 |
- Conditions: Alcohol Use Disorder; Sexually Transmitted Diseases
Interventions: Drug: Standardized kudzu; Other: Placebo
Sponsors: University of California, San Francisco; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: N-acetylcysteine; Drug: Placebo oral capsule
Sponsor: Medical University of South Carolina
Not yet recruiting - Condition: Alcohol Use Disorder
Intervention: Behavioral: DynamiCare Rewards
Sponsors: DynamiCare Health; Johns Hopkins University
Not yet recruiting - Conditions: Alcohol Abuse; Alcohol Use Disorder; Alcohol Drinking; Alcohol Dependence; Alcohol; Harmful Use
Interventions: Behavioral: Telecoach; Behavioral: TeleCoach control
Sponsor: Karolinska Institutet
Not yet recruiting - Conditions: Alcohol-Related Disorders; Alcohol Use Disorders; Alcohol Drinking; Alcoholism; Alcohol Abuse
Interventions: Behavioral: Drink Tracking (MA); Behavioral: Adaptive Tailored (TA); Behavioral: Tailored (TO)
Sponsors: Partnership for Drug-Free Kids; Feinstein Institute for Medical Research
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Other: MCII; Other: Treatment as usual
Sponsors: Susanne Rösner; University of Konstanz; Zurich University of Applied Sciences; New York University; University of Hamburg
Recruiting - Conditions: Cannabis; Cannabis Use; Marijuana; Marijuana Usage; Alcohol Drinking
Interventions: Drug: Marijuana; Drug: Alcohol
Sponsor: Shanna Babalonis, PhD
Not yet recruiting - Condition: Alcohol Drinking in College
Interventions: Behavioral: Mobile chat-based instant messages; Behavioral: Alcohol brief intervention
Sponsor: The University of Hong Kong
Not yet recruiting - Condition: Surgical Site Infections
Interventions: Drug: CHX disinfection; Drug: PI Disinfection
Sponsors: University Hospital, Basel, Switzerland; Swiss National Science Foundation
Recruiting - Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot TrialCondition: Alcohol Use Disorder
Intervention: Device: Deep Brain Stimulation
Sponsor: Sunnybrook Health Sciences Centre
Recruiting - Condition: Hepatitis C
Intervention: Procedure: Campaign days
Sponsors: Kirby Institute; National Health and Medical Research Council, Australia
Recruiting - Condition: Drinking, Alcohol
Interventions: Behavioral: Advice; Behavioral: Self-monitoring; Behavioral: Feedback
Sponsors: Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Condition: Post Traumatic Stress Disorder
Interventions: Drug: Topiramate; Other: Placebo
Sponsor: New York University School of Medicine
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Behavioral: Control; Behavioral: Functional Analysis; Behavioral: Cognitive Restructuring; Behavioral: Dealing With Cravings
Sponsors: University of Massachusetts, Worcester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Abuse
Interventions: Behavioral: Aversive cue; Behavioral: Neutral cue
Sponsors: Indiana University; Purdue University
Recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Exenatide; Other: Sham injection
Sponsors: Boston Medical Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Conditions: Post Traumatic Stress Disorder; Problem Drinking
Intervention: Behavioral: Web-based intervention
Sponsors: University of Washington; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Condition: Alcoholic Hepatitis
Intervention: Drug: GCSF
Sponsor: Postgraduate Institute of Medical Education and Research
Recruiting - Conditions: Intoxication Alcohol; Intoxication THC; Intoxication Combined Alcohol THC
Interventions: Drug: Dronabinol; Drug: Ethanol; Drug: Placebo Dronabinol; Drug: Placebo Ethanol
Sponsors: Massachusetts General Hospital; National Institute on Drug Abuse (NIDA)
Not yet recruiting - Conditions: Cannabis Use; Alcohol Use Disorder; Healthy
Intervention: Diagnostic Test: Visuomotor adaptation task
Sponsor: Hospital Clinic of Barcelona
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Oxytocin; Drug: Placebo
Sponsor: University of North Carolina, Chapel Hill
Not yet recruiting - Conditions: Depression; Substance Use Disorders
Interventions: Behavioral: Behavioural Activation; Behavioral: Treatment as Usual
Sponsors: University of Sheffield; University of North Carolina, Chapel Hill
Recruiting - Conditions: Healthy; Alcohol Drinking
Interventions: Drug: Zopiclone; Behavioral: hangover; Drug: Placebo oral capsule
Sponsors: Petri Vainio; University of Turku
Not yet recruiting - Condition: Substance Use
Intervention: Behavioral: Unidos Se Puede
Sponsors: Oklahoma State University; National Institute of General Medical Sciences (NIGMS)
Recruiting - Condition: Drunk Driving
Interventions: Behavioral: Contingency Management; Behavioral: Control
Sponsors: The University of Texas Health Science Center at San Antonio; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Cesarean Section; Infection; Surgical Site Infection
Interventions: Drug: Chlorhexidine-alcohol; Drug: Povidine-iodine; Drug: Sterile saline
Sponsor: Columbia University
Recruiting - Conditions: Alcohol Use Disorder; HIV/AIDS; Hepatitis C; Binge Drinking
Intervention: Behavioral: Intervention: (Clinician's Guide + HealthCall for HIV/HCV)
Sponsors: New York State Psychiatric Institute; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Conditions: Adolescent Problem Behavior; Truancy; Unsocialized; Marijuana Abuse; Truancy; Socialized; Substance Abuse; Alcohol Abuse
Interventions: Behavioral: Motivational + Family Check-up (MET+FCU); Other: Psychoeducation
Sponsor: Brown University
Not yet recruiting - Conditions: Insomnia; Alcohol; Harmful Use
Interventions: Behavioral: Cognitive Behavioral Therapy for Insomnia (CBT-I); Behavioral: Sleep Hygiene
Sponsor: University of Missouri-Columbia
Recruiting - Condition: Human Immunodeficiency Virus (HIV)
Interventions: Device: Skyn Monitor Lab Session 1; Device: Skyn Monitor Field Test with EMA App; Device: Skyn Monitor Lab Session 2
Sponsors: University of Florida; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Conditions: Mental Health; Risk Reduction Behavior; Primary Health Care
Interventions: Behavioral: Digital Health Profile; Behavioral: Treatment as usual
Sponsors: Karolinska Institutet; The Swedish Research Council
Recruiting - Conditions: Alcohol Drinking; Suicide, Attempted; Adolescent Behavior
Intervention: Behavioral: iASIST
Sponsor: Boston Children’s Hospital
Recruiting - Conditions: Risk of Alcohol-exposed Pregnancy; Risk of Tobacco-exposed Pregnancy; Risk of Marijuana-exposed Pregnancy
Interventions: Behavioral: Computer tablet-delivered C4H; Behavioral: Person-delivered C4H; Behavioral: Brief Advice
Sponsors: University of Texas at Austin; Baylor College of Medicine; The University of Texas Health Science Center, Houston; University of Houston
Recruiting - Condition: Underage Drinking
Intervention: Behavioral: eCHECKUP TO GO
Sponsors: Boise State University; National Institutes of Health (NIH); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Condition: Intoxication Alcohol
Intervention: Behavioral: S-STOP
Sponsors: RRF Field Services LLC; Pacific Institute for Research and Evaluation
Recruiting - Conditions: mSBIRT - Mobile Screening, Brief Intervention, Referral to Treatment; SBIRT-CTS - Screening, Brief Intervention, Referral to Treatment Conventional Training and Supervision Strategy
Intervention: Behavioral: Screening, Brief Intervention, Referral to Treatment
Sponsors: New York State Psychiatric Institute; Columbia University; University of Pennsylvania
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Ibudilast; Drug: Placebo oral capsule
Sponsors: University of California, Los Angeles; National Institute on Alcohol Abuse and Alcoholism (NIAAA); MediciNova
Recruiting - Condition: Alcoholism
Interventions: Drug: Acamprosate Calcium; Drug: Calcium Citrate; Drug: Placebo; Drug: Placebo lead in
Sponsor: Technische Universität Dresden
Not yet recruiting - Condition: Alcohol Abuse
Intervention: Behavioral: ABCT_Military
Sponsors: University of Massachusetts, Worcester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol; Harmful Use
Interventions: Behavioral: In-person sessions: ABCP_P; Behavioral: Video conference sessions: ABCP_T
Sponsors: University of Massachusetts, Worcester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Alcohol Use Disorder; Alcoholism; Prescription Drug Dependence; Opioid-use Disorder; Neurofeedback
Interventions: Device: fNIRs-based Neurofeedback; Device: Sham feedback
Sponsor: Milton S. Hershey Medical Center
Not yet recruiting - Condition: Alcohol Drinking
Interventions: Drug: Propanolol; Drug: Placebo
Sponsors: Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Conditions: Alcohol Withdrawal Delirium; Alcohol Withdrawal; Alcohol Withdrawal Seizures
Interventions: Drug: Phenobarbital Sodium; Drug: Inactive placebo
Sponsor: St. Michael's Hospital, Toronto
Not yet recruiting - Conditions: Overactive Bladder; Urinary Urgency; Urinary Bladder, Overactive; Urinary Incontinence, Urge; Caffeine; Alcohol Drinking; Lower Urinary Tract Symptoms
Interventions: Behavioral: Reducing Potentially Irritating Beverages; Behavioral: Adopting the USDA Healthy Eating Habits
Sponsors: University of Michigan; Blue Cross Blue Shield of Michigan Foundation; Arbor Research Collaborative for Health
Recruiting - Condition: Alcohol Use Disorder
Intervention: Device: Remote Monitoring with Ambulatory Detox
Sponsors: Stanford University; SoberLink, LLC
Not yet recruiting - Conditions: Alcohol Addiction; Alcohol Dependence
Intervention: Other: Qi Gong sessions
Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Alcohol; Drug: Placebos; Drug: Duloxetine; Drug: Methylphenidate
Sponsors: Craig Rush; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: PTSD; Depression; Chronic Pain; Alcohol Use Disorder; Traumatic Brain Injury
Interventions: Behavioral: Acceptance and Commitment Therapy to promote functional recovery in war veterans (ACT-FX); Behavioral: Treatment as usual (TAU)
Sponsor: VA Office of Research and Development
Not yet recruiting - Condition: Alcohol Drinking
Intervention: Other: Smart watch to measure Blood Alcohol Level
Sponsors: Boston Medical Center; KWJ Engineering
Not yet recruiting - Conditions: Endometrioma; Fertility Disorders
Interventions: Procedure: Surgery; Procedure: Sclerotherapy
Sponsor: Hospital Universitari de Bellvitge
Recruiting - Condition: Binge Drinking
Intervention: Other: Alcohol vs. Placebo
Sponsors: Michigan Technological University; University of Chicago; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Cannabis; Alcohol Drinking; Accident, Traffic
Interventions: Drug: THC 0; Drug: THC 125; Drug: THC 250; Other: BAC 0; Other: BAC .025; Other: BAC .049
Sponsors: Lakehead University; Ontario Ministry of Transportation
Not yet recruiting - Condition: Alcohol Consumption
Interventions: Other: NZ Step Away app; Other: Modified NZ Step Away app
Sponsors: University of Auckland, New Zealand; Waitemata District Health Board; University of Alaska Anchorage
Recruiting - Conditions: Alcohol Dependence; Alcohol Interaction
Interventions: Drug: PT150; Other: Beverage
Sponsors: Pop Test Oncology LLC; Pharmacotherapies for Alcohol and Substance Abuse Consortium; Congressionally Director Medical Research Programs; Michael Debakey Veterans Affairs Medical Center; Baylor College of Medical Center; University of California, San Diego
Recruiting - Condition: Healthy Participants
Interventions: Other: Road-tracking test; Other: Car-following test; Other: Harsh-braking test
Sponsors: Taisho Pharmaceutical Co., Ltd.; Nagoya University
Recruiting - Condition: Drinking, Alcohol
Interventions: Behavioral: Wisepill+SMS; Other: Wisepill-only
Sponsor: Butler Hospital
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Gemfibrozil 600 MG; Drug: Placebo oral capsule
Sponsor: The Mind Research Network
Recruiting - Conditions: Suicidal Ideation; Depression; Alcohol Abuse
Interventions: Drug: Intranasal ketamine; Drug: Placebo
Sponsor: The University of Texas Health Science Center, Houston
Recruiting - Condition: Drinking, Alcohol
Interventions: Behavioral: Alcohol Peer Mentor Intervention; Behavioral: Brief Advice
Sponsor: VA Office of Research and Development
Not yet recruiting - Conditions: Healthy Volunteers; Alcohol Drinking Related Problems; Alcohol-Related Disorders
Intervention:
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Use, Unspecified
Interventions: Behavioral: Feedback; Behavioral: Enhanced Usual Care
Sponsors: University of Pittsburgh; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Use Disorder
Interventions: Other: Cognitive training; Other: Control training
Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting - Condition: Alcohol Use Disorder
Intervention: Other: Intervention municipality
Sponsors: Maastricht University; Newcastle University; Technische Universität Dresden
Not yet recruiting - Condition: Fetal Alcohol Spectrum Disorders
Intervention: Behavioral: Tuning In to kids intervention
Sponsors: University of Rochester; National Institutes of Health (NIH)
Recruiting - Conditions: Alcohol Drinking; Weight Loss; Adiposity; Obesity; Visceral Obesity
Interventions: Other: Alcohol; Other: No Alcohol
Sponsors: Pennington Biomedical Research Center; Ursula A. White; Frank L. Greenway; Corby K. Martin
Recruiting - Conditions: Human Immunodeficiency Virus; Alcohol-Related Disorders; Drug Use
Intervention: Behavioral: Project Khanya
Sponsors: University of Maryland; University of Cape Town; National Institute on Drug Abuse (NIDA)
Recruiting - Condition: Heavy Drinking and Sexual Risk Behavior
Intervention: Behavioral: Brief intervention with text messaging to reduce sexual risk and heavy drinking among MSM
Sponsors: Boston University Charles River Campus; National Institutes of Health (NIH)
Recruiting - Condition: Drinking, Alcohol
Intervention: Behavioral: PFIcope+EMI
Sponsor: Butler Hospital
Not yet recruiting - Condition: Healthy Volunteers
Interventions: Dietary Supplement: Beer with 5.20 % alcohol; Dietary Supplement: Non-alcoholic beer with 0.45 % alcohol; Dietary Supplement: Non-alcoholic beer with 0.00 % alcohol
Sponsors: Universidade do Porto; Universidade Nova de Lisboa
Recruiting - Condition: Risk Behavior
Intervention: Behavioral: brief counseling
Sponsors: Hospital Universitario San Ignacio; Pontificia Universidad Javeriana
Recruiting - Condition: Tobacco Use Disorder
Interventions: Behavioral: CBT + EFT; Behavioral: CBT + EFT + CM
Sponsor: University of Oviedo
Recruiting - Condition: College Student Drinking
Interventions: Behavioral: college drinker's check up; Behavioral: Protective Behavioral Strategies Intervention; Behavioral: Ecological Momentary Intervention
Sponsors: James M. Henson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Dependence
Interventions: Behavioral: SHUTi; Other: insomnia education web-based program
Sponsor: National Institutes of Health Clinical Center (CC)
Not yet recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Ibudilast; Other: Placebo
Sponsor: University of California, Los Angeles
Recruiting - Conditions: Flushing; Alcohol-Related Disorders; Aldehyde Dehydrogenase Deficiency
Interventions: Drug: Brimonidine Tartrate; Drug: Placebo Vehicle Gel
Sponsor: University of California, San Francisco
Recruiting - Conditions: Cirrhosis; End Stage Liver Disease; Acute Kidney Injury; Liver Transplant; Complications; Chronic Kidney Diseases; Hepatitis c; Hepatitis B; NASH - Nonalcoholic Steatohepatitis; Alcoholic Cirrhosis; Hepatocellular Carcinoma
Interventions: Device: Esophageal cooling/warming device; Other: Mild hypothermia; Other: Normothermia
Sponsor: University of California, San Francisco
Recruiting - Condition: Alcohol Dependence
Interventions: Drug: Topiramate; Drug: Naltrexone
Sponsors: South West Sydney Local Health District; National Health and Medical Research Council, Australia; University of Sydney
Recruiting - Conditions: Schizophrenia; Bipolar Disorder; Major Depressive Disorder; Alcohol Dependence
Interventions: Behavioral: Usual CM; Behavioral: High-Magnitude CM; Behavioral: Shaping CM
Sponsors: Washington State University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Use Disorder
Interventions: Behavioral: Standard treatment (ST) PLUS web-based CBT4CBT; Behavioral: Standard Treatment (ST)
Sponsors: Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Conditions: Social Skills; Self-Criticism; Post-traumatic Stress Disorder; Depression; Alcohol Abuse; Drinking, College; Alcohol Drinking; Alcohol; Harmful Use; Social Stigma; Social Norms; Social Responsibility; Social Behavior; Empathy; Coping Skills; Coping Behavior
Intervention: Behavioral: Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
Sponsors: University of New Hampshire; University of Illinois at Chicago; University of South Florida; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Schizophrenia; Schizoaffective Disorder; Substance Use Disorders
Interventions: Drug: Brexpiprazole; Other: Treatment as Usual
Sponsors: University of Massachusetts, Worcester; Massachusetts General Hospital; University of North Carolina, Chapel Hill; Otsuka Pharmaceutical Co., Ltd.
Recruiting - Conditions: Sepsis Affecting Skin; Central Venous Catheter Related Bacteremia
Interventions: Drug: A (Chloraprep); Drug: B (Clorhexidine 2%)
Sponsor: Instituto de Investigacion Sanitaria La Fe
Not yet recruiting - Conditions: Alcohol Drinking; Alcohol Use Disorder; Alcohol Intoxication; Alcohol; Harmful Use; Alcoholism; Binge Drinking
Interventions: Drug: Alcohol; Other: Placebo
Sponsors: Carnegie Mellon University; National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Pittsburgh; Penn State University
Recruiting - Conditions: Alcoholic Cirrhosis; Alcoholic Liver Disease
Intervention:
Sponsors: University Hospital, Montpellier; University Hospital, Nīmes; Narbonne Hospital
Recruiting - Condition: Alcohol Use Disorder
Intervention: Behavioral: Brief intervention
Sponsors: New York State Psychiatric Institute; Northwell Health
Recruiting - Condition: Alcohol Use Disorder
Interventions: Radiation: [C-11]; Drug: NOP-1A
Sponsors: Rajesh Narendran; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Use Disorder
Interventions: Behavioral: Normative Feedback; Behavioral: Inhibitory Control Training; Behavioral: Working Memory Training
Sponsors: Craig Rush; National Institute on Drug Abuse (NIDA)
Recruiting - Conditions: Aspirin-Sensitive Asthma With Nasal Polyps; Samter's Syndrome
Interventions: Dietary Supplement: Water; Dietary Supplement: Red wine; Dietary Supplement: Polyphenolic Compounds
Sponsor: University of Virginia
Recruiting - Conditions: Marijuana Usage; Alcohol Drinking
Interventions: Drug: One day with a dose of placebo cannabis paired with alcohol; Drug: One day with a dose of active THC cannabis paired with alcohol
Sponsor: Hartford Hospital
Recruiting - Conditions: Alcohol Use Disorder; Social Anxiety Disorder
Interventions: Behavioral: Fully integrated treatment; Behavioral: Stand-alone Intensive Outpatient Program
Sponsors: University of California, Los Angeles; National Institute on Alcohol Abuse and Alcoholism (NIAAA); Matrix Institute on Addictions
Recruiting - Conditions: Opioid-Related Disorders; Alcohol-Related Disorders
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Not yet recruiting - Conditions: Depression; Problem Drinking
Interventions: Behavioral: MoodGYM; Behavioral: Check Your Drinking
Sponsor: Centre for Addiction and Mental Health
Recruiting - Condition: Alcohol Use Disorder
Intervention: Behavioral: Integrated Online CBT and MI
Sponsor: University of Manitoba
Recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Doxazosin XL; Drug: Placebo
Sponsor: The University of Texas Health Science Center, Houston
Not yet recruiting - Condition: Leiomyoma
Intervention: Device: Non-spherical polyvinyl alcohol particle or Tris-acryl gelatin microsphere
Sponsor: Severance Hospital
Recruiting - Condition: Alcoholic Hepatitis
Intervention: Drug: DUR-928
Sponsors: Durect; CTI Clinical Trial & Consulting Services
Recruiting - Conditions: Post Traumatic Stress Disorder; Alcohol Use Disorder
Interventions: Drug: Zonisamide; Drug: Placebo Comparator
Sponsors: Pharmacotherapies for Alcohol and Substance Abuse Consortium; Congressionally Directed Medical Research Programs; Michael Debakey Veterans Affairs Medical Center; Baylor College of Medicine
Not yet recruiting - Conditions: Alcohol Drinking; Sex Behavior; Men
Interventions: Drug: Alcohol; Other: Placebo (non-alcoholic beverage)
Sponsors: Syracuse University; National Institute on Alcohol Abuse and Alcoholism (NIAAA); Boston University; University of South Dakota
Recruiting - Conditions: Breast Cancer; Psychology, Social
Interventions: Behavioral: Motivational Intervention group; Behavioral: Educational advises group
Sponsors: Institut Bergonié; Ligue contre le cancer, France
Recruiting - Conditions: Alcohol Drinking; Chronic Inflammation; Neurocognitive Dysfunction; Liver Diseases; HIV Infections
Intervention: Behavioral: Contingency Management (CM)
Sponsors: University of Florida; University of Miami; Florida International University; Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Liver Diseases, Alcoholic
Intervention: Device: A-CHESS
Sponsors: New York Presbyterian Hospital; University of Wisconsin, Madison
Recruiting - Conditions: Alcohol Drinking; Violence
Interventions: Behavioral: Step 1 Treatment BI+HC; Behavioral: Step 1 Treatment BI+TM; Behavioral: Step 2 Treatment Responders; Behavioral: Step 2 Treatment Non-Responders
Sponsors: University of Michigan; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Alcohol Drinking; Alcohol Consumption, Youth
Interventions: Other: Personalized Feedback Intervention with Values; Other: Personalized Feedback Intervention Traditional
Sponsor: Oklahoma State University
Recruiting - Condition: Alcoholism
Intervention: Drug: Ibogaine Hydrochloride
Sponsors: University of Sao Paulo; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Conselho Nacional de Desenvolvimento Científico e Tecnológico
Not yet recruiting - Conditions: Diabetes; Endocrine System Diseases; Gastro-Intestinal Disorder; Neuro-Degenerative Disease; Epilepsy; Autoimmune Diseases; Renal Disease; Cardiac Disease; Metabolic Disease; Genetic Diseases, Inborn; Respiratory Disease; Hematologic Diseases; Autism Spectrum Disorder; Fetal Alcohol Spectrum Disorders; Traumatic Brain Injury; Stroke
Interventions: Other: Patient Navigator; Other: Usual Care
Sponsors: University of Calgary; Alberta Health Services; University of Alberta
Recruiting - Conditions: Alcohol and Substance-Related Mental Disorders; Sexually Transmitted Diseases
Interventions: Behavioral: Brief Intervention (BI) with Technology Extender; Other: Brochure
Sponsors: The Miriam Hospital; Planned Parenthood of Southern New England; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Pain; Alcohol Drinking; Acute Pain; Drinking Behavior
Interventions: Drug: Low Alcohol; Drug: Moderate Alcohol; Drug: Placebo Alcohol; Other: Pain Induction; Other: No Pain Induction
Sponsors: Syracuse University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: NAFLD; Diabetes Mellitus, Type 2; Hypertriglyceridemia; Fatty Liver, Nonalcoholic
Interventions: Drug: ISIS 703802; Drug: Placebo
Sponsors: Akcea Therapeutics; Ionis Pharmaceuticals, Inc.
Recruiting - Conditions: HIV/AIDS; Dysglycemia; Alcohol Use Disorder
Intervention: Behavioral: Exercise
Sponsor: Louisiana State University Health Sciences Center in New Orleans
Recruiting - Condition: Alcohol Drinking
Interventions: Drug: Alcohol (Oral); Drug: Alcohol (IV); Drug: Alcohol (Ethanol)
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Suicide, Attempted; Drug Use; Alcohol; Use, Problem
Interventions: Behavioral: Brief intervention to prevent suicide attempt; Behavioral: Enhanced treatment as usual
Sponsors: University of Rochester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Alcohol Use Disorder; Depressive Disorder; Cigarette Smoking
Intervention: Device: Intermittent theta burst transcranial magnetic stimulation
Sponsor: Stanford University
Recruiting - Conditions: HIV Infection; Alcohol Use; Pain
Interventions: Drug: Low dose naltrexone; Drug: Nalmefene
Sponsors: Boston Medical Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Lacosamide; Drug: Placebo oral capsule
Sponsors: Boston Medical Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Drinking Heavy; Drinking Behavior; Drinking Excessive
Interventions: Behavioral: Motivational Enhancement Therapy and Strengths Based Case Management (MET/SBCM); Other: Alcohol education brochure
Sponsors: University of California, Los Angeles; University of California, San Diego; Providence Health & Services; Northeastern University
Recruiting - Conditions: Opioid-use Disorder; Harmful; Use, Alcohol
Intervention: Drug: Nalmefene
Sponsors: Yale University; First Pavlov State Medical University in St. Petersburg, Russia
Recruiting - Conditions: Major Depression; Alcohol Use Disorder
Interventions: Drug: allogeneic human mesenchymal stem cells (allo-hMSCs); Drug: Placebo
Sponsors: Joshua M Hare; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Use Disorder
Intervention: Behavioral: Drinking Options - Motivate, Shared Decisions, Telemonitor (DO-MoST)
Sponsor: VA Office of Research and Development
Not yet recruiting - Condition: Alcohol Use Disorder
Intervention: Drug: Pregabalin
Sponsor: New York State Psychiatric Institute
Recruiting - Condition: Alcohol Use Disorder
Interventions: Other: Placebo; Drug: Phytocannabinoid cannabidiol (CBD)
Sponsors: New York University School of Medicine; National Institutes of Health (NIH)
Not yet recruiting - Condition: Alcohol Abuse
Interventions: Behavioral: Enhanced Intervention; Behavioral: Standard Intervention
Sponsors: Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Cocaine Dependence; Alcohol Dependence
Interventions: Device: Real cTBS; Device: Sham cTBS
Sponsors: Medical University of South Carolina; National Institute on Drug Abuse (NIDA)
Recruiting - Conditions: Alcohol Dependence, in Remission; Addiction, Alcohol
Interventions: Drug: Exenatide 2 MG Injection; Drug: BD PosiFlush (saline)
Sponsors: Anders Fink-Jensen, MD, DMSci; The Novavì outpatient clinics, Copenhagen; Neurobiology Research Unit, Rigshospitalet, Copenhagen; Section of Biostatistics University of Copenhagen, Copenhagen
Recruiting - Conditions: Alcohol Use Disorder; Anxiety Disorders
Interventions: Behavioral: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders; Behavioral: Take Control
Sponsor: Boston University Charles River Campus
Recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Alcohol; Drug: Placebos; Drug: N-acetyl cysteine
Sponsors: William Stoops; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcoholism
Interventions: Dietary Supplement: Ketogenic Diet (KD); Dietary Supplement: Standard American (SA) Meals and Shakes
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Liver Failure; Liver Diseases, Alcoholic; Liver Diseases; Pain, Postoperative; Transplant; Failure, Liver; Liver Cirrhosis, Biliary
Intervention: Device: BRIDGE device
Sponsor: Duke University
Recruiting - Condition: Substance Abuse
Intervention: Behavioral: Coaching
Sponsor: VA Office of Research and Development
Recruiting - Condition: Alcoholism
Interventions: Behavioral: Individualized Assess & Treatment (IATP); Behavioral: Packaged Cognitive-Behavioral (PCBT); Behavioral: Case Management (CaseM)
Sponsors: UConn Health; Ronald M. Kadden; Howard Tennen
Recruiting - Conditions: Depressive Disorder; Anxiety Disorder; Somatoform Disorder; Alcohol Use Disorder
Intervention: Other: collaborative and stepped care model
Sponsors: Universitätsklinikum Hamburg-Eppendorf; Center for Health Care Research Hamburg; Hamburg Center for Health Economics
Recruiting - Condition: Alcohol Use Disorder
Interventions: Device: Active rTMS; Device: Sham rTMS
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Alcohol Use Disorder; Post Traumatic Stress Disorder
Intervention: Other: Computerized Plasticity-Based Adaptive Cognitive Training
Sponsors: Posit Science Corporation; VA Palo Alto Health Care System
Recruiting - Conditions: Sexual Assault and Rape; Risk Behavior; Alcohol Abuse
Interventions: Other: Social Norms Questionnaire; Other: Standardized Interview; Other: Group Discussion
Sponsors: Womack Army Medical Center; Rhode Island Hospital; University of North Carolina, Charlotte
Recruiting - Condition: ALD - Alcoholic Liver Disease
Intervention: Other: Blood draw
Sponsor: The Cleveland Clinic
Recruiting - Condition: PTSD and Alcohol Use Disorder
Interventions: Drug: topiramate; Behavioral: prolonged exposure; Drug: placebo
Sponsors: VA Office of Research and Development; University of California, San Diego
Recruiting - Conditions: Depression; Anxiety; Somatoform Disorders; Alcohol Abuse
Intervention:
Sponsors: Charite University, Berlin, Germany; German Federal Ministry of Education and Research
Recruiting - Condition: Alcoholic Liver Disease
Intervention: Other: Biopsies
Sponsor: The Cleveland Clinic
Recruiting - Condition: Alcohol Abuse
Interventions: Drug: Bupropion; Drug: Placebo Oral Tablet
Sponsors: University of North Carolina, Chapel Hill; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Substance Abuse; Risk Reduction; RIsky Sexual Behavior
Interventions: Behavioral: Handbook condition; Behavioral: Handbook plus condition
Sponsor: Washington State University
Recruiting - Condition: Alcoholism
Intervention:
Sponsors: National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute on Drug Abuse (NIDA); The Peter G. Dodge Foundation (PGDF)
Recruiting - Condition: Alcohol Abstinence
Interventions: Drug: Guanfacine XR 3mgs/daily; Drug: Placebo (for guanfacine)
Sponsor: Stony Brook University
Recruiting - Condition: Alcohol Use Disorder
Interventions: Other: Affective Training; Other: Neutral Training
Sponsors: University of Florida; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol; Harmful Use
Intervention: Behavioral: E-alcohol therapy
Sponsors: University of Southern Denmark; TRYG Foundation; Novavi Outpatient Clinics
Recruiting - Condition: Psychomotor Impairment
Interventions: Drug: delta 9 tetrahydrocannabinol; Drug: placebo delta 9 tetrahydrocannabinol; Drug: Alcohol; Drug: Placebo alcohol
Sponsors: Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR); Health Canada
Recruiting - Conditions: HBV; Alcoholic Hepatitis; Liver Fibroses
Intervention: Other: Estimates - prevalence of lifetime/chronic HBV infection
Sponsors: University of Alabama at Birmingham; University Teaching Hospital; Tropical Gastroenterology and Nutrition Group; Centre for Infectious Disease Research in Zambia; Ministry of Health, Zambia
Recruiting - Condition: Unhealthy Alcohol Use
Interventions: Behavioral: Contingency Management Counseling; Behavioral: Addiction Physician Management; Behavioral: Motivational Enhancement Therapy
Sponsors: Yale University; VA Connecticut Healthcare System; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: HIV Infections
Interventions: Behavioral: YouTHrive; Behavioral: Information-only Control
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of North Carolina; University of Michigan; Emory University; Children's Hospital of Philadelphia; Texas Children's Hospital; Cook County Hospital; Montefiore Medical Center; University of South Florida
Recruiting - Condition: Alcohol Use Disorder (AUD)
Interventions: Device: Recovery Navigator on an as needed basis up to 6 months; Device: Recovery Navigator prior to hospital discharge; Other: No interaction with Recovery Navigator
Sponsor: University of Colorado, Denver
Recruiting - Condition: Alcohol Use
Interventions: Drug: Oxytocin; Drug: Placebo
Sponsor: Medical University of South Carolina
Recruiting - Condition: Alcohol-Related Disorders
Interventions: Other: Melatonin; Other: Placebo
Sponsor: Centre for Addiction and Mental Health
Recruiting - Condition: Alcoholism
Interventions: Behavioral: Retrieval-Extinction Learning; Other: rTMS; Other: SAM
Sponsors: Hospital Universitario 12 de Octubre; Ministerio de Sanidad, Servicios Sociales e Igualdad
Recruiting - Condition: Severe Alcoholic Hepatitis
Interventions: Other: Fecal Microbiota Transplantation; Drug: Steroids
Sponsor: Institute of Liver and Biliary Sciences, India
Recruiting - Condition: Alcohol Use Disorder
Interventions: Other: [11C]-(+)-PHNO PET scan; Other: Alcohol Self-Administration; Other: Craving Task; Other: MRI scan; Other: Neuropsychological Assessment
Sponsor: Centre for Addiction and Mental Health
Recruiting - Condition: Alcoholism
Intervention: Behavioral: Retrieval-Extinction Learning
Sponsors: Gabriel Rubio Valladolid, MD; Hospital Universitario 12 de Octubre; Instituto de Salud Carlos III
Recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Topiramate; Drug: placebo
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Alcohol Drinking; Cigarette Smoking Toxicity
Intervention: Drug: Reduced nicotine cigarettes
Sponsor: Battelle Memorial Institute
Recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Mifepristone; Drug: Placebo - Cap
Sponsors: Johns Hopkins University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Post Traumatic Stress Disorder (PTSD); Addiction; Alcohol Abuse
Interventions: Drug: N-Acetylcysteine (NAC) Treatment; Behavioral: Cognitive Behavioral Therapy; Drug: Placebo Oral Capsule
Sponsors: Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes of Health (NIH)
Recruiting - Conditions: Alcohol Use; Alcohol Drinking; Drinking Behavior
Interventions: Other: Smartphone breathalyzer device/app use; Other: BAC estimator app use; Other: Text messaging procedure
Sponsors: University of Florida; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Dependence
Interventions: Device: medial prefrontal cortex; Device: dorsolateral prefrontal cortex; Device: sham stimulation
Sponsor: Medical University of South Carolina
Recruiting - Condition: Alcohol Dependance
Interventions: Device: medial prefrontal cortex; Device: dorsolateral prefrontal cortex; Device: sham
Sponsors: Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Condomless Sex; Human Immunodeficiency Virus (HIV); Sexually Transmitted Infections (STIs); Alcohol and Drug Use; Violence and Victimization; Access and Linkage to Healthcare; Education Advancement
Interventions: Behavioral: Young Women's Health CoOp (YWHC); Behavioral: Standard HTC
Sponsors: RTI International; South African Medical Research Council, SAMRC
Recruiting - Conditions: HIV Positive; Alcohol Use
Interventions: Behavioral: Computerized Brief Intervention (CBI); Behavioral: CBT4CBT; Drug: Recommendation and Counseling for Alcohol Pharmacotherapy
Sponsor: University of Alabama at Birmingham
Recruiting - Condition: Substance Use Disorders
Interventions: Behavioral: Critical Dialogue; Behavioral: Capacity Building Project; Behavioral: Quality of Life Wheel; Behavioral: PF; Behavioral: LC
Sponsors: University of Illinois at Urbana-Champaign; National Development and Research Institutes, Inc.; North Jersey Community Research Initiative; University of Michigan; National Institute on Minority Health and Health Disparities (NIMHD)
Recruiting - Conditions: Alcohol Use Disorder; PTSD; Cognitive Dysfunction
Interventions: Behavioral: Cognitive Training; Behavioral: Cognitive training placebo control
Sponsor: VA Office of Research and Development
Recruiting - Conditions: HIV; Partner Violence; Malnutrition; Alcohol Use/Abuse; Depression
Interventions: Behavioral: Accountable Condition; Behavioral: Control Condition
Sponsors: University of California, Los Angeles; National Institute of Mental Health (NIMH); University of Stellenbosch
Recruiting - Condition: Alcohol Consumption
Interventions: Behavioral: Drinking Cognition Feedback (DCF); Behavioral: Alcohol Risk Feedback (ARF); Behavioral: Adaptive Goal Support (AGS); Behavioral: COMBO
Sponsors: University of Pittsburgh; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: HIV; Alcohol Use Disorders
Intervention: Other: Transitional HIV care for prison releasees
Sponsors: University of North Carolina, Chapel Hill; National Institutes of Health (NIH); John E. Fogarty International Center (FIC)
Recruiting - Conditions: Posttraumatic Stress Disorder (PTSD); Alcohol Use Disorder (AUD); Substance Use Disorder (SUD)
Interventions: Drug: N-acetylcysteine; Drug: Placebo; Behavioral: Cognitive behavioral therapy
Sponsors: Medical University of South Carolina; United States Department of Defense; Institute for Translational Neuroscience
Recruiting - Condition: Hypertension
Interventions: Drug: Dehydrated alcohol; Device: Peregrine System Kit (Sham Procedure)
Sponsor: Ablative Solutions, Inc.
Not yet recruiting - Conditions: PTSD; Alcohol Use Disorder
Interventions: Drug: Pregabalin plus BBCET; Other: Placebo plus BBCET
Sponsors: University of Maryland; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Smoking Cessation; Alcohol Drinking
Interventions: Drug: Chantix; Behavioral: Behavioral Counseling Sessions; Drug: NicodermCQ
Sponsors: University of Chicago; Pfizer
Recruiting - Conditions: Tuberculosis; Alcohol Consumption; Treatment Adverse Effect
Intervention: Behavioral: DOT Adherence Monitoring
Sponsors: Boston Medical Center; Medical Research Council, South Africa; Boston University; University of Cape Town; National Institute of Allergy and Infectious Diseases (NIAID); University of Stellenbosch
Recruiting - Conditions: Alcohol Drinking; Alcohol Drinking Related Problems
Interventions: Behavioral: Retrieval-extinction; Behavioral: Extinction; Behavioral: Retrieval
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - Condition: Alcohol Use
Intervention: Behavioral: Brief Negotiational Intervention
Sponsors: Duke University; Kilimanjaro Christian Medical Centre, Tanzania; John E. Fogarty International Center (FIC)
Recruiting - Conditions: Cirrhosis; Alcohol Dependence; Nalmefene
Interventions: Drug: Nalmefene (Selincro®) 18 mg tablet; Drug: placebo
Sponsor: Centre Hospitalier Universitaire, Amiens
Not yet recruiting - Conditions: Posttraumatic Stress Disorder; Alcohol Use Disorders
Intervention: Behavioral: Brief Cognitive Therapy
Sponsors: University of Washington; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: HIV Infection; Alcohol Use; Smoking
Interventions: Drug: Varenicline; Drug: Cytisine; Drug: Nicotine Replacement Therapy; Drug: Varenicline Placebo; Drug: Cytisine Placebo; Drug: Nicotine Replacement Therapy Placebo
Sponsors: Boston Medical Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Obesity
Interventions: Other: Oral Alcohol challenge test Alcohol visit first; Other: Oral Alcohol challenge test Placebo visit first; Other: Intravenous Alcohol Challenge Test (Clamp); Other: Intravenous Alcohol Self-administration Test
Sponsors: University of Illinois at Urbana-Champaign; Carle Foundation Hospital
Recruiting - Condition: Alcohol Use Disorder
Interventions: Behavioral: Individual clinician-provided CBT; Behavioral: CBT4CBT
Sponsor: Yale University
Recruiting - Conditions: Alcohol Abuse; Impulsive Behavior
Interventions: Drug: Tolcapone; Drug: Placebo
Sponsor: University of California, San Francisco
Recruiting - Condition: Fetal Alcohol Spectrum Disorders
Interventions: Drug: Choline bitartrate; Drug: Placebo
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting - Condition: Alcohol Use Disorder
Intervention: Drug: Disulfiram
Sponsor: New York State Psychiatric Institute
Recruiting - Condition: Alcoholism
Interventions: Drug: BACLOFEN; Drug: PLACEBO
Sponsor: Nantes University Hospital
Recruiting - Condition: Alcoholism
Interventions: Drug: Oxytocin; Other: Placebo
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - Condition: Alcohol Dependence
Interventions: Behavioral: LPA+Fitbit; Behavioral: HEC
Sponsors: Butler Hospital; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcoholism
Interventions: Drug: PF-05190457; Behavioral: MI-VF; Other: Placebo; Other: Counseling
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Use Disorder Cognitive Decline
Intervention: Behavioral: Cognitive Remediation Training
Sponsor: VA Office of Research and Development
Recruiting - Condition: Hypertrophic Obstructive Cardiomyopathy
Intervention: Drug: Aspirin
Sponsor: Ottawa Heart Institute Research Corporation
Recruiting - Condition: Alcohol Consumption
Interventions: Drug: Placebo; Drug: 10 mg Obeticholic Acid (OCA)
Sponsors: Suthat Liangpunsakul; National Institute on Alcohol Abuse and Alcoholism (NIAAA); Intercept Pharmaceuticals
Recruiting - Condition: Primary Alcohol Use Disorder
Interventions: Drug: Ketamine; Drug: Placebo; Behavioral: Psychological Therapy; Behavioral: Alcohol Education
Sponsor: University College, London
Recruiting - Conditions: Cardiovascular Disease (CVD); Hypertension; Hyperlipemia; Obesity
Intervention: Other: Community-based peer health coach intervention
Sponsor: VA Office of Research and Development
Recruiting - Condition: Alcohol Drinking
Interventions: Drug: Nalmefene; Other: Placebo
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Coronary; Ischemic; Arrhythmias, Cardiac; Heart Failure; Peripheral Vascular Diseases; Dementia; Stroke; Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency; Alcoholism; Cancer; Diabetes; Renal Insufficiency
Interventions: Procedure: OPTI-AGED; Procedure: Usual Care
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Fetal Alcohol Syndrome
Intervention:
Sponsor: Northwestern University
Recruiting - Condition: Alcohol Use Disorder
Intervention: Drug: Baclofen
Sponsors: University Hospital, Lille; Région Nord-Pas de Calais, France; Groupement Interrégional de Recherche Clinique et d'Innovation
Recruiting - Condition: Alcohol Dependence
Intervention:
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Substance Use Disorder
Interventions: Behavioral: Resonance Breathing; Behavioral: Non-Resonance Breathing
Sponsors: Rutgers, The State University of New Jersey; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Posttraumatic Stress Disorder; Alcohol Use Disorders
Interventions: Drug: doxazosin; Drug: placebo
Sponsors: VA Office of Research and Development; Medical University of South Carolina; Consortium to Alleviate PTSD
Recruiting - Conditions: Unhealthy Alcohol Use; Alcohol Use Disorders
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Conditions: Major Depressive Disorder; Alcohol Use Disorder
Interventions: Drug: Ketamine + Naltrexone; Drug: Ketamine + Placebo; Drug: Placebo (psychoactive placebo midazolam) + Placebo
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Alcohol Dependence; Alcohol Use Disorder
Intervention: Drug: XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
Sponsors: New York University School of Medicine; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Fear; Stress; Alcohol Dependence
Intervention:
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcoholic Hepatitis
Interventions: Drug: Bovine Colostrum; Drug: Placebo
Sponsor: Dayanand Medical College and Hospital
Recruiting - Condition: Alcoholic Hepatitis
Interventions: Drug: G-CSF (Filgrastim injection); Drug: steroid; Drug: placebo
Sponsor: Chuncheon Sacred Heart Hospital
Recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Ondansetron; Drug: Placebo
Sponsors: University of Maryland; University of Pennsylvania
Recruiting - Condition: Alcoholism
Interventions: Drug: Topiramate; Behavioral: Medical Management; Drug: Inactive Placebo
Sponsors: University of Pennsylvania; National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes of Health (NIH); Department of Health and Human Services; Corporal Michael J. Crescenz VA Medical Center
Recruiting - Conditions: Alcohol Use Disorder; PTSD
Interventions: Drug: Prazosin; Drug: Naltrexone; Drug: (Praz)Placebo; Drug: (Nal)Placebo
Sponsors: Seattle Institute for Biomedical and Clinical Research; United States Department of Defense; VA Puget Sound Health Care System
Recruiting - Condition: Alcoholism
Intervention: Behavioral: Cognitive Behavioral Coping Skills Therapy
Sponsor: New York State Psychiatric Institute
Recruiting - Conditions: Infection; Alcohol Abuse; Drugs of Abuse; Lung Injury
Intervention: Other: Characterize alcohol and drug use
Sponsors: University of Colorado, Denver; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Risk Reduction Behavior
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - Condition: Alcohol Dependence
Interventions: Behavioral: Computerized Alcohol Screening; Behavioral: Brief Negotiated Interview
Sponsor: Yale University
Recruiting - Condition: Alcohol Use Disorders (AUD)
Intervention: Drug: Mifepristone 600-mg/day or placebo for a week
Sponsor: Brown University
Recruiting - Conditions: Alcoholic Hepatitis; Alcoholic Liver Disease
Interventions: Drug: Amoxicillin; Drug: Placebo; Drug: Prednisolone
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Condition: Alcoholism
Intervention:
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcoholism
Interventions: Device: MRI; Drug: C-11PBR28; Drug: F-18FDG
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Dependence
Interventions: Drug: Minocycline; Drug: Placebo (for Minocycline)
Sponsors: Yale University; United States Department of Defense
Recruiting - Condition: Alcohol Drinking
Interventions: Drug: Guanfacine 3mg/day; Drug: Guanfacine 1.5mg/day; Drug: Placebo
Sponsors: Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: CBT Decoupling; CBT Anxiety Reduction; CBT Combined
Interventions: Behavioral: De-coupling; Behavioral: Anxiety Reduction; Behavioral: Combined
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting - Conditions: Evaluating NIAAA's Alcohol Screener; Evaluating a Brief Intervention
Interventions: Behavioral: Brief Intervention; Behavioral: Brief Intervention with Coaching; Behavioral: Treatment as Usual
Sponsors: University of Rhode Island; Brown University
Recruiting - Conditions: Alcohol Dependence; Alcohol Drinking; Alcoholism
Intervention:
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Alcohol Dependence; Alcohol Drinking; Alcohol-Related Disorders; Alcoholism; Brain Mapping
Intervention:
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcoholic Hepatitis
Intervention:
Sponsors: University of Pittsburgh; National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Wisconsin, Madison; King's College London; Veterans Medical Research Foundation; Hospital Vall d'Hebron; Institut National de la Santé Et de la Recherche Médicale, France; Yale University; Columbia University; Weill Medical College of Cornell University; University of Alberta; Hospital San Jose Tec de Monterrey
Recruiting - Conditions: Unhealthy Alcohol Use; Alcohol Use Disorder; Alcohol Disorders
Intervention: Behavioral: Relational Agent Intervention
Sponsors: VA Office of Research and Development; Northeastern University; Boston University
Recruiting - Conditions: Alcohol Use; AA Attendance; Sexual Risk Behavior
Intervention: Other: Introduction to AA volunteer
Sponsor: Butler Hospital
Recruiting - Condition: Acute Alcoholic Hepatitis
Interventions: Dietary Supplement: Lactobacillus Rhamnosus GG; Drug: Placebo for Probiotic
Sponsors: University of Texas Southwestern Medical Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA); The Cleveland Clinic; University of Massachusetts, Worcester; University of Louisville
Recruiting - Condition: Obesity
Interventions: Other: Alcohol challenge test Alcohol visit first; Other: Alcohol challenge test Placebo visit first
Sponsors: University of Illinois at Urbana-Champaign; University of Missouri-Columbia; Washington University School of Medicine
Recruiting - Conditions: Rare Disorders; Undiagnosed Disorders; Disorders of Unknown Prevalence; Cornelia De Lange Syndrome; Prenatal Benign Hypophosphatasia; Perinatal Lethal Hypophosphatasia; Odontohypophosphatasia; Adult Hypophosphatasia; Childhood-onset Hypophosphatasia; Infantile Hypophosphatasia; Hypophosphatasia; Kabuki Syndrome; Bohring-Opitz Syndrome; Narcolepsy Without Cataplexy; Narcolepsy-cataplexy; Hypersomnolence Disorder; Idiopathic Hypersomnia Without Long Sleep Time; Idiopathic Hypersomnia With Long Sleep Time; Idiopathic Hypersomnia; Kleine-Levin Syndrome; Kawasaki Disease; Leiomyosarcoma; Leiomyosarcoma of the Corpus Uteri; Leiomyosarcoma of the Cervix Uteri; Leiomyosarcoma of Small Intestine; Acquired Myasthenia Gravis; Addison Disease; Hyperacusis (Hyperacousis); Juvenile Myasthenia Gravis; Transient Neonatal Myasthenia Gravis; Williams Syndrome; Lyme Disease; Myasthenia Gravis; Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome); Isolated Klippel-Feil Syndrome; Frasier Syndrome; Denys-Drash Syndrome; Beckwith-Wiedemann Syndrome; Emanuel Syndrome; Isolated Aniridia; Beckwith-Wiedemann Syndrome Due to Paternal Uniparental Disomy of Chromosome 11; Beckwith-Wiedemann Syndrome Due to Imprinting Defect of 11p15; Beckwith-Wiedemann Syndrome Due to 11p15 Translocation/Inversion; Beckwith-Wiedemann Syndrome Due to 11p15 Microduplication; Beckwith-Wiedemann Syndrome Due to 11p15 Microdeletion; Axenfeld-Rieger Syndrome; Aniridia-intellectual Disability Syndrome; Aniridia - Renal Agenesis - Psychomotor Retardation; Aniridia - Ptosis - Intellectual Disability - Familial Obesity; Aniridia - Cerebellar Ataxia - Intellectual Disability; Aniridia - Absent Patella; Aniridia; Peters Anomaly - Cataract; Peters Anomaly; Potocki-Shaffer Syndrome; Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11; Silver-Russell Syndrome Due to Imprinting Defect of 11p15; Silver-Russell Syndrome Due to 11p15 Microduplication; Syndromic Aniridia; WAGR Syndrome; Wolf-Hirschhorn Syndrome; 4p16.3 Microduplication Syndrome; 4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome; Autosomal Recessive Stickler Syndrome; Stickler Syndrome Type 2; Stickler Syndrome Type 1; Stickler Syndrome; Mucolipidosis Type 4; X-linked Spinocerebellar Ataxia Type 4; X-linked Spinocerebellar Ataxia Type 3; X-linked Intellectual Disability - Ataxia - Apraxia; X-linked Progressive Cerebellar Ataxia; X-linked Non Progressive Cerebellar Ataxia; X-linked Cerebellar Ataxia; Vitamin B12 Deficiency Ataxia; Toxic Exposure Ataxia; Unclassified Autosomal Dominant Spinocerebellar Ataxia; Thyroid Antibody Ataxia; Sporadic Adult-onset Ataxia of Unknown Etiology; Spinocerebellar Ataxia With Oculomotor Anomaly; Spinocerebellar Ataxia With Epilepsy; Spinocerebellar Ataxia With Axonal Neuropathy Type 2; Spinocerebellar Ataxia Type 8; Spinocerebellar Ataxia Type 7; Spinocerebellar Ataxia Type 6; Spinocerebellar Ataxia Type 5; Spinocerebellar Ataxia Type 4; Spinocerebellar Ataxia Type 37; Spinocerebellar Ataxia Type 36; Spinocerebellar Ataxia Type 35; Spinocerebellar Ataxia Type 34; Spinocerebellar Ataxia Type 32; Spinocerebellar Ataxia Type 31; Spinocerebellar Ataxia Type 30; Spinocerebellar Ataxia Type 3; Spinocerebellar Ataxia Type 29; Spinocerebellar Ataxia Type 28; Spinocerebellar Ataxia Type 27; Spinocerebellar Ataxia Type 26; Spinocerebellar Ataxia Type 25; Spinocerebellar Ataxia Type 23; Spinocerebellar Ataxia Type 22; Spinocerebellar Ataxia Type 21; Spinocerebellar Ataxia Type 20; Spinocerebellar Ataxia Type 2; Spinocerebellar Ataxia Type 19/22; Spinocerebellar Ataxia Type 18; Spinocerebellar Ataxia Type 17; Spinocerebellar Ataxia Type 16; Spinocerebellar Ataxia Type 15/16; Spinocerebellar Ataxia Type 14; Spinocerebellar Ataxia Type 13; Spinocerebellar Ataxia Type 12; Spinocerebellar Ataxia Type 11; Spinocerebellar Ataxia Type 10; Spinocerebellar Ataxia Type 1 With Axonal Neuropathy; Spinocerebellar Ataxia Type 1; Spinocerebellar Ataxia - Unknown; Spinocerebellar Ataxia - Dysmorphism; Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature; Spectrin-associated Autosomal Recessive Cerebellar Ataxia; Spasticity-ataxia-gait Anomalies Syndrome; Spastic Ataxia With Congenital Miosis; Spastic Ataxia - Corneal Dystrophy; Spastic Ataxia; Rare Hereditary Ataxia; Rare Ataxia; Recessive Mitochondrial Ataxia Syndrome; Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature; Posterior Column Ataxia - Retinitis Pigmentosa; Post-Stroke Ataxia; Post-Head Injury Ataxia; Post Vaccination Ataxia; Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract; Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus; Non-progressive Cerebellar Ataxia With Intellectual Disability; Non-hereditary Degenerative Ataxia; Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity; Olivopontocerebellar Atrophy - Deafness; NARP Syndrome; Myoclonus - Cerebellar Ataxia - Deafness; Multiple System Atrophy, Parkinsonian Type; Multiple System Atrophy, Cerebellar Type; Multiple System Atrophy; Maternally-inherited Leigh Syndrome; Machado-Joseph Disease Type 3; Machado-Joseph Disease Type 2; Machado-Joseph Disease Type 1; Lethal Ataxia With Deafness and Optic Atrophy; Leigh Syndrome; Leukoencephalopathy With Mild Cerebellar Ataxia and White Matter Edema; Leukoencephalopathy - Ataxia - Hypodontia - Hypomyelination; Leigh Syndrome With Nephrotic Syndrome; Leigh Syndrome With Leukodystrophy; Leigh Syndrome With Cardiomyopathy; Late-onset Ataxia With Dementia; Intellectual Disability-hyperkinetic Movement-truncal Ataxia Syndrome; Infection or Post Infection Ataxia; Infantile-onset Autosomal Recessive Nonprogressive Cerebellar Ataxia; Infantile Onset Spinocerebellar Ataxia; GAD Ataxia; Hereditary Episodic Ataxia; Gliadin/Gluten Ataxia; Friedreich Ataxia; Fragile X-associated Tremor/Ataxia Syndrome; Familial Paroxysmal Ataxia; Exposure to Medications Ataxia; Episodic Ataxia With Slurred Speech; Episodic Ataxia Unknown Type; Episodic Ataxia Type 7; Episodic Ataxia Type 6; Episodic Ataxia Type 5; Episodic Ataxia Type 4; Episodic Ataxia Type 3; Episodic Ataxia Type 1; Epilepsy and/or Ataxia With Myoclonus as Major Feature; Early-onset Spastic Ataxia-neuropathy Syndrome; Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity; Early-onset Cerebellar Ataxia With Retained Tendon Reflexes; Early-onset Ataxia With Dementia; Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia; Dilated Cardiomyopathy With Ataxia; Cataract - Ataxia - Deafness; Cerebellar Ataxia, Cayman Type; Cerebellar Ataxia With Peripheral Neuropathy; Cerebellar Ataxia - Hypogonadism; Cerebellar Ataxia - Ectodermal Dysplasia; Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss; Brain Tumor Ataxia; Brachydactyly - Nystagmus - Cerebellar Ataxia; Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia; Autosomal Recessive Syndromic Cerebellar Ataxia; Autosomal Recessive Spastic Ataxia With Leukoencephalopathy; Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay; Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria; Autosomal Recessive Spastic Ataxia; Autosomal Recessive Metabolic Cerebellar Ataxia; Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine; Autosomal Recessive Ataxia, Beauce Type; Autosomal Recessive Ataxia Due to Ubiquinone Deficiency; Autosomal Recessive Ataxia Due to PEX10 Deficiency; Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia; Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency; Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency; Autosomal Recessive Congenital Cerebellar Ataxia; Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome; Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency; Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency; Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency; Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome; Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity; Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency; Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect; Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion; Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation; Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness; Autosomal Recessive Cerebellar Ataxia; Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly; Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation; Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy; Autosomal Dominant Spastic Ataxia Type 1; Autosomal Dominant Spastic Ataxia; Autosomal Dominant Optic Atrophy; Ataxia-telangiectasia Variant; Ataxia-telangiectasia; Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy; Autosomal Dominant Cerebellar Ataxia Type 4; Autosomal Dominant Cerebellar Ataxia Type 3; Autosomal Dominant Cerebellar Ataxia Type 2; Autosomal Dominant Cerebellar Ataxia Type 1; Autosomal Dominant Cerebellar Ataxia; Ataxia-telangiectasia-like Disorder; Ataxia-intellectual Disability-oculomotor Apraxia-cerebellar Cysts Syndrome; Ataxia-deafness-intellectual Disability Syndrome; Ataxia With Vitamin E Deficiency; Ataxia With Dementia; Ataxia Neuropathy Spectrum; Ataxia - Tapetoretinal Degeneration; Ataxia - Photosensitivity - Short Stature; Ataxia - Pancytopenia; Ataxia - Oculomotor Apraxia Type 1; Ataxia - Hypogonadism - Choroidal Dystrophy; Ataxia - Other; Ataxia - Genetic Diagnosis - Unknown; Acquired Ataxia; Adult-onset Autosomal Recessive Cerebellar Ataxia; Alcohol Related Ataxia; Multiple Endocrine Neoplasia; Multiple Endocrine Neoplasia Type II; Multiple Endocrine Neoplasia Type 1; Multiple Endocrine Neoplasia Type 2; Multiple Endocrine Neoplasia, Type IV; Multiple Endocrine Neoplasia, Type 3; Multiple Endocrine Neoplasia (MEN) Syndrome; Multiple Endocrine Neoplasia Type 2B; Multiple Endocrine Neoplasia Type 2A; Atypical Hemolytic Uremic Syndrome; Atypical HUS; Wiedemann-Steiner Syndrome; Breast Implant-Associated Anaplastic Large Cell Lymphoma; Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA); Hemophagocytic Lymphohistiocytosis; Behcet's Disease; Alagille Syndrome; Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD); Lowe Syndrome; Pitt Hopkins Syndrome
Intervention:
Sponsors: Sanford Health; National Ataxia Foundation; International WAGR Syndrome Association; 4p- Support Group; ML4 Foundation; Cornelia de Lange Syndrome Foundation; Stickler Involved People; Kawasaki Disease Foundation; Klippel-Feil Syndrome Alliance; Klippel-Feil Syndrome Freedom; Hyperacusis Research Limited; Hypersomnia Foundation; Kabuki Syndrome Network; Kleine-Levin Syndrome Foundation; Leiomyosarcoma Direct Research Foundation; Marinesco-Sjogren Syndrome Support Group; Mucolipidosis Type IV (ML4) Foundation; People with Narcolepsy 4 People with Narcolepsy (PWN4PWN); Soft Bones Incorporated; American Multiple Endocrine Neoplasia Support; Atypical Hemolytic Uremic Syndrome Foundation; All Things Kabuki; Wiedemann-Steiner Syndrome Foundation; Breast Implant Victim Advocates; PROS Foundation; American Behcet's Disease Association
Recruiting - Conditions: Alcohol Dependence; Posttraumatic Stress Disorder (PTSD)
Interventions: Drug: Topiramate; Drug: placebo
Sponsors: University of California, San Francisco; United States Department of Defense; San Francisco Veterans Affairs Medical Center; Northern California Institute of Research and Education
Recruiting - Conditions: Carcinoma, Hepatocellular; Liver Cirrhosis, Alcoholic; Hepatitis, Alcoholic; Hepatitis, Chronic; Hepatitis, Viral, Human
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - Condition: Alcoholic Intoxication
Interventions: Drug: Alcohol; Procedure: Self-Administration
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting
Clinical Trial Locations