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- Condition: Alzheimer Disease
Interventions: Drug: Montelukast; Drug: Placebo oral tablet
Sponsor: Emory University
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Transcranial Alternating Current Stimulation (tACS); Other: Sham Transcranial Alternating Current Stimulation
Sponsors: Beth Israel Deaconess Medical Center; Massachusetts General Hospital; National Institutes of Health (NIH); National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Intervention:
Sponsors: Shanghai 10th People's Hospital; Massachusetts General Hospital
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: CT1812; Drug: Placebo
Sponsor: Cognition Therapeutics
Recruiting - Condition: Alzheimer Disease
Interventions: Device: DBS-f On; Device: DBS Off
Sponsor: Functional Neuromodulation Ltd
Recruiting - Condition: Alzheimer's
Interventions: Drug: Ginkgo biloba dispersible tablets; Drug: Donepezil; Drug: Ginkgo biloba dispersible tablets and Donepezil
Sponsor: The First Affiliated Hospital with Nanjing Medical University
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Transcranial Ultrasound Stimulation
Sponsors: National Yang Ming University; Taipei Veterans General Hospital, Taiwan
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Dietary Supplement: brain polypeptide solution; Other: same package of placebo
Sponsors: Peking Union Medical College Hospital; Zhitong Biopharma CO.,LTD
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Biological: 100 million cells allogeneic hMSC; Biological: 200 million cells allogeneic hMSC
Sponsor: Bernard (Barry) Baumel
Recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Duke University
Recruiting - Condition: Alzheimer Disease
Intervention: Diagnostic Test: ADASCog
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: CB-AC-02; Biological: Placebo
Sponsor: CHABiotech CO., Ltd
Recruiting - Condition: Moderate Alzheimer's Disease
Interventions: Drug: GV1001; Drug: Normal saline
Sponsor: GemVax & Kael
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Biological: CAD106 Immunotherapy; Other: Placebo to CAD106; Drug: CNP520; Other: Placebo to CNP520
Sponsors: Novartis Pharmaceuticals; Banner Alzheimer's Institute; National Institute on Aging (NIA); Alzheimer's Association; Amgen
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Riluzole; Drug: Placebo
Sponsors: Icahn School of Medicine at Mount Sinai; Rockefeller University
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: Dasatinib + Quercetin
Sponsors: The University of Texas Health Science Center at San Antonio; Mayo Clinic
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Other: non ontervention / observational study
Sponsor: Centre Hospitalier Universitaire de Nice
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: 18F-MK-6240; Drug: 18F-Florbetaben
Sponsors: Adam Brickman; National Institute on Aging (NIA)
Recruiting - Condition: Mild to Moderate Alzheimer's Disease
Interventions: Drug: AR1001; Drug: Placebo
Sponsor: AriBio Co., Ltd.
Recruiting - Condition: Mild to Moderate Alzheimer's Disease
Interventions: Drug: CT1812; Drug: Placebo
Sponsor: Cognition Therapeutics
Recruiting - Condition: Alzheimer Disease
Interventions: Device: GENUS device (Active Settings); Device: GENUS device (Sham Settings)
Sponsor: Massachusetts Institute of Technology
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Blood Brain Barrier (BBB) Disruption
Sponsors: InSightec; Focused Ultrasound Foundation
Recruiting - Condition: Mild to Moderate Alzheimer's Disease
Interventions: Drug: ORY-2001 Low dose; Drug: ORY-2001 High dose; Drug: Placebo
Sponsors: Oryzon Genomics S.A.; Alzheimer’s Drug Discovery Foundation
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Blood Brain Barrier (BBB) Disruption
Sponsor: InSightec
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Rivastigmine
Sponsor: Novartis Pharmaceuticals
Recruiting - Condition: Alzheimer Disease
Intervention: Behavioral: Neurofeedback
Sponsors: Oregon Health and Science University; National Institutes of Health (NIH); National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - Condition: Alzheimer's Disease
Interventions: Other: Adapted Tango Dance; Behavioral: Educational lectures
Sponsor: Emory University
Recruiting - Condition: Alzheimer's Disease
Intervention: Other: Personalized Exercise Regimen
Sponsor: University Health Network, Toronto
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia
Interventions: Device: GENUS device (Active Settings); Device: GENUS device (Sham Settings)
Sponsor: Massachusetts Institute of Technology
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Ketogenic Diet; Behavioral: Therapeutic Lifestyles Changes Diet
Sponsors: University of Kansas Medical Center; National Institute on Aging (NIA)
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Dapagliflozin; Other: Placebo
Sponsor: Jeff Burns, MD
Recruiting - Condition: Alzheimer Disease
Intervention: Diagnostic Test: [F-18]AV-1451-PET
Sponsor: University of Alabama at Birmingham
Not yet recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Chinese University of Hong Kong
Recruiting - Condition: Alzheimer Disease
Intervention: Diagnostic Test: Lumbar punction
Sponsor: University of Chile
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: [C-11]PiB-PET/MRI
Sponsor: University of Alabama at Birmingham
Recruiting - Condition: Alzheimer Disease
Intervention: Behavioral: Facial expression recognition task
Sponsor: University Hospital, Grenoble
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Posiphen; Drug: Placebo
Sponsors: QR Pharma Inc.; Alzheimer's Disease Cooperative Study (ADCS)
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Collaborative Dementia Care Program; Other: Screening Only
Sponsor: Indiana University
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: S-equol; Other: Placebo
Sponsors: Russell Swerdlow, MD; Ausio Pharmaceuticals, LLC
Recruiting - Condition: Alzheimer Disease
Intervention: Biological: Fecal Microbiota Transplant
Sponsors: University of Wisconsin, Madison; Wisconsin Partnership Program
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: DAOI-A group; Drug: DAOI-B group; Drug: DAOI-C group; Drug: Placebo oral capsule
Sponsors: Chang Gung Memorial Hospital; Ministry of Science and Technology, Taiwan
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Rifaximin 550 milligrams (MG)
Sponsors: Duke University; Bausch Health Americas, Inc.
Recruiting - Condition: Alzheimer's Disease
Intervention:
Sponsor: Dongzhimen Hospital, Beijing
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Drug: Daratumumab Injection
Sponsors: Marc L Gordon, MD; Janssen Scientific Affairs, LLC
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Control - Cognitive training in a practitioner's office one time per week; Behavioral: Experimental group 1 - Cognitive training in a practitioner's office one time per week and cognitive distance training one time per week; Behavioral: Experimental group 2 - Cognitive training in a practitioner's office one time per week and cognitive distance training four times per week
Sponsor: Hospices Civils de Lyon
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Placebo oral tablet; Drug: PTI-125 50 mg tablet; Drug: PTI-125 100 mg oral tablet
Sponsors: Cassava Sciences, Inc.; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Other: Clinical-neurological and neuropsychological tests; Diagnostic Test: Blood sampling; Other: Assessment of physical activity via fitness tracker/diary; Other: MRI-examinations
Sponsor: RWTH Aachen University
Recruiting - Condition: Alzheimer Disease, Early Onset
Interventions: Diagnostic Test: Overnight polysomnography; Diagnostic Test: blood sample; Diagnostic Test: high-resolution MRI scan; Behavioral: neuropsychological evaluation
Sponsors: University Hospital, Toulouse; Centre de Recherches sur la Cognition Animale (CRCA – UMR5169 CNRS/UPS); Centre de Recherche Cerveau & Cognition (CerCo – UMR5549 CNRS/UPS); Toulouse NeuroImaging Center (ToNIC – UMR 1214 Inserm/UPS); Fondation Plan Alzheimer; IHNPS/FHU HoPeS
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Diagnostic Test: 18-F-Flortaucipir
Sponsor: Mayo Clinic
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: COR388 capsule; Drug: Placebo capsule
Sponsor: Cortexyme Inc.
Recruiting - Condition: Early Alzheimer's Disease
Interventions: Drug: BAN2401; Drug: Placebo
Sponsors: Eisai Inc.; Biogen
Recruiting - Condition: Alzheimer Disease
Interventions: Device: transcranial alternating current stimulation; Device: sham stimulation
Sponsor: Xuanwu Hospital, Beijing
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: troriluzole; Drug: Placebo oral capsule
Sponsors: Biohaven Pharmaceuticals, Inc.; Alzheimer's Disease Cooperative Study (ADCS)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: High dose ANAVEX2-73; Drug: Mid dose ANAVEX2-73; Drug: Placebo oral capsule
Sponsors: Anavex Life Sciences Corp.; Anavex Australia Pty Ltd.
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Memantine; Drug: Placebo
Sponsor: University of California, San Diego
Recruiting - Condition: Alzheimer Disease
Intervention: Other: No intervention
Sponsors: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Hospital Clinic of Barcelona
Recruiting - Condition: Alzheimer Disease
Interventions: Diagnostic Test: cognitive assessment; Other: Inhibition evaluation; Other: Assessment of mental flexibility; Other: Evaluation of the update; Other: working memory; Other: episodic memory
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Other: Exposure to familiar songs; Other: Music Experience Questionnaire; Other: Implicit tasks memory; Other: Questionnaires
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Mild Alzheimer's Disease
Interventions: Drug: IONIS MAPTRx; Other: Placebo
Sponsor: Ionis Pharmaceuticals, Inc.
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: TRx0237
Sponsor: TauRx Therapeutics Ltd
Available - Condition: Alzheimer Disease
Intervention: Drug: XPro1595
Sponsors: Inmune Bio, Inc.; Alzheimer's Association
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: LPS
Sponsor: Yale University
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: DNL747; Drug: Placebo
Sponsor: Denali Therapeutics Inc.
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: RO7105705; Drug: Placebo; Drug: [18F]GTP1
Sponsor: Genentech, Inc.
Recruiting - Condition: Alzheimer Disease
Interventions: Dietary Supplement: Wismemo; Dietary Supplement: Placebo
Sponsors: GenMont Biotech Incorporation; Chang Gung Memorial Hospital
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Other: Non-tailored intervention group; Other: Culturally tailored intervention group
Sponsors: University of Colorado, Denver; Washington State University; University of Arizona
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Device: transcranial alternating current stimulation; Device: sham stimulation
Sponsor: Xuanwu Hospital, Beijing
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Vielight Neuro Gamma; Other: Sham Vielight Neuro Gamma
Sponsor: University of California, San Francisco
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: BPN14770; Drug: Placebo
Sponsor: Tetra Discovery Partners
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: [18F]P16-129
Sponsor: Five Eleven Pharma, Inc.
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: TRx0237 8 mg/day; Drug: Placebo; Drug: TRx0237 16 mg/day
Sponsor: TauRx Therapeutics Ltd
Recruiting - Condition: Alzheimer's Disease
Interventions: Dietary Supplement: Genistein; Other: Placebo
Sponsors: Fundación para la Investigación del Hospital Clínico de Valencia; University of Valencia
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Escitalopram Pill; Drug: Venlafaxine Pill; Drug: Placebo Oral Tablet
Sponsor: NYU Langone Health
Recruiting - Condition: Alzheimer Dementia
Intervention: Drug: Allopregnanolone
Sponsors: University of Southern California; University of Arizona; Alzheimer's Association
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: AMX0035; Drug: Placebo
Sponsors: Amylyx Pharmaceuticals Inc.; Alzheimer’s Drug Discovery Foundation; Alzheimer's Association
Recruiting - Condition: Alzheimer Disease
Interventions: Other: tablet therapy; Other: usual care
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Gantenerumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Conditions: Alzheimer Disease; Early Onset Alzheimer Disease
Intervention: Biological: AAVrh.10hPOE2 vector
Sponsor: Weill Medical College of Cornell University
Recruiting - Condition: Alzheimer Disease
Intervention: Procedure: Malnutrition screening and perioperative nutritional support
Sponsor: Hospices Civils de Lyon
Recruiting - Condition: Alzheimer's Disease
Interventions: Dietary Supplement: Ketogenic medium chain triglyceride drink (MCT drink); Dietary Supplement: Placebo
Sponsors: University of British Columbia; Université de Sherbrooke
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Meganatural-Az Grapeseed Extract; Drug: Placebo
Sponsors: Hillel Grossman; National Center for Complementary and Integrative Health (NCCIH)
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Gantenerumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Alzheimer's Disease
Intervention:
Sponsors: Washington University School of Medicine; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Montelukast buccal film; Other: Placebo buccal film
Sponsor: IntelGenx Corp.
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Crenezumab; Drug: Placebo; Other: [^18F]GTP1
Sponsors: Genentech, Inc.; Banner Alzheimer's Institute
Not yet recruiting - Condition: Alzheimer's Disease
Intervention: Device: Thymatron IV device (Somatics)
Sponsor: Central Institute of Mental Health, Mannheim
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Dronabinol (Marinol®); Drug: Placebo
Sponsors: Johns Hopkins University; Mclean Hospital
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: N-hydroxy-N'-phenyl-octanediamide (Vorinostat)
Sponsors: German Center for Neurodegenerative Diseases (DZNE); University Hospital, Bonn; University of Göttingen
Recruiting - Condition: Alzheimer Dementia
Intervention: Device: Immunoadsorption with Globaffin
Sponsor: University Medicine Greifswald
Recruiting - Condition: Alzheimer's Disease
Interventions: Device: rTMS active treatment; Device: rTMS sham treatment
Sponsor: University of Manitoba
Recruiting - Condition: Prodromal Alzheimer's Disease
Interventions: Other: Partnered Rhythmic Rehabilitation (PRR); Other: Group walking (WALK)
Sponsors: Emory University; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Alzheimer Disease; Alzheimer Disease, Early Onset
Interventions: Dietary Supplement: MitoQ; Dietary Supplement: Placebo
Sponsor: University of Nebraska, Omaha
Not yet recruiting - Condition: Alzheimer's Disease
Intervention:
Sponsors: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Obra Social La Caixa, Spain
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: F 18 T807
Sponsor: Washington University School of Medicine
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Donepezil patch; Drug: aricept Tab
Sponsor: Icure Pharmaceutical Inc.
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: DL-3-n-butylphthalide; Drug: Donepezil
Sponsor: First Affiliated Hospital Xi'an Jiaotong University
Recruiting - Condition: Alzheimer's Disease
Interventions: Radiation: 5 daily fractions of 2 Gy; Radiation: 10 daily fractions of 2 Gy
Sponsor: William Beaumont Hospitals
Recruiting - Condition: Dementia, Alzheimer Type
Interventions: Behavioral: Physical activity; Behavioral: Successful Aging
Sponsors: Pennington Biomedical Research Center; National Institute on Aging (NIA)
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: 11C-ER176; Drug: Florbetaben
Sponsor: William Charles Kreisl
Recruiting - Condition: Severe Alzheimer Disease
Interventions: Drug: GRF6019; Other: Placebo
Sponsor: Alkahest, Inc.
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: Longeveron Mesenchymal Stem Cells; Biological: Placebo
Sponsor: Longeveron LLC
Recruiting - Condition: Alzheimer Disease
Intervention: Other: Cognitive Stimulation (CS)
Sponsor: University of Roma La Sapienza
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: Levetiracetam
Sponsor: Walter Reed National Military Medical Center
Not yet recruiting - Condition: Alzheimer Disease, Early Onset
Intervention: Device: Theta-burst stimulation (TBS)
Sponsor: Chang Gung Memorial Hospital
Not yet recruiting - Condition: Early Onset Alzheimer Disease
Intervention: Diagnostic Test: Computer assisted ambulatory electroencephalogram
Sponsor: Mayo Clinic
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Azeliragon; Drug: Placebo
Sponsor: vTv Therapeutics
Recruiting - Condition: Alzheimer Disease, Early Onset
Interventions: Drug: AD-35 60mg group; Drug: AD-35 90mg group; Drug: Placebo group
Sponsors: Zhejiang Hisun Pharmaceutical Co. Ltd.; Medpace, Inc.
Recruiting - Conditions: Sleep; Alzheimer Disease
Interventions: Behavioral: Behavioral sleep education; Behavioral: Education only
Sponsor: University of California, Los Angeles
Recruiting - Condition: Alzheimer Dementia
Interventions: Drug: Human Mesenchymal Stem Cells and Lactated Riunger's Solution; Other: Placebo
Sponsors: Stemedica Cell Technologies, Inc.; Stemedica International SA
Recruiting - Condition: Alzheimer's Disease
Interventions: Radiation: 10 GY in 5 daily fractions; Radiation: 20 GY in 10 daily fractions
Sponsor: Virginia Commonwealth University
Recruiting - Conditions: Pain; Alzheimer Disease
Interventions: Behavioral: Auricular Point Acupressure; Behavioral: Education Control
Sponsor: Johns Hopkins University
Recruiting - Condition: Dementia Alzheimers
Intervention: Radiation: CT scan
Sponsor: Baycrest
Recruiting - Conditions: Alzheimer's Disease; Cardiovascular Risk Factors
Interventions: Other: optimal care of VRF; Other: standard care
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment
Interventions: Other: Acupuncture; Drug: Donepezil
Sponsors: Shanghai University of Traditional Chinese Medicine; Shanghai Mental Health Center; Huashan Hospital
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Other: Audio speech recording
Sponsor: East Tennessee State University
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: VX-745; Drug: placebo
Sponsors: University Hospital, Toulouse; Fondation Plan Alzheimer
Recruiting - Condition: Genetic Risk for Alzheimer's Disease
Interventions: Drug: donepezil HCL; Drug: Placebo
Sponsors: The Cleveland Clinic; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Cognitive Change
Intervention: Combination Product: Ebicomb
Sponsor: Neutec Ar-Ge San ve Tic A.Ş
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Device: Active Neuro RX Gamma device; Device: Sham Neuro RX Gamma device
Sponsor: Vielight Inc.
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Brexpiprazole
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; H. Lundbeck A/S
Recruiting - Conditions: Alzheimer Disease; Sleep
Interventions: Other: Multimodal brain imaging (MRI); Other: Actimetry; Other: Sleep Diary
Sponsor: University Hospital, Bordeaux
Not yet recruiting - Conditions: Alzheimer Disease; Sleep Apnea
Intervention: Diagnostic Test: PET Scan and nocturnal polysomnography
Sponsors: NYU Langone Health; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: L-Serine; Other: Placebo Gummy
Sponsors: Aleksandra Stark; Brain Chemistry Laboratories, Institute for Ethnomedicine
Recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Drug: Normal Saline along with standard treatment; Drug: PMZ-1620 (sovateltide) along with standard treatment
Sponsor: Pharmazz, Inc.
Recruiting - Conditions: Healthy; Alzheimer Disease
Interventions: Diagnostic Test: [F18]RO-948; Diagnostic Test: [F18]MK-6240; Diagnostic Test: [F18]AV1451
Sponsors: Johns Hopkins University; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Alzheimer Disease; Subjective Cognitive Impairment
Interventions: Other: Doppler ultrasonography; Other: Biospecimen collection
Sponsors: Assistance Publique - Hôpitaux de Paris; Fondation Plan Alzheimer; Naturalia & Biologia
Not yet recruiting - Conditions: Agitaton Associated With Alzheimer's Dementia; Alzheimer Dementia
Interventions: Drug: Brexpiprazole; Other: Placebo
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; H. Lundbeck A/S
Recruiting - Conditions: Alzheimer's Disease; Dementia
Interventions: Other: Placebo; Other: Medication Therapy Management (MTM); Drug: Scopolamine patch
Sponsors: Daniela Moga; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Dementia, Alzheimer Type; Deep Brain Stimulation
Interventions: Device: Deep brain stimulation; Drug: Best medical treatment for Alzheimer's disease
Sponsors: Buddhist Tzu Chi General Hospital; Beijing Tiantan Hospital
Recruiting - Conditions: Alzheimer's Disease; Healthy Volunteer
Interventions: Drug: BIIB076; Drug: Placebo
Sponsor: Biogen
Recruiting - Condition: Alzheimer's Dementia With Behavioral Disturbance
Intervention: Device: Acupuncture needle
Sponsor: Massachusetts General Hospital
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Photobiomodulation REGEnLIFE RGn530 device; Device: SHAM REGEnLIFE RGn530 device
Sponsor: University Hospital, Montpellier
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Interventions: Behavioral: Memory Training; Behavioral: Kundalini yoga and meditation
Sponsor: University of California, Los Angeles
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment
Interventions: Drug: Nicotinamide; Drug: Placebo Comparator
Sponsor: University of California, Irvine
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment
Interventions: Behavioral: Routine care; Other: Coaching plus routine care
Sponsors: Hoag Memorial Hospital Presbyterian; Institute for Systems Biology; Arivale
Recruiting - Conditions: Early Onset Alzheimer Disease; Alzheimer Disease; Mild Cognitive Impairment
Interventions: Drug: Flortaucipir; Drug: Florbetaben
Sponsors: Liana Apostolova; Alzheimer's Therapeutic Research Institute; National Institute on Aging (NIA); Alzheimer's Association
Recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: Aerobic exercise; Behavioral: Stretch and Strength
Sponsors: University of Calgary; Canadian Institutes of Health Research (CIHR)
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: ACP Specialist Program
Sponsors: Indiana University; National Institute on Aging (NIA); Hebrew SeniorLife; Regenstrief Institute, Inc.
Not yet recruiting - Conditions: Mild Cognitive Impairment (MCI); Alzheimer's Disease (AD)
Intervention:
Sponsors: University of Southern California; Northern California Institute of Research and Education; National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute
Recruiting - Conditions: Alzheimer Dementia; Agitation,Psychomotor
Interventions: Device: Electroconvulsive Therapy (ECT); Other: Simulated Electroconvulsive Therapy (S-ECT)
Sponsors: Brent Forester; Mayo Clinic; Pine Rest Christian Mental Health Services; Emory University; The Zucker Hillside Hospital; Medical University of South Carolina
Not yet recruiting - Conditions: Alzheimer Disease; Cognitive Decline
Interventions: Drug: [18F]AV-1451; Procedure: Positron Emission Tomography
Sponsor: Neil M Rofsky, MD, MHA
Not yet recruiting - Conditions: Alzheimer Disease; Olfaction Disorders
Intervention: Diagnostic Test: Olfactory test
Sponsor: Jewish General Hospital
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: Drug: Placebo; Drug: AVP-786
Sponsor: Avanir Pharmaceuticals
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Intervention: Drug: Pramlintide challenge test
Sponsors: Boston University; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Transcranial Magnetic Stimulation; Magnetic Resonance Imaging; Alzheimer Disease
Intervention: Other: transcranial magnetic stimulation
Sponsor: Anhui Medical University
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Mediterranean Diet; Dietary Supplement: Study Supplement; Behavioral: Low-fat Diet
Sponsors: University of Kansas Medical Center; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: levetiracetam
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting - Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) PatientsConditions: Alzheimer Disease; Parkinson Disease
Interventions: Drug: Metabolic Cofactor Supplementation; Drug: Sorbitol
Sponsors: Istanbul Medipol University Hospital; ScandiBio Therapeutics AB; Alanya Alaaddin Keykubat University; Sahlgrenska University Hospital, Sweden; KTH Royal Institute of Technology
Not yet recruiting - Conditions: Alzheimers Disease; Dementia; Alzheimers Disease, Familial
Interventions: Drug: Gantenerumab; Drug: Solanezumab; Drug: Matching Placebo (Gantenerumab); Drug: Matching Placebo (Solanezumab)
Sponsors: Washington University School of Medicine; Eli Lilly and Company; Hoffmann-La Roche; Alzheimer's Association; National Institute on Aging (NIA); Avid Radiopharmaceuticals; Accelerating Medicines Partnership (AMP); Janssen, LP
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment
Interventions: Drug: MK-4334; Drug: Placebo to MK-4334; Drug: Donepepzil
Sponsor: Merck Sharp & Dohme Corp.
Not yet recruiting - Conditions: Dementia; Alzheimer Disease 1; Alzheimer Disease 2; Alzheimer Disease 3
Interventions: Drug: APH-1105; Other: Placebo
Sponsor: Aphios
Not yet recruiting - Conditions: Alzheimer Disease; Intestinal Microbiota
Intervention: Procedure: Fecal sample collection
Sponsor: Nantes University Hospital
Recruiting - Condition: Agitation Associated With Dementia of the Alzheimer's Type
Intervention: Drug: Brexpiprazole
Sponsor: Otsuka Pharmaceutical Co., Ltd.
Recruiting - Conditions: Down Syndrome; Alzheimer Disease
Intervention: Procedure: Neuro-imaging, Lumbar puncture
Sponsor: Institut Jerome Lejeune
Recruiting - Condition: Agitation Associated With Dementia of the Alzheimer's Type
Interventions: Drug: Brexpiprazole; Drug: Placebo
Sponsor: Otsuka Pharmaceutical Co., Ltd.
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; MCI With Increased Risk for Alzheimer Disease
Interventions: Behavioral: Music lessons; Behavioral: Training intervention
Sponsors: University of Bergen; NORCE Norwegian Research Centre AS; Bergen Municipality
Recruiting - Conditions: Mild to Moderate Dementia Due to Alzheimer's Disease; With or Without Coexisting Cerebrovascular Disease
Interventions: Drug: RPh201; Other: Placebo
Sponsor: Regenera Pharma Ltd
Recruiting - Conditions: Alzheimer Disease; Late Onset Alzheimer Disease; Dementia
Intervention:
Sponsors: Indiana University; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: 18F-AV-1451
Sponsor: Washington University School of Medicine
Recruiting - Conditions: Mild Cognitive Impairment; Mild Alzheimer's Disease
Interventions: Drug: Dabigatran; Drug: Placebo - Cap
Sponsors: University of Rhode Island; Alzheimer’s Drug Discovery Foundation; Boehringer Ingelheim
Not yet recruiting - Conditions: Mild Cognitive Impairment; Prodromal Alzheimer's Disease
Interventions: Drug: Placebo Oral Tablet; Drug: AGB101 220 mg tablet
Sponsors: AgeneBio; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Disruptive Behavior
Interventions: Drug: Prazosin; Drug: Placebo oral capsule
Sponsors: Alzheimer's Disease Cooperative Study (ADCS); National Institute on Aging (NIA); VA Puget Sound Health Care System
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: icosapent ethyl (IPE); Other: gel cap placebo
Sponsors: VA Office of Research and Development; University of Wisconsin, Madison
Recruiting - Conditions: Alzheimer Disease; Diabetes Mellitus, Type 2
Intervention: Device: Tailored Lighting Intervention
Sponsors: Rensselaer Polytechnic Institute; Icahn School of Medicine at Mount Sinai
Recruiting - Condition: Alzheimer Disease
Interventions: Diagnostic Test: Measure of OxPhos upregulation; Diagnostic Test: lactate (measured with 1H-MRSI)
Sponsor: NYU Langone Health
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Intervention: Drug: AVP-786
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Psychosocial intervention; Other: Pharmaceutical care and psychosocial support
Sponsor: Hospices Civils de Lyon
Recruiting - Conditions: Alzheimer Disease; Cerebral Amyloid Angiopathy
Interventions: Other: EVOO; Other: OO
Sponsor: Auburn University
Recruiting - Condition: Alzheimer Disease
Interventions: Biological: Regulatory T cells; Other: Saline
Sponsors: GMP BIO Co., LTD.; BHT Lifescience Austrailia Pty Ltd.
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Device: REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION
Sponsor: I.R.C.C.S. Fondazione Santa Lucia
Recruiting - Condition: Alzheimer Disease
Interventions: Dietary Supplement: MMFS-205-SR; Dietary Supplement: Placebo
Sponsors: Neurocentria, Inc.; Ohio State University
Recruiting - Conditions: Alzheimer Disease; Neurodegenerative Diseases; Dementia
Intervention: Behavioral: Mindfulness Based Health Care (MBHC) Program
Sponsor: Universidad Miguel Hernandez de Elche
Recruiting - Condition: Alzheimer Disease
Interventions: Device: GRASP DCE-MRI; Device: 3T Brain Scan
Sponsor: NYU Langone Health
Recruiting - Conditions: Down Syndrome; Alzheimer Disease
Interventions: Behavioral: Remote Low; Behavioral: Remote High; Behavioral: Personal Coach
Sponsors: University of Kansas Medical Center; National Institute on Aging (NIA)
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Procedure: PET-MR Scan; Drug: PiB
Sponsors: NYU Langone Health; Icahn School of Medicine at Mount Sinai
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Active Treatment- CT1812 100 mg; Drug: Placebo; Drug: Active Treatment- CT1812 300 mg
Sponsor: Cognition Therapeutics
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Guanfacine; Drug: Placebo
Sponsor: Imperial College London
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Neuro RX Gamma synchronous; Device: Sham; Device: Neuro RX Gamma asynchronous
Sponsor: Vielight Inc.
Recruiting - Conditions: Cognitive Deficits; Alzheimer Disease
Intervention: Procedure: Acupunture
Sponsor: N & S Neurology Center, A Medical Group, Inc
Not yet recruiting - Condition: Early Alzheimer's Disease
Interventions: Drug: PQ912; Other: Placebo
Sponsors: Probiodrug AG; Alzheimer's Disease Cooperative Study (ADCS); National Institute on Aging (NIA)
Not yet recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Prediabetic State
Intervention:
Sponsor: Wake Forest University Health Sciences
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Alzheimer's Disease; Dementia
Interventions: Behavioral: Behavioral Activation; Behavioral: Information and Support
Sponsors: University of California, San Diego; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease, Early Onset
Interventions: Drug: Levetiracetam; Drug: Placebo oral capsule
Sponsor: Beth Israel Deaconess Medical Center
Recruiting - Conditions: Vestibular Diseases; Vestibular Disorder; Alzheimer Disease
Interventions: Behavioral: Vestibular physical therapy; Behavioral: Active control
Sponsor: Johns Hopkins University
Not yet recruiting - Condition: Preclinical Alzheimer's Disease
Intervention: Behavioral: Exergame
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - Condition: Alzheimer Disease, Early Onset
Intervention: Drug: Sustiva Pill
Sponsors: Case Western Reserve University; University Hospitals Cleveland Medical Center; Massachusetts General Hospital
Recruiting - Conditions: Alzheimer Disease; Herpes Simplex 1; Herpes Simplex 2
Interventions: Drug: Valacyclovir; Drug: Placebo
Sponsors: New York State Psychiatric Institute; National Institutes of Health (NIH); National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Intervention: Behavioral: Family-centered Function-focused Care (Fam-FFC)
Sponsors: Penn State University; National Institutes of Health (NIH)
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment, Mild; Dementia, Mild
Interventions: Behavioral: Smartphone Personal Assistant; Behavioral: Implementation Intention
Sponsors: Baylor University; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Subjective Cognitive Decline
Intervention: Other: No intervention
Sponsor: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Recruiting - Conditions: Cognitively Normal; Mild Cognitive Impairment; Alzheimer Disease
Intervention: Drug: [18F]PI-2620
Sponsor: Jae Seung Kim
Recruiting - Conditions: Alzheimer's Disease; Obstructive Sleep Apnea
Intervention:
Sponsor: Sociedad Española de Neumología y Cirugía Torácica
Recruiting - Condition: Mild to Moderate Alzheimer's Disease
Interventions: Drug: 400mg LM11A-31-BHS; Drug: 800mg LM11A-31-BHS; Drug: Placebos
Sponsors: PharmatrophiX Inc.; National Institute on Aging (NIA)
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease; Type2 Diabetes
Intervention: Device: Tailored Lighting Intervention
Sponsors: Rensselaer Polytechnic Institute; Icahn School of Medicine at Mount Sinai
Recruiting - Conditions: Vestibular Diseases; Alzheimer Disease; Cognitive Impairment
Intervention: Behavioral: Vestibular Physical Therapy
Sponsors: University of Pittsburgh; Johns Hopkins University
Recruiting - Condition: Dementia, Alzheimer Type
Interventions: Behavioral: ABC Clinical Program; Behavioral: HABC 2.0
Sponsors: Richard Holden; Indiana University
Not yet recruiting - Conditions: Alzheimer Disease; Down Syndrome; Mild Cognitive Impairment
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Conditions: Memory Disorders; Mild Cognitive Impairment; Alzheimer's Disease
Interventions: Behavioral: Intervention Group; Behavioral: Control Group
Sponsors: Boston University; Wallace H. Coulter Foundation
Recruiting - Conditions: Alzheimer's Disease; Obstructive Sleep Apnea; Sleep Disturbances
Intervention:
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Recruiting - Conditions: Alzheimer Disease; Alzheimer Disease, Late Onset; Memory Loss; Patient Education as Topic
Intervention: Behavioral: Web-based education
Sponsor: Weill Medical College of Cornell University
Recruiting - Conditions: Alzheimer's Disease; Psychosis; Agitation
Interventions: Drug: Lithium; Drug: Placebo
Sponsors: New York State Psychiatric Institute; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Parkinson's Disease; Frontotemporal Lobar Degeneration
Intervention: Behavioral: Observational Study
Sponsor: University Health Network, Toronto
Recruiting - Conditions: Atypical Alzheimer's Disease; Logopenic Progressive Aphasia (LPA); Posterior Cortical Atrophy (PCA)
Interventions: Drug: F-18 AV 1451; Drug: C-11 PiB
Sponsor: Mayo Clinic
Recruiting - Condition: Alzheimer's Disease (AD)
Interventions: Drug: CKD-355A (D797/Memantine HCl 20mg); Drug: CKD-355B (D797/Memantine HCl 20mg); Drug: D797; Drug: D324 (Memantine HCl 10mg)
Sponsor: Chong Kun Dang Pharmaceutical
Not yet recruiting - Conditions: Blood Brain Barrier; Alzheimer Disease; Cognitive Dysfunction; Dementia
Intervention: Diagnostic Test: Contrast agent enhanced MRI using Gadovist
Sponsors: Charite University, Berlin, Germany; Prof. Dr. med. Jochen Fiebach (Senior Physician)
Recruiting - Conditions: Alzheimer's Disease; Lewy Body Dementia; Parkinson's Disease
Interventions: Radiation: DaTscan; Radiation: F18-AV-45; Radiation: FDG-PET; Genetic: APOE genotype; Procedure: Polysomnogram; Behavioral: Clinical Assessment
Sponsors: Douglas Scharre; Avid Radiopharmaceuticals; Mangurian Foundation
Recruiting - Conditions: Alzheimer Disease; Healthy Volunteers
Interventions: Drug: [18F] MNI-946; Drug: [18F]Florbetapir
Sponsor: Invicro
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Mild Dementia; Aging; Cognitive Change
Interventions: Other: Retinal Imaging; Other: Pupillometry; Other: Contrast Sensitivity; Diagnostic Test: Neuropsychological Evaluation; Genetic: APOE genotyping; Other: blood draw; Other: Gait Assessment; Other: Actigraphy
Sponsors: University of Rhode Island; Stuart Sinoff, MD; Peter J Snyder, MD; BayCare Health System
Not yet recruiting - Conditions: Elderly; Alzheimer Disease
Interventions: Procedure: Actigraphy; Procedure: Nocturnal Polysomnograpahy (NPSG)
Sponsors: NYU Langone Health; NIH/NIA
Recruiting - Conditions: Healthy; Alzheimer Disease
Interventions: Biological: AL003; Other: Saline Solution
Sponsor: Alector Inc.
Recruiting - Conditions: Delirium; Alzheimer Disease
Interventions: Behavioral: Physical Exercise Intervention; Behavioral: Cognitive Training Intervention; Behavioral: Stretching Control; Behavioral: Cognitive Control
Sponsor: Indiana University
Recruiting - Conditions: Healthy; Alzheimer Disease
Interventions: Biological: AL002; Other: Saline Solution
Sponsor: Alector Inc.
Recruiting - Conditions: Alzheimer Disease; Anxiety; Agitation,Psychomotor
Intervention: Drug: high CBD/low THC sublingual solution
Sponsors: Mclean Hospital; Spier Family Foundation
Not yet recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease
Intervention:
Sponsors: Catholic University of the Sacred Heart; Ministry of Health, Italy; Agenzia Italiana del Farmaco
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Interventions: Other: low carbohydrate/high fat diet; Other: low fat/high carbohydrate diet
Sponsors: Wake Forest University Health Sciences; National Institute on Aging (NIA)
Recruiting - Conditions: Brain Imaging; Mild Cognitive Impairment; Alzheimer Disease; Deep Brain Stimulation
Interventions: Device: Excitation; Device: Inhibition
Sponsor: University of California, Los Angeles
Recruiting - Condition: Pain
Intervention: Behavioral: Thermal stimulation
Sponsor: University of Aarhus
Recruiting - Conditions: Alzheimer Disease; Primary Progressive Aphasia; Mild Cognitive Impairment
Intervention: Device: repetitive transcranial magnetic stimulation (rTMS)
Sponsor: Brigham and Women's Hospital
Recruiting - Conditions: Cognitive Aging; Alzheimer Disease, Protection Against
Interventions: Device: Active NIR-PBM; Device: Sham NIR-PBM
Sponsors: University of Florida; University of Arizona; National Institute on Aging (NIA)
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Diagnostic Test: CSF drawing during spinal anaesthesia; Diagnostic Test: Fasting blood sample; Diagnostic Test: Lumbar puncture
Sponsor: University Hospital, Lille
Recruiting - Conditions: Sleep; Alzheimer Disease; Cognitive Impairment; Aging; CBT
Interventions: Behavioral: Sleep intervention; Behavioral: Placebo intervention
Sponsor: University of California, San Francisco
Not yet recruiting - Conditions: Blood Brain Barrier Defect; Sleep Deprivation; Sleep Apnea; Alzheimer Disease
Intervention: Diagnostic Test: Diagnostic Test
Sponsors: Charite University, Berlin, Germany; Arda Can Cetindag; Lukas Preis
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease
Interventions: Biological: ABvac40; Biological: Placebo
Sponsor: Araclon Biotech S.L.
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: NNI-362; Drug: Placebo
Sponsors: Neuronascent, Inc.; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Tricaprilin; Drug: Placebo
Sponsor: Cerecin
Recruiting - Condition: Alzheimers Disease
Interventions: Drug: RO7126209; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Dementia
Interventions: Drug: Escitalopram; Drug: Placebo
Sponsors: JHSPH Center for Clinical Trials; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: F 18 T807 Flortaucipir
Sponsor: Washington University School of Medicine
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Device: NEUROLITH
Sponsors: Storz Medical AG; Medical University of Vienna
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Self-Guided Lifestyle Intervention; Behavioral: Structured Lifestyle Intervention
Sponsors: Wake Forest University Health Sciences; Alzheimer's Association
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: PU-AD; Drug: Placebo
Sponsor: Samus Therapeutics, Inc.
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Flicker
Sponsors: Emory University; Georgia Institute of Technology
Recruiting - Study to Assess the Safety, Tolerability and Pharmacokinetics of Single Ascending Oral Doses of J147Condition: Alzheimer's Disease
Interventions: Drug: J147; Drug: Placebo
Sponsors: Abrexa Pharmaceuticals, Inc.; Iqvia Pty Ltd
Recruiting - Condition: Brain DHA Delivery and Alzheimer's Disease Risk
Interventions: Drug: DHA; Drug: Placebo
Sponsors: University of Southern California; Huntington Medical Research Institutes; National Institute on Aging (NIA); Alzheimer’s Drug Discovery Foundation
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Telmisartan 20mg; Drug: Telmisartan 40mg; Drug: Placebo
Sponsor: Emory University
Recruiting - Conditions: Sleep; Sleep Disorders; Insomnia; Alzheimer's Disease
Interventions: Drug: Zolpidem; Drug: Zoplicone; Drug: Placebo
Sponsor: Brasilia University Hospital
Recruiting - Condition: Healthy Participants
Interventions: Other: No Practice Effects (NPE) cognitive battery, and Miami Computerized Functional Assessment Scale (CFAS); Other: Preclinical Alzheimer's Cognitive Composite (PACC), Alzheimer's Disease Assessment Scale-Cognitive Scale (ADAS-Cog), and Functional Assessment Questionnaire (FAQ)
Sponsors: New York State Psychiatric Institute; Columbia University; University of Southern California; Feinstein Institute for Medical Research; University of Miami
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Placebo; Drug: Candesartan
Sponsor: Emory University
Recruiting - Condition: APOE 4
Interventions: Drug: AGB101 220 mg; Other: Placebo
Sponsors: Medical College of Wisconsin; National Institute on Aging (NIA)
Recruiting - Condition: Caregiver
Interventions: Behavioral: Intervention Condition; Behavioral: Control Condition
Sponsors: Weill Medical College of Cornell University; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Chinese University of Hong Kong
Recruiting - Conditions: Alzheimer Disease; Cognitive Dysfunction; Mild Cognitive Impairment; Mild Dementia; Cognitive Decline; Dementia, Alzheimer Type
Intervention: Device: Renew NCP-5
Sponsors: Renew Research, LLC; KAI Research
Recruiting - Condition: Alzheimer Disease
Interventions: Dietary Supplement: Omega-3 treatment; Dietary Supplement: Placebo
Sponsor: University Hospital, Toulouse
Recruiting - Condition: Alzheimer Disease
Interventions: Other: transdisciplinary approach; Other: multidisciplinary approach
Sponsors: University of Pittsburgh; Patient-Centered Outcomes Research Institute
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Group-based Cognitive Behavioral Therapy (CBT); Behavioral: Phone-based Cognitive Behavioral Therapy (CBT)
Sponsors: Emory University; Alzheimer's Association
Recruiting - Condition: Alzheimer Dementia
Interventions: Behavioral: Perspective Taking Reappraisal; Other: Basic Skill Building
Sponsor: The Hong Kong Polytechnic University
Recruiting - Condition: Alzheimer's Disease
Intervention: Device: Actigraph
Sponsor: NYU Langone Health
Not yet recruiting - Condition: Dementia Alzheimers
Intervention: Other: This is not an intervention study
Sponsors: University of Edinburgh; Keele University
Not yet recruiting - Condition: Healthy Cognition
Interventions: Other: Exercise Training; Other: Flexibility Control
Sponsors: University of Maryland, College Park; National Institute on Aging (NIA); Johns Hopkins University; Marquette University
Recruiting - Association Between Cerebral Arterial Vascular Flow and Sleep Apnea in Neurodegenerative AlterationsCondition: Alzheimer Disease
Intervention: Other: Vascular flow measurement by PC-MRI
Sponsor: Central Hospital Saint Quentin
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia
Intervention: Other: Blood collection, PiB PET/MRI, and cognitive testing
Sponsor: Washington University School of Medicine
Recruiting - Condition: Dementia
Intervention: Behavioral: Music and Memory
Sponsors: Brown University; Westat; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Burnout, Caregiver; Quality of Life
Intervention: Behavioral: Heart Rate Variability Biofeedback Training
Sponsor: Arizona State University
Recruiting - Condition: Epilepsy
Intervention: Biological: profile of CSF biomarkers of AD
Sponsor: Hospices Civils de Lyon
Recruiting - Conditions: Agitation in Patients With Dementia of the Alzheimer's Type; Alzheimer Disease; Agitation,Psychomotor
Interventions: Drug: AXS-05; Drug: Bupropion; Drug: Placebo
Sponsor: Axsome Therapeutics, Inc.
Recruiting - Condition: Age-related Cognitive Decline
Interventions: Behavioral: Cognitive Training; Behavioral: Computerized Cognitive Stimulation
Sponsors: University of South Florida; Michigan State University; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Vascular Dementia; Lewy Body Disease; Lewy Body Dementia With Behavioral Disturbance (Disorder); Dementia, Mixed; Parkinson-Dementia Syndrome; Chronic Traumatic Encephalopathy; Huntington's Dementia; Wernicke Korsakoff Syndrome; Traumatic Brain Injury; Dementia, Multi-Infarct; Autism; Autism Spectrum Disorder; Autistic Behavior; Autistic Disorder, Current or Active State; Cadasil; LATE Limbic-predominant Age-related TDP-43 Encephalopathy
Interventions: Procedure: Intravenous Bone Marrow Stem Cell (BMSC) Fraction; Procedure: Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction; Procedure: Near Infrared Light
Sponsor: MD Stem Cells
Recruiting - Conditions: Alzheimer Disease; MCI; Aging
Intervention: Diagnostic Test: Neuropsychological tests
Sponsor: South Tees Hospitals NHS Foundation Trust
Recruiting - Conditions: Alzheimer Disease, Early Onset; Alzheimer Disease; Alzheimer Disease, Late Onset; Dementia, Alzheimer Type; Logopenic Progressive Aphasia; Primary Progressive Aphasia; Visuospatial/Perceptual Abilities; Posterior Cortical Atrophy; Executive Dysfunction; Corticobasal Degeneration; Ideomotor Apraxia
Intervention:
Sponsors: University of California, Los Angeles; National Institute on Aging (NIA); University of Southern California
Recruiting - Condition: Alzheimer Dementia
Interventions: Drug: Methylphenidate Extended Release Oral Capsule; Other: Placebo
Sponsor: Massachusetts General Hospital
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Healthy Volunteers
Intervention: Drug: [18F]MNI-1126
Sponsor: Invicro
Recruiting - Conditions: Healthy Volunteers; Alzheimer Disease; Progressive Supranuclear Palsy
Intervention: Drug: [18F]MNI-958
Sponsor: Invicro
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Curcumin; Behavioral: aerobic yoga; Behavioral: non aerobic yoga; Dietary Supplement: Placebo
Sponsor: VA Office of Research and Development
Recruiting - Condition: Dementia
Intervention: Other: Educational Materials - Patient & Clinician
Sponsors: Kaiser Permanente; Johns Hopkins University; Duke University; University of South Australia
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease
Intervention: Behavioral: Cognitive tests
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Cancer, Breast
Interventions: Behavioral: DECAD decision aid; Other: Home safety guide
Sponsor: Indiana University
Recruiting - Condition: Dementia
Interventions: Behavioral: Old SCHOOL Hip-Hop; Behavioral: My Plate
Sponsor: Columbia University
Recruiting - Condition: Mild Cognitive Impairment
Intervention: Other: No intervention
Sponsor: Sun Yat-sen University
Recruiting - Conditions: Alzheimer Disease; Battery
Interventions: Drug: Memantine; Drug: Placebo
Sponsor: University Hospital, Lille
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Dementia
Intervention: Device: Muscle relaxation using full body massage machine
Sponsor: Samsung Medical Center
Recruiting - Conditions: Functional Aging; Subjective Cognitive Concerns; Compensation Strategies; Brain Health Activities
Intervention: Behavioral: Intervention
Sponsor: University of California, Davis
Recruiting - Condition: Mild Cognitive Impairment
Intervention: Device: Transcranial magnetic stimulation
Sponsors: Masaryk University; St. Anne's University Hospital Brno, Czech Republic
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Intervention: Behavioral: ReCODE Protocol
Sponsor: QuesGen Systems Inc
Recruiting - Conditions: Alzheimer's Disease; Brain Diseases; Central Nervous System Diseases; Delirium, Dementia, Amnestic, Cognitive Disorders; Dementia; Mental Disorders; Nervous System Diseases; Neurodegenerative Diseases; Tauopathies
Intervention: Other: L-Leucine 13C6
Sponsors: Washington University School of Medicine; BrightFocus Foundation; National Institutes of Health (NIH)
Recruiting - Conditions: Cognitively Normal Older Adults; Hypertension; Subjective Cognitive Decline; Family History of Alzheimer's Disease
Interventions: Drug: Angiotensin II receptor blocker (ARB, losartan) and calcium channel blocker (CCB, amlodipine); Behavioral: Aerobic Exercise Training; Other: Usual Care; Behavioral: Stretching Exercise; Drug: Atorvastatin
Sponsors: University of Texas Southwestern Medical Center; Texas Health Resources; University of Kansas Medical Center; Washington University School of Medicine; Pennington Biomedical Research Center; Michigan State University
Recruiting - Conditions: Alzheimer Disease; HIV
Intervention: Drug: F 18 T807
Sponsor: Washington University School of Medicine
Recruiting - Conditions: Alzheimer Disease; ELECTROENCEPHALOGRAPHIC VARIANT PATTERN 1 (Disorder)
Intervention: Other: Rapid Visual Information Processing (RVIP) test
Sponsor: University Hospital, Lille
Recruiting - Conditions: Alzheimer's Disease; Dementia
Interventions: Other: Online counseling via Zoom teleconferencing; Other: Telephone support as needed
Sponsor: NYU Langone Health
Recruiting - Conditions: Alzheimer's Disease (Incl Subtypes); Cognitive Impairment
Intervention: Behavioral: Enhanced psycho-education about dementia and caregiving
Sponsors: University of California, Davis; National Institute on Aging (NIA); Alzheimer's Association
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease
Interventions: Other: tDCS; Other: Exercise; Other: Exercise Education; Other: Sham tDCS
Sponsor: Sunnybrook Health Sciences Centre
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Interventions: Behavioral: Data-Driven Clinical Recommendations; Behavioral: Coached Data-Driven Clinical Recommendations
Sponsors: John Wayne Cancer Institute; Institute for Systems Biology; St. Joseph's Healthcare Foundation
Recruiting - Conditions: Dementia; Dysphagia
Interventions: Device: Isometric tongue strengthening; Drug: Biotene
Sponsor: University of Wisconsin, Madison
Not yet recruiting - Conditions: Bipolar Disorder; Alzheimer's Disease
Interventions: Procedure: lumbar puncture (LP); Procedure: brain MRI
Sponsor: University Hospital, Grenoble
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Retinal Vascular; Parkinson Disease; Multiple Sclerosis; Huntington Disease; Neuro-Degenerative Disease
Intervention: Device: Retinal Imaging
Sponsors: Duke University; Alzheimer’s Drug Discovery Foundation; University of Edinburgh
Recruiting - Conditions: Mild Cognitive Impairment; Biomarker; Diagnosis; Treatment
Interventions: Drug: Huperzine A; Drug: Placebo
Sponsor: Shanghai Mental Health Center
Not yet recruiting - Conditions: Sedentary Lifestyle; Stress, Psychological
Intervention: Behavioral: Exergame Experience
Sponsors: Brandeis University; National Institute on Aging (NIA)
Recruiting - Conditions: Dementia; Infection, Bacterial
Intervention: Behavioral: TRAIN-AD
Sponsor: Hebrew Rehabilitation Center, Boston
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention: Device: Transcranial direct current stimulation (tDCS) Soterix Medical Inc. tDCS unit
Sponsor: VA Office of Research and Development
Recruiting - Condition: Cognitive Disorders
Intervention: Other: Adapted physical activity
Sponsor: Centre Hospitalier Universitaire de Nice
Not yet recruiting - Conditions: Patients Aged 65-85 (Both Included); Diagnosed of Mild Cognitive Impairment; Diagnosed of Type 2 Diabetes in Active Treatment (Hypoglycemic Agents) for a Period ≥5 Years
Interventions: Device: Smart pillbox; Other: Interactive digital platform
Sponsors: Parc Sanitari Pere Virgili; Hospital Vall d'Hebron; Consorci Sanitari de Terrassa; Fundació Recerca Mútua Terrassa (FMT); Clínica Universitària de la Fundació Universitària del Bages (FUB); Althaia Xarxa Assistencial Universitària de Manresa; Fundació Privada Hospital Asil de Granollers (HAG); Consorci Hospitalari de Vic; LambdaLoopers; Universitat Politècnica de Catalunya; Leitat; Mixestat; Meditecnologia
Recruiting - Conditions: Cognition Disorder; Alzheimer Disease
Interventions: Other: MMSE (mini mental state examination); Other: SAGE (Self-Administered Gerocognitive Exam)
Sponsor: Centre Hospitalier Universitaire, Amiens
Not yet recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Intervention: Behavioral: PlanYourLifespan.org
Sponsors: Northwestern University; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: MEMORI Corps program; Other: Augmented Waitlist Control
Sponsors: Johns Hopkins University; Alzheimer's Association; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: Personalized care network
Sponsor: University of Washington
Not yet recruiting - Feasibility and Efficacy of Dietary Interventions for Older Adults With Subjective Cognitive DeclineConditions: Alzheimer Disease; Cognitive Impairment
Interventions: Dietary Supplement: MAD; Dietary Supplement: MIND
Sponsor: Johns Hopkins University
Not yet recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: Innovations in Dementia Empowerment and Action (IDEA); Behavioral: Reducing Disabilities in Alzheimer's Disease (RDAD)
Sponsor: University of Washington
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Intervention: Diagnostic Test: [18F]flutemetamol PET scan
Sponsors: University of Utah; National Institutes of Health (NIH)
Recruiting - Conditions: Alzheimer Disease; Neurodegenerative Diseases
Intervention: Diagnostic Test: Cytology and Immunohistochemistry
Sponsor: University of Arkansas
Recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: Tele-Savvy; Behavioral: Healthy Living Education Program
Sponsors: Emory University; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: The Residential Care Transition Module
Sponsors: University of Minnesota - Clinical and Translational Science Institute; Johns Hopkins University; NYU Langone Health; Benjamin Rose Institute; Emory University
Recruiting - Conditions: Dementia; Alzheimer Disease
Intervention: Drug: Herbal medicine
Sponsor: Taipei Veterans General Hospital, Taiwan
Not yet recruiting - Conditions: Cognitive Impairment; Alzheimer Disease
Intervention: Diagnostic Test: MemScreen
Sponsor: MemScreen
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention: Device: Lighting Intervention
Sponsor: Rensselaer Polytechnic Institute
Not yet recruiting - Conditions: Cognitive Impairment; Alzheimer Disease
Interventions: Drug: THN 201; Drug: Donepezil; Drug: Placebo
Sponsor: Theranexus
Recruiting - Conditions: Family; Alzheimer Dementia
Intervention: Behavioral: SCP Plus
Sponsors: The University of Texas at Arlington; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Fronto-temporal Lobar Dementia
Intervention: Other: Questionnary and IRM
Sponsor: University Hospital, Strasbourg, France
Recruiting - Conditions: Dementia; Alzheimer's Disease
Interventions: Behavioral: UCF Caregiver Support Group; Behavioral: Community Support Groups
Sponsors: University of Central Florida; Alzheimer's and Dementia Resource Center
Recruiting - Conditions: Apathy; Alzheimer's Disease
Interventions: Drug: Methylphenidate; Drug: Placebo
Sponsors: Johns Hopkins Bloomberg School of Public Health; National Institute on Aging (NIA)
Recruiting - Conditions: Presbycusis, Bilateral; Alzheimer Disease 2 Due to Apoe4 Isoform
Interventions: Device: Audiologist-based fitting; Device: Service-only Fitting; Device: Device-only fitting
Sponsors: Yu-Hsiang Wu; Vanderbilt University Medical Center; National Institute on Deafness and Other Communication Disorders (NIDCD)
Not yet recruiting - Condition: Sleep Disorder
Interventions: Diagnostic Test: Structural 3T MRI; Diagnostic Test: MRI Based Perfusion Imaging; Diagnostic Test: VR-CO2 MRI Scans
Sponsor: NYU Langone Health
Recruiting - Conditions: Alzheimer's Disease; Alzheimer Dementia (AD); Aggression
Interventions: Behavioral: Non-Pharmacological Intervention; Other: Pharmacological Intervention
Sponsors: Centre for Addiction and Mental Health; University of Calgary; Lawson Health Research Institute; Douglas Mental Health University Institute
Recruiting - Conditions: Diabetic Retinopathy (DR); Age-related Macular Degeneration (AMD); Mid-peripheral Drusen Formation; Diabetic Macular Edema (DME)
Interventions: Behavioral: Photobiomodulation; Behavioral: Ketogenic diet
Sponsors: Bristlecone Health, Inc.; University of Minnesota - Clinical and Translational Science Institute
Recruiting - Conditions: Alzheimer Dementia; Caregiver; Dementia Alzheimers
Intervention: Behavioral: Telephone-delivered Mindfulness
Sponsors: University of North Carolina, Chapel Hill; National Institute on Aging (NIA)
Not yet recruiting - PhysIcal Exercise ,Cerebral, COgnitive and Metabolome in People at Risk of Mild Cognitive ImpairmentConditions: Mild Cognitive Impairment; Alzheimer Dementia
Intervention: Behavioral: Supervised Exercise Programme
Sponsors: University of Cadiz; Centro de Excelencia en Metabolómica y Bioanálisis (CEMBIO); Servicio Central de Neuroimagen de la Universidad Pablo de Olavide; Consejería de Salud y Bienestar Social, Andalucía
Recruiting - Conditions: Subjective Cognitive Decline; Preclinical Alzheimer's Disease
Intervention: Diagnostic Test: Neuropsychological scale
Sponsor: XuanwuH 2
Recruiting - Conditions: Alzheimer Disease; Aging; MCI
Intervention: Device: TMS
Sponsors: Duke University; National Institute on Aging (NIA); National Institutes of Health (NIH)
Recruiting - Conditions: Alzheimer Disease; Dementia; Cognitive Decline; Cognitive Impairment; Dementia, Alzheimer Type
Interventions: Behavioral: Social Dancing; Behavioral: Treadmill Walking
Sponsors: Albert Einstein College of Medicine; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment; Cognitive Decline
Interventions: Radiation: Amyloid PET scan; Drug: Tau PET scan using MK-6240; Behavioral: Neurocognitive testing; Other: MRI
Sponsors: University of California, Irvine; National Institute on Aging (NIA)
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease; Dementia
Intervention: Drug: Flutemetamol (Vizamyl)
Sponsor: University of Zurich
Recruiting - Conditions: Alzheimer's Disease; Obesity; Diabetes Mellitus
Interventions: Dietary Supplement: Boost A; Behavioral: Healthy Living Diet
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: Primary Progressive Aphasia With Suspected Alzheimer's Disease
Interventions: Drug: 18F-AV-1451; Device: PET
Sponsors: Northwestern University; National Institute on Aging (NIA)
Recruiting - Condition: Dementia; Alzheimer, Mixed Type (Etiology)
Intervention: Device: Transcranial Direct Current Stimulation
Sponsor: Centre for Addiction and Mental Health
Recruiting - Conditions: Amyloid Cerebral Angiopathy; Alzheimer Disease
Interventions: Device: Pet scan with FBB; Device: MRI scan; Biological: APO E genotyping
Sponsor: Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - Conditions: Traumatic Brain Injury; Dementia Alzheimers
Interventions: Device: MindPod Dolphin; Device: Hand Bike
Sponsors: Johns Hopkins University; United States Department of Defense
Not yet recruiting - Condition: Dementia
Intervention: Behavioral: IN-PEACE Dementia Care Coordination
Sponsors: Indiana University; Regenstrief Institute, Inc.
Recruiting - Conditions: Delirium; Dementia
Intervention: Other: PREPARED Trial Intervention
Sponsor: McGill University
Recruiting - Conditions: Traumatic Brain Injury; Dementia; Alzheimer Disease
Intervention: Other: traumatic brain injury
Sponsors: Taipei Medical University Shuang Ho Hospital; Chang Gung Memorial Hospital
Recruiting - Conditions: Traumatic Brain Injury; Post Traumatic Stress Disorder; Alzheimer's Disease; Mild Cognitive Impairment
Intervention:
Sponsors: University of Southern California; United States Department of Defense; Telemedicine & Advanced Technology Research Center; Northern California Institute of Research and Education; San Francisco Veterans Affairs Medical Center; Alzheimer's Therapeutic Research Institute
Recruiting - Conditions: Alzheimer Disease; Nutritional Intervention; Cognitive Function
Interventions: Dietary Supplement: EGCG; Dietary Supplement: Placebo EGCG; Other: Personalized intervention; Other: Lifestyle recommendations
Sponsors: Parc de Salut Mar; Fundacion IMIM; Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Not yet recruiting - Condition: Family Caregiver
Intervention: Other: Circle Dance Program (CircleCare)
Sponsors: Universidade Federal de Sao Carlos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Universidade Estadual Paulista Júlio de Mesquita Filho
Recruiting - Condition: Dementia; Alzheimer, Mixed Type (Etiology)
Interventions: Dietary Supplement: Omni-Biotic Stress Repair; Dietary Supplement: placebo
Sponsor: Medical University of Graz
Recruiting - Conditions: Living Alone; Alzheimer Disease; Mild Cognitive Impairment
Intervention:
Sponsor: University of California, San Francisco
Recruiting - Conditions: Alzheimer Disease; Dementia; Mild Cognitive Impairment
Interventions: Device: Optical Coherence Tomography Angiography (OCTA) Imaging; Device: Noninvasive Retinal Amyloid Imaging (NRAI)
Sponsor: Oregon Health and Science University
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention: Drug: grape seed polyphenolic extract, resveratrol
Sponsors: Johns Hopkins University; Icahn School of Medicine at Mount Sinai
Recruiting - Conditions: Healthy; Mild Cognitive Impairment; Alzheimer Disease
Interventions: Device: real anodal transcranial direct current stimulation (tDCS); Device: sham transcranial direct current stimulation (tDCS)
Sponsor: University of Bern
Recruiting - Conditions: Traumatic Brain Injury; Alzheimer Disease; Veterans; Family Caregivers; Caregiver Burden; Quality of Life
Interventions: Other: ABC ANSWERS; Other: Control
Sponsors: Indiana University; Richard L. Roudebush VA Medical Center; Cleveland State University
Recruiting - Conditions: Dementia; Alzheimer Disease; Memory Loss
Intervention: Behavioral: psychoeducational skills training intervention
Sponsor: Arizona State University
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Age-Related Memory Disorders; Dementia
Interventions: Behavioral: Salient Cues; Behavioral: Spaced Retrieval Education
Sponsors: Grand Valley State University; Michigan State University
Recruiting - Conditions: Mild Cognitive Impairment; Dementia; Alzheimer's Disease
Intervention: Drug: [18F]Flutemetamol
Sponsor: University of Utah
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Frontotemporal Dementia
Interventions: Device: Spectral-Domain Optical Coherence Tomography (SD-OCT); Device: Magnetic Resonance Imaging (MRI); Device: Positron Emission Tomography (PET); Diagnostic Test: Comprehensive Ophthalmic Examination; Device: Fundus Photography
Sponsor: University of Michigan
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Progressive Supranuclear Palsy
Intervention: Drug: Radiopharmaceuticals
Sponsors: University of California, Berkeley; University of California, San Francisco
Recruiting - Conditions: Dementia; Alzheimer Disease; Vascular Dementia
Intervention: Other: Exercise
Sponsors: Universidade do Porto; Fundação para a Ciência e a Tecnologia
Recruiting - Conditions: Dementia; Alzheimer Disease; Memory Loss
Interventions: Behavioral: Care to Plan; Behavioral: Usual Care
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - Conditions: Alzheimer's Disease; Traumatic Brain Injury; Depression
Intervention: Drug: 18F-AV-1451
Sponsor: Avid Radiopharmaceuticals
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease; Healthy
Interventions: Device: DVA; Device: FDOCT; Device: Pattern ERG; Device: Optical Coherence Tomography
Sponsor: Medical University of Vienna
Recruiting - Conditions: Diabetes; Dementia; Alzheimer Disease
Interventions: Behavioral: EQUIPED-ADRD Intervention; Behavioral: Control (CON)
Sponsors: NYU Langone Health; National Institutes of Health (NIH)
Recruiting - Conditions: Delirium; Dementia Alzheimers; Respiratory Failure
Intervention:
Sponsor: Wake Forest University Health Sciences
Recruiting - Conditions: Memory Complaint; Alzheimer Disease; Phosphorylated Metabolism Profile; Magnetic Resonance Spectroscopy
Intervention: Other: Additional sequence performed during MRI scan
Sponsor: Poitiers University Hospital
Recruiting - Conditions: Alzheimer Disease; Gastric Cancer; Urologic Cancer; Pneumological Cancer
Intervention: Device: olfactory measuring device
Sponsors: Nouvelle Clinique Bonnefon; University Hospital, Montpellier
Not yet recruiting - Conditions: Alzheimer Disease; Gastric Cancer; Urologic Cancer; Pneumological Cancer
Intervention: Device: olfactory measuring device
Sponsor: University Hospital, Montpellier
Not yet recruiting - Conditions: Alzheimer Disease; Schizophrenia; Major Depressive Disorders
Intervention:
Sponsors: Tianjin Medical University General Hospital; Tianjin Medical University Cancer Institute and Hospital; Tianjin Medical University Second Hospital; Tianjin First Central Hospital; Pingjin Hospital,Logistics University of Chinese People's Armed Police Forces; School of Medical Imaging, Tianjin Medical University; Tianjin Huanhu Hospital; Beijing Hospital; Chinese PLA General Hospital; Beijing Tongren Hospital; Xuanwu Hospital, Beijing; Peking Union Medical College Hospital; Beijing Normal University; Chinese Academy of Science Institute of Automation; The Second Hospital of Hebei Medical University; The First Affiliated Hospital of Shanxi Medical University; Inner Mongolia Medical College Hospital; First Hospital of Jilin University; The Frist Hospital Of China Medical University; The First Affiliated Hospital of Dalian Medical University; RenJi Hospital; Huashan Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School; Nanjing PLA General Hospital; The First Affiliated Hospital with Nanjing Medical University; Xuzhou Medical University; Second Affiliated Hospital, School of Medicine, Zhejiang University; First Affiliated Hospital of Wenzhou Medical University; The First Affiliated Hospital of Anhui Medical University; Shan dong Medical Imaging Research Institute; Qilu Hospital of Shandong University; Yantai Yuhuangding Hospital; Henan Provincial Hospital; The First Affiliated Hospital of Zhengzhou University; Tongji Hospital; Wuhan University; Xiangya Hospital of Central South University; Central South University; Guangdong General Hospital; The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine; South China Normal University、Hainan General Hospital; First Affiliated Hospital Xi'an Jiaotong University; Xijing Hospital; Tang-Du Hospital; LanZhou University; West China Hospital; Second Affiliated Hospital of Wenzhou Medical University; University of Electronic Science and Technology of China; First Affiliated Hospital of Chongqing Medical University; Southwest Hospital, China; The University of Science and Technology of China; Guangdong No.2 Provincial People's Hospital
Recruiting - Conditions: Early Onset Alzheimer Disease; Mild Cognitive Impairment; Depression; Aging
Intervention:
Sponsor: ElMindA Ltd
Recruiting - Conditions: Gut Microbiota; Mild Cognitive Impairment; Dementia, Alzheimer Type; Neuroimaging
Interventions: Dietary Supplement: Probiotic supplemented intervention; Dietary Supplement: Functional foods; Dietary Supplement: Placebo
Sponsors: XuanwuH 2; First Hospital of Tsinghua University; Beijing Normal University
Recruiting - Conditions: Alzheimer Disease (AD); Frontotemporal Lobar Degeneration; Dementia With Lewy Bodies (DLB); Parkinson Disease Dementia (PDD); Progressive Supranuclear Palsy (PSP); Corticobasal Degeneration (CBD)
Intervention:
Sponsors: Amoneta Diagnostics SAS; European Commission; Firalis SA; University Hospital, Strasbourg; Centre Hospitalier Universitaire Vaudois; IRCCS Centro San Giovanni di Dio Fatebenefratelli; Hôpitaux Civils de Colmar; Istanbul University; Assistance Publique - Hôpitaux de Paris; University Hospital, Lille; University Hospital, Geneva; Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Erasme University Hospital; University Hospital, Montpellier; Centre Hospitalier Universitaire de Besancon; Centre Hospitalier Universitaire de Nice
Recruiting - Conditions: Alzheimer's Disease (Incl Subtypes); Dementia; Mild Cognitive Impairment
Interventions: Behavioral: Dance Group; Behavioral: Non-Group Dance; Behavioral: Social Group; Behavioral: No Contact
Sponsors: Wake Forest University Health Sciences; National Center for Complementary and Integrative Health (NCCIH)
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment; Mild Cognitive Impairment; Dementia Alzheimers; Dementia, Mild; Dementia, Alzheimer Type; Dementia of Alzheimer Type; Dementia; Cognitive Impairment, Mild; Cognitive Decline
Interventions: Device: GammaSense Stimulation System (Active Settings); Device: GammaSense Stimulation System (Sham Settings)
Sponsor: Cognito Therapeutics, Inc.
Recruiting - Conditions: Major Depressive Disorder; Alzheimer Disease; Mild Cognitive Impairment
Intervention: Device: Brainsway H1-Coil Deep TMS System
Sponsors: Rotman Research Institute at Baycrest; Brainsway; Centre for Addiction and Mental Health
Recruiting - Conditions: Dementia; Alzheimer's Disease; Frontotemporal Dementia
Interventions: Device: In-home technology; Device: Limited in-home technology
Sponsors: University of California, Berkeley; University of California, San Francisco; People Power Company; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; Dementia, Mixed; Dementia; Behavior Problem; Dementia, Alzheimer Type
Intervention: Device: Transcranial Direct Current Stimulation (tDCS)
Sponsors: Centre for Addiction and Mental Health; BrightFocus Foundation
Recruiting - Conditions: Dementia, Vascular; Alzheimer Dementia; Lewy Body Dementia With Behavioral Disturbance
Interventions: Device: Activlink insole; Other: Activlink Phone Application
Sponsors: University of Florida; National Institute on Aging (NIA); Aster Labs, Inc
Not yet recruiting - Conditions: Alzheimer Disease; Dementia; Mild Cognitive Impairment; Subjective Cognitive Decline
Intervention: Procedure: Preventive strategies advice and dementia risk estimate disclosure
Sponsor: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Recruiting - Conditions: Dementia Alzheimers; Dementia; Dementia, Vascular; Dementia Senile
Intervention:
Sponsor: Moorfields Eye Hospital NHS Foundation Trust
Not yet recruiting - Conditions: Cerebral Amyloid Angiopathy; Intracranial Hemorrhages; Alzheimer Disease
Intervention: Drug: 1. amyloid PET；2. T807 PET
Sponsor: National Taiwan University Hospital
Recruiting - Conditions: Major Depression; Alzheimer's Disease; Alcoholism; Schizophrenia
Intervention:
Sponsor: Charite University, Berlin, Germany
Recruiting - Conditions: Dementia; Alzheimer Disease; Mild Cognitive Impairment; Aging; Cognitive Impairment
Intervention: Behavioral: Cognitive Training
Sponsors: University of Leicester; The Dunhill Medical Trust; University Hospitals, Leicester; Leicestershire Partnership Trust; University of Nottingham; Lumosity
Recruiting - Conditions: Aphasia, Primary Progressive; Anomia; Alzheimer Disease
Interventions: Behavioral: Phonological; Behavioral: Orthographic; Behavioral: Semantic; Behavioral: Lexical; Behavioral: Untrained
Sponsors: Georgetown University; National Institute on Deafness and Other Communication Disorders (NIDCD); National Institute on Aging (NIA); Johns Hopkins University
Recruiting - Condition: Dementia
Interventions: Drug: Mirtazapine; Other: Placebo
Sponsors: University of Sussex; Norwich Clinical Trials Unit; University of East Anglia; University of Cambridge; University College, London; London School of Economics and Political Science; University of Manchester; University of Newcastle Upon-Tyne; Birmingham and Solihull Mental Health NHS Foundation Trust; Alzheimer's Society; The Centre for Dementia Studies, Brighton and Sussex Medical School and SPFT
Recruiting - Condition: Caregivers
Interventions: Behavioral: LEAF Positive Emotion Intervention; Other: Emotion Reporting Control Condition
Sponsors: Northwestern University; University of California, San Francisco
Not yet recruiting - Conditions: Alzheimer Disease; Dementia; Mild Cognitive Impairment; Aging; Aging Disorder
Intervention:
Sponsor: Georgetown University
Recruiting - Conditions: Alzheimer's Disease; Dementia; Dementia, Vascular; Caregivers; Veterans
Interventions: Behavioral: Counseling (C); Behavioral: Care Consultation (CC)
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Healthy Volunteer; Alzheimer Disease; Frontotemporal Dementia; Parkinson Disease
Intervention: Drug: [18F]PI-2620
Sponsors: Asan Medical Center; Korea Health Industry Development Institute
Recruiting - Conditions: Dementia; Dementia Alzheimers; Frontotemporal Dementia; Pick's Disease With Dementia
Interventions: Device: MRI Brain Imaging; Behavioral: Mental Health Assessment and Computerized Cognitive Test
Sponsor: Washington University School of Medicine
Recruiting - Conditions: Alzheimer Disease, Early Onset; Alzheimer Disease; Alzheimer Dementia; Mild Cognitive Impairment; Memory Disorders; Memory Loss; Memory Impairment; Memory Disorders, Age Related; Alzheimer Disease, Late Onset; Cognitive Impairment; Dementia, Mild; Dementia, Alzheimer Type; Cognitive Decline
Intervention: Device: GammaSense Stimulation System (non-invasive, non-significant risk)
Sponsor: Cognito Therapeutics, Inc.
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Lithium Carbonate; Drug: Placebo oral capsule
Sponsors: Ariel Gildengers; National Institute on Aging (NIA)
Recruiting - Conditions: Multiple Sclerosis; Parkinson Disease; Amyotrophic Lateral Sclerosis; Alzheimer Disease
Intervention: Procedure: lumbar puncture
Sponsors: Neuromed IRCCS; IRCCS Multimedica
Recruiting - Conditions: Cognitive Impairment, Mild; Cognitive Dysfunction; Amyloid Plaque; Neurodegeneration; Inflammation, Brain
Interventions: Drug: Lenalidomide 10 mg; Drug: Placebos
Sponsors: The Cleveland Clinic; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Primary Progressive Aphasia; Mild Cognitive Impairment; Frontotemporal Dementia; Alzheimer Disease
Interventions: Device: Anodal tDCS + vSTM therapy; Device: Sham + short-term memory therapy
Sponsors: Johns Hopkins University; National Institutes of Health (NIH); National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Vascular Cognitive Impairment; Parkinson's Disease; Lewy Body Disease
Intervention: Other: Pittsburgh Compound B [11C]-PIB
Sponsors: Sunnybrook Health Sciences Centre; Brain Canada; Weston Brain Institute; GE Healthcare; University Health Network, Toronto; Centre for Addiction and Mental Health; Baycrest; St. Michael's Hospital, Toronto; Kensington Eye Institute
Recruiting - Condition: Dementia
Interventions: Other: Health System-based Dementia Care; Other: Community-based Dementia Care; Other: Enhanced Usual Care
Sponsors: University of California, Los Angeles; Patient-Centered Outcomes Research Institute; National Institute on Aging (NIA); Yale University; Benjamin Rose Institute on Aging; Baylor Scott and White Health; Wake Forest University Health Sciences; University of Texas; Geisinger Clinic; University of Oklahoma; RAND
Recruiting - Conditions: Diet Modification; Cognitive Decline; Cognitive Change
Interventions: Other: Multicultural Healthy Diet; Other: Usual Diet plus Self-Care
Sponsors: Albert Einstein College of Medicine; Penn State University; University of Pennsylvania; University of Minnesota - Clinical and Translational Science Institute; National Institute on Aging (NIA)
Recruiting - Condition: Depression
Interventions: Behavioral: Guided Imagery and Mindfulness; Behavioral: Facilitated Discussion
Sponsors: Massachusetts General Hospital; National Institute on Aging (NIA)
Recruiting - Conditions: Dementia; Parkinson; Altered Behavior in Alzheimer Disease; Demyelinating Autoimmune Diseases, CNS; Demyelinating Sensorimotor Neuropathy; Corticobasal Degeneration
Interventions: Procedure: Microcannula Harvest Adipose; Device: Centricyte 1000; Procedure: Sterile Normal Saline Infusion
Sponsors: Regeneris Medical; Global Alliance for Regenerative Medicine; Robert W. Alexander, MD, FICS; Regeneris Medical Inc
Not yet recruiting - Conditions: Alzheimer Disease and Related Dementias; Inherited Neurodegenerative Disorders; Inherited Metabolic Disorders (Inborn Errors of Metabolism); Undiagnosed Diseases; Healthy Volunteer
Intervention:
Sponsor: National Human Genome Research Institute (NHGRI)
Recruiting - Conditions: Mild Cognitive Impairment; Cognitive Decline; Healthy Aging
Interventions: Dietary Supplement: melatonin; Other: placebo
Sponsor: Nazan Aksan
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Radiation: [C-11]; Drug: Pittsburgh Compound B
Sponsors: University of Pittsburgh; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Subjective Cognitive Concerns (SCC)
Intervention: Behavioral: Intervention
Sponsor: University of California, Davis
Recruiting - Condition: Dementia Caregiving
Intervention: Behavioral: Wish Outcome Obstacle Plan
Sponsors: Yale University; National Institute on Aging (NIA)
Recruiting - Condition: Health Communication
Intervention: Behavioral: Me & My Wishes
Sponsors: University of Utah; Brown University; National Institute on Aging (NIA)
Recruiting - Conditions: Dementia; Staff Attitude
Intervention: Behavioral: Speeko for Elderspeak
Sponsors: University of Kansas Medical Center; National Institute on Aging (NIA)
Not yet recruiting - Condition: Memory Disorders
Intervention: Other: no intervention
Sponsor: Hospices Civils de Lyon
Not yet recruiting - Conditions: Dementia; Traumatic Brain Injury
Intervention: Behavioral: Caregiver Coaching
Sponsor: University of Alabama at Birmingham
Recruiting - Condition: Sleep
Intervention: Behavioral: Sleep
Sponsor: University of Massachusetts, Amherst
Recruiting - Condition: Behavioral Symptoms
Interventions: Other: Approach based on the meanings of vocal behaviours; Other: Usual practices
Sponsor: Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Cognitive Change; Energy Metabolism; Sleep Disturbance
Intervention: Device: MyTAP oral appliance plus mouth shield
Sponsors: The University of Texas at Dallas; Texas A & M University Baylor College Of Dentistry; University of Texas, Southwestern Medical Center at Dallas
Recruiting - Conditions: Mild Cognitive Impairment; Major Depressive Disorder; Alzheimer's Dementia; Transcranial Direct Current Stimulation; tDCS
Interventions: Other: Receive tDCS+CR; Other: Facilitate tDCS + CR
Sponsors: Centre for Addiction and Mental Health; CAMH Foundation
Recruiting - Condition: Dementia
Interventions: Behavioral: PLAN; Behavioral: Standard of Care
Sponsors: Johns Hopkins University; National Institutes of Health (NIH)
Not yet recruiting - Conditions: Dementia; Alzheimer Disease; Circadian Rhythm Disorders; Circadian Rhythm Sleep Disorder; Insomnia; Hypersomnia; Cognitive Impairment; Cognitive Decline; Mild Cognitive Impairment; Frontotemporal Dementia; Neurocognitive Disorders; Vascular Dementia; Sleep Disorder; Memory Impairment
Interventions: Behavioral: Attention-Control Condition; Behavioral: Timed Activity Intervention
Sponsor: University of Pennsylvania
Recruiting - Conditions: Psychosis; Dementia; Aggression; Agitation; Alzheimer Dementia
Interventions: Drug: MP-101; Drug: Placebo
Sponsor: Mediti Pharma Inc.
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease; Frontal Dementia; Huntington Disease; Traumatic Brain Injury; Stroke
Intervention: Behavioral: social cognition
Sponsor: Centre Hospitalier Universitaire, Amiens
Recruiting - Conditions: Dementia; Dementia, Vascular; Dementia With Lewy Bodies; Dementia, Mixed; Dementia Alzheimers; Behavioural and Psychiatric Symptoms of Dementia; Depression; Quality of Life
Interventions: Other: Music Intervention; Other: Reading Intervention
Sponsors: Anglia Ruskin University; University of Melbourne; Norwegian Academy of Music; University of Applied Sciences Würzburg-Schweinfurt; University School of Physical Education, Krakow, Poland; Alzheimer's Society; Methodist Homes for the Aged; Saffron Hall Trust; Cambridgeshire and Peterborough NHS Foundation Trust
Not yet recruiting - Conditions: Stroke, Ischemic; Stroke Syndrome; Stroke; Stroke, Acute; Dementia; Brain Ischemia; Brain Diseases; Alzheimer Disease; Health Attitude; Health Knowledge, Attitudes, Practice; Health Personnel Attitude; Healthy Aging
Intervention: Behavioral: Neuro-QoL questionnaire
Sponsor: Chinese University of Hong Kong
Recruiting - Conditions: Gait Apraxia; Mild Cognitive Impairment; Subjective Cognitive Impairment; Cerebral Atrophy; Alzheimer Disease; Dementia
Intervention:
Sponsor: Lawson Health Research Institute
Recruiting - Conditions: Dementia; Caregiver Burnout; Carer Stress Syndrome; Relatives; Partner, Domestic
Intervention: Other: Care Management
Sponsors: German Center for Neurodegenerative Diseases (DZNE); Gemeinsamer Bundesausschuss (GBA); University Medicine Greifswald
Not yet recruiting - Conditions: Dementia; Delirium Superimposed on Dementia
Intervention: Other: VR-therapy
Sponsors: University Health Network, Toronto; Centre for Aging and Brain Health Innovation; Michael Garron Hospital
Not yet recruiting - Conditions: Healthy Individuals; Diabetes; Hypertension; Fabry Disease; Metabolic Disease; Alzheimer Disease; Dementia; Limbal Insufficiency; Phlyctenulosis; Ocular Rosacea; Graft Versus Host Disease in Eye; Dry Eye Syndrome
Intervention:
Sponsor: National Taiwan University Hospital
Not yet recruiting - Condition: Mild Cognitive Impairment
Interventions: Behavioral: ACT; Behavioral: Cycling Only; Behavioral: Cognitive Training Only; Behavioral: Stretching and Mental Stimulating Activities
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Rochester; Mayo Clinic; University of St Thomas
Recruiting - Conditions: Orthopedic Disorder; Neurologic Disorder; Urologic Diseases; Erectile Dysfunction; Autoimmune Diseases; Renal Failure; Renal Insufficiency; Kidney Diseases; Cardiac Event; Cardiomyopathies; CHF; Pulmonary Disease; COPD; Alzheimer Disease; Stroke; Neuropathy;Peripheral; Arthritis
Intervention: Biological: Amniotic and Umbilical Cord Tissue Procedure
Sponsor: R3 Stem Cell
Not yet recruiting - Conditions: Mild Cognitive Impairment (MCI); Alzheimer Disease (AD); Dementia With Lewy Bodies (DLB); Frontotemporal Lobar Degeneration (FTLD); Parkinsons Disease With Dementia (PDD); Transient Epileptic Amnesia (TEA); Temporal Lobe Epilepsy (TLE); Spinocerebellar Ataxias (SCA); HIV Associated Neurocognitive Disorder (HAND); Amyotrophic Lateral Sclerosis (ALS); Primary Lateral Sclerosis (PLS)
Intervention: Other: Neuraceq
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - Conditions: Coronary Heart Disease; Anemia; Bronchial Asthma; Stroke; Epilepsy; Parkinson's Disease; Heart Rhythm Disorders; Alzheimer's Disease; Neuromuscular Diseases; Diabetes; Chronic Heart Failure; Chronic Obstructive Pulmonary Disease; Chronic Kidney Diseases
Intervention:
Sponsors: Russian Federation of Anesthesiologists and Reanimatologists; Kuban State Medical University
Recruiting - Conditions: Ataxia; Dystonia; Parkinson's Disease; Amyotrophic Lateral Sclerosis; Corticobasal Degeneration; Multiple System Atrophy; Alzheimer's Disease; Lewy Body Dementia; Parkinson Disease-Dementia; Dentatorubral-pallidoluysian Atrophy; Creutzfeldt-Jakob Disease and Fatal Familial Insomnia; Fragile X-associated Tremor/Ataxia Syndrome; Krabbe's Disease; Niemann-Pick Disease, Type C; Neuronal Ceroid Lipofuscinosis
Intervention:
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: Advance Care Planning
Intervention: Other: Advance Care Planning
Sponsors: University of Florida; Florida Department of Health
Recruiting - Condition: Mild Cognitive Impairment
Intervention:
Sponsors: NYU Langone Health; NeuroTrack Technologies, Inc.
Recruiting - Conditions: Delirium; Cognitive Impairment; Alzheimer; Early Onset; Trauma; Polytrauma; Traumatic Brain Injury; ICU; Critical Illness
Intervention: Other: Non-interventional observational prospective cohort study
Sponsors: Vanderbilt University Medical Center; National Institutes of Health (NIH); National Institute of General Medical Sciences (NIGMS)
Recruiting - Condition: Lewy Body Dementia
Interventions: Drug: LY3154207; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Biological: Elderberry Juice; Other: Placebo
Sponsor: University of Missouri-Columbia
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Behavioral: Planning for the Future; Behavioral: Enhanced Medical Engagement; Behavioral: Confidence Building and Social Engagement; Behavioral: Physical Intervention; Behavioral: Medical Adherence
Sponsor: Allison Gibson
Not yet recruiting - Condition: Healthy Older Adults Ages 65-89
Intervention:
Sponsors: University of Colorado, Denver; National Institute on Aging (NIA)
Recruiting - Condition: Dementia
Interventions: Behavioral: SPIRIT-in person; Behavioral: SPIRIT-remote; Behavioral: Usual care
Sponsors: Emory University; National Institute on Aging (NIA)
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Nicotine Transdermal Patch; Drug: Placebo Patch
Sponsors: University of Southern California; National Institute on Aging (NIA); Vanderbilt University; Alzheimer's Therapeutic Research Institute
Recruiting - Condition: Dementia
Interventions: Drug: Cholinesterase inhibitor; Drug: Sham discontinuation
Sponsor: VA Office of Research and Development
Recruiting - Condition: Insomnia
Interventions: Behavioral: Cognitive Behavioral Therapy for Insomnia (CBT-I); Behavioral: Active Control
Sponsors: University of Kansas Medical Center; National Institute on Aging (NIA); National Institutes of Health (NIH)
Recruiting - Conditions: Aging; Cognitive; Ketones; Blood Sugar
Intervention: Drug: Jardiance 25 mg
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Device: Transcutaneous vagal nerve stimulation; Device: Sham stimulation
Sponsors: University of Florida; Department of Health and Human Services; National Institute on Aging (NIA)
Recruiting - Conditions: Anticholinergics; Cognitive Function
Intervention:
Sponsors: Region Skane; Angelholm Hospital
Recruiting - Condition: Caregiver Burden
Intervention: Behavioral: Options Counselor Health Educator (OC-HE) Intervention
Sponsors: Sato Ashida; National Institute on Aging (NIA); University of Kansas School of Nursing; University of Michigan; Boston College; Drexel University Dornsife School of Public Health
Not yet recruiting - Condition: Dementia
Interventions: Other: Foods consistent with a MDP; Other: Physical Activity; Other: Control
Sponsor: University of East Anglia
Recruiting - Conditions: Cerebrovascular Disorders; Dementia
Intervention:
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Conditions: Alteration of Cognitive Function; Hypoxia
Intervention: Other: 2-hour period of hypoxia
Sponsor: University Hospital, Lille
Recruiting - Condition: Primary Progressive Aphasia
Intervention: Behavioral: Evidence-Based Treatment
Sponsors: Northwestern University; National Institute on Aging (NIA)
Recruiting - Condition: Cognitive Change
Interventions: Behavioral: High-Demand Photography; Behavioral: Moderate-Demand Photography; Behavioral: At-Home Engagement
Sponsors: The University of Texas at Dallas; University of Texas Southwestern Medical Center; Southern Methodist University; National Institute on Aging (NIA)
Recruiting - Condition: Dementia
Intervention:
Sponsors: University of Eastern Finland; National Institute for Health and Welfare, Finland; Kuopio University Hospital
Recruiting - Conditions: Healthy; Neurodegenerative Disease
Intervention:
Sponsor: University of California, San Francisco
Recruiting - Condition: Memory Impairment
Interventions: Device: real anodal tDCS healthy elderly; Device: real tACS healthy elderly; Device: sham tES healthy elderly; Device: real anodal tDCS MCI; Device: real tACS MCI; Device: sham tES MCI; Device: real anodal tDCS AD; Device: real tACS AD; Device: sham tES AD
Sponsor: University of Bern
Recruiting - Condition: Dementia-related Psychosis
Interventions: Drug: Placebo; Drug: Pimavanserin 34 mg; Drug: Pimavanserin 20 mg
Sponsor: ACADIA Pharmaceuticals Inc.
Recruiting - Condition: Neurodegenerative Disorders
Intervention:
Sponsor: Hadassah Medical Organization
Recruiting - Conditions: Down Syndrome; Mild Cognitive Impairment
Interventions: Drug: Low Dose Nicotine (7mg); Drug: Moderate Dose Nicotine (14mg)
Sponsor: Vanderbilt University Medical Center
Recruiting
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