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  • Conditions:   Lung Diseases;   Pulmonary Disease;   Cystic Fibrosis;   Cystic Fibrosis Lung;   Cystic Fibrosis Pulmonary Exacerbation;   Cystic Fibrosis With Exacerbation;   Respiratory Tract Disease;   Pulmonary Inflammation;   Multi-antibiotic Resistance;   Antibiotic Resistant Infection;   Lung Infection;   Lung Infection Pseudomonal;   Lung; Infection, Atypical Mycobacterium;   Burkholderia Infections;   Burkholderia Cepacia Infection;   Lung Inflammation
    Interventions:   Drug: Inhaled SNSP113;   Drug: Inhaled Placebo
    Sponsor:   Synspira, Inc.

  • Condition:   Heart Failure
    Intervention:   Device: Device Programming of the Boston Scientific Cardiac Resynchronization Therapy Defibrillator (CRT-D)
    Sponsors:   Boston Scientific Corporation;   ICON plc

  • Condition:   Dementia
    Interventions:   Drug: Xanamem™;   Drug: Placebo (for Xanamem™)
    Sponsors:   Actinogen Medical;   ICON Clinical Research

  • Conditions:   Low Grade Ovarian Serous Adenocarcinoma;   Micropapillary Serous Carcinoma;   Ovarian Serous Adenocarcinoma;   Primary Peritoneal Serous Adenocarcinoma;   Recurrent Ovarian Carcinoma;   Recurrent Primary Peritoneal Carcinoma
    Interventions:   Other: Laboratory Biomarker Analysis;   Drug: Letrozole;   Drug: Paclitaxel;   Drug: Pegylated Liposomal Doxorubicin Hydrochloride;   Other: Pharmacological Study;   Other: Quality-of-Life Assessment;   Drug: Tamoxifen Citrate;   Drug: Topotecan Hydrochloride;   Drug: Trametinib
    Sponsor:   National Cancer Institute (NCI)

  • Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
    Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
    Sponsors:   New York University School of Medicine;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University

  • Condition:   Prostate Cancer
    Interventions:   Drug: Celecoxib;   Drug: Docetaxel;   Drug: Prednisolone;   Drug: ADT;   Drug: Zoledronic Acid;   Drug: Abiraterone;   Procedure: Orchiectomy;   Radiation: Radiotherapy to the prostate;   Drug: Enzalutamide;   Drug: Metformin;   Drug: Transdermal Oestradiol
    Sponsor:   Medical Research Council