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- Condition: Alzheimer Disease
Intervention: Drug: [C-11]PiB-PET/MRI
Sponsor: University of Alabama at Birmingham
Not yet recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Interventions: Behavioral: Memory Training; Behavioral: Kundalini yoga and meditation
Sponsor: University of California, Los Angeles
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Crenezumab (RO5490245)
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Active Treatment- CT1812 100 mg; Drug: Placebo; Drug: Active Treatment- CT1812 300 mg
Sponsor: Cognition Therapeutics
Recruiting - Conditions: Alzheimer Disease; Intestinal Microbiota
Intervention: Procedure: Fecal sample collection
Sponsor: Nantes University Hospital
Not yet recruiting - Conditions: Mild Cognitive Impairment; Prodromal Alzheimer's Disease
Interventions: Drug: Placebo Oral Tablet; Drug: AGB101 220 mg tablet
Sponsors: AgeneBio; National Institute on Aging (NIA)
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Device: Active Neuro RX Gamma device; Device: Sham Neuro RX Gamma device
Sponsors: Vielight Inc.; Canadian Centre for Aging and Brain Health Innovation
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Other: biopsies of colon
Sponsor: Nantes University Hospital
Not yet recruiting - Social Dancing Intervention for Older Adults at High Risk of Alzheimer's Disease and Other DementiasConditions: Alzheimer Disease; Dementia; Cognitive Decline; Cognitive Impairment; Dementia, Alzheimer Type
Interventions: Behavioral: Social Dancing; Behavioral: Treadmill Walking
Sponsor: Albert Einstein College of Medicine, Inc.
Not yet recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Interventions: Other: low carbohydrate/high fat diet; Other: low fat/high carbohydrate diet
Sponsors: Wake Forest University Health Sciences; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Mild Cognitive Impairment; Dementia
Interventions: Diagnostic Test: Non-invasive, multimodal retinal imaging; Diagnostic Test: Cerebral imaging; Diagnostic Test: Neuropsychiatric testing; Diagnostic Test: Venous blood sampling
Sponsor: Universitaire Ziekenhuizen Leuven
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: 18F-AV-1451
Sponsor: Avid Radiopharmaceuticals
Recruiting - Conditions: Mild to Moderate Dementia Due to Alzheimer's Disease; With or Without Coexisting Cerebrovascular Disease
Interventions: Drug: RPh201; Other: Placebo
Sponsor: Regenera Pharma Ltd
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease
Interventions: Biological: ABvac40; Biological: Placebo
Sponsor: Araclon Biotech S.L.
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment
Intervention: Diagnostic Test: [18F]flutemetamol PET scan
Sponsors: University of Utah; National Institutes of Health (NIH)
Not yet recruiting - Condition: APOE 4
Interventions: Drug: Levetiracetam 250 mg; Other: Placebo
Sponsors: Medical College of Wisconsin; National Institute on Aging (NIA)
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Drug: HTL0018318; Drug: Placebo
Sponsors: Heptares Therapeutics Limited; Allergan
Recruiting - Conditions: Sleep; Alzheimer Disease
Interventions: Behavioral: Behavioral sleep education; Behavioral: Education only
Sponsor: University of California, Los Angeles
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Other: Non-tailored intervention group; Other: Culturally tailored intervention group
Sponsors: University of Colorado, Denver; Washington State University; University of Arizona
Not yet recruiting - Conditions: Alzheimer Disease; Cholinesterase Inhibitors
Intervention: Drug: cholinesterase inhibitors (CI) (donepezil, galantamine or rivastigmine)
Sponsor: University Hospital, Bordeaux
Not yet recruiting - Conditions: Alzheimer Disease; Dementia Alzheimers; Dementia; Lewy Body Disease; Dementia, Lewy Body; Mild Cognitive Impairment
Intervention: Diagnostic Test: non-invasive retinal imaging
Sponsor: Universitaire Ziekenhuizen Leuven
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: TRx0237 8 mg/day; Drug: Placebo
Sponsor: TauRx Therapeutics Ltd
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Music lessons; Behavioral: Training intervention
Sponsors: University of Bergen; Uni Research; Bergen Municipality
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Gantenerumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Gantenerumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Alfoatirin® Tab. + Aripezil® Tab.; Drug: Aripezil® Tab.
Sponsor: Yuhan Corporation
Not yet recruiting - Condition: Mild Cognitive Impairment
Intervention: Other: Usual care setting
Sponsor: Eisai Korea Inc.
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Other: transdisciplinary approach; Other: multidisciplinary approach
Sponsors: University of Pittsburgh; Patient-Centered Outcomes Research Institute
Recruiting - Condition: Alzheimer's Disease or Related Disorder
Intervention: Behavioral: maintaining of occupational therapy
Sponsor: University Hospital, Bordeaux
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: VX-745; Drug: placebo
Sponsors: University Hospital, Toulouse; Fondation Plan Alzheimer
Not yet recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Donepezil TDS
Sponsor: Corium International Inc.
Recruiting - Condition: Behavior Disorders
Intervention:
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Donepezil TDS
Sponsor: Corium International Inc.
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment
Interventions: Behavioral: Routine care; Other: Coaching plus routine care
Sponsors: Hoag Memorial Hospital Presbyterian; Institute for Systems Biology
Recruiting - Conditions: Alzheimer Disease; Frontotemporal Dementia, Behavioral Variant
Intervention: Device: transcranial direct current stimulation (tDCS)
Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli
Recruiting - Condition: Alzheimer Disease
Intervention: Device: MHRC
Sponsors: Optina Diagnostics Inc.; McGill University; Polytechnique Montreal; Sunnybrook Health Sciences Centre
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: TEP
Sponsor: Immungenetics AG
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: COR388; Drug: Placebo
Sponsor: Cortexyme Inc.
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Transcranial Alternating Current Stimulation (tACS)
Sponsors: Beth Israel Deaconess Medical Center; Defense Advanced Research Projects Agency
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Device: Vielight Neuro Gamma; Other: Sham Vielight Neuro Gamma
Sponsor: University of California, San Francisco
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: neflamapimod; Other: placebo
Sponsors: EIP Pharma, LLC; Worldwide Clinical Trials; VU University Medical Center
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Montelukast new buccal film; Other: Placebo buccal film
Sponsor: IntelGenx Corp.
Not yet recruiting - Conditions: Cerebral Small Vessel Diseases; Stroke, Lacunar
Interventions: Drug: Isosorbide Mononitrate XL (ISMN); Drug: Cilostazol; Drug: ISMN XL and Cilostazol; Other: Neither ISMN nor cilostazol
Sponsors: University of Edinburgh; British Heart Foundation; University of Nottingham
Recruiting - Conditions: Pain; Alzheimer Disease
Interventions: Behavioral: Auricular Point Acupressure; Behavioral: Education Control
Sponsor: Johns Hopkins University
Not yet recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: Drug: Placebo; Drug: AVP-786
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Alzheimer Disease
Interventions: Device: GRASP DCE-MRI; Device: 3T Brain Scan
Sponsor: New York University School of Medicine
Not yet recruiting - Conditions: Traumatic Brain Injury; Alzheimer Disease; Veterans; Family Caregivers; Caregiver Burden; Quality of Life
Interventions: Other: ABC ANSWERS; Other: Control
Sponsors: Indiana University; Richard L. Roudebush VA Medical Center; Cleveland State University
Not yet recruiting - Condition: Gait Disorders, Neurologic
Intervention:
Sponsor: University Hospital, Strasbourg, France
Recruiting - Conditions: Cognitive Impairment; Apolipoprotein E, Deficiency or Defect of; Critical Illness; Burns; Young Adult
Intervention: Diagnostic Test: APOE genotyping
Sponsor: Chelsea and Westminster NHS Foundation Trust
Not yet recruiting - Condition: Mild Cognitive Impairment
Intervention: Other: No intervention
Sponsor: Sun Yat-sen University
Recruiting - Conditions: Alzheimer Disease; Cognitive Impairment, Mild
Interventions: Behavioral: Smartphone Personal Assistant; Behavioral: Implementation Intention
Sponsors: Baylor University; National Institute on Aging (NIA)
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Group-based Cognitive Behavioral Therapy (CBT); Behavioral: Phone-based Cognitive Behavioral Therapy (CBT)
Sponsors: Emory University; Alzheimer's Association
Recruiting - Condition: Major Depressive Disorder
Interventions: Drug: F-18 AV-45; Drug: F-18-THK-5351
Sponsor: Chang Gung Memorial Hospital
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: JNJ-63733657; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Alzheimer Disease
Interventions: Diagnostic Test: CSF drawing during spinal anaesthesia; Diagnostic Test: Fasting blood sample; Diagnostic Test: Lumbar puncture
Sponsor: University Hospital, Lille
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: LY3002813; Drug: LY3202626; Drug: Placebo (IV); Drug: Placebo (Oral)
Sponsor: Eli Lilly and Company
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: ID1201
Sponsor: IlDong Pharmaceutical Co Ltd
Recruiting - Conditions: Stroke; Parkinson Disease; Multiple Sclerosis; Oropharyngeal Dysphagia; Alzheimer Disease; Dementia
Intervention: Device: Dysphagia Detection System
Sponsors: Nestlé; Cytel Inc.; Regulatory and Clinical Research Institute Inc; Nestec Ltd.
Recruiting - Condition: Alzheimer's Disease
Interventions: Other: Multidimensional fragility index questionnaire RAI-Home Care; Other: Usual care
Sponsor: Assistance Publique Hopitaux De Marseille
Not yet recruiting - Conditions: Subjective Cognitive Decline; Preclinical Alzheimer's Disease
Intervention: Diagnostic Test: Neuropsychological scale
Sponsor: XuanwuH 2
Recruiting - Conditions: Lymphoma; Solid Malignancy; Alzheimer Disease; Myeloma
Interventions: Drug: PU-AD; Device: PET Scan; Other: Blood Draws
Sponsors: Samus Therapeutics, Inc.; Memorial Sloan Kettering Cancer Center; Weill Medical College of Cornell University; Rockefeller University
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: BIIB092; Drug: Placebo
Sponsor: Biogen
Recruiting - Condition: Alzheimer Disease
Intervention: Radiation: Low dose radiotherapy
Sponsor: Thomas Zilli
Recruiting - Condition: Alzheimer Disease
Interventions: Device: DBS of the fornix, power on; Device: DBS of the NbM, power on; Device: DBS of the fornix, power off; Device: DBS of the NbM, power off
Sponsors: Xuanwu Hospital, Beijing; Beijing Pins Medical Co., Ltd
Recruiting - Conditions: Cognitive Impairment; Alzheimer Disease
Interventions: Other: Relational care; Other: Hypno-analgesia
Sponsor: University Hospital, Montpellier
Not yet recruiting - Conditions: Brain Imaging; Mild Cognitive Impairment; Alzheimer Disease; Deep Brain Stimulation
Interventions: Device: Excitation; Device: Inhibition
Sponsor: University of California, Los Angeles
Not yet recruiting - Conditions: Dementia, Vascular; Alzheimer Dementia; Lewy Body Dementia With Behavioral Disturbance
Interventions: Device: Activlink insole; Other: Activlink Phone Application
Sponsors: University of Florida; National Institute on Aging (NIA); Aster Labs, Inc
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Other: Exposure to familiar songs; Other: Music Experience Questionnaire; Other: Implicit tasks memory; Other: Questionnaires
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Duke University
Recruiting - Conditions: Healthy; Mild Cognitive Impairment; Alzheimer Disease
Interventions: Device: real anodal transcranial direct current stimulation; Device: real transcranial alternating current stimulation; Device: sham transcranial electric current stimulation
Sponsor: University of Bern
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Other: Anodal tDCS; Other: Sham tDCS
Sponsors: University of Tromso; Helse Nord
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Neuro RX Gamma; Device: Sham
Sponsor: Vielight Inc.
Recruiting - Condition: Caregiver
Interventions: Behavioral: Intervention Condition; Behavioral: Control Condition
Sponsors: University of Miami; National Institute on Aging (NIA)
Recruiting - Condition: Brain Injuries, Traumatic
Intervention: Procedure: Acupuncture
Sponsor: China Medical University Hospital
Recruiting - Conditions: Alzheimer Disease; Dementia
Intervention: Behavioral: ACP Specialist Program
Sponsors: Indiana University; National Institute on Aging (NIA); Hebrew SeniorLife; Regenstrief Institute, Inc.
Not yet recruiting - Conditions: Living Alone; Alzheimer Disease; Mild Cognitive Impairment
Intervention:
Sponsor: University of California, San Francisco
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: 18F-AV-1451
Sponsor: Avid Radiopharmaceuticals
Recruiting - Conditions: Alzheimer's Disease (Incl Subtypes); Dementia; Mild Cognitive Impairment
Interventions: Behavioral: Dance Group; Behavioral: Non-Group Dance; Behavioral: Social Group; Behavioral: No Contact
Sponsors: Wake Forest University Health Sciences; National Center for Complementary and Integrative Health (NCCIH)
Recruiting - Conditions: Elderly Patients; Cognitive Disorder; Alzheimer Disease
Intervention: Diagnostic Test: "Antillanisée" Mini Mental State Examination (MMSEa)
Sponsor: University Hospital Center of Martinique
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: AGN-242071; Drug: Placebo; Drug: Donepezil; Drug: Memantine
Sponsor: Allergan
Not yet recruiting - Effect of IVIG on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer DiseaseCondition: Mild Cognitive Impairment
Intervention: Biological: Octagam 10%
Sponsor: Sutter Health
Not yet recruiting - Condition: Mild Cognitive Impairment
Interventions: Device: Transcutaneous vagal nerve stimulation; Device: Sham stimulation
Sponsors: University of Florida; Department of Health and Human Services; National Institute on Aging (NIA)
Recruiting - Conditions: PSP - Progressive Supranuclear Palsy; PD - Parkinson's Disease; AD - Alzheimer's Disease; ALS (Amyotrophic Lateral Sclerosis)
Intervention: Diagnostic Test: Pupillometry
Sponsors: Massachusetts General Hospital; NeurOptics Inc.; University of Toronto
Recruiting - Condition: Alzheimer Disease and Related Dementias
Interventions: Behavioral: SPIRIT-in person; Behavioral: SPIRIT-remote; Behavioral: Usual care
Sponsors: Emory University; National Institute on Aging (NIA)
Not yet recruiting - Condition: Primary Progressive Aphasia
Intervention: Behavioral: Evidence-Based Treatment
Sponsors: Northwestern University; National Institute on Aging (NIA)
Recruiting - Condition: Hypertension
Interventions: Drug: Standard Care; Drug: Intensive Treatment
Sponsors: University of Texas Southwestern Medical Center; Texas Health Resources; Michigan State University
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: Collaborative Dementia Care Program; Other: Screening Only
Sponsor: Indiana University
Not yet recruiting - Condition: Alzheimer Disease, Late Onset
Interventions: Diagnostic Test: CSF analysis; Radiation: Functional MRI
Sponsor: Ohio State University
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Dietary Supplement: Grape Powder; Dietary Supplement: Placebo Powder
Sponsors: University of California, Los Angeles; California Table Grape Commission
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: NDX-1017; Drug: Placebo
Sponsors: M3 Biotechnology, Inc.; Alzheimer’s Drug Discovery Foundation; Biotrial Inc.
Recruiting - Condition: Alzheimer Disease
Interventions: Other: Functionalities of the Lili Smart Solution activated; Other: Functionalities of the Lili Smart Solution non activated
Sponsors: Hospices Civils de Lyon; Lili smart
Recruiting - Conditions: Alzheimer Disease; Neurodegenerative Diseases
Intervention: Diagnostic Test: Cytology and Immunohistochemistry
Sponsor: University of Arkansas
Recruiting - Condition: Alzheimer Disease
Intervention: Device: Transcranial Alternating Current Stimulation (tACS)
Sponsor: Beth Israel Deaconess Medical Center
Recruiting - Condition: Alzheimer Disease
Interventions: Device: Deep brain stimulation (fornix); Device: Deep brain stimulation (Basal nucleus of Meynert)
Sponsor: Hospital San Carlos, Madrid
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: RO7105705; Drug: Placebo; Drug: [18F]GTP1
Sponsor: Genentech, Inc.
Recruiting - Condition: Alzheimer Disease
Intervention: Device: tDCS
Sponsor: Benjamin CALVET
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: 18F-AV-1451
Sponsor: Washington University School of Medicine
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Behavioral: ACT; Behavioral: Cycling Only; Behavioral: Cognitive Training Only; Behavioral: Stretching and Mental Stimulating Activities
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Rochester; Mayo Clinic; University of St Thomas
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Octohydroaminoacridine Succinate; Drug: Aricept; Drug: Placebos
Sponsors: Shanghai Mental Health Center; Changchun Huayang High-tech Co., Ltd; Jiangsu Sheneryang High-tech Co., Ltd
Recruiting - Conditions: Alzheimer Disease; Nurse Training
Intervention: Behavioral: RDAD Training
Sponsor: University of Washington
Not yet recruiting - Conditions: Alzheimer Disease; Herpes Simplex 1; Herpes Simplex 2
Interventions: Drug: Valacyclovir; Drug: Placebo
Sponsors: New York State Psychiatric Institute; National Institutes of Health (NIH); National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Salsalate; Drug: Placebo
Sponsor: Adam Boxer
Recruiting - Conditions: Alzheimer Disease; Sleep Apnea
Intervention: Diagnostic Test: PET Scan and nocturnal polysomnography
Sponsor: New York University School of Medicine
Recruiting - Condition: Dementia
Interventions: Behavioral: Old SCHOOL Hip-Hop; Behavioral: My Pyramid in Egypt
Sponsor: Columbia University
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Escitalopram Pill; Drug: Venlafaxine Pill; Drug: Placebo Oral Tablet
Sponsor: New York University School of Medicine
Recruiting - Condition: Cancer, Breast
Interventions: Behavioral: DECAD decision aid; Other: Home safety guide
Sponsor: Indiana University
Recruiting - Conditions: Alzheimer Disease; HIV
Intervention: Drug: F 18 T807
Sponsor: Washington University School of Medicine
Recruiting - Condition: Primary Progressive Aphasia With Suspected Alzheimer's Disease
Interventions: Drug: 18F-AV-1451; Device: PET
Sponsors: Northwestern University; National Institute on Aging (NIA)
Recruiting - Conditions: Glaucoma; Mild Cognitive Impairment; Glaucoma and Mild Cognitive Impairment; Healthy
Interventions: Device: Ocusweep test battery; Diagnostic Test: Neuropsychological test battery
Sponsors: Turku University Hospital; Ocuspecto Oy; European Commission
Recruiting - Conditions: Behavioral and Psychiatric Symptoms of Dementia; Dementia; Caregivers
Intervention: Other: Intervention with Home-Based Caregivers
Sponsors: University of Virginia; Carilion Clinic; North Carolina Agricultural and Technical State University
Recruiting - Condition: Alzheimer's Disease
Interventions: Other: Adapted Tango Dance; Behavioral: Educational lectures
Sponsor: Emory University
Recruiting - Conditions: Dementia; Parkinson; Altered Behavior in Alzheimer Disease; Demyelinating Autoimmune Diseases, CNS; Demyelinating Sensorimotor Neuropathy; Huntington Disease; Corticobasal Degeneration
Interventions: Procedure: Microcannula Harvest Adipose; Device: Centricyte 1000; Procedure: Sterile Normal Saline Infusion
Sponsors: Healeon Medical Inc; Global Alliance for Regenerative Medicine; Robert W. Alexander, MD, FICS; Regeneris Medical Inc
Recruiting - Condition: Dementia-related Psychosis
Interventions: Drug: Placebo; Drug: Pimavanserin 34 mg; Drug: Pimavanserin 20 mg
Sponsor: ACADIA Pharmaceuticals Inc.
Recruiting - Condition: Alzheimer Dementia
Intervention:
Sponsor: Assiut University
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Donepezil TDS; Drug: Aricept
Sponsor: Corium International Inc.
Recruiting - Conditions: Mild Dementia; Moderate Dementia
Intervention: Behavioral: iCST web-application
Sponsor: University of Nottingham
Not yet recruiting - Conditions: Sleep; Alzheimer Disease; Cognitive Impairment; Aging; CBT
Interventions: Behavioral: Sleep intervention; Behavioral: Placebo intervention
Sponsor: University of California, San Francisco
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: Rotigotine transdermal patch; Other: Placebo
Sponsor: I.R.C.C.S. Fondazione Santa Lucia
Recruiting - Condition: Alzheimer Disease; Prodromal
Interventions: Other: Regular health advice; Behavioral: Multidomain lifestyle; Dietary Supplement: Medical food
Sponsors: Karolinska Institutet; University of Eastern Finland; INSERM-University of Toulouse; Saarland University
Not yet recruiting - Conditions: Neurocognitive Disorder; Mild Cognitive Impairment; Alzheimer Dementia; Vascular Dementia; Age-related Cognitive Decline
Interventions: Diagnostic Test: Neurocognitive battery; Diagnostic Test: MRI; Biological: Blood tests; Diagnostic Test: EEG with event-related potential (ERP); Diagnostic Test: Amyloid PET CT
Sponsors: The University of Hong Kong; Dementias Platform UK
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: [18F]MNI-1020
Sponsor: Janssen Research & Development, LLC
Recruiting - Conditions: Dementia; Infection, Bacterial
Intervention: Behavioral: TRAIN-AD
Sponsor: Hebrew Rehabilitation Center, Boston
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Retinal Vascular
Intervention: Device: Retinal Imaging
Sponsor: Duke University
Recruiting - Conditions: Mild Cognitive Impairment; Prodromal Alzheimer's Disease; Mild Alzheimer's Disease
Interventions: Drug: Deferiprone 600mg delayed release tablets; Drug: Placebo Oral Tablet
Sponsor: Neuroscience Trials Australia
Recruiting - Condition: Alzheimer Disease
Intervention: Dietary Supplement: GRAPE granules
Sponsors: Dongzhimen Hospital, Beijing; Beijing Hospital; Chinese PLA General Hospital; Peking University Third Hospital
Recruiting - Conditions: Agitation in Patients With Dementia of the Alzheimer's Type; Alzheimer Disease; Agitation,Psychomotor
Interventions: Drug: AXS-05; Drug: Bupropion; Drug: Placebo
Sponsor: Axsome Therapeutics, Inc.
Recruiting - Conditions: Diet Modification; Cognitive Decline; Cognitive Change
Interventions: Other: Multicultural Healthy Diet; Other: Usual Diet plus Self-Care
Sponsors: Albert Einstein College of Medicine, Inc.; Penn State University; University of Pennsylvania; University of Minnesota - Clinical and Translational Science Institute; National Institute on Aging (NIA)
Not yet recruiting - Conditions: Healthy; Mild Cognitive Impairment; Alzheimer Disease
Interventions: Device: real anodal transcranial direct current stimulation (tDCS); Device: sham transcranial direct current stimulation (tDCS)
Sponsor: University of Bern
Recruiting - Conditions: Alzheimer Disease; Aging; MCI
Intervention: Device: TMS
Sponsors: Duke University; National Institute on Aging (NIA); National Institutes of Health (NIH)
Not yet recruiting - Conditions: Alzheimer's Disease (Incl Subtypes); Cognitive Impairment
Intervention: Behavioral: Enhanced psycho-education about dementia and caregiving
Sponsors: University of California, Davis; National Institute on Aging (NIA); Alzheimer's Association
Recruiting - Conditions: Alzheimer Dementia (AD); Vascular Dementia
Intervention: Behavioral: Vestibular Training (Intervention Group)
Sponsor: University Health Network, Toronto
Recruiting - Condition: Alzheimer Disease
Interventions: Other: serious games use; Other: usual care
Sponsor: Centre Hospitalier Universitaire de Nice
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Dietary Supplement: Challenge A - low calorie Ensure®; Dietary Supplement: Challenge B - Ensure® plus ketone esters (KE); Procedure: PET Scan; Behavioral: Cognitive Testing - FCSRT; Behavioral: Story Recall; Behavioral: BVRT; Behavioral: CogState One Card Learning
Sponsor: Wake Forest University Health Sciences
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Donepezil patch; Drug: aricept Tab
Sponsor: Icure Pharmaceutical Inc.
Recruiting - Conditions: Multiple Sclerosis; Parkinson Disease; Amyotrophic Lateral Sclerosis; Alzheimer Disease
Intervention: Procedure: lumbar puncture
Sponsors: Neuromed IRCCS; IRCCS Multimedica
Recruiting - Condition: Mild Alzheimer's Disease
Interventions: Drug: IONIS MAPTRx; Other: Placebo
Sponsor: Ionis Pharmaceuticals, Inc.
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Normal Saline 0.9%; Drug: GV1001 0.56 mg; Drug: GV1001 1.12 mg
Sponsor: GemVax & Kael
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: NP001; Drug: Placebo
Sponsors: Beau Nakamoto; Neuraltus Pharmaceuticals, Inc.
Recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: Memantine Hydrochloride
Sponsor: Wei Cuibai
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Biological: human umbilical cord blood derived mesenchymal stem cells; Other: Normal saline 2mL
Sponsor: Medipost Co Ltd.
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Lithium Carbonate; Drug: Placebo oral capsule
Sponsors: Ariel Gildengers; National Institute on Aging (NIA)
Recruiting - Condition: Osteoporosis
Intervention: Procedure: Hip bone sampling
Sponsor: Centre Hospitalier Universitaire de Nice
Recruiting - Conditions: Anticholinergics; Cognitive Function
Intervention:
Sponsors: Region Skane; Angelholm Hospital
Recruiting - Conditions: Alzheimer Disease; Cognitive Function
Interventions: Drug: Tandospirone Citrate; Drug: Donepezil Hydrochloride
Sponsor: Zhejiang Provincial People’s Hospital
Not yet recruiting - Conditions: Alzheimer Disease, Early Onset; Alzheimer Disease; Alzheimer Disease, Late Onset; Dementia, Alzheimer Type; Logopenic Progressive Aphasia; Primary Progressive Aphasia; Visuospatial/Perceptual Abilities; Posterior Cortical Atrophy; Executive Dysfunction; Corticobasal Degeneration; Ideomotor Apraxia
Intervention:
Sponsors: University of California, Los Angeles; National Institute on Aging (NIA); University of Southern California
Recruiting - Conditions: Alzheimer Disease; Alzheimer Disease, Late Onset; Memory Loss; Patient Education as Topic
Intervention: Behavioral: Web-based educational recommendations
Sponsor: Weill Medical College of Cornell University
Recruiting - Conditions: Dementia; Alzheimer Disease; Parkinson Disease; Lewy Body Disease; Parkinson-Dementia Syndrome; Frontotemporal Degeneration; Semantic Dementia; Progressive Nonfluent Aphasia; Progressive Supranuclear Palsy; Corticobasal Degeneration; Multiple System Atrophy; Mild Cognitive Impairment
Interventions: Diagnostic Test: Flutemetamol F18 Injection; Diagnostic Test: [18F]-RO6958948; Diagnostic Test: Elecsys (Roche) Abeta42, Ttau and Ptau; Diagnostic Test: Lumipulse (Fujirebio) Abeta42, Ttau and Ptau
Sponsors: Skane University Hospital; Lund University
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Prediabetic State
Intervention:
Sponsor: Wake Forest University Health Sciences
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease
Intervention:
Sponsor: Baylor Research Institute
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: CNP520 50mg; Drug: CNP520 15mg; Other: Placebo to CNP520
Sponsors: Novartis Pharmaceuticals; Amgen; Banner Alzheimer's Institute
Recruiting - Conditions: Dementia; Alzheimer Disease; Memory Loss
Intervention: Behavioral: psychoeducational skills training intervention
Sponsor: Arizona State University
Recruiting - Condition: Alzheimer Dementia
Intervention: Device: Immunoadsorption with Globaffin
Sponsor: University Medicine Greifswald
Recruiting - Condition: Mild Cognitive Impairment (MCI)
Intervention: Diagnostic Test: Diagnosis of MCI versus No MCI (SCI or healthy patient)
Sponsor: Assistance Publique Hopitaux De Marseille
Not yet recruiting - Condition: Alzheimer Disease
Intervention: Device: SONOCLOUD®
Sponsors: Assistance Publique - Hôpitaux de Paris; CarThera; BPIfrance
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: AstroStem; Other: Placebo-Control
Sponsor: Nature Cell Co. Ltd.
Recruiting - Conditions: Sedentary Lifestyle; Stress, Psychological
Intervention: Behavioral: Exergame Experience
Sponsors: Brandeis University; National Institute on Aging (NIA)
Recruiting - Condition: Dementia, Alzheimer Type
Interventions: Behavioral: ABC Clinical Program; Behavioral: HABC 2.0
Sponsors: Richard Holden; Indiana University
Not yet recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Chinese PLA General Hospital
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Crenezumab; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: [18F]THK-5351
Sponsor: Asan Foundation
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease; Vascular Dementia; Healthy Controls
Interventions: Other: Transcranial doppler ultrasonography; Other: Blood pressure monitoring; Other: Heart rate monitoring; Other: End tidal CO2 monitoring; Other: Addenbrooke's cognitive examination
Sponsor: University of Leicester
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Guanfacine; Drug: Placebo
Sponsor: Imperial College London
Not yet recruiting - Condition: Dementia
Interventions: Drug: Escitalopram; Drug: Placebo
Sponsors: JHSPH Center for Clinical Trials; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: S-equol; Other: Placebo
Sponsors: Russell Swerdlow, MD; Ausio Pharmaceuticals, LLC
Recruiting - Condition: Dementia Alzheimers
Intervention: Behavioral: Psychosocial caregiver intervention
Sponsors: University of California, Davis; University of South Carolina
Recruiting - Condition: Dementia
Intervention:
Sponsor: National Taiwan University Hospital
Recruiting - Condition: Alzheimer Disease
Intervention: Diagnostic Test: ADASCog
Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting - Conditions: Traumas, Brain; Alzheimer Disease; Dementia; Head Injury; Concussion, Brain; TBI
Interventions: Behavioral: Combined Aerobic and Resistance Exercise + Caregiver Skills Training; Behavioral: Stretching Balance and Flexibility + Caregiver Skills Training
Sponsors: Palo Alto Veterans Institute for Research; United States Department of Defense
Recruiting - Conditions: Delirium; Alzheimer Disease
Interventions: Behavioral: Physical Exercise Intervention; Behavioral: Cognitive Training Intervention; Behavioral: Stretching Control; Behavioral: Cognitive Control
Sponsor: Indiana University
Recruiting - Condition: PreDiabetes
Intervention: Behavioral: Diet and Exercise
Sponsor: University of Wisconsin, Madison
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: 11C-JNJ-63779586
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: Gabapentin Enacarbil; Drug: Placebo Oral Tablet
Sponsors: University of Texas at Austin; National Institute on Aging (NIA)
Recruiting - Conditions: Sleep; Sleep Disorders; Insomnia; Alzheimer's Disease
Interventions: Drug: Zolpidem; Drug: Zoplicone; Drug: Placebo
Sponsor: Brasilia University Hospital
Recruiting - Condition: Alzheimer's Disease; Dementia
Intervention: Other: HIGH and LOW meal ingestion
Sponsor: University of Washington
Recruiting - Conditions: Alzheimer Disease; Healthy Volunteers
Interventions: Drug: [18F] MNI-946; Drug: [18F]Florbetapir
Sponsor: Molecular NeuroImaging
Recruiting - Condition: Mild to Moderate Alzheimer's Disease
Interventions: Drug: 400mg LM11A-31-BHS; Drug: 800mg LM11A-31-BHS; Drug: Placebos
Sponsors: PharmatrophiX Inc.; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer Disease; White Matter Hyperintensities; Dementia; Aging
Interventions: Radiation: Florbetaben F18; Procedure: Transcranial Doppler
Sponsors: Columbia University; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: L-Serine; Other: Placebo Gummy
Sponsors: Dartmouth-Hitchcock Medical Center; Brain Chemistry Laboratories, Institute for Ethnomedicine
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment
Interventions: Drug: Nicotinamide; Drug: Placebo Comparator
Sponsor: University of California, Irvine
Recruiting - Conditions: Delirium; Cognitive Impairment; Alzheimer; Early Onset; Trauma; Polytrauma; Traumatic Brain Injury; ICU; Critical Illness
Intervention: Other: Non-interventional observational prospective cohort study
Sponsors: Vanderbilt University Medical Center; National Institutes of Health (NIH); National Institute of General Medical Sciences (NIGMS)
Recruiting - Condition: Frail Elderly
Intervention: Procedure: MRI and PET scan
Sponsors: University Hospital, Toulouse; MSDAVENIR
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: N-hydroxy-N'-phenyl-octanediamide (Vorinostat)
Sponsors: German Center for Neurodegenerative Diseases (DZNE); University Hospital, Bonn; University of Göttingen
Recruiting - Conditions: Alzheimer Disease; Healthy Volunteers; Progressive Supranuclear Palsy
Interventions: Drug: [18F]MNI-958; Drug: [18F]Florbetapir; Drug: DaTscan
Sponsor: Molecular NeuroImaging
Recruiting - Condition: Mild-moderate Alzheimer's Disease
Interventions: Drug: Donepezil; Drug: DHP1401; Drug: Placebo
Sponsor: Daehwa Pharmaceutical Co., Ltd.
Recruiting - Conditions: Elderly; Alzheimer Disease
Interventions: Procedure: Actigraphy; Procedure: Nocturnal Polysomnograpahy (NPSG)
Sponsor: New York University School of Medicine
Recruiting - Condition: Alzheimer Disease
Interventions: Other: tablet therapy; Other: usual care
Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting - Conditions: Frontotemporal Dementia; Behavioral Variant Frontotemporal Dementia
Intervention: Other: Assessments
Sponsor: Biogen
Recruiting - Condition: Alzheimer Disease
Intervention: Behavioral: Family-centered Function-focused Care (Fam-FFC)
Sponsors: Penn State University; National Institutes of Health (NIH)
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: elenbecestat (E2609); Drug: Placebo
Sponsors: Eisai Co., Ltd.; Biogen
Recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: Aerobic exercise; Behavioral: Stretch and Strength
Sponsors: University of Calgary; Canadian Institutes of Health Research (CIHR)
Recruiting - Conditions: Alzheimer Disease; Dementia
Interventions: Behavioral: Tele-Savvy; Behavioral: Healthy Living Education Program
Sponsors: Emory University; National Institute on Aging (NIA)
Recruiting - Condition: Dementia
Interventions: Drug: Carbamazepine; Drug: Mirtazapine; Other: Placebo
Sponsors: University of Sussex; Norwich Clinical Trials Unit; University of East Anglia; University of Cambridge; University College, London; London School of Economics and Political Science; University of Manchester; University of Newcastle Upon-Tyne; Birmingham and Solihull Mental Health NHS Foundation Trust; Alzheimer's Society; The Centre for Dementia Studies, Brighton and Sussex Medical School and SPFT
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: LY3303560 - IV; Drug: Placebo - IV; Drug: Florbetapir F 18; Drug: Flortaucipir F18
Sponsor: Eli Lilly and Company
Recruiting - Condition: Subjective Cognitive Decline
Intervention: Drug: 18F-Florbetaben (FBB)
Sponsor: Fundacion Clinic per a la Recerca Biomédica
Not yet recruiting - Conditions: Psychosis; Dementia; Aggression; Agitation; Alzheimer Dementia
Interventions: Drug: MP-101; Drug: Placebo
Sponsor: Mediti Pharma Inc.
Recruiting - Conditions: Alzheimer Disease (AD); Frontotemporal Lobar Degeneration; Dementia With Lewy Bodies (DLB); Parkinson Disease Dementia (PDD); Progressive Supranuclear Palsy (PSP); Corticobasal Degeneration (CBD)
Intervention:
Sponsors: Amoneta Diagnostics SAS; European Commission; Firalis SA; University Hospital, Strasbourg; Centre Hospitalier Universitaire Vaudois; IRCCS Centro San Giovanni di Dio Fatebenefratelli; Colmar Louis Pasteur Hospital; Istanbul University; Assistance Publique - Hôpitaux de Paris; University Hospital, Lille; University Hospital, Geneva; Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Erasme University Hospital
Recruiting - Conditions: Alzheimer's Disease; Lewy Body Dementia; Parkinson's Disease
Interventions: Radiation: DaTscan; Radiation: F18-AV-45; Radiation: FDG-PET; Genetic: APOE genotype; Procedure: Polysomnogram; Behavioral: Clinical Assessment
Sponsors: Douglas Scharre; Avid Radiopharmaceuticals; Mangurian Foundation
Not yet recruiting - Condition: Alzheimer Disease
Interventions: Drug: NPT088; Drug: Placebo
Sponsors: Proclara Biosciences, Inc.; Alzheimer's Association
Recruiting - Conditions: Alzheimer's Disease; Hearing Loss
Interventions: Device: Hearing aids; Device: Placebo
Sponsor: University Hospital, Tours
Recruiting - Condition: Irregular Sleep-Wake Rhythm Disorder
Interventions: Drug: Lemborexant 2.5 mg; Drug: Lemborexant 5 mg; Drug: Lemborexant 10 mg; Drug: Lemborexant 15 mg; Drug: Lemborexant-matched placebo
Sponsors: Eisai Inc.; Purdue Pharma LP
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Rivastigmine
Sponsor: Novartis Pharmaceuticals
Not yet recruiting - Condition: Alzheimer's Disease
Interventions: Device: Endurance Training; Other: therapeutic education meetings
Sponsor: University Hospital Center of Martinique
Recruiting - Condition: Preclinical Alzheimer's Disease
Intervention: Behavioral: Exergame
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - Conditions: Alzheimer's Disease; Parkinson's Disease; Frontotemporal Lobar Degeneration
Intervention: Behavioral: Observational Study
Sponsor: University Health Network, Toronto
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: elenbecestat (E2609); Drug: Placebo
Sponsors: Eisai Co., Ltd.; Biogen
Recruiting - Condition: Mild Cognitive Impairment
Intervention: Device: No intervention is part of this study but patients use an EEG device during observational data collection.
Sponsor: VA Boston Healthcare System
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Placebo Capsule(s) Once a Day by Mouth; Drug: Nilotinib Capsule(s) Once a Day by Mouth
Sponsor: Georgetown University
Recruiting - Condition: Alzheimer's Disease
Intervention: Procedure: visual search performance of everyday objects in realistic scenes
Sponsor: Centre Hospitalier Universitaire de Nice
Recruiting - Conditions: Mild Cognitive Impairment; Major Depressive Disorder; Alzheimer's Dementia; Transcranial Direct Current Stimulation; tDCS
Interventions: Other: Receive tDCS+CR; Other: Facilitate tDCS + CR
Sponsors: Centre for Addiction and Mental Health; CAMH Foundation
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Posiphen; Drug: Placebo
Sponsors: QR Pharma Inc.; Alzheimer's Disease Cooperative Study (ADCS)
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Interventions: Device: Sapphire II; Drug: Aftobetin-HCl; Radiation: Positron Emission Tomography
Sponsor: Cognoptix, Inc.
Recruiting - Conditions: Alzheimer's Disease; Cognitive Impairment
Intervention: Other: Mediterranean Diet
Sponsors: University of Kansas Medical Center; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Disease
Interventions: Device: rTMS active treatment; Device: rTMS sham treatment
Sponsors: University of Manitoba; Weston Brain Institute
Recruiting - Conditions: Cognitively Normal Older Adults; Hypertension; Subjective Cognitive Decline; Family History of Alzheimer's Disease
Interventions: Drug: Angiotensin II receptor blocker (ARB, losartan) and calcium channel blocker (CCB, amlodipine); Behavioral: Aerobic Exercise Training; Other: Usual Care; Behavioral: Stretching Exercise; Drug: Atorvastatin
Sponsors: University of Texas Southwestern Medical Center; Texas Health Resources; University of Kansas Medical Center; Washington University School of Medicine; Pennington Biomedical Research Center; Michigan State University
Recruiting - Conditions: Alzheimer Disease; ELECTROENCEPHALOGRAPHIC VARIANT PATTERN 1 (Disorder)
Intervention: Other: Rapid Visual Information Processing (RVIP) test
Sponsor: University Hospital, Lille
Recruiting - Condition: Alzheimer's Disease or Vascular Dementia
Interventions: Drug: BAC; Drug: Matched placebo
Sponsor: Charsire Biotechnology Corp.
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: ABBV-8E12; Drug: placebo for ABBV-8E12
Sponsor: AbbVie
Recruiting - Conditions: Alzheimer's Disease; Progressive Primary Aphasia; Early or Mild State
Intervention: Device: transcranial Direct Current Stimulation (tDCS)
Sponsors: Centre Hospitalier Universitaire de Besancon; Centre Hospitalier Universitaire Dijon; Assistance Publique - Hôpitaux de Paris
Recruiting - Conditions: Early Onset Alzheimer Disease; Mild Cognitive Impairment; Depression; Aging
Intervention:
Sponsor: ElMindA Ltd
Recruiting - Conditions: Mild Cognitive Impairment (MCI); Alzheimer's Disease (AD)
Intervention:
Sponsors: University of Southern California; Northern California Institute of Research and Education; National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute
Recruiting - Conditions: Alzheimer Disease; Depression
Intervention: Device: high-density electroencephalography
Sponsor: Centre Hospitalier Universitaire de Besancon
Recruiting - Conditions: Alzheimer Disease; Parkinson Disease
Intervention: Behavioral: Cognitive tests
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Recruiting - Conditions: Alteration of Cognitive Function; Hypoxia
Intervention: Other: 2-hour period of hypoxia
Sponsor: University Hospital, Lille
Recruiting - Condition: Alzheimer Disease
Interventions: Behavioral: AAT and cognitive stimulation and rehabilitation of social tie.; Behavioral: Cognitive stimulation and rehabilitation of social tie.
Sponsor: Hospices Civils de Lyon
Recruiting - Conditions: Bipolar Disorder; Alzheimer's Disease
Interventions: Procedure: lumbar puncture (LP); Procedure: brain MRI
Sponsor: University Hospital, Grenoble
Recruiting - Cognitive-motor Intervention Using Virtual Reality for Middle-aged Individuals at High Dementia RiskCondition: Alzheimer's Disease (AD)
Interventions: Behavioral: cognitive training by virtual reality; Behavioral: watching a scientific TV documentary; Device: treadmill
Sponsor: Sheba Medical Center
Recruiting - Condition: Agitation in Dementia, Including Alzheimer's Disease
Interventions: Drug: ITI-007; Drug: Placebo
Sponsor: Intra-Cellular Therapies, Inc.
Recruiting - Conditions: Cognitive Decline; Dementia; Alzheimer Disease; Vascular Dementia
Interventions: Behavioral: MIND Diet; Behavioral: Mild Weight Loss
Sponsors: Rush University Medical Center; Harvard School of Public Health; Brigham and Women's Hospital; National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Dementia
Intervention:
Sponsors: University of Edinburgh; Innovative Medicines Initiative
Recruiting - Condition: Alzheimer Disease
Intervention: Procedure: Malnutrition screening and perioperative nutritional support
Sponsor: Hospices Civils de Lyon
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Dronabinol (Marinol®); Drug: Placebo
Sponsors: Johns Hopkins University; Mclean Hospital
Recruiting - Condition: Alzheimer Disease
Interventions: Drug: BI 425809 dose 1; Drug: BI 425809 dose 2; Drug: BI 425809 dose 3; Drug: BI 425809 dose 4; Drug: Placebo
Sponsor: Boehringer Ingelheim
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Donepezil
Sponsor: Beijing Friendship Hospital
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Lanabecestat; Drug: Placebo
Sponsors: Eli Lilly and Company; AstraZeneca
Recruiting - Conditions: Mild Cognitive Impairment; Dementia; Alzheimer's Disease
Intervention:
Sponsor: University of Utah
Recruiting - Condition: Alzheimer's Disease
Interventions: Radiation: 10 GY in 5 daily fractions; Radiation: 20 GY in 10 daily fractions
Sponsor: Virginia Commonwealth University
Recruiting - Conditions: Mild Cognitive Impairment; Dementia; Alzheimer's Disease
Intervention: Drug: [18F]Flutemetamol
Sponsor: University of Utah
Recruiting - Conditions: Insomnia; Alzheimer's Disease
Interventions: Drug: Suvorexant 10 mg; Drug: Suvorexant 20 mg; Drug: Placebo
Sponsor: Merck Sharp & Dohme Corp.
Recruiting - Condition: Alzheimer's Disease
Intervention: Device: Actigraph
Sponsor: New York University School of Medicine
Not yet recruiting - Conditions: Atypical Alzheimer's Disease; Logopenic Progressive Aphasia (LPA); Posterior Cortical Atrophy (PCA)
Interventions: Drug: F-18 AV 1451; Drug: C-11 PiB
Sponsor: Mayo Clinic
Recruiting - Conditions: Parkinson's Disease; Alzheimer's Disease; Progressive Supranuclear Palsy; Essential Tremor; Multiple System Atrophy; Drug Induced Parkinson's Disease; Diffuse Lewy Body Disease; Myasthenia Gravis; Spinal Cord Injuries
Interventions: Other: Electrical Brainstem Responses; Other: Olfactory Tests; Other: Visual Deprivation; Other: Peripheral Nerve Stimulation
Sponsors: University of Pennsylvania; Michael J. Fox Foundation for Parkinson's Research
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: icosapent ethyl (IPE); Other: gel cap placebo
Sponsors: VA Office of Research and Development; University of Wisconsin, Madison
Recruiting - Condition: Dementia
Interventions: Drug: Xanamem™; Drug: Placebo (for Xanamem™)
Sponsors: Actinogen Medical; ICON Clinical Research
Recruiting - Conditions: Alzheimer's Disease; Amyotrophic Lateral Sclerosis; Brain Injury; Huntington's Disease; Multiple Sclerosis; Parkinson's Disease; Stroke; Spinal Cord Injury
Intervention: Other: Laughter Therapy
Sponsor: Brown, Theodore R., M.D., MPH
Recruiting - Condition: Dementia
Intervention: Device: Home monitoring kit
Sponsor: Lund University
Recruiting - Condition: Alzheimer's Disease
Interventions: Dietary Supplement: 1-month of 60-40 MCT oil; Dietary Supplement: 1-month of C8 MCT oil
Sponsors: Université de Sherbrooke; Fondation Vitae
Recruiting - Condition: Mild to Moderate Alzheimer's Disease
Intervention: Drug: Rivastigmine Patch
Sponsor: Novartis Pharmaceuticals
Recruiting - Condition: Alzheimer Disease
Intervention: Other: Neuropsychological assessment
Sponsor: Charite University, Berlin, Germany
Recruiting - Condition: Alzheimer's Disease
Intervention: Procedure: 18F-Flutemetamol & 18F-FDG
Sponsors: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Hospital Clinic of Barcelona; General Electric
Recruiting - Conditions: Dementia; Alzheimer's Disease
Interventions: Behavioral: UCF Caregiver Support Group; Behavioral: Community Support Groups
Sponsors: University of Central Florida; Alzheimer's and Dementia Resource Center
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Nicotine Transdermal Patch; Drug: Placebo Patch
Sponsors: University of Southern California; National Institute on Aging (NIA); Vanderbilt University; Alzheimer's Therapeutic Research Institute
Recruiting - Conditions: Aphasia, Primary Progressive; Anomia; Alzheimer Disease
Interventions: Behavioral: Phonological; Behavioral: Orthographic; Behavioral: Semantic; Behavioral: Lexical; Behavioral: Untrained
Sponsors: Georgetown University; National Institute on Deafness and Other Communication Disorders (NIDCD); Johns Hopkins University
Recruiting - Conditions: Amyloid Cerebral Angiopathy; Alzheimer Disease
Interventions: Device: Pet scan with FBB; Device: MRI scan; Biological: APO E genotyping
Sponsor: Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - Conditions: Mild Cognitive Impairment; Alzheimer Disease; Healthy
Interventions: Device: DVA; Device: FDOCT; Device: Pattern ERG; Device: Optical Coherence Tomography
Sponsor: Medical University of Vienna
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Neurodegenerative Diseases
Intervention: Drug: [18F]THK-5351
Sponsors: Jae Seung Kim; Korea Health Industry Development Institute; Samsung Medical Center
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Placebo; Drug: Candesartan
Sponsor: Emory University
Recruiting - Condition: Alzheimer Disease
Interventions: Other: Traditional Proton fMRI; Other: Hyperpolarized Xenon-129 fMRI; Drug: Hyperpolarized Xenon-129; Device: 1H-129Xe Dual-Tuned Quadrature Head Coil
Sponsors: Thunder Bay Regional Research Institute; Lakehead University; Thunder Bay Regional Health Sciences Centre
Recruiting - Condition: Alzheimer Disease
Interventions: Biological: LY3002813; Drug: Placebo
Sponsor: Eli Lilly and Company
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Piromelatine; Drug: Placebo
Sponsor: Neurim Pharmaceuticals Ltd.
Recruiting - Conditions: Alzheimer Disease; Down Syndrome; Mild Cognitive Impairment
Intervention:
Sponsor: University of Colorado, Denver
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: Longeveron Mesenchymal Stem Cells; Biological: Placebo
Sponsor: Longeveron LLC
Recruiting - Conditions: Breast Cancer; Colorectal Cancer; Prostate Cancer; Alzheimer Disease; Age-related Macular Degeneration; Parkinson Disease; Cardiac Disease; Ischemic Stroke; Hemorrhagic Stroke
Interventions: Behavioral: Support provided by social worker; Other: Information booklet receipt
Sponsors: Centre Hospitalier Universitaire de Besancon; Methodological and quality of life unit in oncology (CHRU de Besançon); University of Franche-Comté; University of Burgundy; Pôle de Gérontologie Interrégional Bourgogne et Franche-Comté; CARSAT Bourgogne et Franche-Comté; CCAS of Dijon; CCAS of Besançon; CCAS of Montbéliard; Burgundy Regional Council; Franche-Comté Regional Council; The Municipality of Besançon; The Municipality of Dijon; General Council of the Doubs; General Council of the Territoire de Belfort; Collectif Inter Associatif Sur la Sante Bourgogne; Union Régionale Interfédérale des Œuvres et Organismes Privés Sanitaires Bourgogne; Association Gérontopôle Pierre Pfitzenmeyer; Pôle de compétitivité Vitagora Goût-Nutrition-Santé; Caisse Nationale d’Assurance Vieillesse des Travailleurs Salariés (CNAVTS); Sheerbrooke Gérontopôle; France Alzheimer Côte-d’Or; Institut Régional de Vieillissement (IRV); Novartis Pharmaceuticals; Roche Foundation; Ligue contre le cancer, France; National Cancer Institute, France; Quality of life and cancer clinical research platform; National Research Agency, France
Recruiting - Conditions: Alzheimer Disease; Dementia; Heart Failure; Pulmonary Disease, Chronic Obstructive
Intervention: Behavioral: ACP Video Program
Sponsors: Brown University; National Institute on Aging (NIA); Hebrew SeniorLife; Massachusetts General Hospital; Genesis HealthCare; PruittHealth
Recruiting - Condition: Alzheimer's Disease (AD)
Intervention: Drug: Oxaloacetate (OAA)
Sponsor: Russell Swerdlow, MD
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: SUVN-502; Drug: Placebo
Sponsor: Suven Life Sciences Limited
Recruiting - Condition: Mild Cognitive Impairment
Intervention:
Sponsors: New York University School of Medicine; NeuroTrack Technologies, Inc.
Recruiting - Association Between Cerebral Arterial Vascular Flow and Sleep Apnea in Neurodegenerative AlterationsCondition: Alzheimer Disease
Intervention: Other: Vascular flow measurement by PC-MRI
Sponsor: Central Hospital Saint Quentin
Recruiting - Condition: Patients With Cognitive Disturbances
Interventions: Other: Neurological examinations; Other: Neuropsychological examinations; Other: Clinical examinations; Radiation: MRI 3T; Radiation: MRI 7T
Sponsor: Centre Hospitalier St Anne
Recruiting - Conditions: Alzheimer's Disease; Dementia; Dementia, Vascular; Caregivers; Veterans
Interventions: Behavioral: Counseling (C); Behavioral: Care Consultation (CC)
Sponsor: VA Office of Research and Development
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: CAD106 Immunotherapy; Other: Placebo to CAD106; Drug: CNP520; Other: Placebo to CNP520
Sponsors: Novartis Pharmaceuticals; Banner Alzheimer's Institute; National Institute on Aging (NIA); Alzheimer's Association; Amgen
Recruiting - Condition: Alzheimer Disease
Intervention:
Sponsor: Banner Health
Recruiting - Condition: Asymptomatic Amyloid-positive
Interventions: Drug: JNJ-54861911, 5 mg; Drug: JNJ-54861911, 25 mg; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Alzheimer's Disease
Interventions: Behavioral: An eye tracking experiment; Behavioral: A neuropsychological evaluation
Sponsor: Centre Hospitalier Universitaire de Nice
Recruiting - Condition: Amyloid PET Imaging
Intervention: Device: 18F-Florbetaben PET
Sponsor: Central Hospital, Nancy, France
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: ALZT-OP1a; Drug: ALZT-OP1b; Other: Placebo ALZT-OP1a; Other: Placebo ALZT-OP1b
Sponsors: AZTherapies, Inc.; PharmaConsulting Group; KCAS Bio; APCER Life Sciences
Recruiting - Condition: Alzheimer's Disease
Interventions: Procedure: Repetitive Transcranial Magnetic Stimulation; Procedure: Repetitive Transcranial Magnetic Stimulation - Sham
Sponsors: Centre for Addiction and Mental Health; Brain & Behavior Research Foundation; University of Toronto
Recruiting - Condition: Alzheimer's Disease
Interventions: Device: Erchonia ALS Laser; Device: Placebo Laser
Sponsor: Erchonia Corporation
Not yet recruiting - Conditions: Memory Disorders; Mild Cognitive Impairment; Alzheimer's Disease
Interventions: Behavioral: Intervention Group; Behavioral: Control Group
Sponsors: Boston University; Wallace H. Coulter Foundation
Recruiting - Condition: Alzheimer's Disease
Interventions: Behavioral: Combination of aerobic and strength exercises; Behavioral: Stretching and balance exercise program
Sponsors: University Hospital, Bordeaux; Poitiers University Hospital; Centre National de la Recherche Scientifique, France; University of Poitiers; University of Bordeaux
Recruiting - Conditions: Mild Cognitive Impairment; Probable Alzheimer's Disease
Interventions: Other: Modified Atkins Diet; Other: NIA Diet for Seniors
Sponsor: Johns Hopkins University
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: 18F-AV-1451
Sponsor: Avid Radiopharmaceuticals
Recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment; Vascular Cognitive Impairment; Parkinson's Disease; Lewy Body Disease
Intervention: Other: Flutemetamol PET scan
Sponsors: Sunnybrook Health Sciences Centre; Brain Canada; Weston Brain Institute; GE Healthcare; University Health Network, Toronto; Centre for Addiction and Mental Health; Baycrest; St. Michael's Hospital, Toronto; Kensington Eye Institute
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease (AD)
Interventions: Drug: Insulin glulisine; Drug: Placebo
Sponsor: HealthPartners Institute
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention: Drug: grape seed polyphenolic extract, resveratrol
Sponsors: Johns Hopkins University; Icahn School of Medicine at Mount Sinai
Recruiting - Condition: Alzheimer's Disease
Intervention:
Sponsors: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Obra Social La Caixa, Spain
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Aducanumab (BIIB037); Drug: Placebo
Sponsor: Biogen
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Aducanumab (BIIB037); Drug: Placebo
Sponsor: Biogen
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Telmisartan 20mg; Drug: Telmisartan 40mg; Drug: Placebo
Sponsor: Emory University
Recruiting - Conditions: Alzheimer's Disease; Vascular Dementia
Interventions: Drug: BAC; Other: BAC Matched Vehicle
Sponsors: Charsire Biotechnology Corp.; A2 Healthcare Taiwan Corporation
Not yet recruiting - Conditions: Alzheimer's Disease; Mild Cognitive Impairment
Interventions: Drug: Insulin aspart; Drug: Placebo
Sponsors: Wake Forest University Health Sciences; National Institute on Aging (NIA); General Electric
Recruiting - Conditions: Alzheimer's Disease; Obesity; Diabetes Mellitus
Interventions: Dietary Supplement: Boost A; Behavioral: Healthy Living Diet
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Intervention: Drug: AVP-786
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: Drug: AVP-786; Drug: Placebo
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: Drug: AVP-786; Drug: Placebo
Sponsor: Avanir Pharmaceuticals
Recruiting - Condition: Alzheimer's Disease
Intervention: Device: Thymatron IV device (Somatics)
Sponsor: Central Institute of Mental Health, Mannheim
Not yet recruiting - Conditions: Major Depression; Alzheimer's Disease; Alcoholism; Schizophrenia
Intervention:
Sponsor: Charite University, Berlin, Germany
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: F 18 T807
Sponsor: Washington University School of Medicine
Recruiting - Condition: Alzheimer Disease
Intervention: Drug: F 18 T807
Sponsor: Washington University School of Medicine
Recruiting - Conditions: Alzheimer Disease; Progressive Posterior Cortical Dysfunction (PPCD)
Intervention: Drug: F 18 T807
Sponsor: Washington University School of Medicine
Recruiting - Condition: Alzheimer Disease
Interventions: Biological: Lu AF20513, low dose; Biological: Lu AF20513, medium dose; Biological: Lu AF20513, high dose; Biological: Lu AF20513, double high dose
Sponsor: H. Lundbeck A/S
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Biological: Elderberry Juice; Other: Placebo
Sponsor: University of Missouri-Columbia
Recruiting - Conditions: Mild Cognitive Impairment; Major Depressive Disorder, Recurrent, In Remission; Major Depressive Disorder, Single Episode, in Full Remission
Interventions: Other: tDCS + CR; Other: sham tDCS + sham CR
Sponsors: Centre for Addiction and Mental Health; Brain Canada; Applied Health Research Centre; Queen's University; Baycrest Centre for Geriatric Care; St. Michael's Hospital, Toronto; Sunnybrook Health Sciences Centre; University Health Network, Toronto
Recruiting - Condition: Alzheimer Disease
Intervention: Radiation: Florbetaben
Sponsor: Judit Pich Martínez
Recruiting - Condition: Alzheimer's Disease
Interventions: Radiation: 5 daily fractions of 2 Gy; Radiation: 10 daily fractions of 2 Gy
Sponsor: William Beaumont Hospitals
Not yet recruiting - Conditions: Healthy; Neurodegenerative Disease
Intervention:
Sponsor: University of California, San Francisco
Recruiting - Conditions: Dementia; Alzheimer's Disease
Interventions: Behavioral: Preventing Loss of Independence through Exercise (PLIE); Behavioral: Usual Care Control
Sponsors: VA Office of Research and Development; Marin Adult Day Health Center, Novato, CA; Institute on Aging, San Francisco, CA; Catholic Charities, Santa Rosa, CA; Alzheimer's Services of the East Bay; Bayview Hunters Point Adult Day Health Center; Primrose Alzheimer’s Living, Inc
Recruiting - Conditions: Alzheimer's Disease; Dementia
Interventions: Other: Online counseling via Zoom teleconferencing; Other: Telephone support as needed
Sponsor: New York University School of Medicine
Recruiting - Conditions: Apathy; Alzheimer's Disease
Interventions: Drug: Methylphenidate; Drug: Placebo
Sponsors: Johns Hopkins Bloomberg School of Public Health; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Small Vessel Disease White Matter Hyperintensities Subtype; Vascular Cognitive Impairment
Intervention:
Sponsor: Dr. Sandra E Black
Recruiting - Conditions: Alzheimer Disease; Alzheimer Dementia; Alzheimer's Disease; Dementia
Interventions: Behavioral: Behavioral Activation; Behavioral: Information and Support
Sponsors: University of California, San Diego; National Institute on Aging (NIA)
Recruiting - Condition: Cognitive Impairment
Interventions: Procedure: acupuncture; Drug: donepezil
Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: Benfotiamine
Sponsors: Burke Medical Research Institute; Burke Rehabilitation Hospital; Columbia University; National Institute on Aging (NIA); Alzheimer’s Drug Discovery Foundation
Recruiting - Conditions: Mild to Moderate Alzheimer Disease; Cognitive Impairment
Interventions: Drug: Sodium oligo-mannurarate 900mg; Drug: Placebo
Sponsor: Shanghai Greenvalley Pharmaceutical Co., Ltd.
Recruiting - Condition: Mild Cognitive Impairment Due to Alzheimer's Disease
Interventions: Drug: Pioglitazone; Drug: Placebo
Sponsor: Takeda
Recruiting - Conditions: Alzheimer Disease; Battery
Interventions: Drug: Memantine; Drug: Placebo
Sponsor: University Hospital, Lille
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Procedure: Amyloid imaging; Procedure: FDG-PET
Sponsors: University of California, Los Angeles; Centers for Medicare and Medicaid Services
Not yet recruiting - Conditions: Alzheimer's Disease; Traumatic Brain Injury; Depression
Intervention: Drug: 18F-AV-1451
Sponsor: Avid Radiopharmaceuticals
Recruiting - Conditions: Alzheimer's Disease (AD); Alzheimer's Disease (AD) Related Disorders
Intervention: Other: in Memento-VASCOD
Sponsors: University Hospital, Bordeaux; Ministry for Health and Solidarity, France
Recruiting - Condition: Memory Impairment
Intervention: Other: The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6
Sponsor: Hospices Civils de Lyon
Recruiting - Condition: Dementia
Interventions: Drug: Cholinesterase inhibitor; Drug: Sham discontinuation
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention: Device: Transcranial direct current stimulation (tDCS) Soterix Medical Inc. tDCS unit
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Alzheimer's Disease; Psychosis; Agitation
Interventions: Drug: Lithium; Drug: Placebo
Sponsors: New York State Psychiatric Institute; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Plaque, Amyloid
Intervention:
Sponsor: Janssen Research & Development, LLC
Recruiting - Condition: Genetic Risk for Alzheimer's Disease
Interventions: Drug: donepezil HCL; Drug: Placebo
Sponsors: The Cleveland Clinic; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimer's Disease; Hypertension
Interventions: Drug: Perindopril; Drug: Telmisartan
Sponsors: Sunnybrook Health Sciences Centre; Alzheimer’s Drug Discovery Foundation; Weston Brain Institute
Recruiting - Condition: Alzheimer's Disease
Interventions: Biological: human umbilical cord blood derived mesenchymal stem cells; Other: Normal saline 2mL
Sponsor: Medipost Co Ltd.
Recruiting - Conditions: Alzheimer's Disease; Cerebrovascular Disease; Lewy Body Disease
Intervention: Radiation: SPECT-DaTscan
Sponsor: Hospices Civils de Lyon
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Meganatural-Az Grapeseed Extract; Drug: Placebo
Sponsors: Hillel Grossman; National Center for Complementary and Integrative Health (NCCIH)
Recruiting - Conditions: Alzheimer's Disease; Dementia
Intervention:
Sponsor: Banner Health
Recruiting - Condition: Alzheimer's Disease
Interventions: Other: Aerobic Exercise; Other: Standard of Care
Sponsors: University of Kansas Medical Center; National Institute on Aging (NIA)
Recruiting - Conditions: Alzheimers Disease; Postoperative Delirium; Post Operative Cognitive Dysfunction
Interventions: Drug: Total intravenous anesthesia with propofol; Drug: General anesthesia with isoflurane
Sponsor: Duke University
Recruiting - Conditions: Ataxia; Dystonia; Parkinson's Disease; Amyotrophic Lateral Sclerosis; Corticobasal Degeneration; Multiple System Atrophy; Alzheimer's Disease; Lewy Body Dementia; Parkinson Disease-Dementia; Dentatorubral-pallidoluysian Atrophy; Creutzfeldt-Jakob Disease and Fatal Familial Insomnia; Fragile X-associated Tremor/Ataxia Syndrome; Krabbe's Disease; Niemann-Pick Disease, Type C; Neuronal Ceroid Lipofuscinosis
Intervention:
Sponsor: National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Disease, Late Onset
Interventions: Behavioral: Cycling exercise; Behavioral: Range of motion/stretching exercise
Sponsors: University of Minnesota - Clinical and Translational Science Institute; Mayo Clinic; University of St Thomas
Recruiting - Conditions: Alzheimer Disease; Mild Cognitive Impairment; Delirium, Dementia, Amnestic, Cognitive Disorders
Intervention: Drug: Donepezil
Sponsors: New York State Psychiatric Institute; National Institutes of Health (NIH); National Institute on Aging (NIA)
Recruiting - Condition: Alzheimer's Disease
Intervention: Other: Personalized Exercise Regimen
Sponsor: University Health Network, Toronto
Recruiting - Condition: All Diagnosed Health Conditions
Intervention:
Sponsor: Sanguine Biosciences
Recruiting - Conditions: Alzheimer's Disease; Dementia
Interventions: Drug: Spinal anesthesia group: bupivacaine 10-15mg; Drug: General anesthesia group: induction propofol 1.5-2mg/kg and fentanyl 1-3g/kg, maintained with isoflurane or sevoflurane; Genetic: Blood test; Other: Lumbar spinal tap; Behavioral: Montreal Cognitive Assessment (MOCA) and MMSE
Sponsor: University Health Network, Toronto
Recruiting - Condition: Mild Cognitive Impairment
Interventions: Drug: Curcumin; Behavioral: aerobic yoga; Behavioral: non aerobic yoga; Dietary Supplement: Placebo
Sponsor: VA Office of Research and Development
Recruiting - Conditions: Alzheimers Disease; Dementia; Alzheimers Disease, Familial
Interventions: Drug: Gantenerumab; Drug: Solanezumab; Drug: Matching Placebo (Gantenerumab); Drug: Matching Placebo (Solanezumab); Drug: JNJ-54861911; Drug: Matching Placebo (JNJ-54861911)
Sponsors: Washington University School of Medicine; Eli Lilly and Company; Hoffmann-La Roche; Alzheimer's Association; National Institute on Aging (NIA); Avid Radiopharmaceuticals; Accelerating Medicines Partnership (AMP); Janssen Research and Development
Recruiting - Condition: Alzheimer's Disease
Intervention: Drug: BNC
Sponsor: National Institute on Aging (NIA)
Recruiting - Conditions: Down Syndrome; Mild Cognitive Impairment
Interventions: Drug: Low Dose Nicotine (7mg); Drug: Moderate Dose Nicotine (14mg)
Sponsor: Vanderbilt University Medical Center
Recruiting - Conditions: Alzheimer Disease; Oxidative Stress; Adrenocortical Hyperfunction
Intervention:
Sponsor: Raffaele Antonelli Incalzi
Recruiting - Condition: Alzheimer's Disease
Interventions: Drug: Riluzole; Drug: Placebo
Sponsor: Rockefeller University
Recruiting - Conditions: Traumatic Brain Injury; Post Traumatic Stress Disorder; Alzheimer's Disease; Mild Cognitive Impairment
Intervention:
Sponsors: University of Southern California; United States Department of Defense; Telemedicine & Advanced Technology Research Center; Northern California Institute of Research and Education; San Francisco Veterans Affairs Medical Center; Alzheimer's Therapeutic Research Institute
Recruiting - Condition: Postoperative Cognitive Dysfunction
Interventions: Drug: Florbetapir F 18 (18F-AV-45); Other: no intervention
Sponsors: University of California, San Francisco; Alzheimer’s Drug Discovery Foundation; Avid Radiopharmaceuticals
Recruiting - Conditions: Alzheimer's Disease; Inborn Errors of Metabolism; Mitochondrial Disorders; Undiagnosed Diseases
Intervention:
Sponsor: National Human Genome Research Institute (NHGRI)
Recruiting - Conditions: Alzheimer Disease; Depression
Intervention: Other: Eye movements will be recorded using video-oculography techniques based on both the corneal reflection principle and an infra-red light beam
Sponsors: Centre Hospitalier Universitaire de Besancon; Laboratoire de psychologie EA 3188; Centre Hospitalier Universitaire Dijon; Centre Hospitalier de Novillars
Recruiting - Conditions: Alzheimer's Disease; Cardiovascular Risk Factors
Interventions: Other: optimal care of VRF; Other: standard care
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Conditions: Ischemic Stroke; Hemorrhagic Stroke
Intervention:
Sponsor: Ludwig-Maximilians - University of Munich
Recruiting - Conditions: Cerebrovascular Disorders; Dementia
Intervention:
Sponsors: University Hospital, Lille; Ministry of Health, France
Recruiting - Condition: Alzheimer's Disease
Intervention:
Sponsors: Washington University School of Medicine; National Institute on Aging (NIA)
Recruiting - Condition: Neurodegenerative Disorders
Intervention:
Sponsor: Hadassah Medical Organization
Recruiting - Conditions: Alzheimer Disease; Late Onset Alzheimer Disease; Dementia
Intervention:
Sponsors: Indiana University; National Institute on Aging (NIA)
Recruiting
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