Welcome to Paid Research Studies


  • Calibration Study of a Blood Alcohol Level Smart Watch

    Condition:   Alcohol Drinking
    Intervention:   Other: Smart watch to measure Blood Alcohol Level
    Sponsors:   Boston Medical Center;   KWJ Engineering;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Nicotinic Receptor Genetic Variation and Alcohol Reward

    Condition:   Alcohol Drinking
    Interventions:   Drug: Alcohol (Oral);   Drug: Alcohol (IV);   Drug: Alcohol (Ethanol)
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Improving Outcomes Among Medical/Surgical Inpatients With Alcohol Use Disorders

    Condition:   Alcohol Use Disorder
    Intervention:   Behavioral: Drinking Options - Motivate, Shared Decisions, Telemonitor (DO-MoST)
    Sponsor:   VA Office of Research and Development
    Recruiting
  • The Effect of rTMS to the Prefrontal Cortex in Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Device: active rTMS;   Behavioral: Inpatient admission;   Device: sham rTMS
    Sponsor:   New York State Psychiatric Institute
    Recruiting
  • Exploring Regulation and Function of Dopamine D3 Receptors in Alcohol Use Disorders: A [11C]-(+)-PHNO Study

    Condition:   Alcohol Use Disorder
    Interventions:   Other: [11C]-(+)-PHNO PET scan;   Other: Alcohol Self-Administration;   Other: Craving Task;   Other: MRI scan;   Other: Neuropsychological Assessment
    Sponsor:   Centre for Addiction and Mental Health
    Recruiting
  • Effects of Cannabidiol in Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Other: Placebo;   Drug: Phytocannabinoid cannabidiol (CBD)
    Sponsors:   New York University School of Medicine;   National Institutes of Health (NIH)
    Not yet recruiting
  • MCII for Alcohol Use Disorders

    Condition:   Alcohol Use Disorder
    Interventions:   Other: MCII;   Other: Treatment as usual
    Sponsors:   Susanne Rösner;   University of Konstanz;   Zurich University of Applied Sciences;   New York University;   University of Hamburg
    Recruiting
  • Alcohol Use and Mental Health - Pilot Test of Video-assisted Drinking Topography

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Beer;   Device: Videotaped drinking session
    Sponsor:   University of Florida
    Recruiting
  • Testing the Efficacy of an Online Integrated Treatment for Comorbid Alcohol Misuse and Emotional Problems

    Condition:   Alcohol Use Disorder
    Intervention:   Behavioral: Integrated Online CBT and MI
    Sponsor:   University of Manitoba
    Recruiting
  • Pregabalin as Treatment for Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Intervention:   Drug: Pregabalin
    Sponsor:   New York State Psychiatric Institute
    Recruiting
  • CBT4CBT With Spanish Alcohol Users

    Condition:   Alcohol Use Disorder
    Interventions:   Behavioral: Standard treatment (ST) PLUS web-based CBT4CBT;   Behavioral: Standard Treatment (ST)
    Sponsors:   Yale University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • A Machine Learning Approach for Inferring Alcohol Intoxication Levels From Gait Data

    Condition:   Alcohol Drinking
    Intervention:   Other: All Participants
    Sponsor:   Butler Hospital
    Recruiting
  • Study of Retinal Function Using Electroretinogram in Regular Alcohol Users

    Condition:   Alcohol Use Disorder
    Intervention:   Other: electroretinogram (flash, pattern and multifocal)
    Sponsor:   Centre Psychothérapique de Nancy
    Not yet recruiting
  • Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling

    Condition:   Alcohol Consumption
    Interventions:   Drug: Placebo;   Drug: 10 mg Obeticholic Acid (OCA)
    Sponsors:   Suthat Liangpunsakul;   National Institute on Alcohol Abuse and Alcoholism (NIAAA);   Intercept Pharmaceuticals
    Recruiting
  • Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Alcohol;   Drug: Placebos;   Drug: Duloxetine;   Drug: Methylphenidate
    Sponsors:   Craig Rush;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Influence of n-Acetylcysteine Maintenance on Alcohol Effects

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Alcohol;   Drug: Placebos;   Drug: N-acetyl cysteine
    Sponsors:   William Stoops;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • VR Assessment for Alcohol Related Brain Damage

    Condition:   Alcohol-Related Disorders
    Intervention:   Diagnostic Test: Validation Gate task
    Sponsors:   Universitat Pompeu Fabra;   Hospital Clinic of Barcelona;   Institute for Bioengineering of Catalonia
    Not yet recruiting
  • Alcohol Brief Intervention Plus Personalized Mobile Chat-based Intervention for High-risk Drinking University Students

    Condition:   Alcohol Drinking in College
    Interventions:   Behavioral: Mobile chat-based instant messages;   Behavioral: Alcohol brief intervention
    Sponsor:   The University of Hong Kong
    Not yet recruiting
  • A Targeted, Real-Time, Technology-Supported Intervention for Patients With Alcohol Use Disorder on Disulfiram

    Condition:   Drinking, Alcohol
    Interventions:   Behavioral: Wisepill+SMS;   Other: Wisepill-only
    Sponsor:   Butler Hospital
    Recruiting
  • Effects of a New Behavioral Intervention on Alcohol Craving and Drinking

    Conditions:   Alcohol Drinking;   Alcohol Drinking Related Problems
    Interventions:   Behavioral: Retrieval-extinction;   Behavioral: Extinction;   Behavioral: Retrieval
    Sponsor:   National Institute on Drug Abuse (NIDA)
    Recruiting
  • Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation

    Condition:   Alcohol Drinking
    Interventions:   Drug: Nalmefene;   Other: Placebo
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders

    Condition:   Alcohol Use Disorder
    Interventions:   Device: Active rTMS;   Device: Sham rTMS
    Sponsor:   VA Office of Research and Development
    Recruiting
  • Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)

    Condition:   Alcohol Abstinence
    Interventions:   Drug: Guanfacine XR 3mgs/daily;   Drug: Placebo (for guanfacine)
    Sponsor:   Stony Brook University
    Recruiting
  • Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Zonisamide;   Drug: Placebo
    Sponsors:   Virginia Commonwealth University;   University of Connecticut;   Yale University
    Recruiting
  • Training Inhibition in Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Other: Cognitive training;   Other: Control training
    Sponsor:   Assistance Publique - Hôpitaux de Paris
    Not yet recruiting
  • Contingency Management for Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Intervention:   Behavioral: DynamiCare Rewards
    Sponsors:   DynamiCare Health;   Johns Hopkins University
    Recruiting
  • Selective Attention in Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Intervention:  
    Sponsor:   Central Institute of Mental Health, Mannheim
    Recruiting
  • Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation

    Conditions:   Tobacco Use;   Alcohol Use, Unspecified
    Interventions:   Behavioral: Mindfulness Based Relapse Prevention - Smoking and Alcohol;   Behavioral: Cognitive Behavioral Therapy
    Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   National Institutes of Health (NIH);   National Center for Complementary and Integrative Health (NCCIH)
    Recruiting
  • Alcohol Intervention for First Year College Students

    Condition:   Underage Alcohol Use
    Interventions:   Behavioral: Text Messaging Intervention;   Behavioral: Active Control
    Sponsors:   University of North Texas Health Science Center;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Validation of a Training Program for Patients With Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Behavioral: SALIENCE;   Behavioral: TAU
    Sponsor:   Central Institute of Mental Health, Mannheim
    Recruiting
  • Ibudilast for the Treatment of Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Ibudilast;   Drug: Placebo oral capsule
    Sponsors:   University of California, Los Angeles;   National Institute on Alcohol Abuse and Alcoholism (NIAAA);   MediciNova
    Recruiting
  • Topiramate Treatment of Alcohol Use Disorders in African Americans

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Topiramate;   Drug: placebo
    Sponsor:   VA Office of Research and Development
    Recruiting
  • Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot Trial

    Condition:   Alcohol Use Disorder
    Intervention:   Device: Deep Brain Stimulation
    Sponsor:   Sunnybrook Health Sciences Centre
    Recruiting
  • Cerebellar Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Device: Repetitive transcranial magnetic stimulation (rTMS);   Device: Sham transcranial magnetic stimulation
    Sponsors:   The Mind Research Network;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Minocycline's Effects on Alcohol Responses in Humans

    Condition:   Alcohol Dependence
    Interventions:   Drug: Minocycline;   Drug: Placebo (for Minocycline)
    Sponsors:   Yale University;   United States Department of Defense
    Recruiting
  • Does Treatment With GLP-1 Reduce Alcohol Intake in Patients With Alcohol Dependence?

    Conditions:   Alcohol Dependence, in Remission;   Addiction, Alcohol
    Interventions:   Drug: Exenatide 2 MG Injection;   Drug: BD PosiFlush (saline)
    Sponsors:   Anders Fink-Jensen, MD, DMSci;   The Novavì outpatient clinics, Copenhagen;   Neurobiology Research Unit, Rigshospitalet, Copenhagen;   Section of Biostatistics University of Copenhagen, Copenhagen
    Recruiting
  • Improving Outcomes for Emergency Department Patients With Alcohol Problems

    Condition:   Drinking, Alcohol
    Interventions:   Behavioral: Alcohol Peer Mentor Intervention;   Behavioral: Brief Advice
    Sponsor:   VA Office of Research and Development
    Not yet recruiting
  • Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders

    Condition:   Alcohol Use Disorder
    Interventions:   Behavioral: Individual clinician-provided CBT;   Behavioral: CBT4CBT
    Sponsor:   Yale University
    Recruiting
  • N-Acetylcysteine for Adolescent Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: N-acetylcysteine;   Drug: Placebo oral capsule
    Sponsor:   Medical University of South Carolina
    Not yet recruiting
  • The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Exenatide;   Other: Sham injection
    Sponsors:   Boston Medical Center;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Fetal Alcohol Spectrum Disorder-Is This a Ciliopathy?

    Condition:   Fetal Alcohol Spectrum Disorder
    Intervention:   Diagnostic Test: Metabolomic analysis urine sample
    Sponsor:   University of Alberta
    Recruiting
  • Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders

    Conditions:   Alcohol Use Disorder;   Alcohol Dependence
    Interventions:   Drug: Rapamycin;   Drug: Placebo
    Sponsor:   Medical University of South Carolina
    Recruiting
  • Phone-based Safety Monitoring of Baclofen Prescriptions for Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Intervention:   Drug: Baclofen
    Sponsors:   University Hospital, Lille;   Région Nord-Pas de Calais, France;   Groupement Interrégional de Recherche Clinique et d'Innovation
    Recruiting
  • Pharmacogenetic Study of Ondansetron in Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Ondansetron;   Drug: Placebo
    Sponsors:   University of Maryland;   University of Pennsylvania
    Recruiting
  • Biomarkers to Measure Treatment Response for Alcohol Dependence

    Condition:   Alcohol Dependence
    Intervention:   Other: Alcohol administration
    Sponsor:   University of Maryland
    Recruiting
  • Human Alcohol Seeking Despite Aversion

    Condition:   Alcohol Abuse
    Interventions:   Behavioral: Aversive cue;   Behavioral: Neutral cue
    Sponsors:   Indiana University;   Purdue University
    Recruiting
  • Synergistic Effects of Anxiety and Alcohol Use Among Latinos and Its Sociocultural Mechanisms

    Conditions:   Alcohol Drinking;   Racism
    Interventions:   Other: Alcohol administration;   Other: Placebo;   Other: No Alcohol
    Sponsors:   University of Houston;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Nalmefene;   Drug: Baclofen;   Drug: Placebo Oral Capsule
    Sponsor:   Prof. Daniele Zullino
    Recruiting
  • Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking

    Conditions:   Smoking Cessation;   Alcohol Drinking
    Interventions:   Drug: Nicotine Replacement Therapy;   Drug: Bupropion;   Behavioral: Cognitive Behavioral Treatment;   Behavioral: Mobile Contingency Management
    Sponsor:   Duke University
    Recruiting
  • Genetic and Neural Factors in Alcohol-Related Cognition

    Condition:   Alcohol Abuse
    Intervention:   Behavioral: MRI Scanner
    Sponsors:   Virginia Commonwealth University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Oxytocin, Alcohol Craving, and Intimate Partner Aggression

    Condition:   Alcohol Use
    Interventions:   Drug: Oxytocin;   Drug: Placebo
    Sponsor:   Medical University of South Carolina
    Recruiting
  • Alcohol Biosensor Monitoring for Alcoholic Liver Disease

    Condition:   Alcohol Use, Unspecified
    Interventions:   Behavioral: Feedback;   Behavioral: Enhanced Usual Care
    Sponsors:   University of Pittsburgh;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • ARCH II Study (Alcohol Research Center on HIV Study II)

    Conditions:   Alcohol Consumption;   HIV;   Motivation
    Interventions:   Behavioral: Motivational Interviewing;   Other: Questionnaire assessment;   Other: Neurocognitive assessments;   Other: Blood specimens
    Sponsors:   University of Florida;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • A Tailored Physical Activity Smartphone App for Patients With Alcohol Dependence

    Condition:   Alcohol Dependence
    Interventions:   Behavioral: Fit&Sober App;   Behavioral: Brief Advice
    Sponsors:   Butler Hospital;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Talk Therapy by Phone to Promote Treatment for Alcohol Problems

    Conditions:   Alcohol Use Disorder;   Alcohol Abuse
    Interventions:   Behavioral: CBT by Phone to Promote Treatment;   Other: Reading the Subject a Pamphlet on Obtaining Alcohol Use Disorder Treatment
    Sponsors:   University of Rochester;   National Institutes of Health (NIH);   Medical University of South Carolina;   Syracuse University
    Not yet recruiting
  • Advanced Nurses vs. General Practitioners for the Management of Outpatient Alcohol Detox: a Safety and Cost Comparison

    Condition:   Alcohol Dependence
    Interventions:   Procedure: Advanced Nurse (AN);   Procedure: General Practitioner (GP)
    Sponsors:   University Hospital, Lille;   Ministry of Health, France
    Recruiting
  • Marijuana's Impact on Alcohol Motivation and Consumption

    Conditions:   Alcohol Drinking;   Marijuana
    Interventions:   Drug: THC 7.2%;   Drug: THC 3.0%;   Drug: Placebo
    Sponsors:   Brown University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Addressing Heavy Alcohol Use Consumption With Kudzu

    Conditions:   Alcohol Use Disorder;   Sexually Transmitted Diseases
    Interventions:   Drug: Standardized kudzu;   Other: Placebo
    Sponsors:   University of California, San Francisco;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Neuroscience-Informed Treatment Development for Adolescent Alcohol Use

    Conditions:   Alcohol Drinking;   Control
    Interventions:   Drug: N-Acetylcysteine;   Drug: Placebo Oral Capsule
    Sponsors:   Medical University of South Carolina;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Alcohol and Immune Response

    Conditions:   Alcohol Drinking;   Alcohol; Harmful Use
    Interventions:   Drug: Alcohol, Ethyl;   Other: Alcohol, Ethyl - placebo
    Sponsor:   Brown University
    Recruiting
  • AI for Alcohol Misuse in the EHR

    Conditions:   Alcohol Drinking;   Alcohol; Harmful Use;   Alcohol Abuse;   Trauma
    Intervention:   Other: Processing of clinical notes in the EHR data collected during routine care
    Sponsor:   Loyola University
    Not yet recruiting
  • Sex Differences in the Response to Abstinence From Alcohol.

    Condition:   Alcohol Use Disorder
    Interventions:   Behavioral: Abstinence from alcohol;   Behavioral: Usual drinking
    Sponsor:   Indiana University
    Not yet recruiting
  • Effects of Tolcapone on Decision Making and Alcohol Intake in Alcohol Users

    Conditions:   Alcohol Abuse;   Impulsive Behavior
    Interventions:   Drug: Tolcapone;   Drug: Placebo
    Sponsor:   University of California, San Francisco
    Recruiting
  • [C-11]PiB PET Imaging in Alcohol Use Disorders

    Condition:   Alcohol Use Disorder
    Interventions:   Radiation: [C-11];   Drug: Pittsburgh Compound B
    Sponsors:   University of Pittsburgh;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Brief Online Interventions for Alcohol Use

    Condition:   Alcohol Use Disorder
    Interventions:   Behavioral: Normative Feedback;   Behavioral: Inhibitory Control Training;   Behavioral: Working Memory Training
    Sponsors:   Craig Rush;   National Institute on Drug Abuse (NIDA)
    Recruiting
  • [C-11]NOP-1A and Alcohol Use Disorder

    Condition:   Alcohol Use Disorder
    Interventions:   Radiation: [C-11];   Drug: NOP-1A
    Sponsors:   Rajesh Narendran;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Project RAD: A Brief Intervention for Young Adult Alcohol or Marijuana Users

    Conditions:   Alcohol; Use, Problem;   Marijuana Usage
    Interventions:   Behavioral: Narrative Based Therapuetic Assessment (NbTa);   Behavioral: Health Education Control Condition (HE)
    Sponsor:   University of Houston
    Not yet recruiting
  • Alcohol Brief Intervention Plus Personalized Mobile Chat-based Intervention to Reduce Alcohol Misuse in an Emergency Department

    Condition:   Alcohol Use Disorder
    Interventions:   Behavioral: Mobile chat-based instant messages;   Behavioral: Alcohol brief intervention
    Sponsors:   The University of Hong Kong;   Queen Mary Hospital, Hong Kong
    Not yet recruiting
  • A Study of Parent and Child Emotions in Fetal Alcohol Spectrum Disorder (FASD)

    Condition:   Fetal Alcohol Spectrum Disorders
    Intervention:   Behavioral: Tuning In to kids intervention
    Sponsors:   University of Rochester;   National Institutes of Health (NIH)
    Recruiting
  • Topiramate and Prolonged Exposure

    Condition:   PTSD and Alcohol Use Disorder
    Interventions:   Drug: topiramate;   Behavioral: prolonged exposure;   Drug: placebo
    Sponsors:   VA Office of Research and Development;   University of California, San Diego
    Recruiting
  • Neural Mechanisms of Disulfiram Effects

    Condition:   Alcohol Use Disorder
    Intervention:   Drug: Disulfiram
    Sponsor:   New York State Psychiatric Institute
    Recruiting
  • Impulsivity and Alcohol Response

    Conditions:   Alcohol Use Disorder (AUD);   Subjective Response to Alcohol (SR)
    Interventions:   Drug: Alcohol;   Other: Placebo
    Sponsors:   University of Florida;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Ibudilast and Withdrawal-Related Dysphoria

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Ibudilast;   Other: Placebo
    Sponsor:   University of California, Los Angeles
    Recruiting
  • Alcohol Withdrawal Syndrome Treated With Adjunctive Phenobarbital or Ketamine

    Condition:   Alcohol Withdrawal Syndrome
    Interventions:   Drug: Ketamine;   Drug: Phenobarbital;   Drug: Lorazepam;   Drug: Placebo A;   Drug: Placebo B
    Sponsor:   Santa Barbara Cottage Hospital
    Not yet recruiting
  • A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder

    Conditions:   Healthy Volunteers;   Alcohol Drinking Related Problems;   Alcohol-Related Disorders
    Intervention:  
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH

    Conditions:   Alcohol Use Disorder;   Alcoholic Hepatitis
    Intervention:   Behavioral: Integrated AUD Treatment
    Sponsors:   Johns Hopkins University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Mifepristone Treatment of Alcohol Use Disorder

    Conditions:   Alcohol Dependence;   Alcohol Use Disorders;   Alcohol Abuse;   Alcoholism
    Interventions:   Drug: Mifepristone 1200 mg daily;   Behavioral: Standardized behavioral therapy;   Drug: Mifepristone 600 mg daily;   Drug: Placebo
    Sponsors:   The Scripps Research Institute;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Skills-training for Reducing Risky Alcohol Use in App Form

    Conditions:   Alcohol Abuse;   Alcohol Use Disorder;   Alcohol Drinking;   Alcohol Dependence;   Alcohol; Harmful Use
    Interventions:   Behavioral: Telecoach;   Behavioral: TeleCoach control
    Sponsor:   Karolinska Institutet
    Recruiting
  • Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)

    Conditions:   Alcohol Use Disorder;   Couples
    Interventions:   Combination Product: Oxytocin & Therapy;   Combination Product: Placebo & Therapy
    Sponsors:   Medical University of South Carolina;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • A Controlled Trial of Topiramate Treatment for Alcohol Dependence in Veterans With PTSD

    Conditions:   Alcohol Dependence;   Posttraumatic Stress Disorder (PTSD)
    Interventions:   Drug: Topiramate;   Drug: placebo
    Sponsors:   University of California, San Francisco;   United States Department of Defense;   San Francisco Veterans Affairs Medical Center;   Northern California Institute of Research and Education
    Recruiting
  • Evaluating "Signs of Safety": A Deaf-Accessible Therapy Toolkit for Alcohol Use Disorder and Trauma

    Conditions:   Alcohol Use Disorder;   Post Traumatic Stress Disorder
    Intervention:   Behavioral: Seeking Safety + Signs of Safety toolkit
    Sponsors:   University of Massachusetts, Worcester;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Mechanistic Evaluation of Guanfacine on Drinking Behavior

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Guanfacine ER;   Other: Placebo
    Sponsors:   Yale University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD

    Conditions:   Post Traumatic Stress Disorder;   Alcohol Use Disorder
    Interventions:   Drug: Topiramate;   Other: Placebo
    Sponsor:   New York University School of Medicine
    Not yet recruiting
  • CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use Disorders

    Conditions:   Posttraumatic Stress Disorder;   Alcohol Use Disorders
    Interventions:   Drug: doxazosin;   Drug: placebo
    Sponsors:   VA Office of Research and Development;   Medical University of South Carolina;   Consortium to Alleviate PTSD
    Recruiting
  • Lifestyle Physical Activity Intervention for Depressed Alcohol Dependent Women

    Condition:   Alcohol Dependence
    Interventions:   Behavioral: LPA+Fitbit;   Behavioral: HEC
    Sponsors:   Butler Hospital;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Aripiprazole for Bipolar Disorder and Alcohol Use Disorder

    Conditions:   Bipolar Disorder;   Alcoholism;   Alcohol Abuse
    Interventions:   Drug: Aripiprazole;   Drug: Placebo
    Sponsor:   University of Texas Southwestern Medical Center
    Recruiting
  • Technological Intervention for Reducing Alcohol Use Among People Living With HIV/AIDS

    Conditions:   Acquired Immunodeficiency Syndrome;   HIV/AIDS;   Alcohol Drinking
    Intervention:   Behavioral: Project TRAC: Tracking and Reducing Alcohol Consumption
    Sponsors:   University of Georgia;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Medication Development for Opioid and Alcohol Abuse

    Conditions:   Opioid-use Disorder;   Alcohol Use Disorder
    Intervention:   Drug: Gabapentin
    Sponsor:   New York State Psychiatric Institute
    Recruiting
  • CBT-I on Alcohol Treatment Outcomes Among Veterans

    Conditions:   Insomnia;   Alcohol Use Disorder
    Interventions:   Behavioral: Cognitive Behavioral Therapy for Insomnia;   Behavioral: Sleep Hygiene Education;   Behavioral: Cognitive Behavioral Therapy for Alcohol Use Disorders
    Sponsors:   University of Missouri-Columbia;   VA Office of Research and Development
    Not yet recruiting
  • Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

    Conditions:   Major Depressive Disorder;   Alcohol Use Disorder
    Interventions:   Drug: Ketamine + Naltrexone;   Drug: Ketamine + Placebo;   Drug: Placebo (psychoactive placebo midazolam) + Placebo
    Sponsor:   VA Office of Research and Development
    Recruiting
  • Cognitive Training in the Treatment of AUD

    Condition:   Alcohol Use Disorder Cognitive Decline
    Intervention:   Behavioral: Cognitive Remediation Training
    Sponsor:   VA Office of Research and Development
    Recruiting
  • Allogeneic HUman Mesenchymal Stem Cell InfusioN Versus Placebo in Subjects With Alcohol Use Disorder and Major DepreSsion.

    Conditions:   Major Depression;   Alcohol Use Disorder
    Interventions:   Drug: allogeneic human mesenchymal stem cells (allo-hMSCs);   Drug: Placebo
    Sponsors:   Joshua M Hare;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Alcohol Research Consortium in HIV-Intervention Research Arm

    Conditions:   HIV Positive;   Alcohol Use
    Interventions:   Behavioral: Computerized Brief Intervention (CBI);   Behavioral: CBT4CBT;   Drug: Recommendation and Counseling for Alcohol Pharmacotherapy
    Sponsor:   University of Alabama at Birmingham
    Recruiting
  • Does Guanfacine Attenuate Stress-Induced Drinking?

    Condition:   Alcohol Drinking
    Interventions:   Drug: Guanfacine 3mg/day;   Drug: Guanfacine 1.5mg/day;   Drug: Placebo
    Sponsors:   Yale University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Intermittent Theta Burst for the Treatment of Alcohol Use Disorders in Veterans

    Conditions:   Alcohol Use Disorder;   Depressive Disorder;   Cigarette Smoking
    Intervention:   Device: Intermittent theta burst transcranial magnetic stimulation
    Sponsor:   Stanford University
    Recruiting
  • Perceptions of Male Soldiers on Sex, Dating, and Alcohol-Use at Fort Bragg

    Conditions:   Sexual Assault and Rape;   Risk Behavior;   Alcohol Abuse
    Interventions:   Other: Social Norms Questionnaire;   Other: Standardized Interview;   Other: Group Discussion
    Sponsors:   Womack Army Medical Center;   Rhode Island Hospital;   University of North Carolina, Charlotte
    Recruiting
  • Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder

    Conditions:   Alcohol Use Disorder;   PTSD;   Cognitive Dysfunction
    Interventions:   Behavioral: Cognitive Training;   Behavioral: Cognitive training placebo control
    Sponsor:   VA Office of Research and Development
    Recruiting
  • Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological Treatment for Alcohol Use Disorder

    Conditions:   Alcohol Use Disorder;   Alcohol Abuse;   Alcohol Drinking;   Alcohol Dependence
    Interventions:   Behavioral: Cognitive Behavior Therapy;   Behavioral: Mindfulness Based Relapse Prevention
    Sponsors:   University of New Mexico;   The Mind Research Network
    Recruiting
  • Alcohol Screening & Brief Lntervention in Juvenile Justice: Filling the Gap

    Conditions:   Evaluating NIAAA's Alcohol Screener;   Evaluating a Brief Intervention
    Interventions:   Behavioral: Brief Intervention;   Behavioral: Brief Intervention with Coaching;   Behavioral: Treatment as Usual
    Sponsors:   University of Rhode Island;   Brown University
    Recruiting
  • Does Propanolol, a Beta Blocker, Attenuate Stress-Induced Drinking?

    Condition:   Alcohol Drinking
    Interventions:   Drug: Propanolol;   Drug: Placebo
    Sponsors:   Yale University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Smartphone Technology: Young Adult Drinking

    Conditions:   Alcohol Use;   Alcohol Drinking;   Drinking Behavior
    Interventions:   Other: Smartphone breathalyzer device/app use;   Other: BAC estimator app use;   Other: Text messaging procedure
    Sponsors:   University of Florida;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT)

    Conditions:   Tuberculosis;   HIV/AIDS;   Alcohol Abuse
    Interventions:   Drug: Isoniazid 300 Mg ORAL TABLET;   Drug: Pyridoxine 25 Mg Oral Tablet
    Sponsors:   University of California, San Francisco;   Boston University;   Boston Medical Center;   Mbarara University of Science and Technology
    Recruiting
  • Multimodal Sleep Intervention Using Wearable Technology

    Condition:   Drinking, Alcohol
    Interventions:   Behavioral: Advice;   Behavioral: Self-monitoring;   Behavioral: Feedback
    Sponsors:   Yale University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Computer-based Intervention for Alcohol-using HIV/HCV+ Women

    Conditions:   Human Immunodeficiency Virus;   Hepatitis C;   Alcohol Abuse
    Interventions:   Behavioral: Computer-based alcohol reduction intervention;   Behavioral: Standard-of-care
    Sponsors:   Emory University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • The Development of a Personalized, Real-time Intervention

    Condition:   Drinking, Alcohol
    Intervention:   Behavioral: PFIcope+EMI
    Sponsor:   Butler Hospital
    Recruiting
  • Brief Restructuring Intervention Following Trauma Exposure

    Conditions:   Posttraumatic Stress Disorder;   Alcohol Use Disorders
    Intervention:   Behavioral: Brief Cognitive Therapy
    Sponsors:   University of Washington;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Primary Care Treatment Integrating Motivation and Exposure

    Conditions:   Stress Disorders, Post-Traumatic;   Alcohol-Related Disorders
    Intervention:   Behavioral: PC-TIME
    Sponsors:   Syracuse VA Medical Center;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Zonisamide Outpatient Study

    Conditions:   Post Traumatic Stress Disorder;   Alcohol Use Disorder
    Interventions:   Drug: Zonisamide;   Drug: Placebo Comparator
    Sponsors:   Pharmacotherapies for Alcohol and Substance Abuse Consortium;   Congressionally Directed Medical Research Programs;   Michael Debakey Veterans Affairs Medical Center;   Baylor College of Medicine
    Not yet recruiting
  • Stress Reactivity as a Determinant in Co-occurring Alcohol Use and Anxiety Disorder: Diagnosis and Alcohol Use Outcomes

    Conditions:   Alcohol Use Disorder;   Anxiety Disorder/Anxiety State;   Stress Disorder;   Hypothalamic Pituitary Adrenal;   Drinking to Cope
    Intervention:  
    Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • The HOLIDAY (HOw ALcohol InDuces Atrial TachYarrhythmias) Study

    Conditions:   Atrial Fibrillation;   Alcohol
    Interventions:   Drug: Ethanol;   Drug: Placebo
    Sponsor:   University of California, San Francisco
    Recruiting
  • Individualizing Incentives for Alcohol in the Severely Mentally Ill

    Conditions:   Schizophrenia;   Bipolar Disorder;   Major Depressive Disorder;   Alcohol Dependence
    Interventions:   Behavioral: Usual CM;   Behavioral: High-Magnitude CM;   Behavioral: Shaping CM
    Sponsors:   Washington State University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Dietary Fiber Intake in Alcohol-dependent Patients

    Condition:   Alcoholism
    Interventions:   Dietary Supplement: inulin;   Dietary Supplement: placebo
    Sponsor:   Université Catholique de Louvain
    Recruiting
  • Alcohol Monitor Validation

    Condition:   Human Immunodeficiency Virus (HIV)
    Interventions:   Device: Skyn Monitor Lab Session 1;   Device: Skyn Monitor Field Test with EMA App;   Device: Skyn Monitor Lab Session 2
    Sponsors:   University of Florida;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • e-Health Coping Skills Training for Women Whose Partner Has a Drinking Problem

    Condition:   Alcohol Abuse
    Interventions:   Behavioral: eHealth Coping Skills Training;   Behavioral: eHealth Usual Web Care;   Behavioral: Coach Support
    Sponsors:   State University of New York at Buffalo;   University of Oregon
    Not yet recruiting
  • NCARE, Transition to Recovery

    Conditions:   Alcohol Withdrawal;   Substance Use Disorders
    Interventions:   Behavioral: Patient navigation;   Behavioral: Motivational interviewing (MI)
    Sponsor:   University of Colorado, Denver
    Not yet recruiting
  • Scaling Up Science-based Mental Health Interventions in Latin America

    Conditions:   Depression;   Problematic Alcohol Use
    Intervention:   Behavioral: Laddr
    Sponsors:   Dartmouth-Hitchcock Medical Center;   Pontificia Universidad Javeriana;   National Institute of Mental Health (NIMH)
    Recruiting
  • Messaging Interventions to Reduce Alcohol Problems Project

    Conditions:   Alcohol-Related Disorders;   Alcohol Use Disorders;   Alcohol Drinking;   Alcoholism;   Alcohol Abuse
    Interventions:   Behavioral: Drink Tracking (MA);   Behavioral: Adaptive Tailored (TA);   Behavioral: Tailored (TO)
    Sponsors:   Partnership for Drug-Free Kids;   Feinstein Institute for Medical Research
    Not yet recruiting
  • Behavioral and Functional MRI Task Development, Implementation, and Testing

    Conditions:   Alcohol Dependence;   Alcohol Drinking;   Alcoholism
    Intervention:  
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Brief New Treatment for Suicide Attempts

    Conditions:   Suicide, Attempted;   Drug Use;   Alcohol; Use, Problem
    Interventions:   Behavioral: Brief intervention to prevent suicide attempt;   Behavioral: Enhanced treatment as usual
    Sponsors:   University of Rochester;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • MI With Text Messaging to Reduce Sexual Risk and Hazardous Drinking Among MSM

    Conditions:   Alcohol; Harmful Use;   Sex, Unsafe
    Intervention:   Behavioral: MI&TXT4MSM
    Sponsors:   Boston University Charles River Campus;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • The Role of Neural Systems for Emotion Regulation in Coping With Alcohol Craving

    Condition:   Alcoholism
    Intervention:   Behavioral: Cognitive Behavioral Coping Skills Therapy
    Sponsor:   New York State Psychiatric Institute
    Recruiting
  • Psychobiology of Stress and Alcohol Craving

    Conditions:   Alcohol Use Disorder;   Stress Reaction;   Social Stress;   Craving;   Behavior
    Interventions:   Behavioral: Trier Social Stress Test;   Behavioral: Reading Newspaper;   Behavioral: Barlab-Exposure
    Sponsors:   Central Institute of Mental Health, Mannheim;   Project Group for Automation in Medicine and Biotechnology PAMB, Mannheim
    Recruiting
  • Oxytocin in Alcohol Use Disorder

    Condition:   Alcoholism
    Interventions:   Drug: Oxytocin;   Other: Placebo
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Medication Development in Alcoholism: Apremilast Versus Placebo

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Apremilast;   Drug: Placebo
    Sponsors:   The Scripps Research Institute;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • A Community-Based Strategy for Preventing Underage Drinking

    Condition:   Alcohol Abuse
    Intervention:   Behavioral: Youth Access
    Sponsor:   Oregon Research Institute
    Recruiting
  • Alcohol and Bariatric Surgery

    Condition:   Obesity
    Interventions:   Other: Oral Alcohol challenge test Alcohol visit first;   Other: Oral Alcohol challenge test Placebo visit first;   Other: Intravenous Alcohol Challenge Test (Clamp);   Other: Intravenous Alcohol Self-administration Test
    Sponsors:   University of Illinois at Urbana-Champaign;   Carle Foundation Hospital
    Recruiting
  • Impact of Meal Composition and Alcohol Consumption on Postprandial Glycemic Control in Subjects With Type 1 Diabetes

    Condition:   Diabetes Mellitus, Type 1
    Intervention:   Other: Mixed meal with different macronutrient composition
    Sponsors:   Jorge Bondia;   Hospital Francesc de Borja, Gandia, Spain;   Ministerio de Economía y Competitividad, Spain
    Recruiting
  • Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICU

    Condition:   Alcoholism
    Interventions:   Drug: BACLOFEN;   Drug: PLACEBO
    Sponsor:   Nantes University Hospital
    Recruiting
  • Impact of Marketing of Alcohol Products on Young People

    Condition:   Alcoholism
    Interventions:   Device: MRI;   Behavioral: Alcohol Use Disorders Identification Test
    Sponsors:   Rennes University Hospital;   Ecole des Hautes Etudes en Santé Publique (EHESP)
    Recruiting
  • Imaging Biomarker for Addiction Treatment Outcome

    Conditions:   Opioid-Related Disorders;   Alcohol-Related Disorders
    Intervention:  
    Sponsor:   National Institute on Drug Abuse (NIDA)
    Not yet recruiting
  • Alcohol Impaired Driving: From the Laboratory to the Natural Environment

    Condition:   Drinking and Driving
    Interventions:   Behavioral: BAC feedback/warning;   Behavioral: No BAC feedback/warning
    Sponsors:   University of Missouri-Columbia;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Modulating the Impact of Critical Events in Early HIV Infection: Effect of ART Initiation and Alcohol Use

    Condition:   HIV Infection
    Interventions:   Drug: ART initiation at time of HIV diagnosis;   Drug: ART at 24 weeks
    Sponsors:   Fred Hutchinson Cancer Research Center;   University of California, San Francisco;   University of Washington;   Asociación Civil Impacta Salud y Educación, Peru;   Université de Montréal;   Seattle Children's Hospital
    Recruiting
  • Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder Via Microbiota Investigations: A Pilot Study

    Condition:   Alcoholism
    Intervention:  
    Sponsors:   National Institute on Alcohol Abuse and Alcoholism (NIAAA);   National Institute on Drug Abuse (NIDA);   The Peter G. Dodge Foundation (PGDF)
    Recruiting
  • Virtual Reality- Working Memory Retraining

    Conditions:   Alcohol Use Disorder;   Mild Traumatic Brain Injury
    Interventions:   Behavioral: VR-WMR-Only;   Behavioral: Exercise-only;   Behavioral: Active VR-WMR
    Sponsors:   University of California, San Francisco;   San Francisco VA Health Care System
    Not yet recruiting
  • Pharmacogenomics and Pharmacometabolomics of Acamprosate Treatment Outcome

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Acamprosate;   Other: Placebo
    Sponsors:   Mayo Clinic;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Treatment Parameters for the Empower Neuromodulation System (ENS)

    Condition:   Alcohol Use Disorder
    Intervention:   Device: TENS
    Sponsor:   Theranova, L.L.C.
    Recruiting
  • Effect of CBT Microinterventions on Mechanisms of Behavior Change Among Adults With AUD

    Condition:   Alcohol Use Disorder
    Interventions:   Behavioral: Control;   Behavioral: Functional Analysis;   Behavioral: Cognitive Restructuring;   Behavioral: Dealing With Cravings
    Sponsors:   University of Massachusetts, Worcester;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Sex Differences, Cognitive Training & Emotion Processing

    Condition:   Alcohol Use Disorder
    Interventions:   Other: Affective Training;   Other: Neutral Training
    Sponsors:   University of Florida;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Preventing Risky Drinking in Veterans Treated With Prescription Opioids

    Conditions:   Pain;   Opiates;   Alcohol Drinking
    Interventions:   Behavioral: Prevention Intervention;   Behavioral: Brief Intervention
    Sponsors:   University of Pennsylvania;   United States Department of Defense;   Corporal Michael J. Crescenz VA Medical Center;   Medical University of South Carolina;   VA Pittsburgh Healthcare System
    Recruiting
  • Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive Control

    Condition:   Alcohol Use Disorder
    Interventions:   Drug: Tolcapone;   Drug: Placebo
    Sponsors:   Medical University of South Carolina;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Say When: Targeting Heavy Alcohol Use With Naltrexone Among MSM

    Conditions:   Binge Drinking;   HIV
    Interventions:   Drug: Placebo;   Drug: Naltrexone
    Sponsors:   University of California, San Francisco;   San Francisco Department of Public Health;   National Institutes of Health (NIH)
    Recruiting
  • Combined Alcohol and Cannabis Effects on Skills of Young Drivers

    Condition:   Psychomotor Impairment
    Interventions:   Drug: delta 9 tetrahydrocannabinol;   Drug: placebo delta 9 tetrahydrocannabinol;   Drug: Alcohol;   Drug: Placebo alcohol
    Sponsors:   Centre for Addiction and Mental Health;   Canadian Institutes of Health Research (CIHR);   Health Canada
    Recruiting
  • Impairing Drugs and Alcohol as Risk Factors for Traumatic Injuries

    Condition:   Trauma Injury
    Intervention:  
    Sponsors:   Oslo University Hospital;   University of Oslo;   Norwegian National Trauma Registry;   Norwegian National Advisory Unit on Trauma;   Norwegian Public Roads Administration;   Norwegian Directorate of Health;   Norwegian Ministry of Transport and Communications;   Sykehuset Innlandet HF
    Not yet recruiting
  • Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

    Conditions:   Alcohol Dependence;   Alcohol Drinking;   Alcohol-Related Disorders;   Alcoholism;   Brain Mapping
    Intervention:  
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline

    Conditions:   Cesarean Section; Infection;   Surgical Site Infection
    Interventions:   Drug: Chlorhexidine-alcohol;   Drug: Povidine-iodine;   Drug: Sterile saline
    Sponsor:   Columbia University
    Recruiting
  • PVP Iodine vs Chlorhexidine in Alcohol for Disinfection of the Surgical Site

    Condition:   Surgical Site Infections
    Interventions:   Drug: CHX disinfection;   Drug: PI Disinfection
    Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation
    Recruiting
  • Swift, Certain, and Fair: Reducing Recidivism and Improving Outcomes for Alcohol and Drug Users on State Parole

    Conditions:   Substance Abuse;   Criminal Behavior
    Interventions:   Behavioral: SCF Supervision with Secure Confinement Sanctioning;   Behavioral: SCF Supervision with Work Release Sanctioning;   Behavioral: SCF Supervision with GPS Supervision Sanctioning
    Sponsors:   Botec Analysis, LLC;   Pennsylvania Department of Corrections;   Bureau of Justice Assistance
    Not yet recruiting
  • Treatment of Asian Flushing Syndrome With Topical Alpha Agonists

    Conditions:   Flushing;   Alcohol-Related Disorders;   Aldehyde Dehydrogenase Deficiency
    Interventions:   Drug: Brimonidine Tartrate;   Drug: Placebo Vehicle Gel
    Sponsor:   University of California, San Francisco
    Recruiting
  • Chlorhexidine-Alcohol Versus Povidone Iodine-Alcohol, Combined or Not With Use of a Bundle of New Devices, for Prevention of Intravascular-catheter Colonization and Catheter Failure

    Conditions:   Intravascular-catheter Colonization;   Catheter Failure
    Interventions:   Drug: Povidone-Iodine-Alcohol;   Drug: Chlorhexidine-Alcohol;   Device: Insyte Autoguard BC Winged;   Device: Nexiva single port catheter, MaxZero needless connector, PureHub Deinfecting Caps and Posiflush prefilled saline syringes
    Sponsor:   Poitiers University Hospital
    Recruiting
  • Using Imaging to Assess Effects of THC on Brain Activity

    Conditions:   Intoxication Alcohol;   Intoxication THC;   Intoxication Combined Alcohol THC
    Interventions:   Drug: Dronabinol;   Drug: Ethanol;   Drug: Placebo Dronabinol;   Drug: Placebo Ethanol
    Sponsors:   Massachusetts General Hospital;   National Institute on Drug Abuse (NIDA)
    Recruiting
  • The Insomnia Treatment and Problems Study for Veterans

    Conditions:   Insomnia;   Alcohol; Harmful Use
    Interventions:   Behavioral: Cognitive Behavioral Therapy for Insomnia;   Behavioral: Sleep Hygeine
    Sponsors:   University of Missouri-Columbia;   American Academy of Sleep Medicine
    Not yet recruiting
  • Insomnia Treatment and Problems (the iTAP Study)

    Conditions:   Insomnia;   Alcohol; Harmful Use
    Interventions:   Behavioral: Cognitive Behavioral Therapy for Insomnia (CBT-I);   Behavioral: Sleep Hygiene
    Sponsor:   University of Missouri-Columbia
    Recruiting
  • Adverse Childhood Experiences in Substance-related Disorders

    Conditions:   Alcohol Use Disorder;   Trauma, Psychological
    Intervention:   Other: No intervention
    Sponsors:   Central Institute of Mental Health, Mannheim;   German Research Foundation
    Recruiting
  • Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD

    Conditions:   PTSD;   Alcohol Use Disorder
    Interventions:   Drug: Pregabalin plus BBCET;   Other: Placebo plus BBCET
    Sponsors:   University of Maryland;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Understanding Longitudinal Clinical Outcomes and Post-release Retention in Care Among HIV-infected Prisoners in Lusaka, Zambia

    Conditions:   HIV;   Alcohol Use Disorders
    Intervention:   Other: Transitional HIV care for prison releasees
    Sponsors:   University of North Carolina, Chapel Hill;   National Institutes of Health (NIH);   John E. Fogarty International Center (FIC)
    Recruiting
  • Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III

    Conditions:   Cannabis;   Alcohol Effect;   Driving Under the Influence of Alcohol and Other Drugs
    Interventions:   Drug: Active Dronabinol;   Drug: Placebo;   Drug: Active Ethanol
    Sponsor:   Yale University
    Recruiting
  • Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I

    Conditions:   Cannabis;   Alcohol Effect;   Driving Under the Influence of Alcohol and Other Drugs
    Interventions:   Drug: Active inhaled delta-9-THC;   Drug: Placebo;   Drug: Active Oral Ethanol
    Sponsor:   Yale University
    Recruiting
  • Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

    Conditions:   Cannabis;   Alcohol Effect;   Driving Under the Influence of Alcohol and Other Drugs
    Interventions:   Drug: Active delta-9-THC;   Drug: Placebo;   Drug: Active Ethanol
    Sponsor:   Yale University
    Recruiting
  • Evaluating Interventions for Alcohol Use Disorder

    Condition:   Alcoholism
    Interventions:   Behavioral: Motivational Enhancement Therapy;   Behavioral: Cognitive Behavioral Therapy;   Other: FC Assessment;   Other: IB Assessment
    Sponsors:   Rutgers, The State University of New Jersey;   Syracuse University;   Pacific Institute for Research and Evaluation;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Marijuana Effects on Simulated Driving Performance

    Conditions:   Cannabis;   Cannabis Use;   Marijuana;   Marijuana Usage;   Alcohol Drinking
    Interventions:   Drug: Marijuana;   Drug: Alcohol
    Sponsor:   Shanna Babalonis, PhD
    Not yet recruiting
  • Technology-Based Intervention for Reducing Sexually Transmitted Infections and Substance Use During Pregnancy

    Conditions:   Sexually Transmitted Infection;   Alcohol Use Complicating the Puerperium;   Alcohol Use Complicating Pregnancy, Unspecified Trimester;   Drug Use
    Interventions:   Behavioral: Health Check-up for Expectant Moms;   Behavioral: Information-matched control
    Sponsors:   University of Michigan;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Not yet recruiting
  • NAC for Treating Comorbid PTSD and SUD

    Conditions:   Posttraumatic Stress Disorder (PTSD);   Alcohol Use Disorder (AUD);   Substance Use Disorder (SUD)
    Interventions:   Drug: N-acetylcysteine;   Drug: Placebo;   Behavioral: Cognitive behavioral therapy
    Sponsors:   Medical University of South Carolina;   United States Department of Defense;   Institute for Translational Neuroscience
    Recruiting
  • Development and Testing of a Just-in-Time Adaptive Smart Phone Intervention to Reduce Drinking Among Homeless Adults

    Conditions:   Alcohol Use Disorder;   Treatment;   Homelessness
    Intervention:   Behavioral: EMA + App/Treatment Messages
    Sponsors:   University of North Texas Health Science Center;   University of Oklahoma
    Recruiting
  • VRT as a Biomarker of Cerebellar Dysfunction in Chronic Cannabis Use

    Conditions:   Cannabis Use;   Alcohol Use Disorder;   Healthy
    Intervention:   Diagnostic Test: Visuomotor adaptation task
    Sponsor:   Hospital Clinic of Barcelona
    Not yet recruiting
  • Effectiveness of Group Focused Psychosocial Support for Adults Affected by Humanitarian Crises

    Conditions:   Depression;   Posttraumatic Stress Disorder;   Alcohol Use Disorder
    Interventions:   Behavioral: Group problem management plus;   Behavioral: Enhanced treatment as usual
    Sponsors:   George Washington University;   World Health Organization;   Transcultural Psychosocial Organization Nepal;   Duke University;   King's College London
    Recruiting
  • Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

    Conditions:   Social Skills;   Self-Criticism;   Post-traumatic Stress Disorder;   Depression;   Alcohol Abuse;   Drinking, College;   Alcohol Drinking;   Alcohol; Harmful Use;   Social Stigma;   Social Norms;   Social Responsibility;   Social Behavior;   Empathy;   Coping Skills;   Coping Behavior
    Intervention:   Behavioral: Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
    Sponsors:   University of New Hampshire;   University of Illinois at Chicago;   University of South Florida;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Understanding and Intervening With Heavy Drinking Among Patients With HIV and HCV

    Conditions:   Alcohol Use Disorder;   HIV/AIDS;   Hepatitis C;   Binge Drinking
    Intervention:   Behavioral: Intervention: (Clinician's Guide + HealthCall for HIV/HCV)
    Sponsors:   New York State Psychiatric Institute;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Substance Abuse Pre-Treatment Screening Study

    Conditions:   Cocaine Abuse;   Cocaine Dependence;   Opiate Dependence;   Alcohol Dependence;   Substance Abuse
    Interventions:   Drug: modafinil;   Drug: d-amphetamine;   Drug: L-Dopa;   Drug: Naltrexone
    Sponsors:   The University of Texas Health Science Center, Houston;   National Institute on Drug Abuse (NIDA)
    Recruiting
  • CT-guided Ablation of the Ganglion Impar for Pelvic Tumors: Comparethe Addition of Ketorolac or Dexamethasone

    Condition:   Pain, Chronic
    Intervention:   Procedure: ganglion impar block
    Sponsor:   Mansoura University
    Recruiting
  • BA Trial for Co-Occurring Depression and Substance Use

    Conditions:   Depression;   Substance Use Disorders
    Interventions:   Behavioral: Behavioural Activation;   Behavioral: Treatment as Usual
    Sponsors:   University of Sheffield;   University of North Carolina, Chapel Hill
    Recruiting
  • ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings

    Condition:   Hepatitis C
    Intervention:   Procedure: Campaign days
    Sponsors:   Kirby Institute;   National Health and Medical Research Council, Australia
    Recruiting
  • Collaborative and Stepped Care in Mental Health (COMET)

    Conditions:   Depressive Disorder;   Anxiety Disorder;   Somatoform Disorder;   Alcohol Use Disorder
    Intervention:   Other: collaborative and stepped care model
    Sponsors:   Universitätsklinikum Hamburg-Eppendorf;   Center for Health Care Research Hamburg;   Hamburg Center for Health Economics
    Recruiting
  • Substance Use Interventions for Truant Adolescents

    Conditions:   Adolescent Problem Behavior;   Truancy; Unsocialized;   Marijuana Abuse;   Truancy; Socialized;   Substance Abuse;   Alcohol Abuse
    Interventions:   Behavioral: Motivational + Family Check-up (MET+FCU);   Other: Psychoeducation
    Sponsors:   Brown University;   National Institute on Drug Abuse (NIDA)
    Recruiting
  • Nottingham Community Liver Biomarkers Cohort

    Conditions:   Chronic Liver Disease;   Alcohol Use Disorder;   Type 2 Diabetes;   Persistently Elevated ALT;   Obesity
    Intervention:   Device: Fibrosis Biomarkers
    Sponsor:   University of Nottingham
    Recruiting
  • Immune Cell Dysfunction in Severe Alcoholic Hepatitis

    Condition:   Hepatitis
    Intervention:  
    Sponsor:   Basildon and Thurrock University Hospitals NHS Foundation Trust
    Recruiting
  • Unit and Clinic Evaluation, Screening, Assessment, and Management

    Condition:   Alcoholism
    Intervention:  
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • A Novel Compound for Alcoholism Treatment: A Translational Strategy

    Condition:   Alcoholism
    Interventions:   Drug: PF-05190457;   Behavioral: MI-VF;   Other: Placebo;   Other: Counseling
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Brief Intervention by Community Health Workers for Unhealthy Drinking in Latinos

    Conditions:   Drinking Heavy;   Drinking Behavior;   Drinking Excessive
    Interventions:   Behavioral: Motivational Enhancement Therapy and Strengths Based Case Management (MET/SBCM);   Other: Alcohol education brochure
    Sponsors:   University of California, Los Angeles;   University of California, San Diego;   Providence Health & Services;   Northeastern University
    Recruiting
  • Computer-Assisted Self-Administration of Ethanol

    Condition:   Alcoholic Intoxication
    Intervention:   Drug: Alcohol
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • TARGET BP I Clinical Trial

    Condition:   Hypertension
    Interventions:   Drug: Dehydrated alcohol;   Device: Peregrine System Kit (Sham Procedure)
    Sponsor:   Ablative Solutions, Inc.
    Not yet recruiting
  • Trial of an Adapted STD Screening and Risk Reduction Intervention

    Conditions:   Alcohol Use;   Drug Use;   Diagnostic Self Evaluation;   Gonorrhea;   Unprotected Sex;   Chlamydia;   Trichomonas
    Interventions:   Behavioral: Project EMPWR;   Other: Optimized Standard Care (OSC)
    Sponsor:   Johns Hopkins Bloomberg School of Public Health
    Recruiting
  • Stress-related Predictor Profiles in Human Addiction

    Conditions:   Alcohol Use Disorder;   Stress Reaction;   Social Stress;   Craving;   Relapse;   Addiction;   Risk Behavior
    Interventions:   Behavioral: Trier Social Stress Test;   Behavioral: Ergometer;   Behavioral: Barlab-Exposure;   Behavioral: Reading Newspaper
    Sponsors:   Central Institute of Mental Health, Mannheim;   Project Group for Automation in Medicine and Biotechnology PAMB, Mannheim
    Not yet recruiting
  • Ibogaine in the Treatment of Alcoholism: a Randomized, Double-blind, Placebo-controlled, Escalating-dose, Phase 2 Trial

    Condition:   Alcoholism
    Intervention:   Drug: Ibogaine Hydrochloride
    Sponsors:   University of Sao Paulo;   Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.;   Conselho Nacional de Desenvolvimento Científico e Tecnológico
    Not yet recruiting
  • Ketogenic Diet (KD) in Alcoholism

    Condition:   Alcoholism
    Interventions:   Dietary Supplement: Ketogenic Diet (KD);   Dietary Supplement: Standard American (SA) Meals and Shakes
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • A Study of Pleiotropic Pioglitazone Effects on the Alcoholic Lung (APPEAL Study)

    Condition:   Alcoholism
    Intervention:   Drug: Pioglitazone
    Sponsors:   Emory University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

    Conditions:   Depression;   Alcoholism;   Drug Abuse
    Interventions:   Behavioral: Interpersonal and Social Rhythm Therapy (ISRT);   Behavioral: Bipolar-Specific Cognitive Behavioral Therapy (CBT);   Behavioral: Mindfulness-Based Stress Reduction (MBSR);   Behavioral: Psycho-education & Understanding Bipolar Medications Therapy
    Sponsor:   Emory University
    Recruiting
  • Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

    Conditions:   Rare Disorders;   Undiagnosed Disorders;   Disorders of Unknown Prevalence;   Cornelia De Lange Syndrome;   Prenatal Benign Hypophosphatasia;   Perinatal Lethal Hypophosphatasia;   Odontohypophosphatasia;   Adult Hypophosphatasia;   Childhood-onset Hypophosphatasia;   Infantile Hypophosphatasia;   Hypophosphatasia;   Kabuki Syndrome;   Bohring-Opitz Syndrome;   Narcolepsy Without Cataplexy;   Narcolepsy-cataplexy;   Hypersomnolence Disorder;   Idiopathic Hypersomnia Without Long Sleep Time;   Idiopathic Hypersomnia With Long Sleep Time;   Idiopathic Hypersomnia;   Kleine-Levin Syndrome;   Kawasaki Disease;   Leiomyosarcoma;   Leiomyosarcoma of the Corpus Uteri;   Leiomyosarcoma of the Cervix Uteri;   Leiomyosarcoma of Small Intestine;   Acquired Myasthenia Gravis;   Addison Disease;   Hyperacusis (Hyperacousis);   Juvenile Myasthenia Gravis;   Transient Neonatal Myasthenia Gravis;   Williams Syndrome;   Lyme Disease;   Myasthenia Gravis;   Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome);   Isolated Klippel-Feil Syndrome;   Frasier Syndrome;   Denys-Drash Syndrome;   Beckwith-Wiedemann Syndrome;   Emanuel Syndrome;   Isolated Aniridia;   Beckwith-Wiedemann Syndrome Due to Paternal Uniparental Disomy of Chromosome 11;   Beckwith-Wiedemann Syndrome Due to Imprinting Defect of 11p15;   Beckwith-Wiedemann Syndrome Due to 11p15 Translocation/Inversion;   Beckwith-Wiedemann Syndrome Due to 11p15 Microduplication;   Beckwith-Wiedemann Syndrome Due to 11p15 Microdeletion;   Axenfeld-Rieger Syndrome;   Aniridia-intellectual Disability Syndrome;   Aniridia - Renal Agenesis - Psychomotor Retardation;   Aniridia - Ptosis - Intellectual Disability - Familial Obesity;   Aniridia - Cerebellar Ataxia - Intellectual Disability;   Aniridia - Absent Patella;   Aniridia;   Peters Anomaly - Cataract;   Peters Anomaly;   Potocki-Shaffer Syndrome;   Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11;   Silver-Russell Syndrome Due to Imprinting Defect of 11p15;   Silver-Russell Syndrome Due to 11p15 Microduplication;   Syndromic Aniridia;   WAGR Syndrome;   Wolf-Hirschhorn Syndrome;   4p16.3 Microduplication Syndrome;   4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome;   Autosomal Recessive Stickler Syndrome;   Stickler Syndrome Type 2;   Stickler Syndrome Type 1;   Stickler Syndrome;   Mucolipidosis Type 4;   X-linked Spinocerebellar Ataxia Type 4;   X-linked Spinocerebellar Ataxia Type 3;   X-linked Intellectual Disability - Ataxia - Apraxia;   X-linked Progressive Cerebellar Ataxia;   X-linked Non Progressive Cerebellar Ataxia;   X-linked Cerebellar Ataxia;   Vitamin B12 Deficiency Ataxia;   Toxic Exposure Ataxia;   Unclassified Autosomal Dominant Spinocerebellar Ataxia;   Thyroid Antibody Ataxia;   Sporadic Adult-onset Ataxia of Unknown Etiology;   Spinocerebellar Ataxia With Oculomotor Anomaly;   Spinocerebellar Ataxia With Epilepsy;   Spinocerebellar Ataxia With Axonal Neuropathy Type 2;   Spinocerebellar Ataxia Type 8;   Spinocerebellar Ataxia Type 7;   Spinocerebellar Ataxia Type 6;   Spinocerebellar Ataxia Type 5;   Spinocerebellar Ataxia Type 4;   Spinocerebellar Ataxia Type 37;   Spinocerebellar Ataxia Type 36;   Spinocerebellar Ataxia Type 35;   Spinocerebellar Ataxia Type 34;   Spinocerebellar Ataxia Type 32;   Spinocerebellar Ataxia Type 31;   Spinocerebellar Ataxia Type 30;   Spinocerebellar Ataxia Type 3;   Spinocerebellar Ataxia Type 29;   Spinocerebellar Ataxia Type 28;   Spinocerebellar Ataxia Type 27;   Spinocerebellar Ataxia Type 26;   Spinocerebellar Ataxia Type 25;   Spinocerebellar Ataxia Type 23;   Spinocerebellar Ataxia Type 22;   Spinocerebellar Ataxia Type 21;   Spinocerebellar Ataxia Type 20;   Spinocerebellar Ataxia Type 2;   Spinocerebellar Ataxia Type 19/22;   Spinocerebellar Ataxia Type 18;   Spinocerebellar Ataxia Type 17;   Spinocerebellar Ataxia Type 16;   Spinocerebellar Ataxia Type 15/16;   Spinocerebellar Ataxia Type 14;   Spinocerebellar Ataxia Type 13;   Spinocerebellar Ataxia Type 12;   Spinocerebellar Ataxia Type 11;   Spinocerebellar Ataxia Type 10;   Spinocerebellar Ataxia Type 1 With Axonal Neuropathy;   Spinocerebellar Ataxia Type 1;   Spinocerebellar Ataxia - Unknown;   Spinocerebellar Ataxia - Dysmorphism;   Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature;   Spectrin-associated Autosomal Recessive Cerebellar Ataxia;   Spasticity-ataxia-gait Anomalies Syndrome;   Spastic Ataxia With Congenital Miosis;   Spastic Ataxia - Corneal Dystrophy;   Spastic Ataxia;   Rare Hereditary Ataxia;   Rare Ataxia;   Recessive Mitochondrial Ataxia Syndrome;   Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature;   Posterior Column Ataxia - Retinitis Pigmentosa;   Post-Stroke Ataxia;   Post-Head Injury Ataxia;   Post Vaccination Ataxia;   Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract;   Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus;   Non-progressive Cerebellar Ataxia With Intellectual Disability;   Non-hereditary Degenerative Ataxia;   Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity;   Olivopontocerebellar Atrophy - Deafness;   NARP Syndrome;   Myoclonus - Cerebellar Ataxia - Deafness;   Multiple System Atrophy, Parkinsonian Type;   Multiple System Atrophy, Cerebellar Type;   Multiple System Atrophy;   Maternally-inherited Leigh Syndrome;   Machado-Joseph Disease Type 3;   Machado-Joseph Disease Type 2;   Machado-Joseph Disease Type 1;   Lethal Ataxia With Deafness and Optic Atrophy;   Leigh Syndrome;   Leukoencephalopathy With Mild Cerebellar Ataxia and White Matter Edema;   Leukoencephalopathy - Ataxia - Hypodontia - Hypomyelination;   Leigh Syndrome With Nephrotic Syndrome;   Leigh Syndrome With Leukodystrophy;   Leigh Syndrome With Cardiomyopathy;   Late-onset Ataxia With Dementia;   Intellectual Disability-hyperkinetic Movement-truncal Ataxia Syndrome;   Infection or Post Infection Ataxia;   Infantile-onset Autosomal Recessive Nonprogressive Cerebellar Ataxia;   Infantile Onset Spinocerebellar Ataxia;   GAD Ataxia;   Hereditary Episodic Ataxia;   Gliadin/Gluten Ataxia;   Friedreich Ataxia;   Fragile X-associated Tremor/Ataxia Syndrome;   Familial Paroxysmal Ataxia;   Exposure to Medications Ataxia;   Episodic Ataxia With Slurred Speech;   Episodic Ataxia Unknown Type;   Episodic Ataxia Type 7;   Episodic Ataxia Type 6;   Episodic Ataxia Type 5;   Episodic Ataxia Type 4;   Episodic Ataxia Type 3;   Episodic Ataxia Type 1;   Epilepsy and/or Ataxia With Myoclonus as Major Feature;   Early-onset Spastic Ataxia-neuropathy Syndrome;   Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity;   Early-onset Cerebellar Ataxia With Retained Tendon Reflexes;   Early-onset Ataxia With Dementia;   Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia;   Dilated Cardiomyopathy With Ataxia;   Cataract - Ataxia - Deafness;   Cerebellar Ataxia, Cayman Type;   Cerebellar Ataxia With Peripheral Neuropathy;   Cerebellar Ataxia - Hypogonadism;   Cerebellar Ataxia - Ectodermal Dysplasia;   Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss;   Brain Tumor Ataxia;   Brachydactyly - Nystagmus - Cerebellar Ataxia;   Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia;   Autosomal Recessive Syndromic Cerebellar Ataxia;   Autosomal Recessive Spastic Ataxia With Leukoencephalopathy;   Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay;   Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria;   Autosomal Recessive Spastic Ataxia;   Autosomal Recessive Metabolic Cerebellar Ataxia;   Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine;   Autosomal Recessive Ataxia, Beauce Type;   Autosomal Recessive Ataxia Due to Ubiquinone Deficiency;   Autosomal Recessive Ataxia Due to PEX10 Deficiency;   Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia;   Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency;   Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency;   Autosomal Recessive Congenital Cerebellar Ataxia;   Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome;   Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency;   Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency;   Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency;   Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome;   Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity;   Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency;   Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect;   Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion;   Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation;   Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness;   Autosomal Recessive Cerebellar Ataxia;   Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly;   Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation;   Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy;   Autosomal Dominant Spastic Ataxia Type 1;   Autosomal Dominant Spastic Ataxia;   Autosomal Dominant Optic Atrophy;   Ataxia-telangiectasia Variant;   Ataxia-telangiectasia;   Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy;   Autosomal Dominant Cerebellar Ataxia Type 4;   Autosomal Dominant Cerebellar Ataxia Type 3;   Autosomal Dominant Cerebellar Ataxia Type 2;   Autosomal Dominant Cerebellar Ataxia Type 1;   Autosomal Dominant Cerebellar Ataxia;   Ataxia-telangiectasia-like Disorder;   Ataxia-intellectual Disability-oculomotor Apraxia-cerebellar Cysts Syndrome;   Ataxia-deafness-intellectual Disability Syndrome;   Ataxia With Vitamin E Deficiency;   Ataxia With Dementia;   Ataxia Neuropathy Spectrum;   Ataxia - Tapetoretinal Degeneration;   Ataxia - Photosensitivity - Short Stature;   Ataxia - Pancytopenia;   Ataxia - Oculomotor Apraxia Type 1;   Ataxia - Hypogonadism - Choroidal Dystrophy;   Ataxia - Other;   Ataxia - Genetic Diagnosis - Unknown;   Acquired Ataxia;   Adult-onset Autosomal Recessive Cerebellar Ataxia;   Alcohol Related Ataxia;   Multiple Endocrine Neoplasia;   Multiple Endocrine Neoplasia Type II;   Multiple Endocrine Neoplasia Type 1;   Multiple Endocrine Neoplasia Type 2;   Multiple Endocrine Neoplasia, Type IV;   Multiple Endocrine Neoplasia, Type 3;   Multiple Endocrine Neoplasia (MEN) Syndrome;   Multiple Endocrine Neoplasia Type 2B;   Multiple Endocrine Neoplasia Type 2A;   Atypical Hemolytic Uremic Syndrome;   Atypical HUS;   Wiedemann-Steiner Syndrome;   Breast Implant-Associated Anaplastic Large Cell Lymphoma;   Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA);   Hemophagocytic Lymphohistiocytosis;   Behcet's Disease;   Alagille Syndrome;   Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD);   Lowe Syndrome;   Pitt Hopkins Syndrome
    Intervention:  
    Sponsors:   Sanford Health;   National Ataxia Foundation;   International WAGR Syndrome Association;   4p- Support Group;   ML4 Foundation;   Cornelia de Lange Syndrome Foundation;   Stickler Involved People;   Kawasaki Disease Foundation;   Klippel-Feil Syndrome Alliance;   Klippel-Feil Syndrome Freedom;   Hyperacusis Research Limited;   Hypersomnia Foundation;   Kabuki Syndrome Network;   Kleine-Levin Syndrome Foundation;   Leiomyosarcoma Direct Research Foundation;   Marinesco-Sjogren Syndrome Support Group;   Mucolipidosis Type IV (ML4) Foundation;   People with Narcolepsy 4 People with Narcolepsy (PWN4PWN);   Soft Bones Incorporated;   American Multiple Endocrine Neoplasia Support;   Atypical Hemolytic Uremic Syndrome Foundation;   All Things Kabuki;   Wiedemann-Steiner Syndrome Foundation;   Breast Implant Victim Advocates;   PROS Foundation;   American Behcet's Disease Association
    Recruiting
  • Comparison of ALD, NASH, and Healthy Control Patients

    Condition:   ALD - Alcoholic Liver Disease
    Intervention:   Other: Blood draw
    Sponsor:   The Cleveland Clinic
    Recruiting
  • IL-1 Signal Inhibition in Alcoholic Hepatitis

    Condition:   Alcoholic Hepatitis
    Interventions:   Drug: Canakinumab 150mg/ml solution for injection;   Drug: Placebo
    Sponsors:   Imperial College London;   Novartis Pharmaceuticals
    Recruiting
  • Self-Affirmation: Construct Validity

    Condition:   Risk Reduction Behavior
    Intervention:  
    Sponsor:   National Cancer Institute (NCI)
    Recruiting
  • Comparison of Inflammatory Profiles and Regenerative Potential in Alcoholic Liver Disease

    Conditions:   Liver Diseases;   Acute on Chronic Hepatic Failure
    Intervention:   Other: collection of liver biopsies collection of blood samples
    Sponsor:   University Hospital, Lille
    Recruiting
  • Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE)

    Conditions:   Post Traumatic Stress Disorder;   Problem Drinking
    Intervention:   Behavioral: Web-based intervention
    Sponsors:   University of Washington;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

    Conditions:   Schizophrenia;   Cannabis Dependence;   Prodromal for Psychotic Illness;   Family History of Alcoholism;   Healthy Control
    Intervention:   Radiation: [11-C]OMAR
    Sponsors:   Yale University;   National Institute on Drug Abuse (NIDA);   National Institute of Mental Health (NIMH)
    Recruiting
  • Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study

    Conditions:   Alzheimer Disease;   Alzheimer Dementia;   Vascular Dementia;   Lewy Body Disease;   Lewy Body Dementia With Behavioral Disturbance (Disorder);   Dementia, Mixed;   Parkinson-Dementia Syndrome;   Chronic Traumatic Encephalopathy;   Huntington's Dementia;   Wernicke Korsakoff Syndrome;   Traumatic Brain Injury;   Dementia, Multi-Infarct;   Autism;   Autism Spectrum Disorder;   Autistic Behavior;   Autistic Disorder, Current or Active State;   Cadasil
    Interventions:   Procedure: Intravenous Bone Marrow Stem Cell (BMSC) Fraction;   Procedure: Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction;   Procedure: Near Infrared Light
    Sponsor:   MD Stem Cells
    Recruiting
  • Study to Evaluate Hepatic Artery Injection of Autologous Human Bone Marrow-Derived MSCs in Patients With Alcoholic LC

    Condition:   Alcoholic Liver Cirrhosis
    Intervention:   Biological: Cellgram™ (Bone marrow-derived MSCs)
    Sponsor:   Pharmicell Co., Ltd.
    Not yet recruiting
  • Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis

    Conditions:   Alcoholic Hepatitis;   Sepsis
    Interventions:   Drug: Vitamin C;   Drug: Dextrose 5% in water
    Sponsors:   Virginia Commonwealth University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting
  • Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis- Assessment of Impact on Prognosis and Short-term Outcome

    Condition:   Severe Alcoholic Hepatitis
    Interventions:   Other: Fecal Microbiota Transplantation;   Other: Standard of care treatment
    Sponsor:   Postgraduate Institute of Medical Education and Research
    Recruiting
  • Effect of Omega 5 Fatty Acid as an Adyuvant Treatment to Prednisone in Patients With Severe Alcoholic Hepatitis

    Condition:   Alcoholic Hepatitis
    Interventions:   Dietary Supplement: Omega 5 fatty acid supplement;   Other: PLACEBO
    Sponsors:   Hospital General Dr. Manuel Gea González;   Universidad Nacional Autonoma de Mexico
    Recruiting
  • GCSF in Alcoholic Hepatitis

    Condition:   Alcoholic Hepatitis
    Intervention:   Drug: GCSF
    Sponsor:   Postgraduate Institute of Medical Education and Research
    Recruiting
  • SMS-based Lifestyle Intervention for Patients With Liver Cirrhosis With Previous Hepathic Encephalopathy

    Condition:   Liver Cirrhosis, Alcoholic
    Interventions:   Behavioral: Supervised exercise;   Other: Usual Care;   Behavioral: SMS-messages
    Sponsor:   Marius Henriksen
    Recruiting
  • Efficacy and Safety of Orally Administered DS102 in Patients With Acute Alcoholic Hepatitis

    Condition:   Severe Acute Decompensated Alcoholic Hepatitis
    Interventions:   Drug: DS102;   Other: Placebo
    Sponsor:   Afimmune
    Not yet recruiting
  • A Research Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of DUR-928 in Patients With Alcoholic Hepatitis

    Condition:   Alcoholic Hepatitis
    Intervention:   Drug: DUR-928
    Sponsors:   Durect;   CTI Clinical Trial & Consulting Services
    Recruiting
  • BRIDGE Device for Post-operative Pain Control

    Conditions:   Liver Failure;   Liver Diseases, Alcoholic;   Liver Diseases;   Pain, Postoperative;   Transplant; Failure, Liver;   Liver Cirrhosis, Biliary
    Intervention:   Device: BRIDGE device
    Sponsor:   Duke University
    Recruiting
  • Pegfilgrastim in Patients With Alcoholic Hepatitis

    Condition:   Alcoholic Hepatitis
    Interventions:   Drug: Standard of care + pegfiltrastim;   Drug: Standard of care
    Sponsors:   Timothy Morgan, MD;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Comparison of Bovine Colostrum Versus Placebo in Treatment of Severe Alcoholic Hepatitis: A Randomized Double Blind Controlled Trial

    Condition:   Alcoholic Hepatitis
    Interventions:   Drug: Bovine Colostrum;   Drug: Placebo
    Sponsor:   Dayanand Medical College and Hospital
    Recruiting
  • Efficacy and Safety of G-CSF in Patients With Severe Alcoholic Hepatitis With Null or Partial Response to Steroid

    Condition:   Alcoholic Hepatitis
    Interventions:   Drug: G-CSF (Filgrastim injection);   Drug: steroid;   Drug: placebo
    Sponsor:   Chuncheon Sacred Heart Hospital
    Recruiting
  • Novel Therapies in Moderately Severe Acute Alcoholic Hepatitis

    Condition:   Acute Alcoholic Hepatitis
    Interventions:   Dietary Supplement: Lactobacillus Rhamnosus GG;   Drug: Placebo for Probiotic
    Sponsors:   University of Texas Southwestern Medical Center;   National Institute on Alcohol Abuse and Alcoholism (NIAAA);   The Cleveland Clinic;   University of Massachusetts, Worcester;   University of Louisville
    Recruiting
  • A Study of Molecular and Genetic Factors for Liver Cancer in the Greater Baltimore Area

    Conditions:   Carcinoma, Hepatocellular;   Liver Cirrhosis, Alcoholic;   Hepatitis, Alcoholic;   Hepatitis, Chronic;   Hepatitis, Viral, Human
    Intervention:  
    Sponsor:   National Cancer Institute (NCI)
    Recruiting
  • Project IMPACT: In-the-Moment Protection From Automatic Capture by Trigger

    Condition:   Substance Use Disorder
    Interventions:   Behavioral: Resonance Breathing;   Behavioral: Non-Resonance Breathing
    Sponsors:   Rutgers, The State University of New Jersey;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Brain Inflammation and Function in Alcoholism

    Condition:   Alcoholism
    Interventions:   Device: MRI;   Drug: C-11PBR28;   Drug: F-18FDG
    Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting
  • Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality

    Conditions:   Coronary; Ischemic;   Arrhythmias, Cardiac;   Heart Failure;   Peripheral Vascular Diseases;   Dementia;   Stroke;   Pulmonary Disease, Chronic Obstructive;   Respiratory Insufficiency;   Alcoholism;   Cancer;   Diabetes;   Renal Insufficiency
    Interventions:   Procedure: OPTI-AGED;   Procedure: Usual Care
    Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
    Recruiting
  • Retinoic Acid Homeostasis in Neuropsychiatric Diseases

    Conditions:   Major Depression;   Alzheimer's Disease;   Alcoholism;   Schizophrenia
    Intervention:  
    Sponsor:   Charite University, Berlin, Germany
    Recruiting
  • I2S-Health Prevention

    Condition:   Secondary School Student in General High School Who Does Not Have a Disability That Does Not Allow a Good Understanding of the Study Requirements
    Interventions:   Behavioral: Impulsive intervention;   Behavioral: Reflective Intervention
    Sponsors:   Institut de Cancérologie de la Loire;   National Cancer Institute, France
    Recruiting
  • Digital Self-help Support for Lifestyle Behavior Changes Among Primary Care Outpatients With Mental Health Problems

    Conditions:   Mental Health;   Risk Reduction Behavior;   Primary Health Care
    Interventions:   Behavioral: Digital Health Profile;   Behavioral: Treatment as usual
    Sponsors:   Karolinska Institutet;   The Swedish Research Council
    Recruiting
  • First Years Away From Home: Letting Go and Staying Connected

    Conditions:   Substance Abuse;   Risk Reduction;   RIsky Sexual Behavior
    Interventions:   Behavioral: Handbook condition;   Behavioral: Handbook plus condition
    Sponsor:   Washington State University
    Recruiting
  • Veteran Peer Coaches Optimizing and Advancing Cardiac Health

    Conditions:   Cardiovascular Disease (CVD);   Hypertension;   Hyperlipemia;   Obesity
    Intervention:   Other: Community-based peer health coach intervention
    Sponsor:   VA Office of Research and Development
    Recruiting
  • Study of ISIS 703802 in Subjects With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease

    Conditions:   NAFLD;   Diabetes Mellitus, Type 2;   Hypertriglyceridemia;   Fatty Liver, Nonalcoholic
    Interventions:   Drug: ISIS 703802;   Drug: Placebo
    Sponsors:   Akcea Therapeutics;   Ionis Pharmaceuticals, Inc.
    Recruiting

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