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- Conditions: Health Knowledge, Attitudes, Practice; Overweight and Obesity
Intervention: Behavioral: Healthy Together
Sponsors: University of British Columbia; Public Health Agency of Canada (PHAC); The Bridge Youth and Family Services, Kelowna BC
Enrolling by invitation - Condition: Childhood Obesity
Intervention: Behavioral: Healthy Youth Living Program
Sponsors: Mayo Clinic; Rochester Alternative Learning Center
Active, not recruiting - Condition: Healthy
Intervention: Behavioral: Healthy eating blog
Sponsor: Laval University
Completed - Condition: Healthy
Intervention: Device: MRI data acquiring in healthy volunteers
Sponsor: Rennes University Hospital
Recruiting - Condition: Healthy Volunteers
Intervention: Other: Blood sample
Sponsor: The Netherlands Cancer Institute
Recruiting - Condition: Childhood Obesity
Intervention: Behavioral: Healthy Eating and Physical Activity
Sponsor: University of South Carolina
Completed - Condition: Sarcoma
Intervention: Procedure: Collection of healthy skin tissue
Sponsors: Centre Oscar Lambret; Institut de Biologie de Lille
Active, not recruiting - Condition: Healthy Volunteers
Intervention: Other: Whole blood
Sponsor: Progenity, Inc.
Recruiting - Condition: Healthy
Interventions: Drug: IW-1701; Drug: Matching Placebo
Sponsor: Cyclerion Therapeutics
Completed - Conditions: Weight, Body; Diet Habit
Intervention: Behavioral: Healthy Start to Feeding
Sponsors: University of Cincinnati; Children's Hospital Medical Center, Cincinnati
Recruiting - Condition: Healthy Adults
Interventions: Other: High Linoleic Acid Healthy Cookies; Other: High Oleic Acid Healthy Cookies
Sponsor: Ohio State University
Active, not recruiting - Conditions: Alcohol Abuse; Drug Use; Violence, Domestic; Child Abuse; Diet Modification; Health Behavior; Health Knowledge, Attitudes, Practice; Relationship, Family; Relation, Parent-Child; Emotional Stress
Intervention: Behavioral: Weaving Healthy Families Program
Sponsors: Tulane University; National Institutes of Health (NIH)
Recruiting - Conditions: Obesity; Health Behavior; Child Behavior; Child Obesity; Nutrition Disorders; Body Weight
Intervention: Behavioral: Family Healthy Living
Sponsors: University of Victoria; Childhood Obesity Foundation
Recruiting - Conditions: Type1diabetes; Cardiovascular Risk Factor
Intervention: Behavioral: Heart healthy intervention
Sponsor: Joslin Diabetes Center
Completed - Condition: Healthy
Intervention: Behavioral: Food-based dietary guidelines for healthier diet
Sponsors: Ethiopian Public Health Institute; Wageningen University; Food and Agriculture Organization (FAO); International Food Policy Research Institute
Not yet recruiting - Condition: Obesity
Intervention: Behavioral: Healthy Me, Healthy We
Sponsors: University of North Carolina, Chapel Hill; National Heart, Lung, and Blood Institute (NHLBI)
Completed - Conditions: Ulcerative Colitis; Crohn's Disease; Healthy
Intervention: Other: Threonine
Sponsors: Nestlé; The Hospital for Sick Children; Mount Sinai Hospital, Canada
Completed - Condition: Systemic Sclerosis
Interventions: Device: Measurment with Aspirational Medical Device; Device: Measurment with Cutometer MPA 580
Sponsors: Oliver Distler; Swiss Federal Institute of Technology
Enrolling by invitation - Condition: Healthy
Interventions: Other: Hyperpolarized Helium-3; Device: MRI
Sponsor: Western University, Canada
Recruiting - Condition: Weight Loss
Intervention: Behavioral: Diabetes Prevention Program Lifestyle Intervention (DPP-LI) with Healthy Bodies Healthy Souls (HBHS)
Sponsor: University of Arkansas
Enrolling by invitation - Condition: Healthy Volunteers
Interventions: Drug: PF-04965842; Drug: Moxifloxacin; Drug: Placebo
Sponsor: Pfizer
Completed - Conditions: Overweight; Obesity
Intervention: Behavioral: Healthy lifestyle promotion program
Sponsor: Centro de Investigación en Alimentación y Desarrollo A.C.
Recruiting - Condition: Healthy Volunteers
Intervention: Other: Hyperpolarized Xenon MRI
Sponsors: Western University, Canada; London Health Sciences Centre
Recruiting - Conditions: Exhaled Breath; Mass Spectrometry; Healthy Subjects
Intervention: Other: No intervention
Sponsors: University of Zurich; Swiss Federal Institute of Technology
Active, not recruiting - Conditions: Heart Failure; Heart Failure NYHA Class III; Heart Failure NYHA Class II; Heart Failure NYHA Class I; Heart Failure NYHA Class IV
Intervention: Other: healthy volunteers
Sponsor: John Parissis
Completed - Condition: Healthy
Intervention: Drug: OP-101
Sponsor: Orpheris, Inc.
Completed - Conditions: Cystic Fibrosis; Asthma
Interventions: Drug: Xenon-129; Device: Magnetic Resonance Imaging; Device: Lung Clearance Index
Sponsor: The Hospital for Sick Children
Recruiting - Conditions: Healthy; Osteo Arthritis Knee
Intervention: Drug: [Tc-99m]-RPI-T-087 Injection
Sponsor: Reiley Pharmaceuticals Inc.
Recruiting - Conditions: Cardiovascular Diseases; Endothelial Dysfunction; Metabolic Syndrome; Diet Modification
Interventions: Dietary Supplement: plant sterols; Other: healthy diet
Sponsor: National University, Singapore
Not yet recruiting - Condition: Obesity
Intervention: Behavioral: Healthy Beverages in Child Care
Sponsor: University of California, San Francisco
Completed - Condition: Hepatocellular Carcinoma
Intervention: Other: measuring hemodynamic parameters heart beat to heart beat during single-frequency exposure
Sponsor: Hospital Sirio-Libanes
Recruiting - Condition: Healthy
Interventions: Drug: BLI-489; Drug: placebo
Sponsor: Wyeth is now a wholly owned subsidiary of Pfizer
Completed - Condition: Healthy Volunteers
Intervention: Drug: [18F]MNI-958
Sponsor: Invicro
Completed - Condition: Mental Health Wellness 1
Interventions: Behavioral: Healthy Relationships Plus Program (HRPP); Behavioral: Control Condition (Classroom Activities)
Sponsors: Centre for Addiction and Mental Health; CAMH Foundation
Completed - Conditions: Brugada Syndrome; Sudden Death
Intervention: Drug: Ajmaline
Sponsor: St George's, University of London
Recruiting - Condition: Healthy Ankle
Interventions: Radiation: Cone Beam Computed Tomography; Radiation: Radiographs
Sponsors: Paragon 28; Focus Medical Design and Development
Active, not recruiting - Condition: Healthy
Intervention: Other: MUNIX
Sponsor: Assistance Publique Hopitaux De Marseille
Not yet recruiting - Condition: Healthy
Interventions: Drug: Matching placebo; Drug: BI 1181181 healthy elderly; Drug: BI 1181181 Healthy young
Sponsor: Boehringer Ingelheim
Terminated - Condition: Healthy
Intervention:
Sponsor: Odense University Hospital
Completed - Condition: Healthy Volunteer
Interventions: Drug: Fluorothyazinone 300 mg; Drug: Fluorothyazinone 600 mg; Drug: Fluorothyazinone 3900 mg
Sponsors: Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation; Center of Pharmaceutical Analytics
Completed - Condition: Feasibility
Interventions: Behavioral: The Papás Saludables, Niños Saludables Program; Behavioral: The Papás Saludables, Niños Saludables Wait-list Control
Sponsors: Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - Condition: Healthy
Intervention: Device: Single-Pulse Transcranial Magnetic Stimulation
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Completed - A Multiple Dose Study of TD-1211 in Healthy Volunteers and Patients With Opioid-Induced ConstipationConditions: Healthy; Opioid-induced Constipation
Interventions: Drug: TD-1211; Drug: Placebo
Sponsor: Theravance Biopharma
Completed - Condition: Healthy
Intervention: Drug: Olanzapine
Sponsor: Mclean Hospital
Recruiting - Condition: Healthy Volunteer
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - Conditions: Healthy Volunteers; Constipation
Interventions: Procedure: Cortical Evoked Potentials; Procedure: Transcranial motor evoked potentials; Procedure: Translumbosacral motor evoked potentials
Sponsor: Augusta University
Active, not recruiting - Condition: Healthy Volunteers
Intervention: Device: mobile spectrofluorimeter
Sponsor: Institut de Cancérologie de Lorraine
Completed - Conditions: Substance-Related Disorders; Mental Health
Intervention: Behavioral: SET-R/Healthy Home
Sponsors: University of Miami; National Institute on Minority Health and Health Disparities (NIMHD)
Completed - Condition: Healthy
Interventions: Drug: CVN424; Drug: Placebo
Sponsor: Cerevance Beta, Inc.
Active, not recruiting - Condition: Healthy
Interventions: Drug: Capsaicin; Device: Videofluoroscopic swallow study
Sponsors: University of Florida; National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - Condition: Healthy Subjects
Intervention: Diagnostic Test: High-Resolution anorectal manometry with the use of solid-state catheter
Sponsors: Russian Academy of Medical Sciences; State Scientific Centre of Coloproctology, Russian Federation; Federal Research Centre of Nutrition and Biotechnology
Not yet recruiting - Condition: Healthy Volunteers
Intervention: Drug: American ginseng
Sponsors: Johns Hopkins University; National Center for Complementary and Integrative Health (NCCIH)
Completed - Conditions: Healthy Volunteers; Sickle Cell Disease
Interventions: Drug: FT-4202/Placebo; Drug: FT-4202
Sponsors: Forma Therapeutics, Inc.; Medpace, Inc.
Recruiting - Condition: Health Behavior
Interventions: Behavioral: Healthy Parent Carers group programme; Behavioral: Healthy Parent Carers online resources
Sponsors: University of Exeter; University of Oxford
Recruiting - Condition: Attention Deficit Hyperactivity Disorder
Interventions: Other: experience 1 : Competitive attention test in healthy participants; Other: experience 2 : Competitive attention test in patients with ADHD with no treatment; Other: experience 3 :Competitive attention test in patients with ADHD with psychostimulant treatment
Sponsor: Hospices Civils de Lyon
Not yet recruiting - Condition: Healthy-volunteers
Interventions: Drug: Rozanolixizumab; Drug: Placebo
Sponsor: UCB Biopharma S.P.R.L.
Recruiting - Condition: Healthy
Interventions: Drug: LEO 32731 modified release tablet; Drug: LEO 32731 blend, hard capsule; Drug: LEO 32731 API, hard capsule; Drug: LEO 32731 soft capsule; Drug: LEO 32731 gastro-resistant capsule; Drug: LEO 32731; Other: Placebo
Sponsor: LEO Pharma
Recruiting - Condition: Healthy
Intervention:
Sponsor: The Hospital for Sick Children
Recruiting - Conditions: Blood Pressure; Body Weight
Intervention: Behavioral: Packed Promise for a Healthy Heart
Sponsors: Oklahoma State University Center for Health Sciences; The Chickasaw Nation; Washington State University
Recruiting - Condition: Healthy Subjects
Intervention: Biological: Benralizumab
Sponsor: AstraZeneca
Active, not recruiting - Conditions: Healthy Volunteers; Statins; Immune Modulation
Intervention:
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Completed - Condition: Healthy
Interventions: Drug: PF-04965842; Drug: Probenecid
Sponsor: Pfizer
Not yet recruiting - Condition: Gastroparesis
Intervention: Other: Observational
Sponsor: Stanford University
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: [18F]MNI-1054
Sponsor: Invicro
Completed - Conditions: Healthy; Dietary Supplement
Interventions: Drug: Ozone; Dietary Supplement: Fish Oil; Dietary Supplement: Olive Oil
Sponsors: University of North Carolina, Chapel Hill; Environmental Protection Agency (EPA)
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: belatacept
Sponsor: Bristol-Myers Squibb
Completed - Condition: Healthy
Interventions: Drug: GLPG3121 SAD; Drug: Placebo SAD; Drug: GLPG3121 MAD; Drug: Placebo MAD
Sponsor: Galapagos NV
Recruiting - Conditions: Sepsis; Septic Shock; Sepsis Syndrome; Severe Sepsis
Intervention: Diagnostic Test: Septic
Sponsors: University of Leicester; The Royal College of Anaesthetists; University Hospitals, Leicester
Recruiting - Condition: Healthy
Intervention: Drug: omaveloxolone
Sponsor: Reata Pharmaceuticals, Inc.
Recruiting - Condition: Obesity
Interventions: Behavioral: Healthy Lifestyle; Behavioral: Positive Parenting
Sponsors: University of Massachusetts, Worcester; Oak Hill Community Development Corporation; Worcester Public Schools
Completed - Conditions: Healthy Subject; Hematologic and Lymphocytic Disorder; Hematopoietic and Lymphoid Cell Neoplasm; Immune System Disorder; Malignant Neoplasm
Interventions: Procedure: Biospecimen Collection; Other: Laboratory Biomarker Analysis; Other: Questionnaire Administration
Sponsors: University of Southern California; National Cancer Institute (NCI)
Recruiting - Condition: Healthy
Intervention: Diagnostic Test: MRI and concomitant perfused manometry of bowel motility
Sponsors: University of Nottingham; Food and Drug Administration (FDA); University of Michigan
Completed - Condition: Healthy
Interventions: Drug: AL-794; Drug: Placebo
Sponsor: Alios Biopharma Inc.
Terminated - Condition: Healthy Volunteers
Intervention: Other: Inhaled Nitrogen
Sponsors: Massachusetts General Hospital; Rezoagli, Emanuele, M.D., Massachusetts General Hospital, Harvard Medical School; Ferrari, Michele, M.D., Massachusetts General Hospital, Harvard Medical School; Patel, Sarvagna, B.A., Massachusetts General Hospital, Harvard Medical School; Zapol, Warren M., M.D., Massachusetts General Hospital, Harvard Medical School; Fisher, Daniel, R.R.T., Massachusetts General Hospital, Harvard Medical School; Jain, Isha, B.A., Massachusetts General Hospital, Harvard Medical School; Mootha, Vamsi, M.D., Massachusetts General Hospital, Harvard Medical School; Harris, Stuart N., M.D., Massachusetts General Hospital, Harvard Medical School; Karaa, Amel, M.D., Massachusetts General Hospital, Harvard Medical School
Recruiting - Conditions: Intervention; Food Allergy; Food Preferences; Food Intolerance; Diet Habit; Diet Modification
Intervention: Behavioral: Multicomponent intervention
Sponsors: University Rovira i Virgili; Diputació de Tarragona
Recruiting - Condition: Hypoxemia
Intervention: Other: HFNC flow
Sponsors: Rush University Medical Center; Shanghai Zhongshan Hospital
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: Ionis AGT-LRx; Drug: Placebo
Sponsor: Ionis Pharmaceuticals, Inc.
Completed - Condition: Healthy
Intervention: Drug: salvianolic acid A
Sponsor: Peking University First Hospital
Recruiting - Conditions: Drug Interaction; Healthy Volunteer
Interventions: Drug: Entinostat; Drug: Midazolam
Sponsor: Syndax Pharmaceuticals
Completed - Conditions: Healthy Volunteer; Fatigue; Depression
Intervention:
Sponsor: National Institute of Nursing Research (NINR)
Completed - Condition: Healthy
Interventions: Drug: MSB11455; Drug: US-Neulasta
Sponsor: Merck KGaA, Darmstadt, Germany
Completed - Condition: Healthy
Intervention: Device: Optical coherence tomography angiography (Zeiss Cirrus HD OCT 5000 AngioPlex)
Sponsor: Semmelweis University
Active, not recruiting - Condition: Psoriasis
Interventions: Drug: Placebo; Drug: VTP-43742
Sponsor: Vitae Pharmaceuticals Inc., an Allergan affiliate
Completed - Conditions: Obstructive Sleep Apnea; Healthy Subjects
Interventions: Drug: Placebo; Drug: Lemborexant 10 mg; Drug: Lemborexant 25 mg
Sponsors: Eisai Inc.; Purdue Pharma LP
Completed - Condition: Reference Values of BNP in Healthy Newborn
Intervention: Procedure: Blood sample and BNP measurement
Sponsor: Instituto de Cardiología y Medicina Vascular Hospital Zambrano-Hellion Tec Salud
Completed - Conditions: Weight Gain; Pregnancy Related
Interventions: Behavioral: Healthy for Two, Healthy for You; Behavioral: Health Education
Sponsors: Johns Hopkins University; Mid-Atlantic Nutrition Obesity Research Center
Completed - Condition: Healthy
Interventions: Drug: MSB11455; Drug: Neulasta
Sponsor: Merck KGaA, Darmstadt, Germany
Completed - Condition: Healthy Subjects
Intervention: Device: EndoFLIP™ System with FLIP Topography Module
Sponsor: Medtronic - MITG
Not yet recruiting - Condition: Healthy Volunteers
Interventions: Drug: Vemlidy (tenofivir alafenamide); Drug: Priftin (rifapentine); Drug: Isoniazid; Dietary Supplement: Pyridoxine
Sponsor: National Institutes of Health Clinical Center (CC)
Recruiting - Condition: Healthy Volunteer
Intervention:
Sponsor: National Institute of Mental Health (NIMH)
Recruiting - Conditions: Hyperactivity; Chronic Rhinosinusitis (Diagnosis); Chronic Rhinitis; Upper Respiratory Disease
Intervention: Other: Questionnaire
Sponsor: Universitaire Ziekenhuizen Leuven
Recruiting - Condition: Healthy
Interventions: Drug: HNC042 single dose; Drug: Placebo single dose; Drug: HNC042 multiple ascending doses; Drug: Placebo multiple ascending doses
Sponsor: Guangzhou Henovcom Bioscience Co. Ltd.
Recruiting - Condition: Healthy Subjects
Intervention: Drug: VNRX-5133 + cefepime
Sponsors: VenatoRx Pharmaceuticals, Inc.; National Institutes of Health (NIH)
Completed - Condition: Healthy Subjects
Interventions: Drug: E2027; Drug: E2027 matched placebo
Sponsor: Eisai Inc.
Completed - Condition: Hypokinesia
Interventions: Behavioral: Zero-time Exercise; Behavioral: Healthy Eating
Sponsors: The University of Hong Kong; Caritas Medical Centre, Hong Kong; The Hong Kong Jockey Club Charities Trust
Completed - Condition: Healthy
Intervention: Other: Probiotic yogurt drink
Sponsors: McMaster University; Mitacs
Active, not recruiting - Condition: Cardiovascular Risk Factor
Intervention: Behavioral: South Asian Healthy Lifestyle Initiative (SAHELI)
Sponsors: Northwestern University; Metropolitan Asian Family Services; Skokie Health Department; NorthShore University HealthSystem; Case Western Reserve University; Shirley Ryan AbilityLab
Recruiting - Condition: Healthy Subjects
Intervention: Drug: Epanova
Sponsor: AstraZeneca
Completed - Condition: Healthy
Interventions: Other: 16% O2 gas in breathed air; Other: 26% O2 gas in breathed air
Sponsor: Mclean Hospital
Not yet recruiting - Condition: Healthy Participants
Interventions: Drug: SP16; Drug: Placebos
Sponsors: Serpin Pharma, LLC; George Mason University; Virginia Commonwealth University
Active, not recruiting - Condition: Healthy
Intervention: Drug: Linezolid oral tablet 300 mg/day for 5 day
Sponsor: Prince of Songkla University
Active, not recruiting - Condition: Healthy
Interventions: Drug: BLI-489; Drug: Placebo
Sponsor: Wyeth is now a wholly owned subsidiary of Pfizer
Completed - Conditions: Diabetes; Wound Infection; Healthy Volunteers
Interventions: Drug: Tedizolid; Procedure: Microdialysis Catheter Insertion
Sponsors: Hartford Hospital; Merck Sharp & Dohme Corp.
Completed - Conditions: Musculoskeletal Disease; Obesity; Psychological Disorder
Intervention: Behavioral: Healthy Life Center
Sponsors: Norwegian University of Science and Technology; Western Norway University of Applied Sciences
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: MN-166
Sponsor: MediciNova
Completed - Condition: Healthy Subjects
Intervention: Drug: BGB-3111 and Drug Cocktail
Sponsor: BeiGene
Completed - A 6-Week Study to Evaluate Photoallergic Skin Reaction of CCP-020 (Diacerein 1%) in Healthy SubjectsCondition: Healthy
Intervention: Drug: CCP-020 Diacerein 1% topical ointment and vehicle ointment
Sponsor: Castle Creek Pharmaceuticals, LLC
Completed - Condition: Healthy
Interventions: Drug: placebo; Drug: raxibacumab
Sponsors: Human Genome Sciences Inc.; GlaxoSmithKline; Emergent BioSolutions
Completed - Condition: Sedentary Lifestyle
Interventions: Behavioral: i-STAND; Other: Healthy Living control
Sponsors: Kaiser Permanente; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - Condition: Healthy
Intervention: Device: DELPhI (software as a medical device)
Sponsor: QuantalX Neuroscience
Not yet recruiting - Condition: Healthy Volunteers
Intervention:
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - Condition: Healthy Volunteer
Interventions: Behavioral: Neurophysiological assessment; Behavioral: Neuropsychological assessment
Sponsor: University Hospital, Tours
Recruiting - Conditions: Dietary Habits; Health Behavior; Eating Behavior
Interventions: Behavioral: Behavioral Gardening Exposure; Behavioral: Healthy Eating and Gardening Curriculum; Behavioral: Family Workshops
Sponsor: Fred Hutchinson Cancer Research Center
Not yet recruiting - Condition: Healthy
Intervention:
Sponsor: Weill Medical College of Cornell University
Active, not recruiting - Conditions: Healthy Subjects; Diabetic Retinopathy; Retinal Vein Occlusion
Interventions: Other: Dynamic Vessel Analyzer; Other: Oxymap T1
Sponsor: Medical University of Vienna
Completed - Condition: Healthy
Interventions: Drug: Metformin; Drug: PF-04965842
Sponsor: Pfizer
Completed - Condition: Alzheimer's Disease
Interventions: Drug: florbetapir F 18; Drug: 18F-AV-1451
Sponsor: Avid Radiopharmaceuticals
Completed - Conditions: Sedentary Lifestyle; Overweight; Eating Disorders
Interventions: Other: Healthy lifestyle; Other: physical activity and dietary guidelines
Sponsor: The University of Hong Kong
Recruiting - Condition: Healthy
Interventions: Drug: Afamelanotide Group 1; Drug: Afamelanotide Group 2
Sponsor: Clinuvel Pharmaceuticals Limited
Completed - Condition: Healthy Male Volunteers
Interventions: Biological: HLX12; Biological: Cyramza (Ramucirumab)
Sponsor: Shanghai Henlius Biotech
Not yet recruiting - Condition: Healthy
Intervention: Diagnostic Test: High resolution esophageal manometry
Sponsor: Russian Academy of Medical Sciences
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: Microgestin®; Drug: Levothyroxine; Drug: Glyburide; Drug: Digoxin; Drug: IW-3718
Sponsor: Ironwood Pharmaceuticals, Inc.
Recruiting - Condition: Healthy
Intervention: Other: Healthy Volunteers
Sponsor: Centre Hospitalier Universitaire de Nice
Completed - Condition: Healthy Volunteer
Intervention: Drug: CC-92480
Sponsor: Celgene
Recruiting - Condition: Healthy Volunteers
Intervention:
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - Condition: Healthy
Intervention: Other: Diet based on inulin-rich vegetables
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Completed - Condition: Healthy Volunteers
Intervention: Diagnostic Test: Hyperpolarized Helium 3 Magnetic Resonance Imaging
Sponsors: Western University, Canada; London Health Sciences Centre
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: ALPN-101; Drug: Placebo
Sponsors: Alpine Immune Sciences, Inc.; Clinical Network Services (CNS) Pty Ltd
Recruiting - Condition: Obesity
Intervention: Behavioral: Evaluate Healthy Lifestyle Program on cognitive outcomes
Sponsor: Dartmouth-Hitchcock Medical Center
Not yet recruiting - Conditions: Diet Modification; Cognitive Decline; Cognitive Change
Interventions: Other: Multicultural Healthy Diet; Other: Usual Diet plus Self-Care
Sponsors: Albert Einstein College of Medicine; Penn State University; University of Pennsylvania; University of Minnesota - Clinical and Translational Science Institute; National Institute on Aging (NIA)
Recruiting - Condition: Healthy
Interventions: Drug: GMI-1359; Drug: Placebo
Sponsors: GlycoMimetics Incorporated; Celerion
Completed - Condition: Healthy Volunteers
Intervention: Device: Magnetic Resonance Imaging
Sponsor: Rennes University Hospital
Recruiting - Condition: Healthy
Interventions: Drug: LY3437943; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Condition: Healthy Volunteers
Interventions: Biological: INO-A002; Device: CELLECTRA® 2000; Device: Dengue Fever Antibodies (IgG)
Sponsors: University of Pennsylvania; Inovio Pharmaceuticals
Recruiting - Condition: Healthy Participants
Interventions: Drug: E2730; Drug: Placebo
Sponsor: Eisai Inc.
Completed - Condition: Healthy
Intervention: Dietary Supplement: sucralose 48 mg (splenda)/day for ten weeks
Sponsor: Hospital General de México Dr. Eduardo Liceaga
Completed - Condition: Healthy
Interventions: Drug: EHP-101 Liquid single dose; Drug: EHP-101 Liquid multiple doses; Drug: Matching placebo
Sponsor: Emerald Health Pharmaceuticals Inc.
Recruiting - Condition: Toxoplasmosis
Interventions: Drug: Pyrimethamine; Drug: Calcium folinate
Sponsor: GlaxoSmithKline
Completed - Condition: Healthy Volunteers
Interventions: Drug: AB680; Other: Placebo
Sponsor: Arcus Biosciences, Inc.
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: Lenvatinib
Sponsor: Eisai Inc.
Completed - Condition: Healthy, Male
Interventions: Drug: SYO-1644; Drug: Nexavar tab
Sponsors: Samyang Biopharmaceuticals Corporation; Seoul National University Hospital
Not yet recruiting - Conditions: Pregnancy Prevention; Life Skill Development
Intervention: Behavioral: Healthy Adolescent Transitions (HAT) program
Sponsors: Jack Stevens; OhioHealth Research and Innovation Institute
Recruiting - Condition: Healthy
Interventions: Drug: LY3002815; Drug: Placebo
Sponsor: Eli Lilly and Company
Terminated - Condition: Idiopathic Pulmonary Arterial Hypertension
Interventions: Drug: (Pyr1)apelin-13; Drug: Saline
Sponsor: Imperial College London
Completed - Condition: Healthy
Interventions: Drug: Daratumumab; Drug: Placebo; Drug: rHuPH20
Sponsor: Janssen Research & Development, LLC
Active, not recruiting - Condition: Healthy Participants
Interventions: Drug: TS-143; Drug: Placebo
Sponsor: Taisho Pharmaceutical Co., Ltd.
Completed - Conditions: Crohn's Disease; Ulcerative Colitis; Healthy Controls
Intervention:
Sponsors: The Hospital for Sick Children; Mount Sinai Hospital, New York; Crohn's and Colitis Foundation
Recruiting - Condition: Allergic Disorder
Intervention: Biological: ASLAN004
Sponsors: Aslan Pharmaceuticals; IQVIA
Active, not recruiting - Condition: Healthy Volunteer
Interventions: Drug: CC-99677; Other: Placebo
Sponsor: Celgene
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: Lanadelumab
Sponsor: Shire
Completed - Conditions: Breast Cancer; Healthy Volunteer; Prostate Cancer
Intervention:
Sponsor: National Cancer Institute (NCI)
Completed - Conditions: Health Behavior; Ageing
Intervention: Behavioral: Peer-led Health Education
Sponsors: University of Alberta; Covenant Health
Recruiting - Condition: Healthy Participants
Interventions: Drug: E6742; Drug: Placebo
Sponsor: Eisai Inc.
Completed - Condition: Inner Ear Disease
Interventions: Drug: SENS-401; Drug: Placebo
Sponsors: Simbec Research; Sensorion
Completed - Condition: Healthy Subjects
Interventions: Drug: ASP5354; Drug: Placebo
Sponsor: Astellas Pharma Global Development, Inc.
Recruiting - Condition: End Stage Renal Disease
Intervention: Drug: Triferic
Sponsor: Rockwell Medical Technologies, Inc.
Completed - Conditions: Healthy Volunteers; Influenza
Intervention:
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Completed - Condition: Obesity
Interventions: Behavioral: Healthy Eating & Active Living Taught at Home; Behavioral: Usual Care
Sponsor: Washington University School of Medicine
Recruiting - Condition: Healthy Adult Immune Response
Interventions: Biological: VRC-HIVMAB95-00-AB (10E8VLS); Biological: VRC-MAB075-00-AB (VRC07-523LS)
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Suspended - Condition: Healthy
Intervention: Drug: BDM-2 in Bottle (50 mg - 3600 mg); oral suspension
Sponsors: Hivih; Venn Life Sciences
Completed - Condition: Healthy Volunteers
Interventions: Biological: MGTA-145; Biological: plerixafor; Biological: Placebo
Sponsor: Magenta Therapeutics, Inc.
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: Tybost (Cobicistat); Drug: Prezcobix (Darunavir/Cobicistat); Drug: Xarelto (Rivaroxaban); Drug: Eliquis (Apixaban)
Sponsor: National Institutes of Health Clinical Center (CC)
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: Stiripentol
Sponsor: Biocodex
Recruiting - Condition: Healthy Subject
Interventions: Behavioral: Behavioral Dietary Intervention; Behavioral: Behavioral Intervention
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Active, not recruiting - Condition: Healthy
Interventions: Biological: MVA Mosaic; Biological: Placebo
Sponsors: Crucell Holland BV; US Military HIV Research Program; National Institute of Allergy and Infectious Diseases (NIAID); Beth Israel Deaconess Medical Center
Completed - Condition: Iron-refractory, Iron-deficiency Anemia (IRIDA)
Interventions: Drug: Triferic; Drug: Fer-In-Sol; Drug: Shohl's solution
Sponsor: Rockwell Medical Technologies, Inc.
Completed - Condition: Prostatic Neoplasms
Intervention: Drug: Zolpidem
Sponsor: National Cancer Institute (NCI)
Recruiting - Condition: Healthy Subjects
Intervention: Drug: Betrixaban
Sponsor: Portola Pharmaceuticals
Completed - Condition: Healthy
Intervention:
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Terminated - Condition: Healthy Subjects
Intervention: Diagnostic Test: High resolution anorectal manometry, water perfused catheter
Sponsors: Russian Academy of Medical Sciences; State Scientific Centre of Coloproctology, Russian Federation; Federal Research Centre of Nutrition and Biotechnology
Not yet recruiting - Conditions: Heart Disease; Cardiovascular Disease; Sedentary Lifestyle; Overweight; Obesity
Interventions: Behavioral: Strong Hearts, Healthy Communities; Behavioral: Strong Hearts, Healthy Women
Sponsors: Cornell University; Montana State University; Tufts University; Bassett Healthcare
Active, not recruiting - Conditions: Teen Dating Violence; Healthy Dating Relationship Behaviors
Interventions: Behavioral: Dating Matters Comprehensive Approach; Behavioral: Standard of Care Safe Dates Approach
Sponsors: Centers for Disease Control and Prevention; NORC at the University of Chicago; Ogilvy Public Relations; Alameda County Public Health Department; Baltimore City Health Department; Broward County Health Department; Chicago Department of Public Health
Completed - Condition: Healthy Volunteers
Interventions: Drug: TS-134; Drug: Placebo
Sponsor: Taisho Pharmaceutical R&D Inc.
Completed - Conditions: Idiopathic CD4 Positive; T-Lymphocytopenia
Intervention:
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - Conditions: Health Behavior; Aging
Interventions: Behavioral: Problem-solving; Behavioral: Education
Sponsor: Washington State University
Recruiting - Condition: Healthy
Interventions: Drug: Placebo; Drug: BI 1358894; Drug: BI 1358894 (Test); Drug: BI 1358894 (Reference)
Sponsor: Boehringer Ingelheim
Completed - Condition: Normal Healthy Volunteers Without Chronic Medical Conditions
Intervention: Procedure: cardiac PET stress test
Sponsor: Ochsner Health System
Not yet recruiting - Condition: Healthy Volunteers
Interventions: Drug: TS-134; Drug: Placebo
Sponsor: Taisho Pharmaceutical R&D Inc.
Completed - Condition: Healthy Volunteer
Interventions: Drug: MRG-110; Drug: Placebo
Sponsor: miRagen Therapeutics, Inc.
Completed - Condition: Human
Intervention: Behavioral: Health in the right measure
Sponsor: Universidade Federal do Rio de Janeiro
Active, not recruiting - Condition: Healthy Volunteers, Gluten
Interventions: Other: Gluten; Other: Placebo
Sponsor: Universitaire Ziekenhuizen Leuven
Completed - Condition: Healthy Volunteer
Interventions: Drug: BIIB095; Drug: Placebo
Sponsor: Biogen
Completed - Condition: Healthy
Intervention: Drug: tofacitinib modified-release (MR) formulation
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Dietary Supplement: NutriterraTM; Dietary Supplement: Placebo
Sponsors: Nuseed Americas Inc.; Nutrasource Diagnostics Inc.
Recruiting - Condition: Healthy Subjects
Interventions: Drug: ACT-709478; Drug: Placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy
Interventions: Drug: M5717; Drug: Placebo
Sponsor: Merck KGaA, Darmstadt, Germany
Recruiting - Condition: Healthy
Intervention: Drug: ZMAPP
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Withdrawn - Condition: Healthy
Interventions: Drug: JNJ-64565111; Drug: Placebo
Sponsor: Janssen Pharmaceutical K.K.
Recruiting - Condition: Healthy
Interventions: Drug: LXI-15028 50mg; Drug: LXI-15028 100mg; Drug: LXI-15028 200mg; Drug: Placebo
Sponsor: Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.
Completed - Condition: Immunotherapy
Interventions: Biological: Part A) Healthy subjects; Biological: Part B) Advanced solid tumor
Sponsor: Ajou University School of Medicine
Recruiting - Condition: Healthy Participants
Interventions: Drug: E6130; Drug: Placebo
Sponsor: EA Pharma Co., Ltd.
Withdrawn - Condition: Healthy Subjects
Interventions: Drug: PF-06751979 single dose; Drug: Placebo single dose; Drug: PF-06751979 multiple ascending dose; Drug: Placebo multiple ascending dose; Drug: PF-06751979 multiple dose; Drug: Placebo multiple elderly dose
Sponsor: Pfizer
Completed - Condition: Freeze Dried Plasma in Healthy Volunteers
Interventions: Biological: Autologous Freeze Dried Plasma (FDP); Biological: Fresh Frozen Plasma (FFP)
Sponsor: U.S. Army Medical Research and Materiel Command
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: Apremilast
Sponsor: Celgene
Completed - Condition: Healthy
Interventions: Drug: JNJ-64264681; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Down Syndrome
Intervention: Device: High definition transcranial direct current stimulation
Sponsor: University of Wisconsin, Madison
Recruiting - Condition: Healthy
Interventions: Drug: Tepotinib test (Treatment Period 1); Drug: Tepotinib reference (Treatment Period 2); Drug: Tepotinib reference (Treatment Period 1); Drug: Tepotinib test (Treatment Period 2)
Sponsor: Merck KGaA, Darmstadt, Germany
Completed - Condition: Healthy Volunteer
Interventions: Drug: LBS-008; Drug: Placebos
Sponsors: RBP4 Pty Ltd; Belite Bio, Inc
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: SPR720 for SAD; Drug: Placebo for SAD; Drug: SPR720 for MAD; Drug: Placebo for MAD
Sponsors: Spero Therapeutics; Simbec Research
Recruiting - Condition: Anhedonia in Healthy Volunteers
Interventions: Dietary Supplement: Ulva Lactuca; Dietary Supplement: Placebo
Sponsors: CEN Biotech; CEN Nutriment; Biovet Conseil; Amadeite SAS
Completed - Condition: Healthy Male Volunteers
Intervention: Drug: [14]-AST2818
Sponsor: Allist Pharmaceuticals, Inc.
Enrolling by invitation - Condition: Healthy Volunteer
Interventions: Biological: MEDI4920 3 mg; Biological: MEDI4920 10 mg; Biological: MEDI4920 30 mg; Biological: MEDI4920 100 mg; Biological: MEDI4920 300 mg; Biological: MEDI4920 1000 mg; Biological: MEDI4920 3000 mg; Other: Placebo
Sponsor: MedImmune LLC
Completed - Condition: Healthy
Intervention: Drug: Human ADME
Sponsor: Trius Therapeutics LLC
Completed - Condition: Healthy Volunteers
Intervention: Drug: Bimekizumab
Sponsor: UCB Biopharma S.P.R.L.
Active, not recruiting - Condition: Healthy Participants
Interventions: Drug: BOS161721; Drug: Placebo
Sponsor: Boston Pharmaceuticals
Completed - Condition: Healthy Volunteers
Interventions: Drug: AZD4205; Drug: Placebo
Sponsor: Dizal (Jiangsu) Pharmaceutical Co., Ltd.
Recruiting - Condition: Healthy Subject
Intervention: Drug: Banapenem
Sponsor: Sihuan Pharmaceutical Holdings Group Ltd.
Completed - Conditions: Healthy Young; Electric Stimulation Therapy
Interventions: Device: Pulsed current; Device: Russian Current
Sponsor: Federal University of Rio Grande do Sul
Recruiting - Condition: Healthy
Interventions: Drug: Inhaled Placebo; Drug: Inhaled Loxapine
Sponsor: Alexza Pharmaceuticals, Inc.
Completed - Condition: Healthy
Interventions: Drug: IPI-145; Drug: Midazolam
Sponsor: Verastem, Inc.
Completed - Condition: Healthy Volunteers
Interventions: Combination Product: PRT064445/Apixaban; Combination Product: Placebo/Apixaban; Drug: Placebo
Sponsor: Portola Pharmaceuticals
Completed - Condition: Healthy
Interventions: Other: Test Product; Other: Control Product 1; Other: Control Product 2
Sponsors: Danone Asia Pacific Holdings Pte, Ltd.; Nutricia Research
Active, not recruiting - Conditions: Sexual Behavior; Skills, Social; Skills, Coping
Interventions: Behavioral: Cadet Healthy Personal Skills; Behavioral: Standard Health Education
Sponsors: National Health Promotion Associates, Inc.; United States Air Force
Completed - Condition: Healthy Participants
Interventions: Drug: TS-143; Drug: Placebo
Sponsor: Taisho Pharmaceutical Co., Ltd.
Completed - Condition: Healthy
Interventions: Drug: CS-8080; Drug: placebo tablets
Sponsor: Daiichi Sankyo, Inc.
Terminated - Conditions: Fecal Incontinence in Old Age; Urinary Incontinence in Old Age
Intervention: Behavioral: Mind Over Matter; Healthy Bowels, Healthy Bladder
Sponsors: University of Wisconsin, Madison; Wisconsin Partnership Program
Completed - Conditions: Healthy Adult Subjects; Healthy Elderly Subjects
Interventions: Drug: PF-05251749; Drug: Melatonin
Sponsor: Pfizer
Completed - Condition: Depressive Disorder
Interventions: Drug: Paroxetine 12.5 milligrams tablet; Drug: Paroxetine 25 milligrams tablet; Drug: Paroxetine 50 milligrams tablet
Sponsor: GlaxoSmithKline
Completed - Conditions: Healthy; Type2 Diabetes
Intervention: Other: Dietary Intervention
Sponsors: University of Aberdeen; NHS Grampian
Recruiting - Condition: Healthy
Interventions: Drug: Olinciguat; Drug: Itraconazole
Sponsor: Cyclerion Therapeutics
Recruiting - Condition: IGF-1 Deficiency
Intervention:
Sponsor: Ipsen
Terminated - Condition: Healthy
Intervention: Drug: PF-04995274
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: IW-1973; Drug: Itraconazole
Sponsor: Cyclerion Therapeutics
Completed - Condition: Healthy
Interventions: Drug: Capsaicin; Drug: Placebo moisturizing cream
Sponsor: Wake Forest University
Completed - Conditions: Healthy Men; Male Contraception
Interventions: Drug: Placebo; Drug: 11β-methyl-nortestosterone-dodecylcarbonate
Sponsors: Health Decisions; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Los Angeles Biomedical Research Institute; University of Washington
Active, not recruiting - Condition: Healthy
Interventions: Drug: Fluticasone propionate; Device: Accuhaler
Sponsors: University Hospitals, Leicester; Genentech, Inc.
Active, not recruiting - Condition: Healthy Volunteers
Interventions: Drug: GSK3008356; Drug: Placebo
Sponsors: GlaxoSmithKline; Nucleus Network Ltd
Completed - Conditions: Stress; Psychological; Behavioral Symptoms; Sleep; Health Behavior; Weight, Body
Interventions: Behavioral: Meditation; Behavioral: Healthy Eating; Behavioral: Meditation + healthy eating
Sponsors: University of California, San Francisco; UCSF Healthy Campus Network; Headspace, Inc
Recruiting - Condition: Japanese Healthy Adult Male Participants
Interventions: Drug: E6130; Drug: Placebo
Sponsor: EA Pharma Co., Ltd.
Completed - Condition: Myelofibrosis
Intervention: Drug: Pacritinib
Sponsors: CTI BioPharma; SGS S.A.
Completed - Conditions: Obesity, Morbid; Insulin Resistance
Interventions: Biological: Fecal filtrate from 150 g stool from healthy lean donors; Biological: Fecal filtrate from 150 g of the recipient's own stool
Sponsors: Johane Allard; Canadian Institutes of Health Research (CIHR); MOUNT SINAI HOSPITAL; University of Toronto
Recruiting - Condition: Healthy
Interventions: Drug: Liquid pergoveris; Drug: Freeze-dried pergoveris
Sponsor: Merck KGaA, Darmstadt, Germany
Completed - Condition: Healthy Volunteers
Intervention: Drug: [14C]-praliciguat
Sponsor: Cyclerion Therapeutics
Recruiting - Conditions: Health Behavior; Quality of Life; Chronic Disease; Health Promotion; Stress; Mental Health Wellness 1
Interventions: Behavioral: Health and wellness learning sessions; Behavioral: Brainstorming group sessions; Behavioral: Individual sessions with a multidisciplinary health team; Behavioral: Health goal development; Behavioral: Physical activity and nutrition journals
Sponsor: McMaster University
Active, not recruiting - Condition: Healthy Volunteers
Intervention: Drug: [14C]-olinciguat
Sponsor: Cyclerion Therapeutics
Completed - Conditions: Overweight; Obesity
Intervention: Behavioral: Lifestyle Counseling
Sponsor: USDA Grand Forks Human Nutrition Research Center
Completed - Condition: Healthy Volunteers
Interventions: Drug: Treatment A - 400 mg Fasting; Drug: Treatment B - 400 mg Fed; Drug: Treatment C - 200 mg Fed
Sponsor: Daiichi Sankyo, Inc.
Active, not recruiting - Conditions: Lipidemia; Healthy
Interventions: Dietary Supplement: Viscous Fibre Blend; Dietary Supplement: Psyllium; Dietary Supplement: Wheat Bran
Sponsors: St. Michael's Hospital, Toronto; Kellogg Company; University of Toronto
Completed - Condition: Healthy Participants
Interventions: Drug: TAK-994; Drug: TAK-994 Placebo
Sponsor: Takeda
Recruiting - Condition: Healthy
Interventions: Drug: CCP-020 Diacerein 1% topical ointment; Drug: Vehicle
Sponsor: Castle Creek Pharmaceuticals, LLC
Completed - Condition: Healthy Volunteers
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Withdrawn - Condition: Alzheimer's Disease
Interventions: Drug: PU-AD; Drug: Placebo
Sponsor: Samus Therapeutics, Inc.
Not yet recruiting - Conditions: Type 2 Diabetes Mellitus; Dietary Habits
Intervention: Behavioral: App-technology for healthy eating habits
Sponsor: Karolinska Institutet
Recruiting - Condition: Altered Waking States of Consciousness in Healthy Humans
Intervention: Other: TMS/EEG
Sponsor: University of Zurich
Recruiting - Condition: Healthy
Intervention:
Sponsors: Wake Forest University Health Sciences; National Center for Complementary and Integrative Health (NCCIH); Office of Dietary Supplements (ODS)
Recruiting - Condition: Healthy Subjects
Interventions: Drug: ACT-541468 (hydrochloride salt); Drug: ACT-541468 (free base); Drug: Placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Conditions: Healthy; Parkinson Disease
Interventions: Drug: Lu AF82422; Drug: Placebo
Sponsor: H. Lundbeck A/S
Recruiting - Condition: Healthy
Interventions: Drug: PF-03382792 0.5mg; Drug: PF-03382792 1.5 mg; Drug: PF-03382792 5 mg; Drug: PF-03382792 15 mg
Sponsor: Pfizer
Withdrawn - Condition: Healthy
Intervention: Dietary Supplement: methionine
Sponsors: Texas A&M University; International Council on Amino Acid Science
Completed - Condition: Healthy
Interventions: Drug: SD-101; Drug: placebo
Sponsor: Dynavax Technologies Corporation
Completed - Condition: Healthy
Interventions: Biological: TDV; Biological: Placebo
Sponsor: Takeda
Completed - Condition: Healthy
Interventions: Drug: mibefradil; Other: Placebo
Sponsors: Cavion, Inc.; Celerion; Dana-Farber Cancer Institute; LifeWatch Services, Inc.
Completed - Condition: Healthy
Intervention: Drug: AG-221
Sponsor: Celgene
Completed - Condition: Hip Injuries
Intervention: Other: Healthy group
Sponsor: Hvidovre University Hospital
Completed - Condition: Healthy Volunteers
Interventions: Drug: MA-0211; Drug: Placebo
Sponsor: Astellas Pharma Global Development, Inc.
Completed - Condition: Healthy Subjects
Interventions: Drug: ESN364; Drug: Placebo
Sponsor: Astellas Pharma Inc
Completed - Condition: Healthy Volunteer
Intervention: Drug: CC-90001
Sponsor: Celgene
Recruiting - Condition: Healthy
Interventions: Drug: Canagliflozin (JNJ-28431754); Drug: Placebo
Sponsor: Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Completed - Study of a Single Dose of PRS-060 Administered by Oral Inhalation or IV Infusion in Healthy SubjectsCondition: Healthy Subjects
Interventions: Drug: PRS-060; Drug: Placebo
Sponsor: Pieris Australia Pty Ltd
Completed - Conditions: Pre Diabetes; Type 2 Diabetes Mellitus
Interventions: Drug: Metformin + Healthy diet; Drug: Metformin + Personalized diet
Sponsors: Garvan Institute of Medical Research; Weizmann Institute of Science
Recruiting - Condition: Healthy Donors
Intervention:
Sponsor: National Cancer Institute (NCI)
Enrolling by invitation - Condition: Healthy
Intervention: Dietary Supplement: Salmon Protein Hydrolysate
Sponsors: Hofseth Biocare ASA; KGK Science Inc.
Completed - Condition: Healthy Volunteers
Intervention: Drug: Lenvatinib 10 mg
Sponsor: Eisai Inc.
Completed - Condition: CD - Crohn's Disease
Intervention: Other: Blood tests, intestinal biopsies, stool samples, environmental exposure questionnaire and FFQ questionnaire
Sponsors: Sheba Medical Center; Weizmann Institute of Science; Washington University School of Medicine; Sun Yat-sen University
Recruiting - Condition: Healthy Volunteers
Interventions: Device: Imaging devices; Device: New Non Invasive Devices
Sponsor: University Hospital, Grenoble
Recruiting - Condition: Healthy Adults
Intervention: Other: TECH: Tablet Enhancement of Cognition and Health
Sponsor: Assuta Hospital Systems
Recruiting - Condition: Healthy
Intervention: Behavioral: cooling
Sponsor: King Saud University
Enrolling by invitation - Condition: Healthy
Interventions: Biological: PF-06946860; Other: Placebo
Sponsor: Pfizer
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: Pomalidomide; Other: Caffeine; Other: Tobacco
Sponsor: Celgene
Completed - Condition: Safety Issues
Intervention: Drug: Ga68-Dolacga Injection
Sponsor: Institute of Nuclear Energy Research, Taiwan
Enrolling by invitation - Condition: Healthy
Interventions: Drug: CR8020; Drug: Placebo
Sponsor: Janssen Pharmaceutical K.K.
Withdrawn - Conditions: Cardiovascular Diseases; Aging
Interventions: Other: Wolfberry; Other: Healthy diet
Sponsors: National University, Singapore; National University Hospital, Singapore; Ministry of Education, Singapore
Recruiting - Conditions: Asthma; Healthy
Intervention: Other: Assessment of E-nose measurements
Sponsors: Istituto di Biomedicina e Immunologia Molecolare Alberto Monroy; Campus Bio-Medico University
Completed - Conditions: Healthy Marriage; Healthy Relationship
Interventions: Behavioral: Couples Connecting Mindfully; Behavioral: ELEVATE
Sponsors: Auburn University; Mathematica Policy Research, Inc.; Department of Health and Human Services
Active, not recruiting - Condition: Healthy
Interventions: Drug: BI 425809; Drug: Donepezil
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy
Interventions: Drug: JNJ-55375515 Dose Level 1; Drug: JNJ-55375515 Dose Level 2; Drug: JNJ-55375515 Dose Level 3; Drug: JNJ-55375515 Dose Level 4; Drug: JNJ-55375515 Dose Level 5; Drug: JNJ-55375515 Dose Level 6; Drug: Placebo; Drug: JNJ-55375515
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy Chinese Volunteers
Interventions: Drug: TG-2349 (400 mg) plus DAG181 (200 mg); Drug: DAG181 (200 mg) plus TG-2349 (400 mg)
Sponsors: Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.; R&G Pharma Studies Co.,Ltd.
Completed - Condition: Weight
Intervention:
Sponsors: University of Pittsburgh; Temple University; Johns Hopkins University; Penn State University; Geisinger Clinic
Active, not recruiting - Condition: Healthy
Interventions: Other: Positron Emission tomography; Drug: PET Scan with PF-03654746
Sponsors: Pfizer; Yale University
Completed - Condition: Cystic Fibrosis
Interventions: Drug: Placebo; Drug: QBW251
Sponsor: Novartis Pharmaceuticals
Terminated - Condition: Healthy
Intervention: Drug: Aprepitant 125 mg
Sponsor: Nuformix Technologies Limited
Active, not recruiting - Condition: Healthy Subjects
Interventions: Drug: FM101 for SAD; Drug: Placebo for SAD; Drug: FM101 for MAD; Drug: Placebo for MAD
Sponsor: Future Medicine
Recruiting - Condition: Healthy
Interventions: Drug: AAI101 i.v.; Drug: Saline 0.9% infusion; Drug: Piperacillin i.v.; Drug: Cefepime i.v.
Sponsor: Allecra
Completed - Condition: Healthy
Interventions: Drug: Tramadol HCl; Drug: Moxifloxacin 400 mg; Drug: Tramadol HCl Placebo; Drug: Moxifloxacin Placebo
Sponsors: Janssen Scientific Affairs, LLC; Bausch Health Americas, Inc.; Cipher Pharmaceuticals Inc.
Completed - Condition: Healthy
Interventions: Drug: JNJ-64417184; Drug: Placebo
Sponsor: Janssen BioPharma, Inc.
Recruiting - Condition: Healthy
Intervention:
Sponsors: University of Campinas, Brazil; Instituto de Cardiologia Biocardios; University of Brasilia
Completed - Condition: Healthy
Intervention: Drug: CTP-692
Sponsor: Concert Pharmaceuticals
Recruiting - Condition: Healthy
Interventions: Drug: Metformin powder; Drug: Probiotics powder; Other: Placebo powder
Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: OMT-28; Other: Matching Placebo
Sponsor: Omeicos Therapeutics GmbH
Completed - Condition: Healthy
Intervention: Drug: Tucatinib
Sponsor: Seattle Genetics, Inc.
Recruiting - Condition: Healthy
Interventions: Dietary Supplement: Cherry concentrate; Dietary Supplement: Placebo concentrate
Sponsor: University of Exeter
Completed - Condition: Healthy
Intervention: Drug: Lu AF28996
Sponsor: H. Lundbeck A/S
Recruiting - Condition: Healthy
Interventions: Drug: MBA-P01; Drug: BOTOX
Sponsor: Medy-Tox
Completed - Conditions: Healthy Volunteers; Osteoarthritis
Interventions: Drug: LEVI-04; Drug: Placebo
Sponsors: Levicept; Hammersmith Medicines Research
Recruiting - Conditions: Healthy Volunteers; Brain Lesion
Interventions: Drug: P03277; Drug: Placebo
Sponsor: Guerbet
Completed - Condition: Healthy Subjects
Interventions: Drug: AC-084; Drug: Placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Terminated - Condition: Healthy
Interventions: Drug: HTL0030310; Drug: Pasireotide; Drug: Placebo
Sponsor: Heptares Therapeutics Limited
Active, not recruiting - Condition: Healthy
Interventions: Drug: Placebo oral capsule; Drug: RTA 1701 capsules
Sponsor: Reata Pharmaceuticals, Inc.
Recruiting - Condition: Healthy
Interventions: Biological: JNJ-72537634; Biological: Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Healthy
Interventions: Drug: JNJ-0440; Drug: Placebo
Sponsors: Janssen Pharmaceutical K.K.; Janssen Research & Development, LLC
Recruiting - Condition: Healthy
Intervention: Dietary Supplement: Molkosan
Sponsors: University of Aberdeen; A. Vogel
Completed - Condition: Healthy
Interventions: Drug: Polmacoxib and Tramadol combination; Drug: Polmacoxib; Drug: Tramadol hydrochloride
Sponsor: CrystalGenomics, Inc.
Recruiting - Conditions: Adult; Fatigue
Intervention: Other: Aerobic Exercise Training
Sponsor: George Mason University
Completed - Condition: Healthy
Interventions: Drug: Lidocaine patch 5%; Drug: Lidocaine Hydrochloride; Drug: Lidoderm 5 % Topical Patch
Sponsors: Nicole K Brogden; Long Island University
Recruiting - Condition: Healthy
Interventions: Drug: PF-04965842; Drug: Dabigatran
Sponsor: Pfizer
Completed - Condition: Healthy
Intervention: Drug: BI 425809 mixed with [C-14] BI425809
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Drug: CTP-692; Drug: Placebo
Sponsor: Concert Pharmaceuticals
Active, not recruiting - Condition: Healthy
Interventions: Dietary Supplement: fortified oil; Dietary Supplement: Placebo
Sponsor: National Nutrition and Food Technology Institute
Completed - Condition: Healthy
Interventions: Drug: PF-04965842; Drug: Rosuvastatin
Sponsor: Pfizer
Completed - Condition: Healthy Adult Asian Participants
Interventions: Drug: TAK-831; Drug: Placebo
Sponsor: Takeda
Recruiting - Condition: Healthy
Intervention: Drug: topical formulation of tacrolimus
Sponsor: LEO Pharma
Completed - Condition: Healthy
Intervention: Device: Respiratory muscle endurance training
Sponsor: Swiss Federal Institute of Technology
Recruiting - Condition: Healthy
Interventions: Drug: HCP1805; Drug: HCP1801
Sponsor: Hanmi Pharmaceutical Company Limited
Recruiting - Condition: Healthy
Interventions: Drug: JNJ-63733657; Drug: Placebo
Sponsor: Janssen Pharmaceutical K.K.
Recruiting - Condition: Healthy
Interventions: Drug: BI 1358894; Drug: Placebo
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy
Interventions: Drug: JNJ-56136379; Drug: Itraconazole
Sponsor: Janssen Sciences Ireland UC
Not yet recruiting - Conditions: Molybdenum Cofactor Deficiency (MoCD); Rare Autosomal Recessive Disorder; Deficiency of Activity of Molybdenum-dependent Enzymes (Sulfite Oxidase [SOX], Xanthine Dehydrogenase, and Aldehyde Oxidase)
Interventions: Drug: ALXN1101; Drug: Placebo
Sponsor: Origin Biosciences
Completed - Condition: Healthy
Interventions: Drug: CG1801; Drug: CGL1802
Sponsor: CrystalGenomics, Inc.
Recruiting - Condition: Healthy
Interventions: Drug: Meditoxin; Drug: Botox
Sponsor: Medy-Tox
Completed - Condition: Accessory Muscle
Intervention: Other: Loaded inspiratory muscle test
Sponsor: National Taiwan University Hospital
Completed - Condition: Healthy
Intervention: Drug: Tegoprazan 50mg
Sponsor: CJ HealthCare Corporation
Recruiting - Condition: Healthy
Intervention: Drug: Prazosin Hydrochloride
Sponsors: Centre for Addiction and Mental Health; Ontario Lung Association; Pfizer
Completed - Condition: Healthy Controls
Intervention: Drug: [18F]-FTC-146
Sponsor: Stanford University
Recruiting - Condition: Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions: Drug: AZD9977; Drug: Itraconazole
Sponsor: AstraZeneca
Completed - Condition: Healthy
Interventions: Drug: CDX-6114; Drug: Placebo
Sponsor: Codexis Inc.
Recruiting - Condition: Healthy Volunteers
Interventions: Dietary Supplement: Beta-arbutin; Other: Placebo
Sponsors: SP Nutraceuticals Inc.; Canadian Glycomics Network (GlycoNet)
Not yet recruiting - Condition: Healthy
Interventions: Drug: HEC53856; Drug: placebo
Sponsor: Sunshine Lake Pharma Co., Ltd.
Recruiting - Condition: Healthy
Intervention: Drug: 14C-CORT125281
Sponsor: Corcept Therapeutics
Completed - Condition: Healthy
Interventions: Drug: CDX-6114; Drug: Placebo
Sponsor: Codexis Inc.
Completed - Conditions: Overweight and Obesity; Academic Acheivement
Interventions: Behavioral: Healthy Summer Learners; Behavioral: 21st Century Summer Learning Center
Sponsor: University of South Carolina
Recruiting - Condition: Healthy
Interventions: Drug: MT-6345; Drug: MT-6345 Placebo
Sponsor: Mitsubishi Tanabe Pharma Development America, Inc.
Recruiting - Condition: Healthy
Interventions: Drug: Lu AF35700; Drug: Lu AF35700 iv
Sponsor: H. Lundbeck A/S
Completed - Condition: Healthy
Intervention: Drug: 14C-JNJ-56136379
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: ILT101; Drug: Placebo
Sponsors: Assistance Publique - Hôpitaux de Paris; Iltoo Pharma
Not yet recruiting - Condition: Healthy
Interventions: Other: Bread reference; Other: Product 1: Milk; Other: Product 2: Full fat milk + oat; Other: Product 3: Skim milk + oat, high fibre; Other: Product 4: Skim milk + oat, low fibre
Sponsor: Aventure AB
Recruiting - Condition: Healthy
Interventions: Biological: ExPEC4V (4 : 4 : 4 : 4); Biological: ExPEC4V (4 : 4 : 4 : 8); Biological: ExPEC4V (8 : 8 : 8 : 8); Biological: ExPEC4V (8 : 8 : 8 : 16); Biological: ExPEC4V (16 : 16 : 16 : 16); Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Active, not recruiting - Condition: Alzheimer Disease
Intervention: Drug: TEP
Sponsor: Immungenetics AG
Active, not recruiting - Condition: Healthy
Interventions: Drug: PF-05221304 Formulation A; Drug: PF-05221304 Formulation B
Sponsor: Pfizer
Completed - A Study to Investigate the Drug-drug Interactions Between ACT-541468 and Ethanol in Healthy SubjectsCondition: Healthy
Interventions: Drug: ACT-541468; Other: ACT-541468 placebo; Other: Ethanol 10%; Other: Ethanol placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy
Intervention: Drug: Evenamide
Sponsor: Newron Pharmaceuticals SPA
Recruiting - Condition: Healthy
Interventions: Drug: BI 1291583; Drug: Placebo
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy
Intervention: Drug: ACT-541468
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy
Interventions: Drug: Indoximod HCL (F2) tablets; Drug: Indoximod base formulation; Other: Placebo
Sponsor: NewLink Genetics Corporation
Completed - Condition: Healthy
Interventions: Drug: Transderm Scop®; Drug: Intravenous scopolamine hydrobromide
Sponsors: University of Iowa; University of Minnesota - Clinical and Translational Science Institute
Completed - Condition: Healthy Volunteers
Interventions: Drug: IW-6463; Drug: Matching Placebo
Sponsor: Cyclerion Therapeutics
Recruiting - Condition: Healthy
Intervention: Other: Sulfur amino acid restricted diet
Sponsors: Milton S. Hershey Medical Center; Orentreich Foundation for the Advancement of Science, Inc.
Completed - Condition: Healthy
Interventions: Other: Oral Placebo; Other: Oral Protein; Other: Enteral Protein
Sponsor: University of Exeter
Completed - Condition: Healthy Subjects
Interventions: Drug: Lemborexant; Drug: Alcohol; Drug: Placebo
Sponsors: Eisai Inc.; Purdue Pharma LP
Completed - Condition: Healthy
Interventions: Drug: LY3154207 Capsule; Drug: LY3154207 Tablet; Drug: Placebo; Drug: Fluconazole Tablet
Sponsor: Eli Lilly and Company
Not yet recruiting - Condition: Healthy
Interventions: Drug: Placebo; Drug: Lu AF76432
Sponsor: H. Lundbeck A/S
Completed - Condition: Healthy
Interventions: Drug: Clopidogrel 75 mg; Drug: Tegoprazan 50 mg; Drug: Esomeprazole 20 mg
Sponsor: CJ HealthCare Corporation
Recruiting - Condition: Healthy
Interventions: Drug: Lucerastat (Treatment A); Other: Placebo; Drug: Moxifloxacin; Drug: Lucerastat (Treatment B); Drug: Lucerastat (Treatment C)
Sponsor: Idorsia Pharmaceuticals Ltd.
Active, not recruiting - Condition: Healthy
Interventions: Drug: PF-06650833 alone; Drug: PF-06651600 alone; Drug: PF-06650833 together with PF-06651600
Sponsor: Pfizer
Completed - Condition: Healthy
Intervention: Drug: penicillin G benzathine
Sponsor: Pfizer
Completed - Condition: Arrhythmia
Intervention: Drug: GAP-134
Sponsor: Wyeth is now a wholly owned subsidiary of Pfizer
Completed - Condition: Healthy
Interventions: Other: Red Furu; Other: Tofu
Sponsor: Zhejiang University
Completed - Condition: Healthy
Intervention: Drug: BI 1467335
Sponsor: Boehringer Ingelheim
Not yet recruiting - Condition: Healthy
Interventions: Drug: CORT118335, 25 mg; Drug: Prednisone Oral Tablet; Drug: Glucose; Drug: Placebo oral suspension; Drug: CORT118335, 75mg; Drug: CORT118335, 225mg; Drug: CORT118335, 675mg; Drug: CORT118335, 600mg; Drug: CORT118335, 630mg; Drug: CORT118335, 375mg; Drug: CORT118335, 100mg; Drug: CORT118335, 300mg; Drug: CORT118335, 900mg; Drug: CORT118335, 150mg; Drug: CORT118335, 1500mg; Drug: Placebo oral capsule; Drug: CORT118335, dose to be determined
Sponsor: Corcept Therapeutics
Completed - Condition: Healthy Volunteers
Interventions: Drug: AG-221; Radiation: 14C AG-221
Sponsor: Celgene
Completed - Condition: Healthy
Interventions: Drug: JNJ-61393215; Drug: Ritonavir
Sponsor: Janssen Research & Development, LLC
Completed - Conditions: Hepatic Impairment; Healthy Volunteers
Intervention: Drug: CC-220
Sponsor: Celgene
Not yet recruiting - Condition: Healthy
Interventions: Drug: K-877 CR Tablet A; Drug: K-877 CR Tablet B; Drug: K-877 CR Tablet E; Drug: K-877 IR Tablet
Sponsor: Kowa Research Institute, Inc.
Completed - Condition: Healthy Adults
Intervention: Device: tDCS
Sponsor: The University of Texas at Dallas
Recruiting - Condition: Healthy
Interventions: Drug: Reboxetine; Drug: Rivastigmine; Drug: Placebo oral tablet
Sponsor: University of Oxford
Not yet recruiting - Condition: Healthy
Interventions: Drug: JNJ-64417184 600 (Oral Tablet Formulation); Drug: JNJ-64417184 (Oral Suspension Formulation)
Sponsor: Janssen Research & Development, LLC
Not yet recruiting - Condition: Healthy
Interventions: Other: Exercises focused on flexor muscles; Other: Exercises focused on extensor muscles
Sponsor: Hacettepe University
Recruiting - Condition: Healthy
Interventions: Drug: COL-144 50mg; Drug: COL-144 100mg; Drug: COL-144 200mg; Drug: COL-144 400mg; Drug: Placebo
Sponsor: IlDong Pharmaceutical Co Ltd
Not yet recruiting - Condition: Healthy
Intervention: Drug: Decitabine
Sponsor: EpiDestiny, Inc.
Completed - Condition: Healthy
Interventions: Drug: PF-04965842; Other: rifampin
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: BI 1358894; Drug: Placebo
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy
Interventions: Drug: ACT541468; Drug: ACT541468 placebo; Drug: Citalopram
Sponsor: Idorsia Pharmaceuticals Ltd.
Recruiting - Condition: Healthy
Interventions: Drug: Ponesimod dose range (2 - 20 mg); Drug: Placebo Propranolol; Drug: Propranolol 80 mg
Sponsor: Janssen Pharmaceutica N.V., Belgium
Recruiting - Condition: Healthy
Interventions: Drug: PB2452 Infusion; Drug: Placebo - Sodium Chloride; Drug: Ticagrelor Oral Tablet - Pre-Treatment; Drug: Ticagrelor Oral Tablet - Pre-Treatment and Post-Treatment
Sponsor: PhaseBio Pharmaceuticals Inc.
Completed - Condition: Healthy
Interventions: Drug: BI 685509; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Drug: JNJ-53718678, 2000 mg; Drug: JNJ-53718678, 3000 mg; Drug: JNJ-53718678, 4500 mg or Dose to be decided; Drug: JNJ-53718678 500 mg; Drug: JNJ-53718678 Placebo; Drug: Moxifloxacin 400 mg; Drug: Moxifloxacin Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Healthy
Intervention: Drug: K0706
Sponsor: Sun Pharma Advanced Research Company Limited
Recruiting - Condition: Healthy
Intervention: Drug: Apalutamide
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy Volunteers
Interventions: Drug: ETX0282; Drug: Cefpodoxime proxetil; Drug: Placebo
Sponsor: Entasis Therapeutics
Recruiting - Condition: Healthy Volunteer
Interventions: Drug: REGN5069; Drug: Placebo
Sponsor: Regeneron Pharmaceuticals
Recruiting - Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) Study of M5049 in Healthy ParticipantsCondition: Healthy
Interventions: Drug: M5049; Drug: Placebo
Sponsor: Merck KGaA, Darmstadt, Germany
Recruiting - Condition: Healthy
Interventions: Drug: HEC113995PA•H2O tablet; Drug: Placebo tablet
Sponsor: Sunshine Lake Pharma Co., Ltd.
Not yet recruiting - Condition: Healthy Subjects
Interventions: Drug: Exforge® tab 5/160mg, Crestor® tab 10mg; Drug: CJ-30060 5/160/10mg
Sponsor: CJ HealthCare Corporation
Recruiting - Condition: Healthy
Interventions: Drug: Lasmiditan; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: Midazolam; Drug: ID-082
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy Adults
Interventions: Device: active anodal tDCS; Device: sham tDCS; Device: active cathodal tDCS
Sponsor: The University of Texas at Dallas
Active, not recruiting - Condition: Literacy
Intervention: Behavioral: Ready and Healthy for Kindergarten Family Literacy program
Sponsor: Rutgers, The State University of New Jersey
Not yet recruiting - Condition: Healthy
Interventions: Drug: CORT118335 Oral; Drug: 14C-CORT118335 intravenous; Drug: 14C-CORT118335 oral
Sponsor: Corcept Therapeutics
Recruiting - Condition: Healthy
Interventions: Drug: SPARC001 type I; Drug: SPARC001 type II; Drug: Reference001 type I; Drug: Reference001 type II
Sponsor: Sun Pharma Advanced Research Company Limited
Completed - Condition: Healthy
Intervention: Drug: Eculizumab
Sponsor: Samsung Bioepis Co., Ltd.
Completed - Condition: Healthy
Interventions: Drug: SPARC001 type I; Drug: SPARC001 type II; Drug: Reference001 type I; Drug: Reference001 type II
Sponsor: Sun Pharma Advanced Research Company Limited
Completed - Condition: Healthy
Interventions: Drug: PF-05221304; Drug: Placebo
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: (S)-ketamine Oral Thin Film; Drug: (S)-ketamine IV Infusion; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Healthy
Interventions: Drug: hzVSF-v13; Drug: Placebo
Sponsor: ImmuneMed, Inc.
Enrolling by invitation - Condition: Healthy
Interventions: Drug: RD01; Drug: Placebo
Sponsor: Shengzhen Sciprogen Bio-pharmaceutical Co. Ltd
Recruiting - Condition: Healthy
Intervention: Biological: BCD-147
Sponsor: Biocad
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: Oral idronoxil suspension; Drug: NOX66 (A); Drug: NOX66 (B)
Sponsor: Noxopharm Limited
Not yet recruiting - Condition: Healthy
Intervention: Drug: [14C]PF-05221304
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: Indoximod base formulation; Drug: Indoximod HCL (salt) formulation; Other: Placebo
Sponsor: NewLink Genetics Corporation
Completed - Condition: Healthy
Interventions: Drug: HEC30654AcOH capsule; Drug: Placebo capsule
Sponsor: Sunshine Lake Pharma Co., Ltd.
Enrolling by invitation - Condition: Healthy Volunteers
Intervention: Dietary Supplement: Thymol
Sponsor: Innovus Pharmaceuticals, Inc.
Recruiting - Condition: Healthy
Interventions: Biological: CSL730; Other: Placebo
Sponsor: CSL Behring
Recruiting - Conditions: Healthy; Renal Insufficiency
Intervention: Drug: KBP-5074
Sponsor: KBP Biosciences
Completed - Condition: Healthy
Interventions: Drug: GX-I7; Drug: Placebo
Sponsor: Genexine, Inc.
Completed - Condition: Healthy
Interventions: Drug: BI 764198; Drug: Placebo
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy Subjects
Intervention: Drug: levoketoconazole
Sponsor: Cortendo AB
Completed - Condition: Healthy Subjects
Intervention: Drug: Perampanel
Sponsor: Eisai Co., Ltd.
Completed - Condition: Gastrointestinal Motility
Intervention: Dietary Supplement: Healthy
Sponsor: University of Bari
Not yet recruiting - Condition: Healthy
Intervention: Drug: Brexpiprazole
Sponsor: Otsuka Beijing Research Institute
Active, not recruiting - Condition: Healthy
Interventions: Drug: LY3361237 - SC; Drug: LY3361237 - IV; Drug: Placebo - SC; Drug: Placebo - IV
Sponsor: Eli Lilly and Company
Recruiting - Condition: Healthy
Interventions: Drug: BI 1015550; Drug: itraconazole
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Intervention: Drug: K0706
Sponsor: Sun Pharma Advanced Research Company Limited
Completed - Condition: Healthy
Intervention: Drug: BI 730357 mixed with [C-14]BI 730357 BS
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Drug: Lasmiditan; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Intervention: Drug: 18F-JNJ-64326067
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy
Interventions: Drug: ACT-1004-1239; Other: Placebo; Drug: ACT-1004-1239 (Food-effect subpart); Other: Placebo (Food-effect subpart)
Sponsor: Idorsia Pharmaceuticals Ltd.
Recruiting - Condition: Healthy
Interventions: Drug: LY2963016; Drug: Insulin Glargine (Lantus)
Sponsor: Eli Lilly and Company
Recruiting - Condition: Healthy
Interventions: Drug: Seltorexant 40 mg; Drug: Seltorexant 20 mg
Sponsors: Janssen Research & Development, LLC; Minerva Neurosciences
Recruiting - Condition: None (i.e. Healthy Volunteers)
Interventions: Drug: Levomilnacipran; Drug: Duloxetine; Drug: Placebos
Sponsors: University of Ottawa; Allergan
Recruiting - Condition: Healthy Subjects
Interventions: Drug: TP-6076; Procedure: Bronchoalveolar lavage
Sponsors: Tetraphase Pharmaceuticals, Inc.; PRA Health Sciences
Recruiting - Conditions: Myelodysplastic Syndromes; Acute Myeloid Leukemia; Cardio-vascular Surgery
Intervention: Other: Bone marrow analyses
Sponsors: Institut de Cancérologie de la Loire; Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Healthy
Interventions: Drug: LY3374849 - SC; Drug: Insulin Degludec - SC; Drug: LY3374849 - IV; Drug: Insulin Degludec - IV
Sponsor: Eli Lilly and Company
Recruiting - Condition: Healthy
Interventions: Dietary Supplement: Wild Blueberry Powder; Dietary Supplement: Placebo
Sponsors: King's College London; University of Reading
Recruiting - Condition: Healthy
Interventions: Drug: LY3372689; Diagnostic Test: [18F]LSN3316612
Sponsor: Eli Lilly and Company
Recruiting - Condition: Healthy
Interventions: Drug: PF-06700841 cream; Drug: White petrolatum
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: JNJ-42165279; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy
Interventions: Drug: LY3090106; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: Within-Subject Active vs Placebo Topical Applications; Drug: Within-Subject Active vs. Placebo Topical Applications
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: Ravidasvir; Drug: Danoprevir; Drug: Ritonavir; Drug: Placebo
Sponsor: Ascletis Pharmaceuticals Co., Ltd.
Completed - Condition: Healthy
Interventions: Drug: Seltorexant; Other: Placebo Matched to Seltorexant; Other: Placebo Matched to Moxifloxacin; Drug: Moxifloxacin Dose 1
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy Volunteers
Interventions: Drug: NPT520-34 (125 mg); Drug: Placebos (125 mg)
Sponsors: Neuropore Therapies Inc.; Celerion
Recruiting - Condition: Healthy
Interventions: Drug: M6495; Drug: Placebo
Sponsor: Merck KGaA, Darmstadt, Germany
Completed - Condition: Healthy
Interventions: Drug: GC4711 30mg; Drug: GC4711 60mg; Drug: GC4711 90mg; Drug: GC4711 120mg; Drug: Placebo
Sponsor: Galera Therapeutics, Inc.
Not yet recruiting - Condition: Healthy
Intervention: Drug: HRIG
Sponsor: Bio Products Laboratory
Active, not recruiting - Condition: Healthy
Interventions: Drug: IW-1973; Drug: Matching Placebo Tablet
Sponsor: Cyclerion Therapeutics
Completed - Condition: Healthy Volunteers
Intervention: Drug: ACE-2494 or placebo
Sponsor: Acceleron Pharma, Inc.
Active, not recruiting - Conditions: Systemic Lupus Erythematosus; Healthy
Interventions: Drug: JNJ-55920839; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy
Interventions: Drug: JNJ-64232025 IV; Drug: JNJ-64232025 SC; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy Volunteers
Intervention: Drug: SHR1459
Sponsor: Jiangsu HengRui Medicine Co., Ltd.
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: SB26; Drug: Placebo
Sponsor: Samsung Bioepis Co., Ltd.
Active, not recruiting - Condition: Healthy
Interventions: Drug: BI 685509; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Biological: Ad26.ZIKV.001 5*10^10 vp; Biological: Ad26.ZIKV.001 1*10^11 vp; Biological: Placebo
Sponsor: Janssen Vaccines & Prevention B.V.
Active, not recruiting - Condition: Healthy Volunteers
Interventions: Drug: CPL500036 compound; Drug: Placebo
Sponsors: Celon Pharma SA; National Center for Research and Development, Poland
Recruiting - Condition: Healthy Volunteer
Interventions: Drug: S-888711; Dietary Supplement: Calcium Antacid
Sponsor: Shionogi
Completed - Condition: Healthy Volunteers
Intervention: Drug: Bimekizumab
Sponsor: UCB Biopharma S.P.R.L.
Not yet recruiting - Condition: Healthy
Interventions: Drug: BI 1467335; Drug: BI 1467335 (C-14) intravenous solution
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Drug: Guselkumab Dose 1; Drug: Guselkumab Dose 2; Drug: Guselkumab Dose 3; Drug: Placebo
Sponsor: Janssen Pharmaceutical K.K.
Completed - Condition: Healthy
Interventions: Drug: BI 1265162; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Drug: JNJ-64991524 Dose Level 1; Drug: JNJ-64991524 Dose Level 2; Drug: JNJ-64991524 Dose Level 3; Drug: JNJ-64991524 Dose Level 4; Drug: JNJ-64991524 Dose Level 5; Drug: JNJ-64991524 Dose Level 6; Drug: Placebo; Drug: JNJ-64991524 Dose Level 7; Drug: JNJ-64991524 Dose Level 8; Drug: JNJ-64991524 Dose Level 9
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy
Interventions: Biological: Takeda's Tetravalent Dengue Vaccine Candidate (TDV); Biological: TDV New Formulation; Drug: Placebo; Drug: New Formulation Placebo
Sponsor: Takeda
Completed - Condition: Healthy
Interventions: Drug: HTL0014242; Drug: Placebo oral capsule
Sponsors: Heptares Therapeutics Limited; Covance
Recruiting - Condition: Healthy Participants
Intervention: Drug: BMS-986165
Sponsor: Bristol-Myers Squibb
Recruiting - Condition: Healthy
Intervention: Drug: Perampanel 6 MG
Sponsors: Weill Medical College of Cornell University; Eisai Inc.
Recruiting - Condition: Healthy
Interventions: Drug: LY3375880 IV; Drug: LY3375880 SC; Drug: Placebo IV; Drug: Placebo SC
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Intervention: Drug: tucatinib
Sponsor: Cascadian Therapeutics Inc.
Completed - Condition: Healthy
Interventions: Drug: PF-06700841; Drug: Placebo; Drug: moxifloxacin
Sponsor: Pfizer
Completed - Condition: Healthy
Intervention: Drug: Letrozole ISM
Sponsor: Rovi Pharmaceuticals Laboratories
Recruiting - Condition: Healthy People
Interventions: Drug: QL1206; Drug: Xgeva®
Sponsor: Qilu Pharmaceutical Co., Ltd.
Active, not recruiting - Condition: Healthy
Interventions: Drug: PF-06650833; Drug: placebo
Sponsor: Pfizer
Completed - Condition: Healthy Volunteer
Interventions: Drug: PF 06835919; Drug: Midazolam
Sponsor: Pfizer
Recruiting - Condition: Healthy Subject
Interventions: Drug: Saline; Drug: ACT-246475; Drug: rifampicin
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy
Interventions: Drug: BI 1323495; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Drug: TAK-831; Drug: Placebo
Sponsor: Takeda
Completed - Condition: Healthy
Interventions: Drug: IW-1701; Drug: Placebo
Sponsor: Cyclerion Therapeutics
Completed - Condition: Healthy Volunteers
Interventions: Drug: TAK-788; Drug: Itraconazole; Drug: Rifampin
Sponsor: Millennium Pharmaceuticals, Inc.
Recruiting - Pharmacokinetic/Pharmacodynamic Characteristics and Safety/Tolerability of MT921 in Healthy SubjectsCondition: Healthy Volunteers
Interventions: Drug: MT921; Drug: Placebo
Sponsor: Medy-Tox
Completed - Condition: Healthy Participants
Intervention: Drug: Fenebrutinib
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy Females
Interventions: Drug: PF-04965842; Drug: Ethinyl estradiol (EE) and levonorgestrel (LN)
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: AK0529; Other: Placebo
Sponsor: Ark Biosciences Inc.
Completed - Condition: Healthy Subjects
Interventions: Drug: Clazosentan; Drug: Placebo; Drug: Moxifloxacin
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy Volunteers
Interventions: Drug: BLU-782; Drug: Placebo; Drug: BLU-782 taken with food
Sponsor: Blueprint Medicines Corporation
Recruiting - Condition: Healthy
Interventions: Drug: Pimodivir; Drug: Cyclosporine
Sponsor: Janssen-Cilag International NV
Completed - Condition: Healthy
Intervention: Drug: teverelix TFA
Sponsor: Antev Ltd.
Active, not recruiting - Condition: Healthy Subjects
Intervention: Drug: Mucinex® ER 600 mg
Sponsor: Reckitt Benckiser Inc.
Completed - Condition: Healthy Subjects
Intervention: Drug: pracinostat
Sponsors: Helsinn Healthcare SA; Quotient Sciences
Enrolling by invitation - Condition: Healthy Volunteers
Interventions: Drug: Balovaptan therapeutic dose Treatment A; Drug: Balovaptan supra-therapeutic dose Treatment B; Drug: Active control [moxifloxacin] on Day 2 Treatment C; Drug: Active control [moxifloxacin] on Day 15 Treatment D; Drug: Placebo for Balovaptan Treatment C; Drug: Placebo for Balovaptan Treatment D; Drug: Placebo for Moxifloxacin Treatment A; Drug: Placebo for moxifloxacin Treatment B; Drug: Moxifloxacin Treatment C; Drug: Placebo for moxifloxacin Treatment C; Drug: Placebo for moxifloxacin Treatment D; Drug: Moxifloxacin Treatment D
Sponsor: Hoffmann-La Roche
Active, not recruiting - Condition: Healthy Subject
Interventions: Drug: Cohort 1: HL217 Ophathalmic Solution QD; Drug: Cohort 2: HL217 Ophathalmic Solution BID; Drug: Cohort 3: HL217 Ophthalmic Solution QID; Drug: Placebo Ophthalmic solution
Sponsor: Hanlim Pharm. Co., Ltd.
Completed - Condition: Healthy Subject
Interventions: Drug: BPI-3016; Drug: Placebo
Sponsor: Betta Pharmaceuticals Co., Ltd.
Recruiting - Condition: Healthy Participants
Interventions: Drug: BMS-986165; Drug: MMF
Sponsor: Bristol-Myers Squibb
Completed - Condition: Healthy
Intervention: Drug: PF-06669571
Sponsor: Pfizer
Completed - Condition: Healthy Volunteers
Intervention: Drug: A4250
Sponsors: Albireo; Celerion
Completed - Condition: Healthy Volunteer
Intervention: Drug: Baloxavir Marboxil
Sponsors: Hoffmann-La Roche; Shionogi
Not yet recruiting - Condition: Healthy Male Participants
Interventions: Drug: E3112; Other: Placebo
Sponsor: EA Pharma Co., Ltd.
Recruiting - Condition: Healthy
Interventions: Dietary Supplement: fortified bread; Dietary Supplement: supplement; Dietary Supplement: placebo
Sponsor: National Nutrition and Food Technology Institute
Completed - Condition: Healthy Subjects
Interventions: Drug: BIIB059; Drug: Placebo
Sponsor: Biogen
Completed - Condition: Healthy
Interventions: Drug: BI 764122; Drug: Placebo
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy Subjects
Interventions: Drug: Clazosentan; Drug: Rifampicin; Other: Saline (0.9% sodium chloride)
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy
Interventions: Drug: meropenem-vaborbactam; Drug: Placebo; Drug: Moxifloxacin
Sponsors: Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.); Biomedical Advanced Research and Development Authority
Completed - Conditions: Graft vs Host Disease; Healthy Volunteer; Graft-Versus-Host Disease
Intervention:
Sponsor: National Cancer Institute (NCI)
Completed - Condition: Healthy Volunteers
Interventions: Drug: RO7017773; Drug: Itraconazole
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy Participants
Interventions: Drug: BMS-986278; Drug: Rifampin
Sponsor: Bristol-Myers Squibb
Completed - Condition: Healthy Volunteer
Intervention: Drug: [14C] ASN002
Sponsor: Asana BioSciences
Completed - Condition: Healthy Subjects
Interventions: Drug: ASP8302; Drug: Placebo
Sponsor: Astellas Pharma Inc
Completed - Condition: Healthy
Interventions: Drug: tucatinib; Drug: placebo; Drug: moxifloxacin
Sponsor: Seattle Genetics, Inc.
Completed - Condition: Healthy Subjects
Interventions: Drug: Norketotifen Oral Capsule (Cohort 1); Drug: Norketotifen Oral Capsule (Cohort 2); Drug: Norketotifen Oral Capsule (Cohort 3); Drug: Norketotifen Oral Capsule (Multiple Dose Cohort); Drug: Placebo Oral Capsule
Sponsor: Emergo Therapeutics, Inc.
Completed - Condition: Healthy
Interventions: Drug: CP-601,927; Drug: Placebo
Sponsor: Pfizer
Withdrawn - Condition: Healthy
Interventions: Drug: ACT-246475; Drug: Clopidogrel; Drug: Prasugrel; Drug: Placebo; Drug: Ticagrelor
Sponsor: Idorsia Pharmaceuticals Ltd.
Recruiting - Condition: Healthy
Interventions: Drug: JNJ-64041575; Drug: Probenecid
Sponsor: Janssen-Cilag International NV
Completed - Condition: Healthy Volunteers
Interventions: Drug: SPR206; Drug: Placebo
Sponsors: Spero Therapeutics; Clinical Network Services (CNS) Pty Ltd
Recruiting - Condition: Healthy Volunteers
Intervention: Dietary Supplement: SPM Active
Sponsors: Queen Mary University of London; Metagenics, Inc.
Active, not recruiting - Conditions: Crohn's Disease; Genetic Predisposition
Intervention: Other: biomarkers
Sponsor: University Hospital, Lille
Recruiting - Condition: Sinusitis
Intervention: Other: Probiotics
Sponsor: Probionase Therapies Inc.
Recruiting - Condition: Healthy Male Subjects
Interventions: Drug: Exforge® tab 10/160mg, Crestor® tab 20mg; Drug: CJ-30060 10/160/20mg
Sponsor: CJ HealthCare Corporation
Completed - Condition: Healthy Subject
Intervention: Drug: HMS5552
Sponsor: Hua Medicine Limited
Completed - Condition: Healthy
Interventions: Drug: Lumicitabine; Drug: Piperacillin/Tazobactam
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy
Interventions: Drug: BI 473494; Drug: Placebo
Sponsor: Boehringer Ingelheim
Terminated - Condition: Healthy
Interventions: Dietary Supplement: Spices 1; Dietary Supplement: Spices 2; Dietary Supplement: Spices 3; Dietary Supplement: Herbs 1; Dietary Supplement: Herbs 2; Dietary Supplement: Control drink
Sponsors: Lund University; Anti-Diabetic Food Centre
Completed - Condition: Healthy
Interventions: Drug: LY3192767; Drug: Basal Insulin Peglispro; Drug: Insulin Glargine; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Intervention: Drug: Tenofovir exalidex (TXL)
Sponsor: ContraVir Pharmaceuticals, Inc.
Completed - Condition: Healthy
Interventions: Drug: Lumicitabine; Drug: Lansoprazole; Drug: Ranitidine
Sponsor: Janssen Research & Development, LLC
Terminated - Condition: Healthy
Interventions: Drug: JNJ-64140284; Drug: Fluorine-18 Labeled [18F]-JNJ-64511070
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy
Interventions: Drug: BI 409306; Drug: Moxifloxacin; Drug: Placebo matching to BI 409306
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy
Interventions: Drug: BI 894416; Drug: Placebo; Drug: BI 894416 (treatment X and Z); Drug: BI 894416 (treatment Y)
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Drug: JNJ-55308942 High Dose; Drug: JNJ-55308942 Low Dose; Drug: Levonorgestrel/Ethinyl Estradiol Fixed Dose combination (FDC); Drug: Drug Cocktail:Midazolam (2mg)/Omeprazole (20mg)/Dextromethorphan (30mg)
Sponsor: Janssen-Cilag International NV
Completed - Condition: Healthy Volunteer
Intervention: Drug: PHP-201 0.5% ophthalmic solution (topical eye drop)
Sponsor: pH Pharma
Completed - Condition: Healthy
Interventions: Drug: Lasmiditan; Drug: Placebo; Drug: Diphenhydramine
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Interventions: Drug: BMS-986177; Drug: Aspirin; Drug: Clopidogrel; Drug: Placebo (for BMS-986177)
Sponsor: Bristol-Myers Squibb
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: TransCon Treprostinil
Sponsor: Ascendis Pharma A/S
Terminated - Conditions: Atopic Dermatitis; Eczema; Ichthyosis Vulgaris
Intervention:
Sponsor: National Human Genome Research Institute (NHGRI)
Recruiting - Condition: Prevention Harmful Effects
Interventions: Behavioral: Healthy Sleep intervention; Behavioral: Healthy Nutrition intervention
Sponsors: Tel Aviv University; Israel Science Foundation
Active, not recruiting - Condition: Healthy Participants
Interventions: Drug: PF-06651600 10 mg tablets; Drug: Itraconazole Solution 200 mg
Sponsor: Pfizer
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: Entrectinib Form A; Drug: Entrectinib Form C
Sponsor: Genentech, Inc.
Completed - Condition: Symptomatic Obstructive Hypertrophic Cardiomyopathy
Interventions: Drug: CK-3773274; Drug: Placebo
Sponsor: Cytokinetics
Recruiting - Condition: Healthy Participants and Patients With Narcolepsy
Interventions: Drug: TAK-925; Drug: Placebo
Sponsor: Takeda
Completed - Condition: Healthy
Interventions: Drug: LY3305677; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: DWP14012 Amg; Drug: DWP14012 Bmg; Drug: Clarithromycin; Drug: Amoxicillin; Drug: Lansoprazole
Sponsor: Daewoong Pharmaceutical Co. LTD.
Recruiting - Condition: Healthy
Interventions: Drug: Ibuprofen D; Drug: Nurofen® for Children
Sponsors: Pharmtechnology LLC; ClinPharmInvest, LLC
Completed - Condition: Healthy Subjects
Interventions: Drug: nangibotide; Drug: Placebo
Sponsors: Inotrem; Richmond Pharmacology Limited
Completed - Condition: Healthy Participants
Interventions: Drug: BMS-986278; Other: Placebo
Sponsor: Bristol-Myers Squibb
Active, not recruiting - Condition: Healthy
Intervention: Device: tDCS
Sponsor: Universidade Federal de Pernambuco
Completed - Condition: Healthy Volunteers
Intervention: Drug: PEGFILGRASTIM
Sponsors: Adello Biologics, LLC; Celerion
Completed - Condition: Drug Interactions
Interventions: Drug: BAY1902607; Drug: Itraconazole
Sponsor: Bayer
Active, not recruiting - Condition: Healthy Participants
Interventions: Drug: BMS-986256; Other: Placebo
Sponsor: Bristol-Myers Squibb
Recruiting - Condition: Healthy Volunteer Study
Intervention: Drug: AST-008
Sponsor: Exicure, Inc.
Completed - Condition: Healthy
Interventions: Drug: Olanzapine; Drug: Placebo
Sponsor: State University of New York at Buffalo
Completed - Condition: Healthy
Interventions: Other: High-CML diet; Other: Low-CML diet
Sponsor: Universidad de Guanajuato
Completed - Condition: Healthy
Interventions: Drug: BI 456906; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Intervention: Other: Dietary Intakes
Sponsor: The Hospital for Sick Children
Recruiting - Condition: Healthy Adolescents
Interventions: Behavioral: Adaptive Attention Training; Behavioral: Active Control; Behavioral: Low-dose Adaptive Attention Training
Sponsors: University of California, San Francisco; How I Decide Foundation
Recruiting - Condition: Healthy
Interventions: Device: EOXY device; Device: Gold standard oximeter; Procedure: SaO2 sampling
Sponsors: BioSerenity; NAMSA; Université Catholique de Louvain
Completed - Condition: Healthy
Interventions: Drug: Mirikizumab - IV; Drug: Mirikizumab - SC; Drug: Placebo - IV; Drug: Placebo - SC
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: GL2702 GLARS-NF1; Drug: Omix Ocas
Sponsor: GL Pharm Tech Corporation
Completed - Condition: Healthy Volunteers
Interventions: Drug: Evinacumab; Drug: Placebo
Sponsor: Regeneron Pharmaceuticals
Completed - Condition: Healthy
Interventions: Drug: human recombinant anti-tumor necrosis factor alpha monoclonal antibody injection; Drug: adalimumab
Sponsor: Innovent Biologics (Suzhou) Co. Ltd.
Completed - Condition: Healthy Subjects
Interventions: Drug: BOS172767 tablets; Drug: BOS172767 liquid capsules; Drug: BOS172767 micronized capsules; Drug: BOS172767 immediate release capsules; Drug: BOS172767 matching placebo capsules; Drug: BOS172767 matching placebo tablets; Drug: Rabeprazole
Sponsor: Boston Pharmaceuticals
Completed - Condition: Healthy
Interventions: Drug: PF-04447943; Drug: Placebo; Drug: Moxifloxacin
Sponsor: Pfizer
Completed - Condition: Healthy Volunteers
Interventions: Drug: CRN01941 Oral Solution; Drug: CRN01941 Oral Capsule; Drug: Placebo Oral Solution; Drug: Placebo Oral Capsule
Sponsor: Crinetics Pharmaceuticals Inc.
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: Entrectinib Test Formulation (F1); Drug: Entrectinib Reference Formulation (F06)
Sponsor: Genentech, Inc.
Recruiting - Condition: Healthy Volunteer
Interventions: Drug: SAGE-718; Drug: Placebo
Sponsor: Sage Therapeutics
Completed - Condition: Healthy
Interventions: Drug: BI 1358894; Drug: Placebo; Drug: Midazolam
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy
Interventions: Drug: JNJ-64565111; Drug: Moxifloxacin; Drug: JNJ-64565111-matching Placebo; Drug: Moxifloxacin-matching Placebo
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy Volunteers
Interventions: Drug: BIIB067; Drug: 99mTc-MAG3-BIIB067
Sponsor: Biogen
Recruiting - Condition: Healthy
Interventions: Drug: Cozaar 100mg Tablet; Drug: Losartan potassium 100mg
Sponsors: Pharmtechnology LLC; Reliance Life Sciences Private Limited
Completed - Condition: Healthy Volunteers
Intervention: Biological: Tetravalent Dengue Vaccine Candidate
Sponsor: Takeda
Active, not recruiting - Condition: Healthy Volunteers
Intervention: Drug: carbidopa-levodopa
Sponsor: Hong Kong WD Pharmaceutical Co., Limited
Not yet recruiting - Condition: Healthy Volunteers
Interventions: Biological: Drug: INM004 Dose 1; Biological: Drug: INM004 Dose 2; Biological: Drug: INM004- Repeated dose; Other: Placebo
Sponsors: Inmunova S.A.; Hospital Italiano de Buenos Aires
Completed - Condition: Healthy
Interventions: Biological: Pen of SB5; Biological: PFS of SB5
Sponsor: Samsung Bioepis Co., Ltd.
Completed - Condition: Healthy Volunteer
Interventions: Drug: SAGE-718; Drug: Placebo
Sponsor: Sage Therapeutics
Completed - Condition: Healthy
Intervention: Drug: Darunavir/Cobicistat
Sponsor: Janssen Pharmaceutical K.K.
Completed - Condition: Healthy Participants
Intervention: Drug: TAK-438
Sponsor: Takeda
Completed - Condition: Microbiota Analysis in Healthy Subjects
Intervention: Other: Healthy Adults
Sponsors: University of Florida; National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting - Condition: Healthy Volunteer
Interventions: Drug: BIIB091; Drug: Placebo
Sponsor: Biogen
Recruiting - Condition: Healthy
Intervention:
Sponsor: Response Biomedical Corp.
Terminated - Condition: Healthy
Interventions: Other: High fat challenge breakfast; Other: High fat challenge breakfast with mixed-spices
Sponsors: Lund University; Anti-Diabetic Food Centre
Completed - Condition: Healthy Subjects
Interventions: Drug: Mucinex® SE; Drug: Vicks Cough Syrup for Chesty Coughs
Sponsor: Reckitt Benckiser Inc.
Completed - Condition: Healthy
Interventions: Dietary Supplement: B-GOS; Dietary Supplement: Maltodextrin
Sponsors: Clasado Limited; General Hospital, States of Jersey
Completed - Condition: Healthy Adult Volunteers
Interventions: Combination Product: Drug: OP0201; Combination Product: Drug: Placebo
Sponsor: Novus Therapeutics, Inc
Completed - Condition: Healthy Volunteers
Interventions: Drug: SPD422; Drug: Omeprazole
Sponsor: Shire
Completed - Condition: Infant Development
Interventions: Other: Formula A; Other: Formula B
Sponsor: Worthy Health
Not yet recruiting - Condition: Health Behavior
Intervention: Other: Progressive web app
Sponsor: Universidad Peruana Cayetano Heredia
Completed - Condition: Healthy
Interventions: Drug: VVZ-149 injection; Other: Placebo
Sponsor: Vivozon, Inc.
Completed - Condition: Healthy Subjects
Interventions: Drug: ID-085; Drug: Placebo oral capsule
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy
Interventions: Drug: Rilpivirine; Drug: Rilpivirine Long-acting Parenteral Formulation
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy Volunteers
Interventions: Drug: DWP14012; Drug: Placebo
Sponsor: Daewoong Pharmaceutical Co. LTD.
Not yet recruiting - Condition: Healthy Volunteers
Interventions: Drug: TAK-653; Drug: Placebo; Drug: Ketamine
Sponsor: Millennium Pharmaceuticals, Inc.
Recruiting - Condition: Healthy Male Subjects
Interventions: Other: Ergometry H; Other: Ergometry L
Sponsors: ARCIM Institute Academic Research in Complementary and Integrative Medicine; Universität Tübingen
Recruiting - Condition: Healthy
Interventions: Drug: BI 705564; Drug: Placebo
Sponsor: Boehringer Ingelheim
Withdrawn - Condition: Heart Failure,Balance
Intervention:
Sponsor: Hacettepe University
Enrolling by invitation - Condition: Healthy Participants
Interventions: Drug: RO7062931; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Healthy
Interventions: Dietary Supplement: Anthocyanin; Dietary Supplement: Placebo
Sponsors: Shaoguan University; Sun Yat-sen University
Completed - Condition: Healthy Volunteers
Interventions: Drug: AZD9977; Other: Placebo
Sponsors: AstraZeneca; Parexel
Completed - Condition: Healthy Subjects
Interventions: Drug: ACT-132577; Drug: Rosuvastatin
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy Volunteers
Interventions: Drug: HD201; Drug: EU-Herceptin; Drug: US-Herceptin
Sponsor: Prestige Biopharma Pte Ltd
Recruiting - Condition: Healthy Participants
Interventions: Drug: RO7020531; Other: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Healthy Participants
Interventions: Drug: E2082; Drug: Placebo
Sponsor: Eisai Co., Ltd.
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: SHP681; Drug: Placebo
Sponsor: Shire
Recruiting - Condition: Healthy
Interventions: Drug: BI 730357; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy Female Subjects
Interventions: Other: Ergometry H; Other: Ergometry L
Sponsors: ARCIM Institute Academic Research in Complementary and Integrative Medicine; Universität Tübingen
Recruiting - Condition: Healthy Subjects
Interventions: Drug: PF-06882961 Immediate Release Tablet; Drug: PF-06882961 Controlled Release Tablet (long); Drug: PF-06882961 Controlled Release Tablet (short); Drug: PF-06882961 Immediate Release Solution
Sponsor: Pfizer
Completed - Condition: Healthy Volunteers
Intervention: Drug: SHP643
Sponsor: Shire
Not yet recruiting - Condition: Healthy Volunteers
Interventions: Drug: ITI-214; Drug: Placebo
Sponsors: Intra-Cellular Therapies, Inc.; Laureate Institute for Brain Research, Inc.
Recruiting - Condition: Healthy
Interventions: Biological: sIPV; Biological: cIPV
Sponsor: Janssen Vaccines & Prevention B.V.
Completed - Condition: Healthy Volunteers
Interventions: Drug: RO7049389; Drug: Pitavastatin
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy Adult Subjects
Interventions: Drug: TJ003234; Drug: Placebo
Sponsor: I-Mab Biopharma Co. Ltd.
Recruiting - Condition: Healthy
Intervention: Drug: [^14C]-Risdiplam
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy Volunteers
Intervention: Drug: ropeginterferon alfa-2b
Sponsors: PharmaEssentia Japan K.K.; PharmaEssentia
Recruiting - Condition: Healthy Subjects
Interventions: Biological: JHL1922; Biological: dornase alfa
Sponsor: JHL Biotech, Inc.
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: Apixaban sprinkle capsules; Drug: Apixaban tablets
Sponsor: Bristol-Myers Squibb
Completed - Condition: Healthy Volunteers
Intervention: Drug: Dexlansoprazole
Sponsor: Takeda
Completed - Condition: Healthy
Interventions: Drug: Abemaciclib; Drug: Placebo; Drug: Loperamide
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Interventions: Drug: HD204; Drug: Avastin
Sponsor: Prestige Biopharma Pte Ltd
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: GDC-0134 F09 Formulation; Drug: GDC-0134 F15 Formulation; Drug: GDC-0134 F16 Formulation
Sponsor: Genentech, Inc.
Active, not recruiting - Condition: Healthy Volunteers
Interventions: Drug: TAK-418; Drug: TAK-418 Matching Placebo
Sponsor: Takeda
Terminated - Condition: Healthy
Interventions: Drug: JNJ-61803534; Drug: Placebo; Drug: Midazolam
Sponsor: Janssen Research & Development, LLC
Terminated - Condition: Healthy Subjects
Interventions: Drug: ACT-132577; Other: Placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy
Intervention: Drug: PF-06427878
Sponsor: Pfizer
Completed - Condition: Healthy Subject
Interventions: Drug: Dolcanatide; Other: Laboratory Biomarker Analysis; Other: Placebo; Other: Questionnaire Administration
Sponsor: National Cancer Institute (NCI)
Active, not recruiting - Condition: Healthy Participants
Interventions: Drug: AJM347; Drug: Placebo
Sponsor: EA Pharma Co., Ltd.
Completed - Condition: Healthy
Interventions: Drug: BI 1015550; Drug: Placebo
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy Male Volunteers
Intervention: Drug: AST2818 Tablets
Sponsor: Allist Pharmaceuticals, Inc.
Not yet recruiting - Condition: Healthy Volunteer
Interventions: Drug: ORM-12741; Drug: Placebo
Sponsors: University of Cape Town; Orion Corporation, Orion Pharma; University of Oxford
Completed - Condition: Healthy Volunteers
Intervention:
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Completed - Condition: Healthy Volunteers
Interventions: Drug: Placebo; Drug: IONIS PKK-LRx
Sponsor: Ionis Pharmaceuticals, Inc.
Completed - Condition: Healthy Volunteers
Interventions: Drug: TAK-925; Drug: TAK-925 Placebo; Drug: Modafinil; Drug: Modafinil Placebo
Sponsor: Takeda
Completed - Condition: Healthy Volunteer
Interventions: Drug: GDC-0853; Drug: Placebo
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy Volunteer
Interventions: Drug: SAGE-718; Drug: Placebo
Sponsor: Sage Therapeutics
Completed - Condition: Healthy Subjects
Intervention: Drug: ACT-246475
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Conditions: Pediatric Obesity; Obesity
Interventions: Behavioral: Healthy Caregivers- Healthy Children Toolkit; Behavioral: Safety Curriculum
Sponsor: University of Miami
Completed - Condition: Healthy
Interventions: Biological: SB5; Biological: EU sourced Humira®; Biological: US sourced Humira®
Sponsor: Samsung Bioepis Co., Ltd.
Completed - Condition: Healthy Volunteers
Interventions: Drug: Balovaptan; Drug: Rifampicin
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy Subject
Interventions: Drug: Benapenem; Drug: Placebo
Sponsor: Sihuan Pharmaceutical Holdings Group Ltd.
Completed - Condition: Healthy Volunteers
Interventions: Drug: Oral Balovaptan; Drug: IV Balovaptan
Sponsor: Hoffmann-La Roche
Active, not recruiting - Condition: Healthy Volunteers
Interventions: Drug: Balovaptan; Drug: Itraconazole
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy Volunteers
Interventions: Drug: Vortioxetine; Drug: Paroxetine; Drug: Placebo
Sponsor: Takeda
Completed - Condition: Healthy Adult Volunteers
Interventions: Drug: Cohort 1 - TT301/MW189; Drug: Cohort 2- TT301MW189; Drug: Cohort 3 - TT301/MW189; Other: Cohort 1 Placebo; Other: Cohort 2 Placebo; Other: Cohort 3 Placebo
Sponsors: Linda Van Eldik; Duke Clinical Research Institute; Alzheimer's Association
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: TS-161; Drug: TS-161 Placebo
Sponsor: Taisho Pharmaceutical R&D Inc.
Not yet recruiting - Condition: Healthy
Intervention:
Sponsor: National Taiwan University Hospital
Completed - Condition: Complement Mediated Bacterial Killing in Healthy Adults
Intervention:
Sponsors: University of Oxford; Wellcome Trust
Recruiting - Condition: Healthy Adult Subjects
Interventions: Drug: Roxadustat Tablet; Drug: Roxadustat Mini-tablet
Sponsors: Astellas Pharma Global Development, Inc.; FibroGen
Not yet recruiting - A Study of Safety, Tolerability, and Pharmacokinetics of Single Doses of PHP-303 in Healthy SubjectsCondition: Healthy Volunteer
Interventions: Drug: PHP-303; Other: Placebo
Sponsor: pH Pharma
Completed - Condition: Healthy
Interventions: Drug: GLPG1690; Drug: Itraconazole; Drug: Voriconazole
Sponsor: Galapagos NV
Completed - Condition: Healthy Subjects
Interventions: Drug: Venlafaxine; Drug: Moxifloxacin; Drug: Drug - placebo
Sponsor: Pfizer
Completed - Condition: Healthy Volunteers
Interventions: Drug: TAK-935 Tablets; Drug: TAK-935 Oral Solution
Sponsor: Takeda
Completed - Condition: Healthy Japanese Volunteers
Interventions: Drug: UCB0107; Other: Placebo
Sponsor: UCB Biopharma S.P.R.L.
Completed - Condition: Healthy Subjects
Interventions: Drug: AC-076 for s.c. administration; Drug: Placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy Chinese Volunteers
Interventions: Drug: Furaprevir capsule (SAD); Drug: Furaprevir capsule (MAD); Drug: Placebo (SAD); Drug: Placebo (MAD)
Sponsors: Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.; R&G Pharma Studies Co.,Ltd.
Completed - Condition: Healthy Volunteers
Interventions: Drug: Risdiplam; Drug: Placebo
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy Male Participants
Intervention: Drug: [14C]-E6007
Sponsor: EA Pharma Co., Ltd.
Completed - Condition: Healthy Recreational Drug Users
Interventions: Drug: ACT-541468; Drug: Suvorexant; Drug: Zolpidem; Drug: Placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Recruiting - Condition: Healthy
Interventions: Drug: Esketamine; Drug: Rifampin
Sponsor: Janssen Research & Development, LLC
Completed - Condition: Healthy Volunteers
Interventions: Drug: Cortexolone 17α-propionate solution; Drug: Placebo
Sponsor: Cassiopea SpA
Completed - Conditions: Smoking Cessation; Family; Health Behavior
Interventions: Behavioral: Quit Smoking for a Healthy Family; Behavioral: Healthy Living
Sponsors: University of California, San Francisco; University of California, Davis; Chinese Community Health Resource Center; Immigrant Resettlement & Cultural Center; Vietnamese Voluntary Foundation, Inc.; Southeast Asian Community Center
Active, not recruiting - Conditions: Weight Loss; Diet Modification; Physical Activity
Intervention: Behavioral: Healthy Moms
Sponsors: University of Connecticut; University of Massachusetts, Worcester; Worcester Polytechnic Institute; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - Condition: Healthy Male Subjects
Interventions: Biological: JHL1149; Biological: Bevacizumab
Sponsor: JHL Biotech, Inc.
Recruiting - Condition: Healthy Subjects
Interventions: Drug: Selexipag; Drug: Clopidogrel
Sponsor: Actelion
Completed - Condition: Healthy Participants
Intervention: Drug: Perampanel
Sponsor: Eisai Inc.
Completed - Condition: Healthy Volunteers
Interventions: Drug: Alogliptin; Drug: Pioglitazone; Drug: SYR-322-4833 BL
Sponsor: Takeda
Completed - Condition: Healthy Subjects
Interventions: Drug: ACT-541468 (Formulation A); Drug: ACT-541468 (Formulation B); Drug: Placebo (Formulation A); Drug: Placebo (Formulation B); Drug: 14C-labeled ACT-541468; Drug: Placebo tracer
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy Male Volunteers
Interventions: Drug: Placebo; Drug: E3112
Sponsor: EA Pharma Co., Ltd.
Completed - Condition: Healthy Volunteer
Interventions: Biological: Ad4-Env145NFL; Biological: Ad4-Env150KN; Biological: VRC-HIVRGP096-00-VP (Trimer 4571) with alum
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - Condition: Healthy
Interventions: Drug: ACT-451840 10 mg; Drug: ACT-451840 50 mg; Drug: ACT-451840 200 mg; Drug: ACT-451840 500 mg; Drug: ACT-451840 1000 mg; Drug: ACT-451840 (Dose to be determined); Drug: Placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy Controls
Interventions: Drug: OLANZapine 2.5 MG; Drug: Placebo; Drug: Insulin Lispro 100 UNT/ML; Other: Saline
Sponsors: Centre for Addiction and Mental Health; University Health Network, Toronto
Not yet recruiting - Condition: Healthy
Interventions: Biological: SB2; Biological: EU Remicade; Biological: US Remicade
Sponsor: Samsung Bioepis Co., Ltd.
Completed - Condition: Healthy Volunteers
Interventions: Drug: Glasdegib Therapeutic Exposure; Drug: Glasdegib Supra-therapeutic Exposure; Drug: Positive Control (Moxifloxacin); Other: Placebo Control
Sponsor: Pfizer
Completed - Condition: Healthy Subjects
Interventions: Drug: Cohort 1: HL217 Ophathalmic Solution BID; Drug: Cohort 2: HL217 Ophathalmic Solution QID; Drug: Placebo
Sponsor: Hanlim Pharm. Co., Ltd.
Completed - Conditions: Obesity; Nutrition Poor; Physical Activity; Weight Loss
Interventions: Behavioral: Healthy Frio In-Person Family-focused Intervention; Behavioral: Healthy Frio Remote Technology Family-focused Intervention; Behavioral: Control
Sponsors: University of Texas at Austin; The University of Texas at San Antonio; The University of Texas Health Science Center at San Antonio; University of Maryland
Recruiting - Condition: Healthy Volunteers
Interventions: Procedure: Transcranial direct current stimulation (tDCS); Procedure: Peripheral electrical stimulation (PES); Procedure: Sham tDCS
Sponsor: Universidade Federal do Piauí
Recruiting - Condition: Healthy
Interventions: Drug: Evacetrapib; Drug: Omeprazole
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Participants
Interventions: Drug: IONIS FXI-LRx; Drug: Placebo
Sponsor: Ionis Pharmaceuticals, Inc.
Active, not recruiting - Condition: Healthy Volunteer
Interventions: Drug: MHAB5553A; Drug: Matching placebo
Sponsor: Genentech, Inc.
Completed - Conditions: Pulmonary Disease, Chronic Obstructive; Emphysema or COPD; Microbiota
Intervention: Diagnostic Test: obtain samples from sputum, feces and urine
Sponsor: Asan Medical Center
Recruiting - Conditions: Inflammatory Bowel Diseases; IBD
Interventions: Drug: TD-1473 - Dose A; Drug: TD-1473 - Dose B; Drug: TD-1473 - Dose C; Drug: Placebo
Sponsor: Theravance Biopharma
Completed - Condition: Healthy Volunteer
Interventions: Drug: BAY1101042; Drug: Placebo
Sponsor: Bayer
Active, not recruiting - Condition: Healthy
Interventions: Drug: vapendavir 132 mg capsule; Drug: vapendavir 264 mg tablet; Drug: vapendavir 24 mg/mL oral suspension
Sponsor: Aviragen Therapeutics
Completed - Condition: Healthy Volunteers
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Completed - Conditions: Asthma; Healthy Subjects or Volunteers
Intervention: Biological: Tralokinumab 300 mg
Sponsor: MedImmune LLC
Completed - Condition: Healthy Male Volunteers
Interventions: Drug: UCB0107; Other: Placebo
Sponsor: UCB Biopharma S.P.R.L.
Completed - Condition: Healthy Volunteers
Interventions: Dietary Supplement: 2-HOBA; Dietary Supplement: Placebo
Sponsors: Metabolic Technologies Inc.; Vanderbilt University; National Institute on Aging (NIA)
Recruiting - Condition: Healthy
Interventions: Drug: BI 705564; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Conditions: Healthy Volunteers; Renal Impairment
Intervention: Drug: MK-6183
Sponsor: Cubist Pharmaceuticals LLC
Completed - Condition: Healthy Participants
Intervention: Drug: Gantenerumab
Sponsor: Hoffmann-La Roche
Completed - Condition: Healthy
Interventions: Drug: Safinamide 50 mg; Drug: Safinamide 100mg
Sponsor: Zambon SpA
Not yet recruiting - Condition: Healthy Term Infants
Interventions: Dietary Supplement: Formula regimen 1; Dietary Supplement: Formula regimen 2
Sponsor: Nestlé
Recruiting - A Study to Examine the Safety, Tolerability and Biological Effects of REGN4461 in Healthy VolunteersCondition: Healthy Volunteers
Interventions: Drug: REGN4461; Drug: Placebo
Sponsor: Regeneron Pharmaceuticals
Recruiting - Condition: Healthy Participants
Interventions: Drug: Placebo tablet matching lemborexant; Drug: Placebo tablet matching zopiclone; Drug: Zopiclone 7.5 mg; Drug: Lemborexant 2.5 mg; Drug: Lemborexant 5 mg; Drug: Lemborexant 10 mg
Sponsors: Eisai Inc.; Purdue Pharma LP
Completed - Condition: Healthy Men and Women
Interventions: Dietary Supplement: Placebo; Dietary Supplement: Concord Grape extract 1; Dietary Supplement: Concord Grape extract 2
Sponsors: King's College London; Naturex-Dbs
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: MB02; Drug: US licenced Avastin®; Drug: EU approved Avastin®
Sponsor: mAbxience S.A
Active, not recruiting - Condition: Healthy Volunteer
Interventions: Drug: Folic Acid; Drug: GDC-0853; Drug: Methotrexate; Drug: Rabeprazole
Sponsor: Genentech, Inc.
Completed - Condition: Healthy Volunteer Study
Interventions: Drug: Tranexamic Acid 1 gram intravenously; Drug: Tranexamic acid 2 grams oral solution; Drug: Tranexamic acid 1 gram intramuscular
Sponsor: London School of Hygiene and Tropical Medicine
Not yet recruiting - Condition: Healthy Participants
Intervention: Drug: Tbo-filgrastim
Sponsor: Teva Pharmaceutical Industries, Ltd.
Terminated - Condition: Healthy Volunteers
Interventions: Drug: RO7017773 Phase I Capsule; Drug: RO7017773 Phase II Tablet Unflavored; Drug: RO7017773 Phase II Tablet Sweetened/Flavored
Sponsor: Hoffmann-La Roche
Active, not recruiting - Condition: Healthy Volunteers
Interventions: Drug: Fludrocortisone 100 μg; Drug: Fludrocortisone 200 μg; Drug: Fludrocortisone 400 μg; Drug: Placebo
Sponsor: Rennes University Hospital
Completed - Condition: Healthy Volunteers
Interventions: Drug: GDC-0334; Drug: Placebo
Sponsor: Genentech, Inc.
Recruiting - Condition: Healthy Subjects
Intervention: Drug: Mucinex™ extended-release (SE)
Sponsor: Reckitt Benckiser LLC
Completed - Condition: Healthy Volunteers
Interventions: Drug: GDC-0853; Drug: Rabeprazole
Sponsor: Genentech, Inc.
Completed - Condition: Healthy Male Participants
Interventions: Drug: AG-881; Drug: [13C315N3]AG-881
Sponsor: Agios Pharmaceuticals, Inc.
Recruiting - Condition: Healthy Volunteers
Interventions: Biological: RO7049665; Biological: Placebo
Sponsor: Hoffmann-La Roche
Active, not recruiting - Conditions: Parkinson Disease; Alzheimer Disease; Healthy Controls; Multiple Sclerosis
Intervention: Drug: [123I]CLINDE
Sponsor: Institute for Neurodegenerative Disorders
Terminated - Conditions: Functional Constipation; Healthy
Interventions: Dietary Supplement: Actazin (green kiwi powder) High Dose; Dietary Supplement: Actazin (green kiwi powder) Low Dose; Dietary Supplement: Control Formula (Actazin green kiwi powder + PreticX prebiotic); Dietary Supplement: Livaux (gold kiwi powder) High Dose; Dietary Supplement: Livaux (gold kiwi powder) Low Dose; Dietary Supplement: Placebo (microcrystalline cellulose)
Sponsors: AIDP, Inc.; KGK Science Inc.
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: TAK-020; Drug: TAK-020 Placebo
Sponsor: Takeda
Completed - Condition: Pharmacokinetics and Safety in Healthy Volunteers
Interventions: Drug: 50 mg PTI-125; Drug: 100 mg PTI-125; Drug: 200 mg PTI-125
Sponsors: Pain Therapeutics; National Institutes of Health (NIH)
Completed - Condition: Healthy Volunteers
Interventions: Drug: TAK-788; Drug: Placebo; Drug: Drug: TAK-788
Sponsor: Millennium Pharmaceuticals, Inc.
Completed - Condition: Healthy Volunteer
Interventions: Drug: GDC-0310; Drug: Placebo
Sponsor: Genentech, Inc.
Completed - Condition: Psoriasis
Interventions: Biological: GSK2831781; Biological: Placebo
Sponsors: GlaxoSmithKline; Parexel
Completed - Conditions: Healthy Volunteers and Subjects With Disease; CAD
Interventions: Device: MRI scan x 1- Healthy volunteer; Device: MRI scan x 2- Healthy volunteer; Device: MRI scan x 2- CAD patients; Device: MRI scan x 2- non-CAD patients
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: MEDI7219; Drug: Placebo; Drug: Formulation without Active Drug
Sponsor: MedImmune LLC
Recruiting - Condition: Lassa Fever
Interventions: Drug: INO-4500; Drug: Placebo; Device: CELLECTRA® 2000
Sponsors: Inovio Pharmaceuticals; Coalition for Epidemic Preparedness Innovations (CEPI)
Recruiting - Condition: Healthy
Interventions: Drug: Oxycodone controlled-release test formulation; Drug: Immediate-release reference drug
Sponsor: Pfizer
Completed - Condition: Healthy Volunteers
Intervention:
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Healthy
Interventions: Drug: BIBR 1048 MS low dose; Drug: BIBR 1048 MS medium dose; Drug: BIBR 1048 MS high dose
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy Adult Immune Responses to Vaccine
Interventions: Biological: VRC-EBOADC069-00-VP; Biological: VRC-EBOADC076-00-VP
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed - Condition: Cystic Fibrosis
Interventions: Drug: BI 443651; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy Volunteer
Interventions: Drug: RO6870868; Drug: placebo
Sponsor: Hoffmann-La Roche
Completed - Condition: Childhood Obesity
Interventions: Behavioral: Healthy Homes; Other: Usual Care
Sponsor: University of Colorado, Denver
Active, not recruiting - Condition: Healthy
Interventions: Drug: PF-06260414; Drug: Placebo
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: Dichloroacetate (DCA); Other: GSTZ1 haplotyping
Sponsors: University of Florida; Medosome Biotec LLC; Food and Drug Administration (FDA)
Completed - Condition: Fetal and Neonatal Alloimmune Thrombocytopenia
Intervention: Other: Platelet transfusion
Sponsors: Prophylix Pharma AS; Larix A/S; Fraunhofer Institute for Molecular Biology and Applied Ecology; German Red Cross; Bioscientia Central Laboratory
Completed - Condition: Healthy
Interventions: Drug: BI 730460; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy Volunteers
Interventions: Behavioral: Prismatic goggles; Behavioral: Virtual reality device
Sponsor: Hospices Civils de Lyon
Not yet recruiting - Condition: Bioequivalence of Vitamin C in Healthy Adults
Interventions: Dietary Supplement: Vitafusion Power C gummy; Dietary Supplement: Nature Made vitamin C tablet
Sponsors: Church & Dwight Company, Inc.; KGK Science Inc.
Completed - Condition: Healthy Volunteers
Interventions: Drug: Adalimumab 100 MG/ML [Humira]; Drug: AVT02 100MG/ML
Sponsor: Alvotech Swiss AG
Completed - Condition: Healthy Volunteers
Interventions: Drug: LY2484595 Reference Formulation (RF); Drug: LY2484595 spray-dried solid dispersion-propyl gallate (SDSD-PG)
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Intervention: Drug: Insulin Peglispro
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Subjects in Fasted and Fed State
Interventions: Drug: Dapagliflozin/metformin XR 5/500mg; Drug: Dapagliflozin/metformin XR 5/500 mg; Drug: Dapagliflozin/metformin XR 10/1000mg
Sponsor: AstraZeneca
Completed - Condition: Healthy Volunteers
Interventions: Drug: Nafithromycin; Drug: Placebo
Sponsor: Wockhardt
Completed - Condition: Healthy
Interventions: Drug: CS8080; Drug: Placebo
Sponsor: Daiichi Sankyo, Inc.
Completed - Condition: Healthy Volunteers
Interventions: Drug: Evacetrapib; Drug: Simvastatin; Drug: Atorvastatin
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Interventions: Drug: Placebo; Drug: LY3084077
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Intervention: Drug: [^14C]-LY3023703
Sponsor: Eli Lilly and Company
Terminated - Condition: Healthy Volunteer
Interventions: Drug: Gantenerumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Completed - Condition: Associative Memory in Healthy Subjects
Interventions: Device: Active tDCS; Device: Sham tDCS
Sponsor: The University of Texas at Dallas
Active, not recruiting - Condition: Bioequivalence of Vitamin D in Healthy Adults
Intervention: Dietary Supplement: vitamin D3
Sponsors: Church & Dwight Company, Inc.; Medical University of South Carolina
Completed - Condition: Healthy
Interventions: Drug: Ketamine and Org 25935; Drug: Placebo and Ketamine
Sponsors: Yale University; Organon
Active, not recruiting - Condition: Healthy Subjects
Interventions: Drug: E0302 SR1; Drug: E0302 SR3; Drug: E0302 SR2; Drug: E0302 IR
Sponsor: Eisai Co., Ltd.
Recruiting - Condition: Healthy
Interventions: Drug: BIBR 1048 MS; Drug: Placebo of BIBR 1048 MS
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy Volunteers: Asian, Non-Asian
Interventions: Drug: BGB-3111 (Arm A); Drug: Rifampin; Drug: BGB-3111 (Arm B); Drug: Itraconazole
Sponsor: BeiGene
Completed - Condition: Healthy Volunteers
Interventions: Drug: Placebo; Drug: LY3023703; Drug: Celecoxib
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Interventions: Drug: Ortho-Cyclen; Drug: Evacetrapib
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Interventions: Drug: AG-348; Drug: [13C6]AG-348
Sponsor: Agios Pharmaceuticals, Inc.
Completed - Condition: Healthy Volunteers
Interventions: Drug: Evacetrapib; Other: High-fat Meal
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers (Meningococcal Infection)
Interventions: Biological: Meningococcal polysaccharide (serogroups A,C,Y and W) tetanus toxoid conjugate vaccine (MenACYW conjugate vaccine); Biological: Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine (MENVEO®); Biological: Diphtheria, Tetanus, Acellular Pertussis, Poliovirus and Haemophilus b Vaccine; Biological: Pneumococcal 13-valent Conjugate Vaccine; Biological: Rotavirus Vaccine; Biological: Hepatitis B Vaccine; Biological: Measles, Mumps, and Rubella Virus Vaccine; Biological: Varicella Virus Vaccine
Sponsor: Sanofi Pasteur, a Sanofi Company
Recruiting - Condition: Healthy Volunteer
Interventions: Drug: Gantenerumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Completed - Condition: Japanese Healthy Adult Male Participants
Interventions: Drug: TAK-906; Drug: TAK-906 Placebo
Sponsor: Takeda
Completed - Condition: Healthy Volunteers
Interventions: Drug: LY3053102; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Intervention: Drug: 14C labeled PXL770
Sponsor: Poxel SA
Completed - Conditions: Healthy Participants; Narcolepsy
Interventions: Drug: TAK-925; Drug: Placebo
Sponsor: Takeda
Recruiting - Condition: Chronic Hepatitis B
Interventions: Drug: JNJ-440; Drug: Placebo
Sponsor: Alios Biopharma Inc.
Recruiting - Condition: Infections, Bacterial
Interventions: Drug: GSK1322322 Initial fit for purpose tablets; Drug: GSK1322322 over granulated tablets; Drug: GSK1322322 intended commercial tablets; Drug: Placebo tablets; Drug: 13C-GSK1322322 stable isotope powder; Drug: GSK1322322 for injection; Drug: Placebo injection
Sponsor: GlaxoSmithKline
Terminated - Condition: Healthy Subjects, Overactive Bladder
Interventions: Drug: Formulation 1 solabegron; Drug: Formulation 2 solabegron
Sponsor: Velicept Therapeutics, Inc.
Completed - Condition: QT/QTc Interval in Healthy Volunteers
Interventions: Drug: WCK 5222; Drug: IV placebo matched to WCK 5222 / Moxifloxacin IV solution; Drug: Moxifloxacin 400-mg
Sponsor: Wockhardt
Completed - Conditions: Overweight; Obesity; Pregnancy Complications
Intervention: Behavioral: Lifestyle intervention
Sponsor: Maastricht University Medical Center
Recruiting - Conditions: Overweight and Obesity; Balance; Distorted
Intervention: Diagnostic Test: Core Stability Assessment
Sponsors: Wafaa Mahmoud Amin; Cairo University
Completed - Condition: Healthy
Intervention: Drug: Phencynonate hydrochloride
Sponsor: PhytoHealth Corporation
Completed - Conditions: Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs); Healthy Participants
Interventions: Drug: Treatment A; Drug: Treatment B; Drug: Treatment C; Drug: Treatment D; Drug: Acetaminophen
Sponsor: AstraZeneca
Completed - Conditions: Pregnancy Related; Diet Modification
Interventions: Behavioral: CAMI-TPP; Behavioral: CAMI-Fitness
Sponsors: Columbia University; The Office of Adolescent Health, HHS; Centers for Disease Control and Prevention
Not yet recruiting - Condition: Healthy Volunteers
Interventions: Drug: LY3025876; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Volunteers
Intervention: Drug: LY2605541
Sponsor: Eli Lilly and Company
Completed - Condition: Keratoconjunctivitis
Interventions: Drug: PP-001; Other: Placebo
Sponsor: Panoptes Pharma GmbH
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: LY3023703; Drug: Placebo; Drug: Celecoxib
Sponsor: Eli Lilly and Company
Completed - Condition: Immune Thrombocytopenia Purpura
Interventions: Drug: MK-8723; Drug: Matching Placebo
Sponsor: Merck Sharp & Dohme Corp.
Completed - Condition: Healthy
Interventions: Drug: PF614; Drug: Oxycodone extended-release; Drug: Naltrexone Hydrochloride
Sponsors: Ensysce Biosciences; PRA Health Sciences
Completed - Condition: Healthy Subjects
Interventions: Drug: lemborexant; Drug: Loestrin; Drug: famotidine; Drug: fluconazole
Sponsors: Eisai Inc.; Purdue Pharma LP
Completed - Condition: Healthy Volunteers
Intervention: Drug: [^14C]-LY2835219
Sponsor: Eli Lilly and Company
Completed - Conditions: Healthy; Safety
Interventions: Drug: SAD: APX-115; Drug: SAD: Placebo; Drug: MAD: APX-115; Drug: MAD: Placebo; Other: Food effect: fasted and fed; Other: Metabolic probe with or without APX-115
Sponsor: Aptabio Therapeutics, Inc.
Completed - Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Elafin; Drug: Placebo
Sponsors: Roham T. Zamanian; Duke University; SRI International
Recruiting - Conditions: Healthy; Neck Pain
Interventions: Other: Injection of Isotonic saline; Other: Injection of NGF
Sponsor: Aalborg University
Recruiting - Conditions: Alzheimer's Disease; Healthy Volunteers
Interventions: Drug: BNC; Other: Placebo
Sponsor: National Institute on Aging (NIA)
Completed - Condition: Healthy Volunteers
Interventions: Other: Sausage: Triomeg; Other: Sausage: Control
Sponsors: Clemens von Schacky; Südbayerische Fleischwaren GmbH
Completed - Condition: Healthy Volunteers
Intervention: Device: Comparative standard echocardiography between two devices : Vivid 9 General Electric and Epiq 7 Philips
Sponsor: University Hospital, Clermont-Ferrand
Recruiting - Conditions: Healthy; Hepatitis, Chronic
Interventions: Drug: JNJ-56136379; Drug: Placebo
Sponsor: Janssen Sciences Ireland UC
Completed - Condition: HIV Infections
Intervention: Drug: GSK1265744 30mg
Sponsors: ViiV Healthcare; GlaxoSmithKline
Completed - Condition: Healthy Volunteers
Interventions: Drug: rifapentene (RPT); Drug: darunavir/cobicistat (DRV/c); Drug: Isoniazid (INH); Dietary Supplement: Pyridoxine
Sponsor: National Institutes of Health Clinical Center (CC)
Recruiting - Condition: Healthy
Intervention: Drug: X4P-001
Sponsors: X4 Pharmaceuticals; Covance
Terminated - Conditions: Healthy Volunteer - Complete; Cystic Fibrosis
Interventions: Drug: PTI-808; Drug: Placebo; Drug: PTI-428; Drug: PTI-801
Sponsor: Proteostasis Therapeutics, Inc.
Recruiting - Condition: Healthy Adult Immune Responses to Vaccine
Interventions: Biological: VRC-EBOMVA079-00-VP (MVA-EbolaZ); Biological: VRC-EBOADC069-00-VP (cAd3-EBO)
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed - Condition: Healthy
Interventions: Device: AL measurement; Device: OCT
Sponsor: Semmelweis University
Completed - Condition: Healthy
Intervention:
Sponsor: VA Office of Research and Development
Active, not recruiting - Conditions: Teen Pregnancy Prevention; Contraceptive Usage
Intervention: Behavioral: Healthy Families, Healthy Futures
Sponsors: Mathematica Policy Research, Inc.; The Office of Adolescent Health, HHS; Decision Information Resources, Inc.
Active, not recruiting - Condition: Otherwise Healthy Overweight or Obese
Interventions: Drug: PHP-303; Other: Placebo
Sponsor: pH Pharma
Recruiting - Condition: Healthy Subjects
Interventions: Drug: ACT-389949 40 mg; Drug: ACT-389949 200 mg; Drug: ACT-389949 800 mg; Drug: ACT-389949 (Group C1 dose to be selected); Drug: ACT-389949 (Group C2 dose to be selected); Drug: Placebo
Sponsor: Idorsia Pharmaceuticals Ltd.
Completed - Condition: Healthy Volunteer
Intervention:
Sponsor: National Institutes of Health Clinical Center (CC)
Completed - Condition: Chronic Kidney Disease Mineral and Bone Disorder
Intervention: Other: Phosphorus Absorption Test
Sponsor: Purdue University
Recruiting - Condition: Healthy Participants
Interventions: Drug: LY2584702 Reference Formulation; Drug: LY2584702 Test Formulation; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Safety and Tolerability
Interventions: Drug: GT-002; Drug: Placebo oral capsule
Sponsors: Gabather AB; Smerud Medical Research International AS
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: BAY1834845; Other: Matching Placebo; Drug: Midazolam
Sponsor: Bayer
Recruiting - Conditions: Relationship, Family; Substance Use; Parenting
Intervention: Behavioral: Within My Reach/ Within Our Reach
Sponsors: Phoenix House Foundation, Inc.; New York University
Recruiting - Condition: Safety and Tolerability in Healthy Volunteers
Intervention: Drug: NLY01
Sponsor: Neuraly, Inc.
Recruiting - Condition: Healthy
Intervention:
Sponsor: Nanomix
Completed - Condition: Healthy Male Subjects
Interventions: Drug: Exforge tab. 10/160mg; Drug: Lodivixx tab. 5/160mg
Sponsor: Hanlim Pharm. Co., Ltd.
Completed - Conditions: Fatigue; Stroke Sequelae
Intervention: Other: Low-level laser therapy
Sponsor: Universidade do Vale do Paraíba
Recruiting - Condition: Burns
Interventions: Other: Lactulose and Mannitol solution; Other: Sucralose
Sponsor: GlaxoSmithKline
Terminated - Condition: Pharmacokinetic Study in Healthy Male Volunteers
Interventions: Drug: Orvepitant; Drug: Itraconazole
Sponsor: Nerre Therapeutics Ltd.
Completed - Condition: Healthy
Interventions: Drug: CT-P16; Drug: EU-approved Avastin; Drug: US-licensed Avastin
Sponsor: Celltrion
Completed - Conditions: Hyperglycemia; Hyperlipidemia
Interventions: Drug: Olanzapine; Drug: Ziprasidone
Sponsors: Washington University School of Medicine; Pfizer
Completed - Condition: PCOS Disease
Intervention: Other: Androgen metabolism after starvation
Sponsor: University Hospital Inselspital, Berne
Recruiting - Condition: Experimental Pain in Healthy Human Subjects
Interventions: Device: 10 Hz tACS of the bilateral somatosensory cortex; Device: 10 Hz tACS of the prefrontal cortex; Device: 80 Hz tACS of the bilateral somatosensory cortex; Device: 80 Hz tACS of the prefrontal cortex; Device: Sham stimulation of the bilateral somatosensory cortex; Device: Sham stimulation of the prefrontal cortex
Sponsors: Technische Universität München; German Research Foundation
Recruiting - Conditions: Alteration of Cognitive Function; Hypoxia
Intervention: Other: 2-hour period of hypoxia
Sponsor: University Hospital, Lille
Recruiting - Condition: Healthy Participants
Interventions: Drug: LY2484595; Drug: Placebo; Drug: Ketoconazole
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy Adult Immune Responses to Vaccine
Intervention: Biological: VRC-EBOMAB092-00-AB (MAb114)
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting - Conditions: Renal Insufficiency; Healthy Volunteers
Intervention: Drug: P03277
Sponsor: Guerbet
Active, not recruiting - Conditions: Healthy; Frontotemporal Dementia
Interventions: Biological: AL001; Other: Placebo
Sponsor: Alector Inc.
Recruiting - Condition: Healthy Subjects
Interventions: Other: Grape juice R@isol; Other: Commercially-available grape juice
Sponsor: Centre Hospitalier Universitaire Dijon
Completed - Conditions: ADME; Healthy
Intervention: Drug: napabucasin
Sponsor: Boston Biomedical, Inc
Completed - Investigation of Dietary Absorptive Capacity of Fructans in Healthy Subjects - A Dose Response StudyCondition: Healthy Volunteers
Interventions: Dietary Supplement: Fructan - 7.5; Dietary Supplement: Fructan - 10; Dietary Supplement: Fructan - 12.5; Dietary Supplement: Fructan -- 5 grams
Sponsors: Augusta University; American Gastroenterological Association Foundation
Completed - Condition: COPD
Interventions: Drug: PT010; Drug: PT009; Drug: Symbicort Turbohaler
Sponsor: Pearl Therapeutics, Inc.
Completed - Condition: Healthy
Interventions: Drug: zolpidem hemitartarate 1.75 mg - Sequency 1; Drug: zolpidem hemitartarate 1.75 mg - Sequency 2
Sponsor: Biolab Sanus Farmaceutica
Completed - Conditions: Bioequivalence; Healthy
Intervention: Drug: Interferon Beta-1A
Sponsor: Cinnagen
Recruiting - Condition: Healthy
Intervention: Drug: calcium formate
Sponsors: University of Wisconsin, Madison; Nephro-Tech 1, LLC
Completed - Condition: Alcohol Use Disorder
Interventions: Drug: Nalmefene; Drug: Baclofen; Drug: Placebo Oral Capsule
Sponsor: Prof. Daniele Zullino
Recruiting - Condition: Healthy Volunteers (Meningococcal Infection)
Interventions: Biological: Meningococcal Polysaccharide (Serogroups A,C,Y and W) Tetanus Toxoid Conjugate vaccine MenACYW conjugate vaccine; Biological: Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine; Biological: Meningococcal Polysaccharide (serogroups A,C,Y and W-135) Diphtheria Toxoid Conjugate Vaccine; Biological: Diphtheria and Tetanus Toxoids and Acellular Pertussis, inactivated Poliovirus and Haemophilus b Conjugate Vaccine; Biological: Diphtheria and Tetanus Toxoids and Acellular Pertussis, Hepatitis B and Inactivated Poliovirus Vaccine; Biological: Haemophilus b Conjugate Vaccine; Biological: Pneumococcal 13-valent Conjugate Vaccine; Biological: Rotavirus Vaccine, Live, Oral, Pentavalent; Biological: Hepatitis B Vaccine; Biological: Measles, Mumps, and Rubella Virus Vaccine Live; Biological: Varicella Virus Vaccine Live
Sponsor: Sanofi Pasteur, a Sanofi Company
Recruiting - Conditions: Advanced Cancer; Healthy
Intervention:
Sponsor: University Health Network, Toronto
Completed - Condition: Healthy
Intervention: Drug: Ivermectin
Sponsor: University of Oxford
Not yet recruiting - Condition: Healthy Volunteers
Intervention: Drug: PF-04427429
Sponsor: Pfizer
Completed - Condition: Glaucoma, Open-Angle
Intervention: Diagnostic Test: Visual field testing
Sponsors: University Hospital Inselspital, Berne; University of Bern
Recruiting - Conditions: Healthy Subject; Intracranial Neoplasm; Recurrent Glioblastoma
Interventions: Drug: Fluorine F 18 DASA-23; Procedure: Positron Emission Tomography
Sponsor: Sanjiv Sam Gambhir
Recruiting - Conditions: Type 2 Diabetes Mellitus; Healthy Subjects
Intervention: Drug: sotagliflozin (SAR439954)
Sponsor: Sanofi
Completed - Conditions: Hepatitis B; Infectious Disease; Liver Diseases
Interventions: Drug: CRV431; Drug: Placebo; Drug: TDF
Sponsor: ContraVir Pharmaceuticals, Inc.
Active, not recruiting - Condition: Multiple Sclerosis
Interventions: Diagnostic Test: MEP using standard facilitation technique; Diagnostic Test: MEP using modified facilitation technique
Sponsor: University Hospital, Basel, Switzerland
Recruiting - Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Treprostinil Inhalation Powder
Sponsor: Mannkind Corporation
Completed - Condition: Healthy
Intervention: Other: The high PUFA diet group
Sponsor: Poznan University of Life Sciences
Recruiting - Condition: Asthma
Interventions: Drug: Salbutamol Sulphate 150mcg UD-DPI Blister(1.6% blend); Drug: Salbutamol Sulphate 200mcg UD-DPI Blister(1.6% blend); Drug: Salbutamol Sulphate 250mcg UD-DPI Blister(1.6% blend); Drug: Salbutamol Sulphate 200mcg UD-DPI Blister(1% blend); Drug: Salbutamol Diskus 200mcg Blister; Drug: Salbutamol MDI 100mcg; Drug: Salbutamol Sulphate UD-DPI Blister (selected from Part A); Drug: Salbutamol Sulphate 250mcg UD-DPI Blister (selected from Part A); Drug: Salbutamol Diskus 200mcg Blister without activated charcoal; Drug: Salbutamol Diskus 200mcg Blister with activated charcoal; Drug: Salbutamol MDI 100mcg without activated charcoal; Drug: Salbutamol MDI 100mcg with activated charcoal
Sponsor: GlaxoSmithKline
Completed - Conditions: Healthy; Psoriasis
Interventions: Drug: BI 730357; Drug: Placebo; Drug: Midazolam
Sponsor: Boehringer Ingelheim
Completed - Condition: Growth
Intervention: Other: Formula feeding regimen
Sponsors: Nestlé; Biofortis Mérieux NutriSciences
Recruiting - Condition: Focus of Study of Healthy Adults
Interventions: Drug: 15Nitrogen(15N)-labeled sodium nitrite; Drug: 15Nitrogen(15N)-labeled sodium nitrate
Sponsor: Gladwin, Mark, MD
Completed - Conditions: Immunosuppression; Healthy; Healthy Subjects
Intervention:
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Completed - Condition: Chronic Hepatitis B
Interventions: Drug: ABI-H2158; Drug: Placebo for ABI-H2158
Sponsor: Assembly Biosciences
Recruiting - Condition: Healthy Volunteers (Meningococcal Infection)
Interventions: Biological: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine MenACYW conjugate vaccine; Biological: Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine; Biological: Measles, Mumps, and Rubella Virus Vaccine Live; Biological: Varicella Virus Vaccine; Biological: Pneumococcal 13-valent Conjugate Vaccine; Biological: Diphtheria, tetanus, pertussis (acellular component), hepatitis B, poliomyelitis (inactivated), and Haemophilus influenzae type b conjugate vaccine; Biological: Diphtheria, Tetanus, Pertussis (Acellular, Component) Poliomyelitis (inactivated) Vaccine, and Haemophilus influenza type b Conjugate Vaccine; Biological: Hepatitis B Vaccine; Biological: Rotavirus Vaccine, Live, Pentavalent; Biological: Japanese encephalitis vaccine (live, attenuated)
Sponsor: Sanofi Pasteur, a Sanofi Company
Recruiting - Condition: Neuropathic Pain
Intervention: Device: Repetitive Transcranial Magnetic Stimulation (rTMS)
Sponsor: Hospices Civils de Lyon
Completed - Conditions: Hemodialysis; Healthy
Intervention: Drug: [14C] CR845
Sponsor: Cara Therapeutics, Inc.
Active, not recruiting - Condition: Healthy
Interventions: Biological: Imvanex; Biological: Shingrix; Biological: LPS; Biological: Candin
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Improve Healthy Ageing in Seniors; Prevent Disease at Older Age
Interventions: Drug: Vitamin D3; Drug: Omega 3 fatty acids; Procedure: Strength Home Exercise; Procedure: Flexibility Home Exercise
Sponsors: University of Zurich; Recruitment Partners; University of Geneva, Switzerland; University of Basel; University Hospital, Toulouse, France (Prof. Bruno Vellas, MD); Charite University, Berlin, Germany; Medical University Innsbruck; University of Coimbra, Portugal (Prof. José daSilva, MD); Other University Partners; University of Sheffield; University of Manchester, UK (Prof. David Felson, MD MPH); Max Rubner University, Germany (Prof. Bernhard Watzl, PhD); Technische Universität Dresden; Impact Partner; International Osteoporosis Foundation (IOF; Prof. John Kanis, MD); SME Partners; Ferrari Data Solution; Gut Pictures, Switzerland (Benno Gut; animated exercise video); NOVAMEN, France (Sandrine Rival; logistic management partner); Pharmalys, UK (Marieme Ba; monitoring partner); Industry Partners; DSM Nutritional Products (Dr. Elisabeth Stöcklin PhD, Dr. Manfred Eggersdorfer PhD); Nestlé (Michaela Höhne PhD, Irène Corthesy PhD); Roche Diagnostics; Funding within Framework 7 research program of the European Commission (project 278588); Further collaborators and advisors at website do-health.eu
Completed - Conditions: Stroke; Stroke, Acute; Healthy
Interventions: Other: Veridical Visual Feedback; Other: Augmented Visual Feedback; Other: Healthy Comparative Reaching Task
Sponsor: Shirley Ryan AbilityLab
Recruiting - Condition: Alzheimer Disease
Interventions: Other: Exposure to familiar songs; Other: Music Experience Questionnaire; Other: Implicit tasks memory; Other: Questionnaires
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Conditions: Dialysis; Healthy Subjects; Cytomegalovirus Infection
Interventions: Drug: ASP0113; Drug: Placebo
Sponsors: Astellas Pharma Global Development, Inc.; Vical
Completed - Condition: Healthy
Interventions: Drug: LY3372689; Drug: Placebo
Sponsor: Eli Lilly and Company
Active, not recruiting - Conditions: Healthy Adults; Atopic Dermatitis; Wearables; Sweat Sensor; Gas Sensor
Interventions: Device: Gas sensor; Device: Sweat Sensor
Sponsor: Northwestern University
Recruiting - Condition: Gastric Ulcer
Interventions: Drug: ATB-346 OR Placebo; Drug: Naproxen sodium
Sponsor: Antibe Therapeutics Inc.
Completed - Condition: Child Abuse
Interventions: Other: Assessment; Behavioral: Fostering Healthy Futures (FHF)
Sponsors: University of Colorado, Denver; National Institute of Mental Health (NIMH); The Kempe Foundation for the Prevention and Treatment of Child Abuse and Neglect
Active, not recruiting - Conditions: Healthy Volunteers; Hemophilia A
Intervention: Drug: Emicizumab
Sponsor: Hoffmann-La Roche
Completed - Conditions: Diabetes; Diabetes Mellitus, Type 2; Healthy
Interventions: Drug: semaglutide; Drug: placebo
Sponsor: Novo Nordisk A/S
Completed - Condition: Refractory Chronic Cough
Interventions: Drug: Gefapixant 100 mg; Drug: Placebo
Sponsor: Afferent Pharmaceuticals, Inc.
Completed - Condition: Deglutition Disorder
Intervention:
Sponsor: University of Nebraska
Completed - Conditions: Healthy Subjects; Rheumatoid Arthritis
Intervention: Other: [68Ga]Ga-DOTA-Siglec-9
Sponsor: Turku University Hospital
Active, not recruiting - Conditions: Healthy; Dermal Pharmacokinetic Measurement
Interventions: Procedure: Intravenous infusion of lidocaine; Drug: Lidocaine 2.5% and Prilocaine 2.5% cream", USP (2.5% lidocaine, 2.5% prilocaine, Actavis Pharma incorporated, USA); Drug: Lidocorit 2%-Ampullen" (Gebro Pharma Gesellschaft mit beschränkter Haftung, Austria); Device: Dermal open flow microperfusion; Device: Dermal Microdialysis; Procedure: Blood sampling in dermal sampling visit; Procedure: Blood sampling in clearance visit
Sponsor: Joanneum Research Forschungsgesellschaft mbH
Recruiting - Condition: Analgesia
Interventions: Drug: KP-1199; Drug: Placebo oral capsule; Drug: Oxycodone oral capsule
Sponsors: Kalyra Pharmaceuticals, Inc.; United States Department of Defense; PRA Health Sciences
Recruiting - Condition: Malaria
Intervention:
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - Conditions: Healthy; Atopic Dermatitis
Interventions: Drug: Crisaborole ointment 2%; Drug: Vehicle
Sponsor: Pfizer
Completed - Condition: Healthy Male Subjects
Intervention: Drug: [14C]-Omaveloxolone
Sponsor: Reata Pharmaceuticals, Inc.
Recruiting - Conditions: Systemic Lupus Erythematosus; Healthy Participants
Interventions: Drug: BMS-986165; Drug: Moxifloxacin; Other: Placebo
Sponsor: Bristol-Myers Squibb
Completed - Condition: Systemic Lupus Erythematosus
Interventions: Biological: AMG 570; Biological: AMG 570 Matching Placebo
Sponsor: Amgen
Completed - Condition: Alzheimer Disease
Interventions: Other: Traditional Proton fMRI; Other: Hyperpolarized Xenon-129 fMRI; Drug: Hyperpolarized Xenon-129; Device: 1H-129Xe Dual-Tuned Quadrature Head Coil
Sponsors: Thunder Bay Regional Research Institute; Lakehead University; Thunder Bay Regional Health Sciences Centre
Recruiting - Condition: Diet Modification
Interventions: Behavioral: Healthy Feeding, Healthy Eating; Behavioral: Reading Readiness
Sponsors: University of Rhode Island; Brown University; University of Connecticut
Not yet recruiting - Condition: Healthy Volunteer
Interventions: Other: Healthy volunteers; Device: MRI
Sponsor: University Hospital, Grenoble
Terminated - Conditions: Healthy Subjects; PK/PD
Interventions: Drug: Vicagrel 6mg; Drug: Clopidogrel 75mg
Sponsor: Jiangsu vcare pharmaceutical technology co., LTD
Recruiting - Conditions: Safety; Healthy Subjects
Interventions: Drug: MEDI9314; Drug: placebo
Sponsor: MedImmune LLC
Completed - Condition: Bone Marrow Stromal Cells
Intervention:
Sponsor: National Institutes of Health Clinical Center (CC)
Completed - Condition: Influenza
Interventions: Biological: VRC-FLUNPF081-00-VP (HA-F A/Sing); Biological: VRC-FLUDNA082-00-VP (DNA A/Sing)
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting - Conditions: Healthy Volunteers; hATTR Amyloidosis
Interventions: Drug: ION-TTR-LRx; Drug: Placebo
Sponsor: Ionis Pharmaceuticals, Inc.
Recruiting - Condition: Malaria
Intervention:
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); University of Bamako
Recruiting - Conditions: Phenylketonuria; Healthy
Interventions: Drug: SYNB1618; Drug: Placebo
Sponsor: Synlogic
Recruiting - Condition: Healthy Subjects
Interventions: Drug: LEM5; Drug: LEM10; Drug: ZOL; Drug: PBO
Sponsors: Eisai Inc.; Purdue Pharma LP
Completed - Condition: Healthy
Interventions: Drug: GLPG3312 IR; Drug: Placebo; Drug: GLPG3312 MR; Drug: GLPG3312 FE MR
Sponsor: Galapagos NV
Recruiting - Conditions: Healthy Volunteer; Cystic Fibrosis
Interventions: Drug: PTI-801; Drug: Placebo; Drug: PTI-808
Sponsor: Proteostasis Therapeutics, Inc.
Recruiting - Conditions: Physical Activity; Sedentary Behaviors; Dietary Habits; Obesity
Intervention: Behavioral: Educational program for 2 months
Sponsor: King Abdullah International Medical Research Center
Completed - Condition: H1N1 Influenza Healthy Volunteers
Interventions: Biological: CR6261; Biological: Placebo
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed - Conditions: Pharmacokinetics; Healthy Volunteers
Interventions: Drug: BTA-C585 oral capsules; Drug: BTA-C585 matching placebo
Sponsor: Biota Pharmaceuticals, Inc.
Completed - Conditions: Rheumatoid Arthritis; Psoriasis; Ankylosing Spondylitis; Inflammatory Bowel Diseases; Nonalcoholic Steatohepatitis
Interventions: Drug: BMS-986251; Other: Placebo
Sponsor: Bristol-Myers Squibb
Terminated - Condition: Upper Respiratory Tract Infection
Intervention: Biological: RSV A2
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed - Conditions: Hyperglycemia, Postprandial; Healthy
Interventions: Dietary Supplement: Enriched pomegranate juice; Dietary Supplement: Placebo beverage
Sponsor: University of Leeds
Recruiting - Condition: Neurodegenerative Diseases
Intervention: Genetic: Study of Neurodegenerative Diseases Induced Stem Cells
Sponsors: Neuromed IRCCS; San Raffaele University Hospital, Italy
Not yet recruiting - Condition: Family Relations
Intervention: Behavioral: Elevate
Sponsors: University of Georgia; Department of Health and Human Services
Withdrawn - Conditions: Gestational Mothers; Weight Gain
Intervention: Behavioral: Mobile phone based intervention
Sponsor: Karolinska Institutet
Recruiting - Conditions: Pharmacokinetics; Healthy Volunteers
Interventions: Drug: BTA-C585 oral capsules; Drug: BTA-C585 matching placebo
Sponsor: Biota Pharmaceuticals, Inc.
Completed - Condition: Alzheimer's Disease, Healthy Volunteer
Interventions: Drug: [11C]RO6924963; Drug: [11C]RO6931643; Drug: [18F]RO6958948
Sponsor: Hoffmann-La Roche
Completed - Conditions: Diabetes; Healthy
Interventions: Drug: semaglutide; Drug: Omeprazole
Sponsor: Novo Nordisk A/S
Completed - Conditions: Nocturnal Eating-Drinking Syndrome; Healthy
Intervention:
Sponsor: University of Pennsylvania
Recruiting - Conditions: Congenital Bleeding Disorder; Haemophilia A; Healthy
Intervention: Drug: NNC172-2021
Sponsor: Novo Nordisk A/S
Terminated - Condition: Hepatitis C
Interventions: Biological: ChAd3-hliNSmut; Biological: MVA-hliNSmut
Sponsors: University of Oxford; Oxford University Hospitals NHS Trust; ReiThera Srl; European Commission; GlaxoSmithKline
Recruiting - Condition: Chronic Hepatitis B
Interventions: Drug: ABI-H0731; Drug: Placebo for ABI-H0731; Drug: Entecavir; Drug: Tenofovir disoproxil fumarate; Drug: Pegasys; Drug: Nucleos(t)ide
Sponsor: Assembly Biosciences
Completed - Condition: Healthy
Intervention: Drug: FP-025 (MMP-12 inhibitor)
Sponsor: Foresee Pharmaceuticals Co., Ltd.
Completed - Condition: Healthy Participants
Interventions: Drug: Lorcaserin manufactured at Zofingen; Drug: Lorcaserin manufactured at Kawashima
Sponsor: Eisai Inc.
Completed - Condition: Marburg Virus Disease
Intervention: Biological: cAd3-Marburg vaccine
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); US Military HIV Research Program
Recruiting - Conditions: Healthy Volunteers; Breast Cancer, Metastatic
Intervention: Diagnostic Test: Blood draw
Sponsor: Angle plc
Active, not recruiting - Condition: Healthy
Interventions: Biological: Ad26.Mos.HIV; Biological: Clade C gp140; Drug: Placebo
Sponsor: Janssen Vaccines & Prevention B.V.
Completed - Condition: Alzheimer Disease
Interventions: Drug: JNJ-63733657; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Emotional Stress
Intervention: Other: adapted STMST
Sponsors: NIZO Food Research; Procter and Gamble
Completed - Condition: Healthy
Interventions: Biological: LY3462817 IV; Biological: LY3462817 SC; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Condition: Overweight/Obesity
Interventions: Behavioral: Website and pedometer intervention; Other: Control
Sponsor: University of Bath
Completed - Condition: Food Effect of Fruquintinib in Health Subjects
Intervention: Drug: fruquintinib
Sponsor: Hutchison Medipharma Limited
Completed - Condition: Healthy
Interventions: Drug: SCT630; Drug: adalimumab-EU source
Sponsor: Sinocelltech Ltd.
Not yet recruiting - Condition: Healthy
Interventions: Biological: MVA-BN-Filo; Biological: Ad26.ZEBOV; Biological: Placebo
Sponsor: Janssen Vaccines & Prevention B.V.
Completed - Conditions: Healthy; Atopic Dermatitis
Interventions: Drug: MOR106; Drug: Placebo
Sponsor: Galapagos NV
Recruiting - Condition: Healthy
Interventions: Drug: LY3154207; Drug: [14C]-LY3154207
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: LY3451838; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Conditions: Phase 1; Bioequivalence
Intervention: Drug: Etanercept
Sponsor: AryoGen Pharmed Co.
Completed - A Thorough QTc Evaluation of the Effect of Semaglutide on Cardiac Repolarisation in Healthy SubjectsConditions: Diabetes; Healthy
Interventions: Drug: semaglutide; Drug: placebo; Drug: moxifloxacin
Sponsor: Novo Nordisk A/S
Completed - Condition: Acute Myeloid Leukemia
Interventions: Biological: Blood sample; Biological: Bone marrow sample
Sponsor: University Hospital, Toulouse
Completed - Condition: Healthy
Interventions: Drug: DS-1971a; Drug: placebo
Sponsor: Daiichi Sankyo, Inc.
Completed - Condition: Healthy
Intervention: Biological: Ixekizumab
Sponsor: Eli Lilly and Company
Active, not recruiting - Condition: Healthy
Interventions: Drug: SYNT001; Drug: Placebo
Sponsor: Syntimmune, Inc.
Completed - Condition: Healthy
Interventions: Drug: BI 690517; Drug: Placebo
Sponsor: Boehringer Ingelheim
Completed - Condition: Tuberculosis
Intervention: Drug: PA-824
Sponsor: Global Alliance for TB Drug Development
Completed - Condition: Healthy
Interventions: Behavioral: Yoga; Behavioral: Quiet Rest
Sponsor: University of Wisconsin, Madison
Completed - Condition: Healthy
Interventions: Drug: LY3502970; Drug: Placebo
Sponsor: Eli Lilly and Company
Not yet recruiting - Condition: Child Obesity
Interventions: Behavioral: FUNPALs Playgroup; Behavioral: Healthy Toddler Parent Group
Sponsor: University of Houston
Active, not recruiting - Condition: Healthy
Interventions: Drug: LY3200882; Drug: Itraconazole
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Intervention: Biological: Ixekizumab
Sponsor: Eli Lilly and Company
Active, not recruiting - Condition: Healthy
Interventions: Drug: Clinical Center Reference Endotoxin (CCRE); Drug: Normal saline
Sponsors: University of North Carolina, Chapel Hill; Environmental Protection Agency (EPA); RTI International; United States Department of Defense
Recruiting - Conditions: Healthy Volunteers; Breast Cancer
Intervention: Biological: [131I]-SGMIB Anti-HER2 VHH1
Sponsor: Camel-IDS NV
Completed - Condition: Healthy
Intervention: Device: transcranial direct current stimularion
Sponsor: Centro Universitario La Salle
Recruiting - Condition: Healthy
Interventions: Drug: LY900014 U-200; Drug: LY900014 U-100
Sponsor: Eli Lilly and Company
Completed - Conditions: Diet, Healthy; Health Risk Behaviors
Interventions: Other: Food coupons; Other: Nutrition skill-building
Sponsors: University of Calgary; Canadian Institutes of Health Research (CIHR); British Columbia Farmers' Market Nutrition Coupon Program
Not yet recruiting - Condition: Health Promotion
Intervention: Behavioral: SHE Tribe
Sponsors: University of North Texas Health Science Center; YMCA of Metropolitan Fort Worth; National Institute on Minority Health and Health Disparities (NIMHD)
Recruiting - Conditions: Healthy Male Subjects; Cardiovascular Disease
Interventions: Drug: AZD5718 oral suspension crystalline form (1 to 100 mg/mL) (Part A); Drug: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A); Drug: AZD5718 placebo oral suspension; Drug: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part B)
Sponsor: AstraZeneca
Completed - Condition: Healthy
Interventions: Drug: LY3316531; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: Verum; Drug: Placebo
Sponsor: Prof. Dominique de Quervain, MD
Completed - Condition: Healthy
Interventions: Device: Inspiratory muscle training; Other: Diaphragmatic breathing
Sponsor: Dokuz Eylul University
Completed - Condition: Healthy
Interventions: Drug: LY3314814; Drug: [13C415N3] LY3314814
Sponsors: Eli Lilly and Company; AstraZeneca
Completed - Condition: Healthy
Interventions: Drug: Escitalopram; Drug: Placebo oral capsule
Sponsor: University Hospital, Basel, Switzerland
Not yet recruiting - Condition: Healthy
Intervention: Drug: PT2977
Sponsor: Peloton Therapeutics, Inc.
Completed - Condition: Healthy
Intervention: Drug: CTP-543
Sponsor: Concert Pharmaceuticals
Active, not recruiting - Condition: Healthy
Interventions: Drug: LY3463251; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Condition: Healthy
Interventions: Drug: PRIC; Drug: Pranlukast hydrate
Sponsor: SamA Pharmaceutical Co., Ltd
Not yet recruiting - Conditions: Parkinson Disease; Healthy
Interventions: Other: Parkinson's disease patients; Other: No drug
Sponsor: Universidade Federal de Pernambuco
Recruiting - Condition: Healthy
Interventions: Dietary Supplement: Multivitamin; Dietary Supplement: Placebo
Sponsors: Do Vitamins Inc.; Nutrasource Diagnostics Inc.
Completed - Condition: Healthy
Interventions: Drug: Tirzepatide; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Dietary Supplement: Control; Dietary Supplement: Prebiotic
Sponsors: University of Calgary; General Mills Inc.
Active, not recruiting - Condition: Healthy
Interventions: Drug: LY3074828; Device: PFS; Device: AI
Sponsor: Eli Lilly and Company
Recruiting - Condition: Healthy
Intervention:
Sponsor: Scripps Translational Science Institute
Recruiting - Condition: Healthy
Interventions: Drug: Baricitinib suspension; Drug: Baricitinib tablet
Sponsor: Eli Lilly and Company
Completed - Condition: Depressive Disorder
Intervention: Drug: Paroxetine CR and Paroxetine IR
Sponsor: GlaxoSmithKline
Completed - Condition: Healthy
Intervention: Dietary Supplement: Arctigenin
Sponsors: University of California, Los Angeles; Charles Drew University of Medicine and Science
Not yet recruiting - Condition: Healthy
Interventions: Drug: LY3375880; Drug: Buffer Matrix (No LY3375880); Device: Autoinjector (AI); Device: Manual Syringe
Sponsor: Eli Lilly and Company
Recruiting - Condition: Healthy
Intervention: Biological: LY3074828
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Intervention: Device: No intervention
Sponsor: Arkansas Children's Hospital Research Institute
Active, not recruiting - Condition: Healthy
Interventions: Drug: Dulaglutide (Reference); Drug: Dulaglutide (Test)
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: Lanabecestat; Drug: Oral Contraceptive
Sponsors: Eli Lilly and Company; AstraZeneca
Withdrawn - Condition: Healthy
Interventions: Other: Postabsorptive; Other: Postprandial; Procedure: Immobilisation
Sponsor: University of Exeter
Recruiting - Condition: Healthy
Interventions: Drug: Aramchol; Drug: Midazolam; Drug: Atorvastatin
Sponsors: Galmed Pharmaceuticals Ltd; Hammersmith Medicines Research; Analyst Research Laboratories; Alderley Analytical; Diamond Pharma Services Regulatory Affairs Consultancy
Completed - Condition: Healthy Participants
Interventions: Other: Standard mixed breakfast meal; Other: SmartBar™
Sponsors: Kristine Færch; University of Copenhagen; iMotions A/S; University of Leeds; Aalborg University Hospital
Recruiting - Condition: Healthy
Interventions: Drug: BI 730357; Drug: BI 730357 mixed with [C-14] BI 730357 BS
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Drug: BI 425809; Drug: BI 425809 mixed with [C-14]-BI 425809
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Other: Unstable; Other: Stable
Sponsor: University of Valencia
Completed - Condition: Healthy
Interventions: Combination Product: Janumet XR tablet 100/1000 mg; Combination Product: GLH1SM tablet 100/1000 mg
Sponsor: GL Pharm Tech Corporation
Enrolling by invitation - Condition: Healthy
Interventions: Drug: BI 1358894; Drug: Itraconazole
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy
Interventions: Drug: BI 1291583; Drug: Itraconazole
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Healthy
Interventions: Biological: LY3074828; Drug: LY3074828; Device: Auto-injector (AI); Device: Prefilled syringe (PFS)
Sponsor: Eli Lilly and Company
Completed - Conditions: Trauma; Complications; Multiple Organ Failure
Interventions: Other: Traumatized population; Other: Healthy Volunteers
Sponsors: University of Florida; National Institutes of Health (NIH); National Institute of General Medical Sciences (NIGMS); Massachusetts General Hospital
Active, not recruiting - Condition: Healthy
Interventions: Combination Product: Janumet XR tablet 100/1000 mg; Combination Product: GLH1SM tablet 100/1000 mg
Sponsor: GL Pharm Tech Corporation
Completed - Condition: Healthy
Interventions: Drug: BMS-986205; Drug: omeprazole
Sponsor: Bristol-Myers Squibb
Not yet recruiting - Condition: Healthy
Intervention: Drug: 1 µCi of 14C-AAI101 + 500 mg AAI101
Sponsor: Allecra
Completed - Condition: Healthy
Interventions: Drug: BI 730357; Drug: Itraconazole
Sponsor: Boehringer Ingelheim
Completed - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: CCI15106; Drug: Placebo
Sponsor: GlaxoSmithKline
Completed - Condition: Healthy Subjects
Intervention:
Sponsors: Örebro University, Sweden; Region Örebro County
Active, not recruiting - Condition: Healthy
Intervention: Drug: BI 894416
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Other: 5-13C-Glutamine; Other: Bone marrow aspiration
Sponsor: Mayo Clinic
Active, not recruiting - Conditions: Mental Stress; Hypertension; Diabetes
Interventions: Behavioral: Healthy community clinic NCD+MH; Behavioral: Healthy community clinic NCD
Sponsors: University of Illinois at Urbana-Champaign; Americares; Royal Health Awareness Society
Active, not recruiting - Condition: Healthy
Interventions: Drug: Lactose-free memantine; Drug: Memantine
Sponsor: H. Lundbeck A/S
Completed - Conditions: Healthy; Salivary Gland Disease
Intervention:
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR)
Completed - Condition: Healthy
Interventions: Drug: Itraconazole; Drug: BI 894416
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Biological: JNJ-67670187; Biological: Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Healthy
Interventions: Dietary Supplement: Low dose response efficacy of plant extracts; Dietary Supplement: Middle dose response efficacy of plant extracts; Dietary Supplement: High Dose response efficacy of plant extracts; Dietary Supplement: Placebo
Sponsor: University of Roehampton
Not yet recruiting - Condition: Healthy
Intervention: Procedure: Distraction thrust manipulation
Sponsor: Florida Gulf Coast University
Recruiting - Condition: Healthy
Interventions: Drug: Vortioxetine IV; Drug: Vortioxetine SLA; Drug: Vortioxetine SLB; Drug: Vortioxetine SLC
Sponsor: H. Lundbeck A/S
Recruiting - Condition: Healthy
Interventions: Drug: Relacorilant 350mg; Drug: Itraconazole; Drug: Relacorilant "higher dose"; Drug: Relacorilant "lower dose"
Sponsor: Corcept Therapeutics
Recruiting - Condition: Healthy
Intervention: Drug: BI 1291583
Sponsor: Boehringer Ingelheim
Completed - Condition: ALD - Alcoholic Liver Disease
Intervention: Other: Blood draw
Sponsor: The Cleveland Clinic
Recruiting - Condition: Healthy
Interventions: Drug: Bedaquiline; Drug: Clarithromycin
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Healthy
Intervention: Drug: BI 1323495,
Sponsor: Boehringer Ingelheim
Completed - Conditions: Prediabetic State; Diabetes Mellitus, Type 2; Cardiorespiratory Fitness; Inflammation; Exercise Test
Intervention: Diagnostic Test: Cardiorespiratory Fitness
Sponsor: Hacettepe University
Recruiting - Condition: Healthy
Interventions: Drug: BI 409306 (C-13/N-15); Drug: BI 409306
Sponsor: Boehringer Ingelheim
Completed - Condition: Healthy
Interventions: Other: Clinic Pilates Group; Other: Aerobic Exercise Group; Other: Control Group
Sponsors: Biruni University; Istanbul University
Completed - Condition: Healthy Participants
Interventions: Drug: BMS-986165; Drug: Active Pharmaceutical Ingredient
Sponsor: Bristol-Myers Squibb
Recruiting - Condition: Safety, Pharmacokinetics, Pharmacodynamics, Food Effect
Interventions: Drug: AZD7986, oral solution, 1 to 50 mg/mL; Drug: Placebo, oral solution
Sponsor: AstraZeneca
Completed - Condition: Healthy
Interventions: Drug: Lanabecestat; Drug: Rosuvastatin
Sponsors: Eli Lilly and Company; AstraZeneca
Completed - Condition: Balance Disorders
Intervention: Diagnostic Test: Reaction for gait perturbation
Sponsor: Barbara Łysoń
Completed - Condition: Ulcerative Colitis
Interventions: Drug: BBT-401-1S, Single dose; Drug: BBT-401-1S, Multiple doses; Drug: Placebo
Sponsors: Bridge Biotherapeutics, Inc.; KCRN Research, LLC
Completed - Condition: Healthy
Interventions: Drug: BI 1265162 (T1); Drug: BI 1265162 (T2); Drug: BI 1265162 (R); Drug: BI 1265162 (T3)
Sponsor: Boehringer Ingelheim
Recruiting - Conditions: Blood Pressure; Hypertension
Interventions: Behavioral: Multi-component education program on salt reduction; Behavioral: Generic healthy lifestyle program
Sponsors: Academia Cuf Descobertas; NOVA Medical School; Jeronimo Martins
Recruiting - Condition: Healthy Volunteers
Interventions: Drug: USB005 (aclerastide) Ophthalmic Solution; Drug: USB005 Ophthalmic Solution Placebo
Sponsors: US Biotest, Inc.; United States Department of Defense
Completed - Condition: Healthy
Interventions: Biological: MT-5625 low dose; Biological: MT-5625 middle dose; Biological: MT-5625 high dose; Biological: Rotarix; Biological: Placebo
Sponsor: Mitsubishi Tanabe Pharma Corporation
Active, not recruiting - Condition: Healthy
Interventions: Drug: Abemaciclib Capsules (Reference Formulation); Drug: Abemaciclib Tablet (Test Formulation)
Sponsor: Eli Lilly and Company
Completed - Conditions: Reliability, Validity of Measurement to Assess Lumbar Spine Motion; Comparison of Healthy Subjects and Low Back Pain Patients
Intervention:
Sponsor: Ruhr University of Bochum
Completed - Condition: Gastroesophageal Reflux
Intervention: Device: Bravo
Sponsor: Guy's and St Thomas' NHS Foundation Trust
Recruiting - Condition: Healthy
Intervention: Drug: Lanabecestat
Sponsors: Eli Lilly and Company; AstraZeneca
Completed - Condition: Retinal Blood Flow
Interventions: Drug: Dronabinol; Other: Placebo
Sponsor: Medical University of Vienna
Completed - Condition: Healthy
Intervention: Biological: Galcanezumab
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: vadadustat reference tablets; Drug: vadadustat test tablets
Sponsor: Akebia Therapeutics
Completed - Condition: Healthy Volunteers
Interventions: Drug: Fingolimod Reference Formulation; Drug: Fingolimod Test Formulation
Sponsors: Asofarma S.A.I. y C.; Zenith Technology Corporation Limited
Completed - Condition: Healthy Volunteers (HV)
Intervention: Drug: [18F]MNI-1054
Sponsor: Invicro
Completed - Condition: Healthy
Interventions: Drug: GLPG1690 film-coated tablets; Drug: [14C]-GLPG1690 solution for infusion; Drug: [14C]-GLPG1690 capsules
Sponsor: Galapagos NV
Completed - Condition: Healthy
Interventions: Drug: WCK 4873; Drug: Placebo Oral Tablet
Sponsor: Wockhardt
Completed - Condition: Healthy
Interventions: Drug: RDN-929; Drug: Placebo oral capsule; Drug: RDN-929 TBD dose
Sponsors: Rodin Therapeutics; QPS Netherlands B.V.
Completed - Condition: Healthy
Interventions: Drug: Lanabecestat; Drug: Dabigatran etexilate
Sponsors: Eli Lilly and Company; AstraZeneca
Completed - Condition: Optokinetic Nystagmus
Intervention: Device: CAVA
Sponsors: Emily Woodhouse; University of East Anglia; Medical Research Council
Recruiting - Condition: Healthy Volunteers
Intervention: Drug: ORIC-101
Sponsor: Oric Pharmaceuticals
Completed - Condition: Healthy
Interventions: Drug: PF-06865571 administered Day 7-14; Drug: PF-06865571 administered Day 1-14; Drug: PF-05221304 administered Day 1-14; Drug: PF-05221304 administered Day 7-14
Sponsor: Pfizer
Completed - Condition: Healthy
Interventions: Drug: BI 730357 (Test); Drug: BI 730357 (Reference)
Sponsor: Boehringer Ingelheim
Active, not recruiting - Condition: Healthy
Intervention: Procedure: LPS challenge
Sponsors: Fraunhofer-Institute of Toxicology and Experimental Medicine; Hannover Medical School
Completed - Condition: Healthy
Interventions: Drug: PSI-697; Drug: Placebo
Sponsor: Pfizer
Completed - Conditions: Rheumatic Diseases; Healthy Volunteers
Intervention:
Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - Condition: Healthy
Interventions: Drug: K-285; Drug: Indomethacin
Sponsor: Kowa Research Institute, Inc.
Completed - Condition: Healthy
Interventions: Drug: JNJ-61393215; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Completed - Conditions: Bioequivalence; Phase 1
Intervention: Drug: Adalimumab
Sponsor: Cinnagen
Completed - Conditions: COPD; COPD Exacerbation; COPD, Severe Early-Onset
Intervention: Diagnostic Test: Isolation of Circulating Pulmonary Cells in peripheral blood
Sponsors: Universidad de Granada; Hospital de Alta Resolucion de Loja. Agencia Sanitaria Hospital de Poniente; Genyo-CentroPfizer-UGR-Junta Andalucia de genomica e investigacion oncologica
Not yet recruiting - Condition: Healthy
Intervention: Drug: Evacetrapib
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: Galcanezumab; Drug: Placebo
Sponsor: Eli Lilly and Company
Completed - Condition: Healthy
Interventions: Drug: Lanabecestat; Drug: Warfarin
Sponsors: Eli Lilly and Company; AstraZeneca
Completed - Condition: Healthy
Interventions: Drug: BI 425809 (Treatment T1); Drug: BI 425809 (Treatment T2); Drug: BI 425809 (Treatment R)
Sponsor: Boehringer Ingelheim
Active, not recruiting - Condition: Healthy
Intervention: Drug: BI 655130
Sponsor: Boehringer Ingelheim
Active, not recruiting - Condition: Healthy
Interventions: Drug: Dextromethorphan HBr; Drug: GC4419
Sponsor: Galera Therapeutics, Inc.
Not yet recruiting
Clinical Trial Locations