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- Condition: Healthy Controls
Interventions: Drug: OLANZapine 2.5 MG; Drug: Placebo; Drug: Insulin Lispro 100 UNT/ML; Other: Saline
Sponsors: Centre for Addiction and Mental Health; University Health Network, Toronto
Not yet recruiting - Condition: Mitochondrial Biogenesis
Interventions: Other: BFR Exercise; Other: CTL Exercise
Sponsor: Queen's University
Recruiting - Condition: Bioequivalence
Interventions: Drug: Telmisartan; Drug: Micardis
Sponsors: Pharmtechnology LLC; Algorithme Pharma, An Altasciences Company
Recruiting - Condition: Cardiac Arrythmias
Intervention: Drug: Carbetocin
Sponsor: University of British Columbia
Not yet recruiting - Conditions: Physical Activity; Dietary Modification
Interventions: Behavioral: interactive sessions; Behavioral: American Cancer Society guidelines
Sponsor: University of Ottawa
Recruiting - Condition: Healthy
Intervention: Other: Dietary Intakes
Sponsors: The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)
Recruiting - Condition: Healthy
Intervention: Dietary Supplement: Dietary Intakes
Sponsor: The Hospital for Sick Children
Recruiting - Condition: Healthy
Intervention: Dietary Supplement: Creatine
Sponsor: Brandon University
Recruiting - Condition: Healthy Resistance-Trained Males
Interventions: Other: Animal Proteins (crossover); Other: Plant-based protein blends type 1 (crossover); Other: Plant-based protein blends type 2 (crossover); Other: Plant-based protein blends type 3 (crossover)
Sponsor: Danone North America
Recruiting - Condition: Quality of Life
Intervention: Behavioral: High-Intensity Interval Training (HIIT)
Sponsor: McMaster University
Recruiting - Conditions: Zika Virus Infection; Zika Virus Disease
Interventions: Biological: Zika Virus Immune Globulin (ZIKV-IG); Other: Placebo
Sponsor: Emergent BioSolutions
Recruiting - Condition: Delayed Type Hypersensitivity
Interventions: Drug: Prednisone; Drug: Placebo
Sponsor: Innovaderm Research Inc.
Recruiting - Conditions: Asthma; Cough
Interventions: Other: Mannitol; Drug: Salbutamol 5mg/mL; Other: Sodium Chloride 0.9% Inhl 3Ml
Sponsors: McMaster University; Pharmaxis; AllerGen NCE Inc.
Not yet recruiting - Condition: Infections, Meningococcal
Interventions: Biological: MenACWY liquid vaccine with approximately 30% MenA FS (GSK3536820A); Biological: Licensed GSK MenACWY vaccine (Menveo)
Sponsor: GlaxoSmithKline
Recruiting - Conditions: Obesity; Health Behavior; Child Behavior; Child Obesity; Nutrition Disorders; Body Weight
Intervention: Behavioral: Family Healthy Living
Sponsors: University of Victoria; Childhood Obesity Foundation
Recruiting - Conditions: Healthy; Females; Bone
Interventions: Behavioral: Resistance and Plyometric Exercise; Dietary Supplement: Carbohydrate (Maltodextrin powder mixed with water); Dietary Supplement: Skim Milk; Dietary Supplement: Creatine powder mixed with water
Sponsor: Brock University
Not yet recruiting - Conditions: Healthy; Frontotemporal Dementia
Interventions: Biological: AL001; Other: Placebo
Sponsor: Alector Inc.
Recruiting - Condition: Healthy Participants
Interventions: Drug: IONIS FXI-LRx; Drug: Placebo
Sponsor: Ionis Pharmaceuticals, Inc.
Recruiting - Condition: Healthy Ageing
Interventions: Other: Treatment cookies; Other: Control cookies
Sponsors: University of Manitoba; University of Southern Queensland; Advance Queensland; Nutrafruit Pty Ltd; Nature Pacific Pty Ltd
Recruiting - Conditions: Nutrition; Cognitive Change; Food Intake Control; Satiety
Interventions: Other: Control; Other: White chocolate; Other: Dark chocolate 1; Other: Dark chocolate 2
Sponsor: Ryerson University
Recruiting - Condition: Dietary Modification
Intervention: Dietary Supplement: High-Protein Diet
Sponsors: University of Alberta; Almased Wellness GmbH
Recruiting - Conditions: Aging; Cognitive Decline
Interventions: Behavioral: Goal Management Training; Behavioral: Memory & Aging Program; Behavioral: BrainHQ
Sponsors: Baycrest; Centre for Aging and Brain Health Innovation
Recruiting - Conditions: Overweight; Obesity
Intervention: Behavioral: Hockey FIT Program (Immediate Delivery)
Sponsors: Western University, Canada; Canadian Institutes of Health Research (CIHR)
Not yet recruiting - Condition: Low Back Pain
Interventions: Device: Real-time ultrasound imaging feedback; Device: PBU feedback
Sponsor: Université de Sherbrooke
Recruiting - Condition: Sarcopenia
Interventions: Drug: Creatine monohydrate; Drug: Maltodextrin Powder
Sponsor: University of Regina
Recruiting - Conditions: Healthy; Overweight and Obesity; Metabolic Syndrome; PreDiabetes; Diabetes; Overweight; Obesity; Dysglycemia; Cardiovascular Diseases; Cardiovascular Risk Factor; Hypertension
Interventions: Other: Sugar-sweetened beverage (SSB); Other: Non-nutritive sweetened beverages (NSB); Other: Water
Sponsors: University of Toronto; Canadian Institutes of Health Research (CIHR)
Recruiting - Conditions: Healthy; Osteo Arthritis Knee
Intervention: Drug: [Tc-99m]-RPI-T-087 Injection
Sponsor: Reiley Pharmaceuticals Inc.
Recruiting - Conditions: Spina Bifida; Cerebral Palsy; Health Behavior
Intervention: Behavioral: Solution-Focused Coaching in Pediatric Rehabilitation
Sponsors: Holland Bloorview Kids Rehabilitation Hospital; Laval University
Recruiting - Condition: Healthy
Intervention: Other: Leucine
Sponsors: The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)
Recruiting - Conditions: Postprandial Lipemia; Satiety
Interventions: Other: Emulsion with solid droplets; Other: Emulsion with liquid droplets
Sponsor: University of Guelph
Recruiting - Condition: Post-prandial Glycaemic Response
Interventions: Dietary Supplement: Untreated; Dietary Supplement: Heat treated with 0% moisture; Dietary Supplement: Heat treated with 10% moisture; Dietary Supplement: Wheat
Sponsors: St. Boniface General Hospital Research Centre; Agriculture and Agri-Food Canada; University of Manitoba; Saskatchewan Pulse Growers
Not yet recruiting - Condition: Healthy Volunteers
Intervention: Drug: ACE-2494 or placebo
Sponsor: Acceleron Pharma, Inc.
Recruiting - Conditions: Functional Constipation; Healthy
Interventions: Dietary Supplement: Actazin (green kiwi powder) High Dose; Dietary Supplement: Actazin (green kiwi powder) Low Dose; Dietary Supplement: Control Formula (Actazin green kiwi powder + PreticX prebiotic); Dietary Supplement: Livaux (gold kiwi powder) High Dose; Dietary Supplement: Livaux (gold kiwi powder) Low Dose; Dietary Supplement: Placebo (microcrystalline cellulose)
Sponsors: AIDP, Inc.; KGK Science Inc.
Recruiting - Conditions: Muscle Function, Mitochondrial Function; Overweight; Healthy Aging
Interventions: Dietary Supplement: AMAZ-02 Low dose; Dietary Supplement: AMAZ-02 High Dose; Dietary Supplement: Placebo
Sponsors: Amazentis SA; KGK Science Inc.
Recruiting - Condition: Cytomegalovirus Infections
Interventions: Biological: V160; Drug: Placebo
Sponsor: Merck Sharp & Dohme Corp.
Recruiting - Condition: MCT Oil Supplementation
Intervention: Dietary Supplement: MCT Oil Supplementation
Sponsor: University of British Columbia
Recruiting - Conditions: Asthma; Chronic Obstructive Pulmonary Disease; Bronchiectasis; Emphysema; Pulmonary Fibrosis; Bronchopulmonary Dysplasia; Alpha 1-Antitrypsin Deficiency; Sarcoidosis, Pulmonary
Intervention: Other: Hyperpolarized 129Xe MRI
Sponsors: McMaster University; St. Joseph's Healthcare Hamilton
Not yet recruiting - Condition: Healthy
Interventions: Dietary Supplement: MSG; Dietary Supplement: CHO; Dietary Supplement: Placebo A; Dietary Supplement: Placebo B
Sponsor: University of Waterloo
Recruiting - Condition: Healthy Men
Intervention: Dietary Supplement: Metabolic availability of lysine in sorghum
Sponsors: The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)
Recruiting - Condition: Pregnancy Related
Intervention: Dietary Supplement: Aromatic Amino Acid Intake
Sponsors: University of British Columbia; Canadian Institutes of Health Research (CIHR)
Recruiting - Conditions: Crohn's Disease; Ulcerative Colitis; Healthy Controls
Intervention:
Sponsors: The Hospital for Sick Children; Mount Sinai Hospital, New York; Crohn's and Colitis Foundation
Recruiting - Condition: Healthy
Interventions: Drug: Indoximod base formulation; Drug: Indoximod HCL (salt) formulation; Other: Placebo
Sponsor: NewLink Genetics Corporation
Recruiting - Condition: Chronic Pain
Intervention: Other: Conditioned pain modulation
Sponsors: Université de Sherbrooke; Canadian Institutes of Health Research (CIHR); Centre for Research of CHUS (CRCHUS); CIHR/SPOR - chronic pain network
Recruiting - Conditions: Physical Activity; Diet Modification
Interventions: Behavioral: High-Carbohydrate Sedentary; Behavioral: High-Carbohydrate Active; Behavioral: Low-carbohydrate Sedentary
Sponsors: University of British Columbia; Mitacs; CoreHealth Technologies Inc.
Recruiting - Condition: Healthy Men
Intervention: Dietary Supplement: Metabolic availability of lysine in millet
Sponsors: The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)
Recruiting - Condition: Healthy
Interventions: Other: White bread; Other: Baked potato with skin; Other: Mashed potatoes; Other: Fried French fries; Other: Meal skipping
Sponsor: Ryerson University
Recruiting - Condition: Healthy
Interventions: Other: White bread; Other: Baked potato with skin; Other: Mashed potato served hot; Other: Fried French fries; Other: Meal skipping
Sponsor: Ryerson University
Not yet recruiting - Conditions: Postpartum Blues; Healthy
Interventions: Dietary Supplement: Motherwell; Other: Placebo
Sponsor: Centre for Addiction and Mental Health
Not yet recruiting - Condition: Post-prandial Glycaemia
Interventions: Dietary Supplement: Whole yellow pea soup; Dietary Supplement: Split yellow pea soup; Dietary Supplement: Potato soup
Sponsors: St. Boniface General Hospital Research Centre; Agriculture and Agri-Food Canada; University of Manitoba
Recruiting - Conditions: Post-prandial Glycaemic Response; Satiety
Interventions: Dietary Supplement: Whole yellow pea chili; Dietary Supplement: Split yellow pea chili; Dietary Supplement: Rice chili
Sponsors: St. Boniface General Hospital Research Centre; Agriculture and Agri-Food Canada; University of Manitoba
Recruiting - Conditions: Post-prandial Glycaemic Response; Satiety
Interventions: Dietary Supplement: Whole pea muffins; Dietary Supplement: Split pea muffins; Dietary Supplement: Wheat muffins
Sponsors: St. Boniface General Hospital Research Centre; Agriculture and Agri-Food Canada; University of Manitoba
Recruiting - Conditions: Allergic Rhinitis; Allergic Rhinitis Due to Grass Pollen; Healthy Volunteers
Interventions: Biological: B244 suspension; Biological: Vehicle
Sponsors: AOBiome LLC; Orange County Research Center; Integrium
Recruiting - Condition: None (i.e. Healthy Volunteers)
Interventions: Drug: Levomilnacipran; Drug: Duloxetine; Drug: Placebos
Sponsors: University of Ottawa; Allergan
Recruiting - Condition: Heart Failure
Interventions: Drug: AMG 986 IV Dose Level A or matching Placebo; Drug: AMG 986 IV Dose Level B or matching Placebo; Drug: AMG 986 IV Dose Level C or matching placebo; Drug: AMG 986 IV Dose Level D or matching placebo; Drug: AMG 986 IV Dose Level E or matching Placebo; Drug: AMG 986 IV Dose Level F or matching Placebo; Drug: AMG 986 IV Dose Level G or matching Placebo; Drug: AMG 986 Oral Dose Level A or matching Placebo; Drug: AMG 986 Oral Dose Level B or matching Placebo; Drug: AMG 986 Oral Dose Level C or matching Placebo; Drug: AMG 986 Oral Dose Level D or matching Placebo; Drug: AMG 986 Oral Dose Level E or matching Placebo; Drug: AMG 986 Oral Dose Level F or matching Placebo; Drug: AMG 986 Oral Dose Regimen or matching placebo - R; Drug: AMG 986 Oral Dose Regimen or matching placebo - P
Sponsor: Amgen
Recruiting - Conditions: Healthy Volunteer - Complete; Cystic Fibrosis
Interventions: Drug: PTI-808; Drug: Placebo; Drug: PTI-428; Drug: PTI-801
Sponsor: Proteostasis Therapeutics, Inc.
Recruiting - Conditions: Healthy; Men
Intervention: Dietary Supplement: Metabolic availability of lysine in wheat
Sponsors: The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)
Recruiting - Conditions: Untrained; Healthy
Interventions: Behavioral: Resistance and Plyometric Exercise; Dietary Supplement: Greek Yogurt (0% Plain); Dietary Supplement: Placebo - Study Designed Supplement
Sponsor: Brock University
Recruiting - Condition: Type2 Diabetes
Interventions: Dietary Supplement: Diet; Other: cold exposure; Radiation: 18FDG; Radiation: 11C-acetate; Radiation: [3-3H]-glucose; Other: [U-13C]-palmitate; Other: 2H-Glycerol; Device: MRI/MRS; Device: Electromyogram (EMG); Device: DXA; Device: Indirect calorimetry
Sponsors: Université de Sherbrooke; McMaster University; University of Ottawa
Recruiting - Condition: Healthy Volunteers
Intervention: Diagnostic Test: Hyperpolarized Helium 3 Magnetic Resonance Imaging
Sponsors: Western University, Canada; London Health Sciences Centre
Recruiting - Condition: Healthy
Intervention: Dietary Supplement: MAG-EPA
Sponsors: SCF Pharma; Université du Québec à Rimouski
Recruiting - Conditions: Cardiovascular Risk Factor; Smoking; Diabetes Mellitus; Dyslipidemias; Hypertension; Physical Activity; Stress, Psychological
Intervention: Behavioral: Cardiovascular Assessment Screening Program (CASP)
Sponsor: Memorial University of Newfoundland
Recruiting - Condition: Healthy
Intervention: Other: dietary intakes
Sponsor: The Hospital for Sick Children
Recruiting - Conditions: Healthy Volunteer - Complete; Cystic Fibrosis
Interventions: Drug: PTI-801; Drug: Placebo; Drug: PTI-808
Sponsor: Proteostasis Therapeutics, Inc.
Recruiting - Condition: Gastric Distension
Intervention: Device: High-Flow Heated and Humidified Oxygen Therapy (HFHHNO)
Sponsors: University Health Network, Toronto; Kaiser Permanente
Recruiting - Condition: Healthy
Interventions: Other: Test GUM; Other: Standard GUM; Other: Cows' milk
Sponsors: Nestlé; University of British Columbia
Recruiting - Condition: Overweight
Interventions: Dietary Supplement: High protein, high fiber dietary supplement; Dietary Supplement: Placebo
Sponsors: Beachbody; KGK Science Inc.; Glycemic Index Laboratories, Inc; MB Clinical Research and Consulting LLC
Recruiting - Condition: Healthy
Intervention: Device: transcranial direct current stimulation
Sponsor: University of Manitoba
Recruiting - Condition: Healthy
Intervention: Other: varying protein intakes
Sponsor: The Hospital for Sick Children
Recruiting - Conditions: Obesity, Morbid; Insulin Resistance
Interventions: Biological: Fecal filtrate from 150 g stool from healthy lean donors; Biological: Fecal filtrate from 150 g of the recipient's own stool
Sponsors: Johane Allard; Canadian Institutes of Health Research (CIHR); MOUNT SINAI HOSPITAL; University of Toronto
Recruiting - Condition: Sinusitis
Intervention: Other: Probiotics
Sponsor: Probionase Therapies Inc.
Recruiting - Conditions: Consumer Behavior; Diet, Food, and Nutrition
Intervention: Other: Nutrition Rating Systems
Sponsors: University of Toronto; Heart and Stroke Foundation of Canada; Dietitians of Canada
Not yet recruiting - Conditions: Ulcerative Colitis; Crohn's Disease
Interventions: Drug: Placebo; Drug: UTTR1147A
Sponsor: Genentech, Inc.
Recruiting - Condition: Pregnancy
Intervention: Dietary Supplement: Phenylalanine intake
Sponsors: University of British Columbia; Canadian Institutes of Health Research (CIHR)
Recruiting - Condition: Alzheimer Disease
Interventions: Other: Traditional Proton fMRI; Other: Hyperpolarized Xenon-129 fMRI; Drug: Hyperpolarized Xenon-129; Device: 1H-129Xe Dual-Tuned Quadrature Head Coil
Sponsors: Thunder Bay Regional Research Institute; Lakehead University; Thunder Bay Regional Health Sciences Centre
Recruiting - Condition: Joint Disease
Interventions: Device: Group 1 (Medial-Pivot); Device: Group 2 (Posterior-Stabilized)
Sponsors: MicroPort Orthopedics Inc.; University of Ottawa; The Ottawa Hospital
Recruiting - Condition: Healthy Volunteers
Intervention: Other: Hyperpolarized Xenon MRI
Sponsors: Western University, Canada; London Health Sciences Centre
Recruiting - Condition: Healthy
Interventions: Other: Hyperpolarized Helium-3; Device: MRI
Sponsor: Western University, Canada
Recruiting - Condition: Healthy
Interventions: Dietary Supplement: 0g barley β-glucan no fibre; Dietary Supplement: 2g barley β-glucan; Dietary Supplement: 4g barley β-glucan; Dietary Supplement: 6g barley β-glucan; Dietary Supplement: 0g barley β-glucan with fibre
Sponsors: St. Boniface General Hospital Research Centre; Agriculture and Agri-Food Canada
Recruiting - Condition: Obsessive-Compulsive Disorder
Intervention: Drug: SSRIs
Sponsors: McMaster University; Hamilton Health Sciences Corporation
Recruiting - Condition: Healthy
Intervention:
Sponsor: The Hospital for Sick Children
Recruiting - Conditions: Stroke; Apoplexy; Cerebral Stroke; Cerebrovascular Accident; Cerebrovascular Accident, Acute; Cerebrovascular Apoplexy; Cerebrovascular Stroke; CVA; Stroke, Acute; Vascular Accident, Brain
Intervention: Behavioral: Healthy Lifestyle Training Program
Sponsors: University of British Columbia; Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation of Canada
Recruiting - Conditions: Excessive Weight Gain in Pregnancy as Antepartum Condition; Obesity; Weight Gain; Type 2 Diabetes
Intervention: Behavioral: Exercise and Nutrition Intervention
Sponsors: McMaster University; Dairy Farmers of Canada
Recruiting - Conditions: Pregnancy Complications; Weight Gain
Intervention: Behavioral: Structured + monitored nutrition and exercise intervention
Sponsors: McMaster University; Canadian Institutes of Health Research (CIHR); Agriculture and Agri-Food Canada; Dairy Farmers of Canada
Recruiting - Condition: Chronic Kidney Disease
Intervention: Dietary Supplement: Fructose
Sponsor: University of Calgary
Recruiting
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