: Non-interventional observational prospective cohort study
Sponsors: Vanderbilt University Medical Center; National Institutes of Health (NIH); National Institute of General Medical Sciences (NIGMS)
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: N-hydroxy-N'-phenyl-octanediamide (Vorinostat)
Sponsors: German Center for Neurodegenerative Diseases (DZNE); University Hospital, Bonn; University of Göttingen
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: BIIB076; Drug: Placebo
Sponsor: Biogen
Recruiting - Conditions: Alzheimer Disease; Healthy Volunteers; Progressive Supranuclear Palsy
Interventions: Drug: [18F]MNI-958; Drug: [18F]Florbetapir; Drug: DaTscan
Sponsor: Molecular NeuroImaging
Recruiting - Conditions: Elderly; Alzheimer Disease
Interventions: Procedure: Actigraphy; Procedure: Nocturnal Polysomnograpahy (NPSG)
Sponsor: New York University School of Medicine
Recruiting - Condition: Alzheimer Disease
Interventions: Other: tablet therapy; Other: usual care
Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Behavioral: Family-centered Function-focused Care (Fam-FFC)
Sponsors: Penn State University; National Institutes of Health (NIH)
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Elenbecestat (E2609); Drug: Placebo
Sponsors: Eisai Co., Ltd.; Biogen
Recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: Aerobic exercise; Behavioral: Stretch and Strength
Sponsors: University of Calgary; Canadian Institutes of Health Research (CIHR)
Recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: Tele-Savvy; Behavioral: Healthy Living Education Program
Sponsors: Emory University; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Frontal Dementia; Huntington Disease; Traumatic Brain Injury; Stroke
Intervention: Behavioral: social cognition
Sponsor: Centre Hospitalier Universitaire, Amiens
Recruiting - Condition: Dementia
Interventions: Drug: Carbamazepine; Drug: Mirtazapine; Other: Placebo
Sponsors: University of Sussex; Norwich Clinical Trials Unit; University of East Anglia; University of Cambridge; University College, London; London School of Economics and Political Science; University of Manchester; University of Newcastle Upon-Tyne; Birmingham and Solihull Mental Health NHS Foundation Trust; Alzheimer's Society; The Centre for Dementia Studies, Brighton and Sussex Medical School and SPFT
Recruiting - Condition: Subjective Cognitive Decline
Intervention: Drug: 18F-Florbetaben (FBB)
Sponsor: Fundacion Clinic per a la Recerca Biomédica
Not yet recruiting - Conditions: Psychosis; Dementia; Aggression; Agitation; Alzheimer Dementia
Interventions: Drug: MP-101; Drug: Placebo
Sponsor: Mediti Pharma Inc.
Recruiting - Conditions: Alzheimer Disease (AD); Frontotemporal Lobar Degeneration; Dementia With Lewy Bodies (DLB); Parkinson Disease Dementia (PDD); Progressive Supranuclear Palsy (PSP); Corticobasal Degeneration (CBD)
Intervention:
Sponsors: Amoneta Diagnostics SAS; European Commission; Firalis SA; University Hospital, Strasbourg; Centre Hospitalier Universitaire Vaudois; IRCCS Centro San Giovanni di Dio Fatebenefratelli; Hôpitaux Civils de Colmar; Istanbul University; Assistance Publique - Hôpitaux de Paris; University Hospital, Lille; University Hospital, Geneva; Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Erasme University Hospital; University Hospital, Montpellier; Centre Hospitalier Universitaire de Besancon; Centre Hospitalier Universitaire de Nice
Recruiting - Conditions: Alzheimer's Disease; Lewy Body Dementia; Parkinson's Disease
Interventions: Radiation: DaTscan; Radiation: F18-AV-45; Radiation: FDG-PET; Genetic: APOE genotype; Procedure: Polysomnogram; Behavioral: Clinical Assessment
Sponsors: Douglas Scharre; Avid Radiopharmaceuticals; Mangurian Foundation
Not yet recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Herpes Simplex
Intervention: Drug: Valaciclovir 500Mg Tablet
Sponsor: Hugo Lovheim
Recruiting - Conditions: Alzheimer Dementia; Dementia, Vascular; Dementia, Lewy Body; Dementia Parkinson's Disease
Intervention: Behavioral: Resource oriented music therapy
Sponsors: University of Bergen; NKS Olaviken Alderspsykiatriske sykehus
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Rivastigmine
Sponsor: Novartis Pharmaceuticals
Not yet recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Lanabecestat
Sponsors: Eli Lilly and Company; AstraZeneca
Recruiting - Condition: Preclinical Alzheimer's Disease
Intervention: Behavioral: Exergame
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - Conditions: Alzheimer's Disease; Parkinson's Disease; Frontotemporal Lobar Degeneration
Intervention: Behavioral: Observational Study
Sponsor: University Health Network, Toronto
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Elenbecestat (E2609); Drug: Placebo
Sponsors: Eisai Co., Ltd.; Biogen
Recruiting - Conditions: Alzheimer Disease; Amyloid Beta-Peptides; Risk Assessment; Education; Neuropsychological Tests; Neuroimaging
Interventions: Behavioral: Alzheimer's Disease Risk Disclosure; Behavioral: Amyloid Brain Imaging and Alzheimer's Disease Risk Disclosure
Sponsors: Brigham and Women's Hospital; University of Pennsylvania; University of Michigan; Duke University; Boston University; National Institute on Aging (NIA)
Recruiting - Condition: Mild Cognitive Impairment
Intervention: Device: No intervention is part of this study but patients use an EEG device during observational data collection.
Sponsor: VA Boston Healthcare System
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Placebo Capsule(s) Once a Day by Mouth; Drug: Nilotinib Capsule(s) Once a Day by Mouth
Sponsor: Georgetown University
Recruiting - Conditions: Encephalopathy; HIV-encephalopathy; Alzheimer Dementia
Intervention: Device: Nasal Brushing
Sponsor: University of Turin, Italy
Recruiting - Conditions: Mild Cognitive Impairment; Major Depressive Disorder; Alzheimer's Dementia; Transcranial Direct Current Stimulation; tDCS
Interventions: Other: Receive tDCS+CR; Other: Facilitate tDCS + CR
Sponsors: Centre for Addiction and Mental Health; CAMH Foundation
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Posiphen; Drug: Placebo
Sponsors: QR Pharma Inc.; Alzheimer's Disease Cooperative Study (ADCS)
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Interventions: Device: Sapphire II; Drug: Aftobetin-HCl; Radiation: Positron Emission Tomography
Sponsor: Cognoptix, Inc.
Recruiting - Condition: Alzheimer's Disease
Interventions: Device: rTMS active treatment; Device: rTMS sham treatment
Sponsors: University of Manitoba; Weston Brain Institute
Recruiting - Conditions: Cognitively Normal Older Adults; Hypertension; Subjective Cognitive Decline; Family History of Alzheimer's Disease
Interventions: Drug: Angiotensin II receptor blocker (ARB, losartan) and calcium channel blocker (CCB, amlodipine); Behavioral: Aerobic Exercise Training; Other: Usual Care; Behavioral: Stretching Exercise; Drug: Atorvastatin
Sponsors: University of Texas Southwestern Medical Center; Texas Health Resources; University of Kansas Medical Center; Washington University School of Medicine; Pennington Biomedical Research Center; Michigan State University
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: The Residential Care Transition Module
Sponsors: University of Minnesota - Clinical and Translational Science Institute; Johns Hopkins University; New York University School of Medicine; Benjamin Rose Institute; Emory University
Recruiting - Conditions: Alzheimer Disease; ELECTROENCEPHALOGRAPHIC VARIANT PATTERN 1 (Disorder)
Intervention: Other: Rapid Visual Information Processing (RVIP) test
Sponsor: University Hospital, Lille
Recruiting - Condition: Alzheimer's Disease or Vascular Dementia
Interventions: Drug: BAC; Drug: Matched placebo
Sponsor: Charsire Biotechnology Corp.
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: ABBV-8E12; Drug: placebo for ABBV-8E12
Sponsor: AbbVie
Recruiting - Conditions: Early Onset Alzheimer Disease; Mild Cognitive Impairment; Depression; Aging
Intervention:
Sponsor: ElMindA Ltd
Recruiting - Condition: Epilepsy
Intervention: Biological: profile of CSF biomarkers of AD
Sponsor: Hospices Civils de Lyon
Recruiting - Conditions: Mild Cognitive Impairment (MCI); Alzheimer's Disease (AD)
Intervention:
Sponsors: University of Southern California; Northern California Institute of Research and Education; National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute
Recruiting - Conditions: Alzheimer's Disease; Dementia
Interventions: Other: Placebo; Other: Medication Therapy Management (MTM); Drug: Scopolamine patch
Sponsors: Daniela Moga; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease
Intervention: Behavioral: Cognitive tests
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Conditions: Alteration of Cognitive Function; Hypoxia
Intervention: Other: 2-hour period of hypoxia
Sponsor: University Hospital, Lille
Recruiting - Cognitive-motor Intervention Using Virtual Reality for Middle-aged Individuals at High Dementia RiskCondition: Alzheimer's Disease (AD)
Interventions: Behavioral: cognitive training by virtual reality; Behavioral: watching a scientific TV documentary; Device: treadmill
Sponsor: Sheba Medical Center
Recruiting - Condition: Agitation in Dementia, Including Alzheimer's Disease
Interventions: Drug: ITI-007; Drug: Placebo
Sponsor: Intra-Cellular Therapies, Inc.
Recruiting - Condition: Alzheimer's Dementia
Intervention:
Sponsors: University of Edinburgh; Innovative Medicines Initiative
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Dronabinol (Marinol®); Drug: Placebo
Sponsors: Johns Hopkins University; Mclean Hospital
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: BI 425809 dose 1; Drug: BI 425809 dose 2; Drug: BI 425809 dose 3; Drug: BI 425809 dose 4; Drug: Placebo
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Lanabecestat; Drug: Placebo
Sponsors: Eli Lilly and Company; AstraZeneca
Recruiting - Condition: Alzheimer's Disease
Interventions: Radiation: 10 GY in 5 daily fractions; Radiation: 20 GY in 10 daily fractions
Sponsor: Virginia Commonwealth University
Recruiting - Conditions: Mild Cognitive Impairment; Dementia; Alzheimer's Disease
Intervention: Drug: [18F]Flutemetamol
Sponsor: University of Utah
Recruiting - Condition: Alzheimer's Disease
Intervention: Device: Actigraph
Sponsor: New York University School of Medicine
Not yet recruiting - Conditions: Atypical Alzheimer's Disease; Logopenic Progressive Aphasia (LPA); Posterior Cortical Atrophy (PCA)
Interventions: Drug: F-18 AV 1451; Drug: C-11 PiB
Sponsor: Mayo Clinic
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: icosapent ethyl (IPE); Other: gel cap placebo
Sponsors: VA Office of Research and Development; University of Wisconsin, Madison
Recruiting - Condition: Dementia
Interventions: Drug: Xanamem™; Drug: Placebo (for Xanamem™)
Sponsors: Actinogen Medical; ICON Clinical Research
Recruiting - Condition: Dementia
Intervention: Device: Home monitoring kit
Sponsor: Lund University
Recruiting - Conditions: Aging; Cognitive Ability, General
Interventions: Behavioral: Moderate-aerobic walking; Radiation: Positron Emission Tomography (PET) scan; Behavioral: Healthy living education; Device: Physical activity monitor
Sponsor: University of Southern California
Recruiting - Condition: Alzheimer's Disease
Intervention: Procedure: 18F-Flutemetamol & 18F-FDG
Sponsors: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Hospital Clinic of Barcelona; General Electric
Recruiting - Conditions: Dementia; Alzheimer's Disease
Interventions: Behavioral: UCF Caregiver Support Group; Behavioral: Community Support Groups
Sponsors: University of Central Florida; Alzheimer's and Dementia Resource Center
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Nicotine Transdermal Patch; Drug: Placebo Patch
Sponsors: University of Southern California; National Institute on Aging (NIA); Vanderbilt University; Alzheimer's Therapeutic Research Institute
Recruiting - Conditions: Amyloid Cerebral Angiopathy; Alzheimer Disease
Interventions: Device: Pet scan with FBB; Device: MRI scan; Biological: APO E genotyping
Sponsor: Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease; Healthy
Interventions: Device: DVA; Device: FDOCT; Device: Pattern ERG; Device: Optical Coherence Tomography
Sponsor: Medical University of Vienna
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Neurodegenerative Diseases
Intervention: Drug: [18F]THK-5351
Sponsors: Jae Seung Kim; Korea Health Industry Development Institute; Samsung Medical Center
Recruiting - Conditions: Multiple Sclerosis; Alzheimer's Disease
Intervention: Drug: [F-18]PBR06
Sponsor: Brigham and Women's Hospital
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Placebo; Drug: Candesartan
Sponsor: Emory University
Recruiting - Condition: Alzheimer Disease
Interventions: Other: Traditional Proton fMRI; Other: Hyperpolarized Xenon-129 fMRI; Drug: Hyperpolarized Xenon-129; Device: 1H-129Xe Dual-Tuned Quadrature Head Coil
Sponsors: Thunder Bay Regional Research Institute; Lakehead University; Thunder Bay Regional Health Sciences Centre
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Piromelatine; Drug: Placebo
Sponsor: Neurim Pharmaceuticals Ltd.
Recruiting - Conditions: Alzheimer Disease; Down Syndrome; Mild Cognitive Impairment
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: Longeveron Mesenchymal Stem Cells; Biological: Placebo
Sponsor: Longeveron LLC
Recruiting - Conditions: Alzheimer Disease; Dementia; Heart Failure; Pulmonary Disease, Chronic Obstructive
Intervention: Behavioral: ACP Video Program
Sponsors: Brown University; National Institute on Aging (NIA); Hebrew SeniorLife; Massachusetts General Hospital; Genesis HealthCare; PruittHealth
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: SUVN-502; Drug: Placebo
Sponsor: Suven Life Sciences Limited
Recruiting - Condition: Mild Cognitive Impairment
Intervention:
Sponsors: New York University School of Medicine; NeuroTrack Technologies, Inc.
Recruiting - Association Between Cerebral Arterial Vascular Flow and Sleep Apnea in Neurodegenerative AlterationsCondition: Alzheimer Disease
Intervention: Other: Vascular flow measurement by PC-MRI
Sponsor: Central Hospital Saint Quentin
Recruiting - Conditions: Alzheimer's Disease; Dementia; Dementia, Vascular; Caregivers; Veterans
Interventions: Behavioral: Counseling (C); Behavioral: Care Consultation (CC)
Sponsor: VA Office of Research and Development
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: CAD106 Immunotherapy; Other: Placebo to CAD106; Drug: CNP520; Other: Placebo to CNP520
Sponsors: Novartis Pharmaceuticals; Banner Alzheimer's Institute; National Institute on Aging (NIA); Alzheimer's Association; Amgen
Recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Banner Health
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: ALZT-OP1a; Drug: ALZT-OP1b; Other: Placebo ALZT-OP1a; Other: Placebo ALZT-OP1b
Sponsors: AZTherapies, Inc.; PharmaConsulting Group; KCAS Bio; APCER Life Sciences
Recruiting - Condition: Alzheimer's Disease
Interventions: Procedure: Repetitive Transcranial Magnetic Stimulation; Procedure: Repetitive Transcranial Magnetic Stimulation - Sham
Sponsors: Centre for Addiction and Mental Health; Brain & Behavior Research Foundation; University of Toronto
Recruiting - Condition: Alzheimer's Disease
Interventions: Device: Erchonia ALS Laser; Device: Placebo Laser
Sponsor: Erchonia Corporation
Not yet recruiting - Conditions: Memory Disorders; Mild Cognitive Impairment; Alzheimer's Disease
Interventions: Behavioral: Intervention Group; Behavioral: Control Group
Sponsors: Boston University; Wallace H. Coulter Foundation
Recruiting - Conditions: Mild Cognitive Impairment; Probable Alzheimer's Disease
Interventions: Other: Modified Atkins Diet; Other: NIA Diet for Seniors
Sponsor: Johns Hopkins University
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Vascular Cognitive Impairment; Parkinson's Disease; Lewy Body Disease
Intervention: Other: Flutemetamol PET scan
Sponsors: Sunnybrook Health Sciences Centre; Brain Canada; Weston Brain Institute; GE Healthcare; University Health Network, Toronto; Centre for Addiction and Mental Health; Baycrest; St. Michael's Hospital, Toronto; Kensington Eye Institute
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention: Drug: grape seed polyphenolic extract, resveratrol
Sponsors: Johns Hopkins University; Icahn School of Medicine at Mount Sinai
Recruiting - Condition: Alzheimer's Disease
Intervention:
Sponsors: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Obra Social La Caixa, Spain
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Telmisartan 20mg; Drug: Telmisartan 40mg; Drug: Placebo
Sponsor: Emory University
Recruiting - Conditions: Alzheimer's Disease; Vascular Dementia
Interventions: Drug: BAC; Other: BAC Matched Vehicle
Sponsors: Charsire Biotechnology Corp.; A2 Healthcare Taiwan Corporation
Not yet recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment
Interventions: Drug: Insulin aspart; Drug: Placebo
Sponsors: Wake Forest University Health Sciences; National Institute on Aging (NIA); General Electric
Recruiting - Conditions: Alzheimer's Disease; Obesity; Diabetes Mellitus
Interventions: Dietary Supplement: Boost A; Behavioral: Healthy Living Diet
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Intervention: Drug: AVP-786
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: Drug: AVP-786; Drug: Placebo
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: Drug: AVP-786; Drug: Placebo
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Alzheimer's Disease
Intervention: Device: Thymatron IV device (Somatics)
Sponsor: Central Institute of Mental Health, Mannheim
Not yet recruiting - Conditions: Major Depression; Alzheimer's Disease; Alcoholism; Schizophrenia
Intervention:
Sponsor: Charite University, Berlin, Germany
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Biological: Elderberry Juice; Other: Placebo
Sponsor: University of Missouri-Columbia
Recruiting - Conditions: Mild Cognitive Impairment; Major Depressive Disorder, Recurrent, In Remission; Major Depressive Disorder, Single Episode, in Full Remission
Interventions: Other: tDCS + CR; Other: sham tDCS + sham CR
Sponsors: Centre for Addiction and Mental Health; Brain Canada; Applied Health Research Centre; Queen's University; Baycrest Centre for Geriatric Care; St. Michael's Hospital, Toronto; Sunnybrook Health Sciences Centre; University Health Network, Toronto
Recruiting - Condition: Alzheimer Disease
Intervention: Radiation: Florbetaben
Sponsor: Judit Pich Martínez
Recruiting - Condition: Alzheimer's Disease
Intervention: Other: 7 Tesla MRI with memory task and non-invasive neurostimulation
Sponsors: Maastricht University Medical Center; Netherlands Organisation for Scientific Research
Recruiting - Condition: Alzheimer's Disease
Interventions: Radiation: 5 daily fractions of 2 Gy; Radiation: 10 daily fractions of 2 Gy
Sponsor: William Beaumont Hospitals
Not yet recruiting - Conditions: Healthy; Neurodegenerative Disease
Intervention:
Sponsor: University of California, San Francisco
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease; Dementia
Intervention: Drug: Flutemetamol (Vizamyl)
Sponsor: University of Zurich
Recruiting - Conditions: Alzheimer's Disease; Dementia
Interventions: Other: Online counseling via Zoom teleconferencing; Other: Telephone support as needed
Sponsor: New York University School of Medicine
Recruiting - Conditions: Apathy; Alzheimer's Disease
Interventions: Drug: Methylphenidate; Drug: Placebo
Sponsors: Johns Hopkins Bloomberg School of Public Health; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Small Vessel Disease White Matter Hyperintensities Subtype; Vascular Cognitive Impairment
Intervention:
Sponsor: Dr. Sandra E Black
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Benfotiamine
Sponsors: Burke Medical Research Institute; Burke Rehabilitation Hospital; Columbia University; National Institute on Aging (NIA); Alzheimer’s Drug Discovery Foundation; Montefiore-Albert Einstein College of Medicine
Recruiting - Conditions: Alzheimer Disease; Battery
Interventions: Drug: Memantine; Drug: Placebo
Sponsor: University Hospital, Lille
Recruiting - Conditions: Alzheimer's Disease; Traumatic Brain Injury; Depression
Intervention: Drug: 18F-AV-1451
Sponsor: Avid Radiopharmaceuticals
Recruiting - Conditions: Alzheimer's Disease (AD); Alzheimer's Disease (AD) Related Disorders
Intervention: Other: in Memento-VASCOD
Sponsors: University Hospital, Bordeaux; Ministry for Health and Solidarity, France
Recruiting - Condition: Dementia
Interventions: Drug: Cholinesterase inhibitor; Drug: Sham discontinuation
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention: Device: Transcranial direct current stimulation (tDCS) Soterix Medical Inc. tDCS unit
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Alzheimer's Disease; Psychosis; Agitation
Interventions: Drug: Lithium; Drug: Placebo
Sponsors: New York State Psychiatric Institute; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Plaque, Amyloid
Intervention:
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Genetic Risk for Alzheimer's Disease
Interventions: Drug: donepezil HCL; Drug: Placebo
Sponsors: The Cleveland Clinic; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Hypertension
Interventions: Drug: Perindopril; Drug: Telmisartan
Sponsors: Sunnybrook Health Sciences Centre; Alzheimer’s Drug Discovery Foundation; Weston Brain Institute
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: human umbilical cord blood derived mesenchymal stem cells; Other: Normal saline 2mL
Sponsor: Medipost Co Ltd.
Recruiting - Conditions: Alzheimer's Disease; Dementia
Intervention:
Sponsor: Banner Health
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: levetiracetam
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting - Condition: Alzheimer's Disease
Interventions: Other: Aerobic Exercise; Other: Standard of Care
Sponsors: University of Kansas Medical Center; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimers Disease; Postoperative Delirium; Post Operative Cognitive Dysfunction
Interventions: Drug: Total intravenous anesthesia with propofol; Drug: General anesthesia with isoflurane
Sponsor: Duke University
Recruiting - Conditions: Ataxia; Dystonia; Parkinson's Disease; Amyotrophic Lateral Sclerosis; Corticobasal Degeneration; Multiple System Atrophy; Alzheimer's Disease; Lewy Body Dementia; Parkinson Disease-Dementia; Dentatorubral-pallidoluysian Atrophy; Creutzfeldt-Jakob Disease and Fatal Familial Insomnia; Fragile X-associated Tremor/Ataxia Syndrome; Krabbe's Disease; Niemann-Pick Disease, Type C; Neuronal Ceroid Lipofuscinosis
Intervention:
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Disease
Intervention: Other: Personalized Exercise Regimen
Sponsor: University Health Network, Toronto
Recruiting - Condition: All Diagnosed Health Conditions
Intervention:
Sponsor: Sanguine Biosciences
Recruiting - Conditions: Alzheimer's Disease; Dementia
Interventions: Drug: Spinal anesthesia group: bupivacaine 10-15mg; Drug: General anesthesia group: induction propofol 1.5-2mg/kg and fentanyl 1-3g/kg, maintained with isoflurane or sevoflurane; Genetic: Blood test; Other: Lumbar spinal tap; Behavioral: Montreal Cognitive Assessment (MOCA) and MMSE
Sponsor: University Health Network, Toronto
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Curcumin; Behavioral: aerobic yoga; Behavioral: non aerobic yoga; Dietary Supplement: Placebo
Sponsors: VA Office of Research and Development; heather.d'adamo@va.gov
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: BNC
Sponsor: National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Oxidative Stress; Adrenocortical Hyperfunction
Intervention:
Sponsor: Raffaele Antonelli Incalzi
Recruiting - Conditions: Traumatic Brain Injury; Post Traumatic Stress Disorder; Alzheimer's Disease; Mild Cognitive Impairment
Intervention:
Sponsors: University of Southern California; United States Department of Defense; Telemedicine & Advanced Technology Research Center; Northern California Institute of Research and Education; San Francisco Veterans Affairs Medical Center; Alzheimer's Therapeutic Research Institute
Recruiting - Condition: Postoperative Cognitive Dysfunction
Interventions: Drug: Florbetapir F 18 (18F-AV-45); Other: no intervention
Sponsors: University of California, San Francisco; Alzheimer’s Drug Discovery Foundation; Avid Radiopharmaceuticals
Recruiting - Conditions: Alzheimer Disease and Related Dementias; Inherited Metabolic Disorders (Inborn Errors of Metabolism); Undiagnosed Diseases; Healthy Volunteer
Intervention:
Sponsor: National Human Genome Research Institute (NHGRI)
Recruiting - Conditions: Alzheimer's Disease; Cardiovascular Risk Factors
Interventions: Other: optimal care of VRF; Other: standard care
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Conditions: Ischemic Stroke; Hemorrhagic Stroke
Intervention:
Sponsor: Ludwig-Maximilians - University of Munich
Recruiting - Conditions: Cerebrovascular Disorders; Dementia
Intervention:
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Condition: Neurodegenerative Disorders
Intervention:
Sponsor: Hadassah Medical Organization
Recruiting - Conditions: Alzheimer Disease; Late Onset Alzheimer Disease; Dementia
Intervention:
Sponsors: Indiana University; National Institute on Aging (NIA)
Recruiting
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