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- Condition: Pilon Fracture
Interventions: Drug: N-acetylcysteine; Drug: Saline
Sponsor: University of Missouri-Columbia
Not yet recruiting - Condition: Asthma
Intervention: Drug: N-acetylcysteine
Sponsors: University of California, San Francisco; National Institutes of Health (NIH)
Recruiting - Condition: Biliary Atresia
Intervention: Drug: N-Acetyl cysteine
Sponsor: Baylor College of Medicine
Recruiting - Condition: Mild Cognitive Impairment
Intervention: Dietary Supplement: N- acetylcysteine plus Glycine v Placebo (alanine)
Sponsors: Baylor College of Medicine; Nantz National Alzheimer's Center, Methodist Hospital, Houston, TX
Recruiting - Condition: Acute Respiratory Distress Syndrome
Intervention: Drug: N-acetyl cysteine
Sponsor: Palmetto Health
Recruiting - Conditions: Diabetes Mellitus; Critical Limb Ischemia; Lower Limb Amputation Knee; Peripheral Arterial Disease
Interventions: Drug: Active Arm N-acetyl cysteine (NAC); Drug: Placebo Arm
Sponsor: Washington University School of Medicine
Recruiting - Condition: Chronic Traumatic Brain Injury
Interventions: Other: Anti-inflammatory Diet; Dietary Supplement: N-acetyl Cysteine
Sponsor: Thomas Jefferson University
Recruiting - Conditions: Alcohol Drinking; Control
Interventions: Drug: N-Acetylcysteine; Drug: Placebo Oral Capsule
Sponsors: Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Alcohol Use Disorder
Interventions: Drug: Alcohol; Drug: Placebos; Drug: N-acetyl cysteine
Sponsors: William Stoops; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Conditions: Alcohol Use Disorder; Bipolar Disorder
Interventions: Drug: N-Acetylcysteine; Drug: Gabapentin; Drug: Placebo Oral Tablet
Sponsors: Medical University of South Carolina; National Institutes of Health (NIH); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - Condition: Marijuana Abuse
Intervention: Drug: N-acetyl cysteine
Sponsor: Wayne State University
Recruiting - Condition: Parkinson Disease
Interventions: Dietary Supplement: N-Acetylcysteine; Procedure: Lumbar Puncture
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - Condition: Cannabis Use Disorder
Interventions: Drug: N-acetyl cysteine; Drug: Placebo oral capsule
Sponsor: Medical University of South Carolina
Recruiting - Condition: Multiple Sclerosis
Intervention: Dietary Supplement: N-acetyl Cysteine
Sponsor: Thomas Jefferson University
Recruiting - Condition: Autism Spectrum Disorder
Interventions: Drug: N-acetylcysteine; Drug: Placebo
Sponsor: Emory University
Recruiting - Condition: Cocaine Dependence
Interventions: Dietary Supplement: N-acetylcysteine; Other: Placebo
Sponsor: Yale University
Recruiting - Conditions: Post Traumatic Stress Disorder (PTSD); Addiction; Alcohol Abuse
Interventions: Drug: N-Acetylcysteine (NAC) Treatment; Behavioral: Cognitive Behavioral Therapy; Drug: Placebo Oral Capsule
Sponsors: Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes of Health (NIH)
Recruiting - Conditions: Posttraumatic Stress Disorder (PTSD); Alcohol Use Disorder (AUD); Substance Use Disorder (SUD)
Interventions: Drug: N-acetylcysteine; Drug: Placebo; Behavioral: Cognitive behavioral therapy
Sponsors: Medical University of South Carolina; United States Department of Defense; Institute for Translational Neuroscience
Recruiting - Condition: Depression
Intervention: Drug: N-acetyl cysteine
Sponsor: University of Cincinnati
Recruiting - Conditions: Traumatic Brain Injury (TBI); Hazardous and Harmful Alcohol Use
Interventions: Behavioral: Medical Management Counseling; Drug: N-acetylcysteine; Drug: Placebo
Sponsors: University of California, San Francisco; United States Department of Defense; Northern California Institute of Research and Education; San Francisco Veterans Affairs Medical Center; Institute for Translational Neuroscience
Recruiting - Conditions: Nicotine Dependence; Smoking
Interventions: Drug: N-acetylcysteine (NAC); Other: Placebo
Sponsors: Medical University of South Carolina; National Institute on Drug Abuse (NIDA)
Recruiting - Conditions: Thoracic Surgery; Atrial Fibrillation in High Risk Patients
Interventions: Drug: Amiodarone; Drug: N-Acetylcysteine; Drug: Placebo
Sponsors: Memorial Sloan Kettering Cancer Center; Washington University School of Medicine; The Cleveland Clinic; Vanderbilt University School of Medicine
Recruiting - A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar DepressionConditions: Bipolar Disorder; Bipolar Depression
Interventions: Dietary Supplement: N-acetylcysteine; Drug: Minocycline; Other: Placebo
Sponsor: Massachusetts General Hospital
Recruiting - Condition: Nicotine Dependence, Cigarettes
Interventions: Drug: Varenicline (VRN); Drug: N-Acetylcysteine (NAC); Drug: Placebo
Sponsor: Medical University of South Carolina
Recruiting - Condition: Gaucher Disease Type 1
Intervention: Drug: N-acetylcysteine
Sponsors: University of Minnesota - Clinical and Translational Science Institute; Rare Diseases Clinical Research Network; National Center for Advancing Translational Science (NCATS); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Neurological Disorders and Stroke (NINDS); Lysosomal Disease Network
Recruiting - Conditions: Schizophrenia; Cognitive Deficits; Schizophrenia; Negative Type
Interventions: Drug: N-acetylcysteine; Other: Treatment as Usual
Sponsor: University of California, Los Angeles
Recruiting - Condition: Bipolar Disorder
Intervention: Drug: Open-label Treatment with N-Acetylcysteine
Sponsor: Massachusetts General Hospital
Recruiting - Conditions: Aging; Erythrocyte Glutathione Deficiency; Muscle Weakness
Intervention: Dietary Supplement: Cysteine (as n-acetylcysteine) and Glycine
Sponsor: Baylor College of Medicine
Recruiting - Conditions: Mucopolysaccharidosis Disorders; Hurler Syndrome; Hunter Syndrome; Maroteaux Lamy Syndrome; Sly Syndrome; Alpha-Mannosidosis; Fucosidosis; Aspartylglucosaminuria; Glycoprotein Metabolic Disorders; Sphingolipidoses; Recessive Leukodystrophies; Globoid Cell Leukodystrophy; Metachromatic Leukodystrophy; Niemann-Pick B; Niemann-Pick C Subtype 2; Sphingomyelin Deficiency; Peroxisomal Disorders; Adrenoleukodystrophy With Cerebral Involvement; Zellweger Syndrome; Neonatal Adrenoleukodystrophy; Infantile Refsum Disease; Acyl-CoA Oxidase Deficiency; D-Bifunctional Enzyme Deficiency; Multifunctional Enzyme Deficiency; Alpha-methylacyl-CoA Racmase Deficiency; Mitochondrial Neurogastrointestingal Encephalopathy; Severe Osteopetrosis; Hereditary Leukoencephalopathy With Axonal Spheroids (HDLS; CSF1R Mutation); Inherited Metabolic Disorders
Interventions: Biological: Stem Cell Transplantation; Drug: IMD Preparative Regimen; Drug: Osteopetrosis Only Preparative Regimen; Drug: Osteopetrosis Haploidentical Only Preparative Regimen; Drug: cALD SR-A (Standard-Risk, Regimen A); Drug: cALD SR-B (Standard-Risk, Regimen B); Drug: cALD HR-D (High-Risk, Regimen C); Drug: cALD HR-D (High-Risk, Regimen D)
Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting - Conditions: Cocaine Dependence; Healthy
Interventions: Drug: N-acetyl cysteine; Diagnostic Test: [18F]FDG PET scan; Diagnostic Test: 1H MRS; Diagnostic Test: [11C]APP311 PET scan
Sponsor: Yale University
Recruiting - Conditions: Neuroectodermal Tumors, Primitive; Liver Neoplasms; Osteosarcoma; Other Childhood Cancers Using Cisplatin-based Regimens
Intervention: Drug: N-Acetylcysteine
Sponsor: Children's Hospital Los Angeles
Recruiting - Condition: Aging
Intervention: Dietary Supplement: Glycine, cysteine (as n-acetylcysteine), alanine
Sponsors: Rajagopal V Sekhar; National Institute on Aging (NIA)
Recruiting
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